Engineering Escherichia coli to increase plasmid DNA production in high cell-density cultivations in batch mode

Microbial Cell Factories

Volumn 11, Issue , 2012, Pages

  Borja, Gheorghe M ^a   Meza Mora, Eugenio ^b   Barrón, Blanca ^c   Gosset, Guillermo ^b   Ramírez, Octavio T ^a   Lara, Alvaro R ^d  

^a Departamento de Medicina Molecular y Bioprocesos   (Mexico)

^b INSTITUTO DE BIOTECNOLOGÍA   (Mexico)

^c INSTITUTO POLITÉCNICO NACIONAL   (Mexico)

^d DEPARTAMENTO DE PROCESOS Y TECNOLOGÍA   (Mexico)

Author keywords

Acetate; Batch cultivation; DNA vaccines; E. coli; Overflow metabolism; Plasmid DNA

Indexed keywords

ACETIC ACID; GLUCOSE; PLASMID DNA; ANTIGEN; CARRIER PROTEIN; DEOR PROTEIN, E COLI; DNA VACCINE; ESCHERICHIA COLI PROTEIN; NUPG PROTEIN, E COLI; RECA PROTEIN; REPRESSOR PROTEIN;

ARTICLE; BACTERIAL CELL; BACTERIAL GROWTH; BACTERIAL STRAIN; BIOMASS; CELL DENSITY; CELL ENGINEERING; DNA SUPERCOILING; DNA SYNTHESIS; ESCHERICHIA COLI; FED BATCH CULTURE; GENE MUTATION; GLUCOSE TRANSPORT; GROWTH RATE; NONHUMAN; BIOREACTOR; BIOSYNTHESIS; GENE INACTIVATION; GENETIC ENGINEERING; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MICROBIOLOGY; MUMPS VIRUS; PLASMID;

ESCHERICHIA COLI;

ANTIGENS; BIOMASS; BIOREACTORS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE KNOCKOUT TECHNIQUES; GENETIC ENGINEERING; GLUCOSE; MEMBRANE TRANSPORT PROTEINS; MUMPS VIRUS; PLASMIDS; REC A RECOMBINASES; REPRESSOR PROTEINS; VACCINES, DNA;

EID: 84866297923     PISSN: None     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/1475-2859-11-132     Document Type: Article

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