Selective activation of Toll-like receptor 7 in activated hepatic stellate cells may modulate their profibrogenic phenotype

Biochemical Journal

Volumn 447, Issue 1, 2012, Pages 25-34

  Chou, Ming Huei ^a,b   Huang, Ying Hsien ^a   Lin, Tsun Mei ^b,c   Du, Yung Ying ^a   Tsai, Po Chin ^a   Hsieh, Chih Sung ^d   Chuang, Jiin Haur ^a  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^c I SHOU UNIVERSITY   (Taiwan)

^d PINGTUNG CHRISTIAN HOSPITAL   (Taiwan)

Author keywords

CL075; Hepatic stellate cell; Short hairpin RNA (shRNA); Toll like receptor 7 (TLR7)

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CL 075; COLLAGEN; COLLAGEN ALPHA1 CHAIN; F ACTIN; GELATINASE A; MONOCYTE CHEMOTACTIC PROTEIN 1; SHORT HAIRPIN RNA; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR AGONIST; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CHOLESTASIS; CONTROLLED STUDY; DOWN REGULATION; DRUG ACTIVITY; FIBROGENESIS; MALE; NONHUMAN; OBSTRUCTIVE JAUNDICE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; STELLATE CELL; UPREGULATION;

ACTINS; ANIMALS; CELL LINE; CELL MOVEMENT; CELL PROLIFERATION; COLLAGEN TYPE I; GENE EXPRESSION; HEPATIC STELLATE CELLS; JAUNDICE, OBSTRUCTIVE; LIVER CIRRHOSIS; MALE; PHENOTYPE; QUINOLINES; RATS; RATS, SPRAGUE-DAWLEY; RNA, SMALL INTERFERING; THIAZOLES; TOLL-LIKE RECEPTOR 7;

RATTUS;

EID: 84866387027     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20112058     Document Type: Article

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