5-Fluorouracil-induced apoptosis in cultured oral cancer cells

Oral Oncology

Volumn 36, Issue 2, 2000, Pages 236-241

  Tong, D ^a   Poot, M ^b   Hu, D ^b   Oda, D ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Caspase inhibitor; Epithelial; Flow cytometry; Oral cancer

Indexed keywords

CASPASE; CASPASE INHIBITOR; FLUOROURACIL;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CELL CYCLE; CELL DEATH; CHEMOSENSITIVITY; CONTROLLED STUDY; DOSE RESPONSE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MOUTH CANCER; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA;

ANTIMETABOLITES, ANTINEOPLASTIC; APOPTOSIS; CARCINOMA, SQUAMOUS CELL; CASPASES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FLUOROURACIL; HUMANS; INDOLES; MOUTH NEOPLASMS; OLIGOPEPTIDES; TUMOR CELLS, CULTURED;

EID: 0034163546     PISSN: 13688375     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1368-8375(99)00079-2     Document Type: Article

References (24)

1. Parkin D.M., Pisani P., Ferlay J. Estimates of the worldwide incidence of 18 major cancers in 1985. International Journal of Cancer. 54:1993;594-606.
2. Morse D., Pendrys D.G., Neely A.L., Psoter W.J. Trends in the incidence of lip, oral and pharyngeal cancer: Connecticut, 1935-94. Oral Oncology. 35:1999;1-8.
3. McAndrew P.G. Oral cancer and precancer: treatment. British Dental Journal. 168:1990;191-198.
4. Strong E. Surgical management of oral cancer. Dental Clinics of North America. 34:1990;185-203.
5. Gluckman J.L., Savoury L.W. Carcinoma of the oral cavity. Paparella M.M. Otolaryngology. 1991;2041-2067 WB Saunders, Philadelphia.
6. Posner M.R., Colevas A.D. Induction chemotherapy in the management of squamous cell cancer of the head and neck. The Cancer Journal from Scientific American. 3:1997;73-75.
7. MacDonald JS, editor. Manual of oncologic therapeutics, 3rd ed. Philadelphia: JB Lippincott, 1991. p. 111-13.
8. Merlano M., Benasso M., Cavallari M., Blengio F., Rosso M. Chemotherapy in head and neck cancer. European Journal of Cancer B, Oral Oncology. 30B:1994;283-289.
9. Perry MC, editor. The chemotherapy source book. 2nd ed. Baltimore: Williams and Wilkins, 1996. p. 318, 323-325.
10. Darzynkiewicz Z., Juan G., Li X., Gorczyca W., Murakami T., Tragonos F. Cytometry in cell necrobiology: analysis of apoptosis and accidental cell death (necrosis). Cytometry. 27:1997;1-20.
11. Bowen ID, Bowen SM. Programmed cell death in tumours and tissues. London: Chapman and Hall, 1990. p. 1-68.
12. Hockenbery D. Defining apoptosis. American Journal of Pathology. 146:1995;16-19.
13. Dong Z., Saikumar P., Weinberg J.M., Venkatachalam M.A. Internucleosomal DNA cleavage triggered by plasma membrane damage during necrotic cell death. American Journal of Pathology. 151:1997;1205-1213.
14. Poot M., Gibson L.L., Singer V.L. Detection of apoptosis in live cells by Mito Tracker red CMXRos and SYTO dye flow cytometry. Cytometry. 27:1997;358-364.
15. Darzynkiewicz Z., Bruno S., Del Bino G., Gorczyca W., Hotz M.A., Lassota P., Tragonos F. Features of apoptotic cells measured by flow cytometry. Cytometry. 13:1992;795-808.
16. Drake W., Ungaro P.C., Mardiney M.R. Formalin fixed cell preparations as standards for use in the automated trypan blue cytotoxic assay. Transplantation. 14:1972;127-130.
17. Rabinovitch P. DNA content histogram and cell cycle analysis. Methods in Cell Biology. 41:1994;263-296.
18. Mossman T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. Journal of Immunological Methods. 65:1983;55-63.
19. Inada T., Ichikawa A., Kubota T., Ogata Y., Moosa A.R., Hoffman R.M. 5FU induced apoptosis correlates with efficacy against human gastric and colon cancer xenografts in nude mice. Anticancer Research. 17:1997;1965-1971.
20. Inada T., Ichikawa A., Igarashi S., Kubota T., Ogata Y. Effect of preoperative 5-fluorouracil on apoptosis of advanced gastric cancer. Journal of Surgical Oncology. 65:1997;106-110.
21. Okamoto S., Sakai M., Uchida J., Saito H. 5-fluorouracil induces apoptotic cell death with G2 phase arrest in human breast cancer grafted in nude mice. Anticancer Research. 16:1996;2699-2704.
22. Ohtani T, Hatori M, Ohashi M, Kamijo R Involvement of caspases in 5FU induced apoptosis (Abstract). 1999 IADR Meeting, Vancouver, BC, Canada.
23. Nuyts R.M.M.A., Pels E., Greve E.L. The effects of 5-fluorouracil and mitomycin C on the corneal endothelium. Current Eye Research. 6:1992;565-570.
24. Havrilesky L.J., Elbendary A., Hurteau J.A., Whitaker R.S., Rodriguez G.C., Berchuck A. Chemotherapy induced apoptosis in epithelial ovarian cancers. Obstetrics and Gynecology. 85:1995;1007-1010.