Glycogen synthase kinase-3β activation mediates rotenone-induced cytotoxicity with the involvement of microtubule destabilization

Biochemical and Biophysical Research Communications

Volumn 426, Issue 1, 2012, Pages 94-99

  Hongo, Haruyuki ^a   Kihara, Takeshi ^b   Kume, Toshiaki ^a   Izumi, Yasuhiko ^a   Niidome, Tetsuhiro ^c   Sugimoto, Hachiro ^d   Akaike, Akinori ^a,e  

^a KYOTO UNIVERSITY   (Japan)

^b Misasagi Hospital   (Japan)

^c EISAI CO LTD   (Japan)

^d DOSHISHA UNIVERSITY   (Japan)

^e NAGOYA UNIVERSITY   (Japan)

Author keywords

Glycogen synthase kinase 3 ; Microtubule destabilization; Parkinson's disease; Rotenone; Tau

Indexed keywords

2 (2,4 DICHLOROPHENYL) 3 (1 METHYL 3 INDOLYL)MALEIMIDE; GLYCOGEN SYNTHASE KINASE 3BETA; PACLITAXEL; ROTENONE; TAU PROTEIN; TUBULIN;

ARTICLE; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; HUMAN; HUMAN CELL; MICROTUBULE; MICROTUBULE DESTABILIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

CELL LINE, TUMOR; ELECTRON TRANSPORT COMPLEX I; GLYCOGEN SYNTHASE KINASE 3; HUMANS; INDOLES; MALEIMIDES; MICROTUBULES; PACLITAXEL; PARKINSON DISEASE, SECONDARY; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES; ROTENONE; TAU PROTEINS; TUBULIN MODULATORS;

ANIMALIA;

EID: 84866343400     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.08.042     Document Type: Article

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