Chiral-substrate-assisted stereoselective epoxidation catalyzed by H 2O 2-dependent cytochrome P450 SPα

Chemistry - An Asian Journal

Volumn 7, Issue 10, 2012, Pages 2286-2293

  Fujishiro, Takashi ^a   Shoji, Osami ^a   Kawakami, Norifumi ^a   Watanabe, Takahiro ^a   Sugimoto, Hiroshi ^b   Shiro, Yoshitsugu ^b   Watanabe, Yoshihito ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b RIKEN SPring 8 Center   (Japan)

Author keywords

carboxylic acids; chirality; decoy molecules; epoxidation; hydrogen peroxide

Indexed keywords

ACID-BASE CATALYSTS; ACTIVE SITE; CARBOXYLATE GROUPS; CYTOCHROME P450; DOCKING SIMULATIONS; STEREO-SELECTIVE; STYRENE OXIDE; VINYL GROUP;

CARBOXYLATION; CARBOXYLIC ACIDS; CATALYSIS; CHIRALITY; ENANTIOMERS; EPOXIDATION; HYDROGEN PEROXIDE; MOLECULES; STEREOSELECTIVITY; STYRENE;

STEREOCHEMISTRY;

CARBOXYLIC ACID; EPOXIDE; FATTY ACID ALPHA HYDROXYLASE; FATTY ACID ALPHA-HYDROXYLASE; HYDROGEN PEROXIDE; IBUPROFEN; MIXED FUNCTION OXIDASE; STYRENE;

ARTICLE; BINDING SITE; BIOCATALYSIS; CHEMISTRY; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; METABOLISM; MOLECULAR DOCKING; OXIDATION REDUCTION REACTION; STEREOISOMERISM; X RAY CRYSTALLOGRAPHY;

BINDING SITES; BIOCATALYSIS; CARBOXYLIC ACIDS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; EPOXY COMPOUNDS; HYDROGEN PEROXIDE; IBUPROFEN; MIXED FUNCTION OXYGENASES; MOLECULAR DOCKING SIMULATION; OXIDATION-REDUCTION; STEREOISOMERISM; STYRENE; SUBSTRATE SPECIFICITY;

EID: 84866381924     PISSN: 18614728     EISSN: 1861471X     Source Type: Journal    
DOI: 10.1002/asia.201200250     Document Type: Article

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