Deficiency of terminal complement pathway inhibitor promotes neuronal tau pathology and degeneration in mice

Journal of Neuroinflammation

Volumn 9, Issue , 2012, Pages

  Britschgi, Markus ^a   Takeda Uchimura, Yoshiko ^a   Rockenstein, Edward ^b   Johns, Hudson ^a   Masliah, Eliezer ^b   Wyss Coray, Tony ^a,c  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c VA PALO ALTO HEALTH CARE SYSTEM   (United States)

Author keywords

Age related neurodegeneration; Alzheimer's disease; Complement system; Frontotemporal lobar degeneration; Innate immune system; Mouse models of tau pathology; Tauopathy

Indexed keywords

CD59 ANTIGEN; CD59A ANTIGEN; COMPLEMENT RECEPTOR; COMPLEMENT RECEPTOR 1 RELATED GENE; TAU PROTEIN; UNCLASSIFIED DRUG;

AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; BRAIN NERVE CELL; BRAIN STEM; CELL COUNT; CELL LOSS; CEREBELLUM; COMPLEMENT SYSTEM; CONTROLLED STUDY; HIPPOCAMPAL CA2 REGION; HIPPOCAMPAL CA3 REGION; HISTOLOGY; IMMUNOREACTIVITY; MOUSE; NONHUMAN; PROTEIN PHOSPHORYLATION; SYNAPTIC POTENTIAL; TAUOPATHY; TERMINAL COMPLEMENT PATHWAY; TRANSGENIC MOUSE; WILD TYPE;

EID: 84866274911     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-9-220     Document Type: Article

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