-
1
-
-
77952936573
-
PI3K pathwaydirected therapeutic strategies in cancer
-
Agarwal,R.,Carey,M.,Hennessy,B.,and Mills, G. B. (2010). PI3K pathwaydirected therapeutic strategies in cancer. Curr. Opin. Investig. Drugs 11, 615-628.
-
(2010)
Curr. Opin. Investig. Drugs
, vol.11
, pp. 615-628
-
-
Agarwal, R.1
Carey, M.2
Hennessy, B.3
Mills, G.B.4
-
2
-
-
77955622867
-
Second salvage surgery for re-recurrent oral cavity and oropharynx carcinoma
-
Agra, I. M., Filho, J. G., Martins, E. P., and Kowalski, L. P. (2010). Second salvage surgery for re-recurrent oral cavity and oropharynx carcinoma. Head Neck 32, 997-1002.
-
(2010)
Head Neck
, vol.32
, pp. 997-1002
-
-
Agra, I.M.1
Filho, J.G.2
Martins, E.P.3
Kowalski, L.P.4
-
3
-
-
7944222114
-
Prediction of drug sensitivity and drug resistance in cancer by transcriptional and pro-teomic profiling
-
Alaoui-Jamali, M. A., Dupré, I., and Qiang,H.(2004). Prediction of drug sensitivity and drug resistance in cancer by transcriptional and pro-teomic profiling. Drug Resist. Updat. 7, 245-255.
-
(2004)
Drug Resist. Updat.
, vol.7
, pp. 245-255
-
-
Alaoui-Jamali, M.A.1
Dupré, I.2
Qiang, H.3
-
4
-
-
84860371953
-
Epigenetic protein families: a new frontier for drug discovery
-
Arrowsmith, C. H., Bountra, C., Fish, P. V., Lee, K., and Schapira, M. (2012). Epigenetic protein families: a new frontier for drug discovery. Nat. Rev. Drug Discov. 11, 384-400.
-
(2012)
Nat. Rev. Drug Discov.
, vol.11
, pp. 384-400
-
-
Arrowsmith, C.H.1
Bountra, C.2
Fish, P.V.3
Lee, K.4
Schapira, M.5
-
5
-
-
58749097656
-
The canonical WNT/beta-catenin signalling pathway
-
Barker, N. (2008). The canonical WNT/beta-catenin signalling pathway. Methods Mol. Biol. 468, 5-15.
-
(2008)
Methods Mol. Biol.
, vol.468
, pp. 5-15
-
-
Barker, N.1
-
6
-
-
53649095183
-
Hyperbaric oxygenation for tumor sensitisation to radiotherapy: a systematic review of randomised controlled trials
-
Bennett, M., Feldmeier, J., Smee, R., and Milross, C. (2008). Hyperbaric oxygenation for tumor sensitisation to radiotherapy: a systematic review of randomised controlled trials. Cancer Treat. Rev. 34, 577-591.
-
(2008)
Cancer Treat. Rev.
, vol.34
, pp. 577-591
-
-
Bennett, M.1
Feldmeier, J.2
Smee, R.3
Milross, C.4
-
7
-
-
39049165254
-
Consensus guidelines for the management of radiation dermatitis and coexisting acnelike rash in patients receiving radiotherapy plus EGFR inhibitors for the treatment of squamous cell carcinoma of the head and neck
-
Bernier, J., Bonner, J., Vermorken, J. B., Bensadoun, R. J., Dummer, R., Giralt, J., Kornek, G., Hartley, A., Mesia, R., Robert, C., Segaert, S., and Ang,K. K. (2008). Consensus guidelines for the management of radiation dermatitis and coexisting acnelike rash in patients receiving radiotherapy plus EGFR inhibitors for the treatment of squamous cell carcinoma of the head and neck. Ann. Oncol. 19, 142-149.
-
(2008)
Ann. Oncol.
, vol.19
, pp. 142-149
-
-
Bernier, J.1
Bonner, J.2
Vermorken, J.B.3
Bensadoun, R.J.4
Dummer, R.5
Giralt, J.6
Kornek, G.7
Hartley, A.8
Mesia, R.9
Robert, C.10
Segaert, S.11
Ang, K.K.12
-
8
-
-
0036897097
-
Protracted low-dose effects on human endothelial cell proliferation and survival in vitro reveal a selective antiangiogenic window for various chemotherapeutic drugs
-
Bocci, G., Nicolaou, K. C., and Kerbel, R. S. (2002). Protracted low-dose effects on human endothelial cell proliferation and survival in vitro reveal a selective antiangiogenic window for various chemotherapeutic drugs. Cancer Res. 62, 6938-6943.
-
(2002)
Cancer Res
, vol.62
, pp. 6938-6943
-
-
Bocci, G.1
Nicolaou, K.C.2
Kerbel, R.S.3
-
9
-
-
0034668172
-
Induction and regulation of epithelialmesenchymal transitions
-
Boyer, B., Valles, A. M., and Edme, N. (2000). Induction and regulation of epithelialmesenchymal transitions. Biochem. Pharmacol. 60, 1091-1099.
