A novel anti-tumor protein extracted from Meretrix meretrix Linnaeus induces cell death by increasing cell permeability and inhibiting tubulin polymerization

International Journal of Oncology

Volumn 35, Issue 4, 2009, Pages 805-812

  Ning, Xuanxuan ^a,b   Zhao, Jianmin ^a   Zhang, Yuyan ^a   Cao, Subing ^a   Liu, Ming ^a   Ling, Peixue ^c   Lin, Xiukun ^a  

^a INSTITUTE OF OCEANOLOGY   (China)

^b Yantai Oceanic Environmental Monitoring Central Station of SOA   (China)

^c Shandong Province Hospital   (China)

Author keywords

Anti tumor protein; Apoptosis; Cell cycle; Cell membrane permeability; Cytotoxicity; Meretrix meretrix Linnaeus; Tubulin polymerization

Indexed keywords

ALPHA TUBULIN; AMMONIUM SULFATE; ANTINEOPLASTIC AGENT; MERETRIX MERETRIX EXTRACT; TISSUE EXTRACT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL DEATH; CELL MEMBRANE PERMEABILITY; CELL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; HYDROPHOBICITY; ION EXCHANGE CHROMATOGRAPHY; MARINE SPECIES; MERETRIX MERETRIX; MOLECULAR WEIGHT; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN POLYMERIZATION; PROTEIN PURIFICATION;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BIVALVIA; CELL CYCLE; CELL DEATH; CELL MEMBRANE PERMEABILITY; CELL SHAPE; CHEMICAL FRACTIONATION; CHROMATOGRAPHY, ION EXCHANGE; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; HCT116 CELLS; HUMANS; HYDROPHOBICITY; MICE; MICROTUBULES; MOLECULAR WEIGHT; NIH 3T3 CELLS; PROTEINS; TUBULIN; TUBULIN MODULATORS;

EID: 70449448957     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo_00000393     Document Type: Article

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