-
(2000)
Biochem. Pharmacol.
, vol.60
, pp. 1091-1099
-
-
Boyer, B.1
Valles, A.M.2
Edme, N.3
-
10
-
-
0034488576
-
A phase II study of razoxane, an antiangiogenic topoisomerase II inhibitor, in renal cell cancer with assessment of potential surrogate markers of angiogenesis
-
Braybrooke,J.P.,O'Byrne,K.J., Propper, D. J., Blann, A., Saunders, M., Dobbs, N., Han, C., Woodhull, J., Mitchell, K., Crew, J., Smith, K., Stephens, R., Ganesan, T. S., Talbot, D. C., and Harris, A. L. (2000). A phase II study of razoxane, an antiangiogenic topoisomerase II inhibitor, in renal cell cancer with assessment of potential surrogate markers of angiogenesis. Clin. Cancer Res. 6, 4697-4704.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 4697-4704
-
-
Braybrooke, J.P.1
O'Byrne, K.J.2
Propper, D.J.3
Blann, A.4
Saunders, M.5
Dobbs, N.6
Han, C.7
Woodhull, J.8
Mitchell, K.9
Crew, J.10
Smith, K.11
Stephens, R.12
Ganesan, T.S.13
Talbot, D.C.14
Harris, A.L.15
-
11
-
-
0034032882
-
Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drugresistant cancer
-
Browder, T., Butterfield, C. E., Kräling, B. M., Shi, B., Marshall, B., O'Reilly, M. S., and Folkman, J. (2000). Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drugresistant cancer. Cancer Res. 60, 1878-1886.
-
(2000)
Cancer Res
, vol.60
, pp. 1878-1886
-
-
Browder, T.1
Butterfield, C.E.2
Kräling, B.M.3
Shi, B.4
Marshall, B.5
O'Reilly, M.S.6
Folkman, J.7
-
12
-
-
9344247476
-
Genetic progression model for head and neck cancer: implications for field cancerization
-
Califano, J., van der Riet, P., Westra, W., Nawroz, H., Clayman, G., Piantadosi, S., Corio, R., Lee, D., Green-berg, B., Koch, W., and Sidransky, D. (1996). Genetic progression model for head and neck cancer: implications for field cancerization. Cancer Res. 56, 2488-2492.
-
(1996)
Cancer Res
, vol.56
, pp. 2488-2492
-
-
Califano, J.1
van der Riet, P.2
Westra, W.3
Nawroz, H.4
Clayman, G.5
Piantadosi, S.6
Corio, R.7
Lee, D.8
Green-Berg, B.9
Koch, W.10
Sidransky, D.11
-
13
-
-
0033966575
-
Genetic progression and clonal relationship of recurrent premalignant head and neck lesions
-
Califano, J., Westra, W. H., Meininger, G., Corio, R., Koch, W. M., and Sidransky, D. (2000). Genetic progression and clonal relationship of recurrent premalignant head and neck lesions. Clin. Cancer Res. 6, 347-352.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 347-352
-
-
Califano, J.1
Westra, W.H.2
Meininger, G.3
Corio, R.4
Koch, W.M.5
Sidransky, D.6
-
14
-
-
20444395761
-
Treatment results on advanced neck metastasis (N3) from head and neck squamous carcinoma
-
Carvalho, A. L., Kowalski, L. P., Agra, I. M., Pontes, E., Campos, O. D., and Pellizzon, A. C. (2005). Treatment results on advanced neck metastasis (N3) from head and neck squamous carcinoma. Otolaryngol. Head Neck Surg. 132, 862-868.
-
(2005)
Otolaryngol. Head Neck Surg.
, vol.132
, pp. 862-868
-
-
Carvalho, A.L.1
Kowalski, L.P.2
Agra, I.M.3
Pontes, E.4
Campos, O.D.5
Pellizzon, A.C.6
-
15
-
-
77954014147
-
Trastuzumab-based neoadjuvant therapy in patients with HER2-positive breast cancer
-
Chang, H. R. (2010). Trastuzumab-based neoadjuvant therapy in patients with HER2-positive breast cancer. Cancer 116, 2856-2867.
-
(2010)
Cancer
, vol.116
, pp. 2856-2867
-
-
Chang, H.R.1
-
16
-
-
0036120562
-
The cadherincatenin adhesion system in signaling and cancer
-
Conacci-Sorrell, M., Zhurinsky, J., and Ben-Ze'Ev,A. (2002). The cadherincatenin adhesion system in signaling and cancer. J. Clin. Invest. 109, 987-991.
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 987-991
-
-
Conacci-Sorrell, M.1
Zhurinsky, J.2
Ben-Ze'Ev, A.3
-
17
-
-
84855912001
-
Pericyte depletion results in hypoxia-associated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway
-
Cooke, V. G., LeBleu, V. S., Keskin, D., Khan, Z., O'Connell, J. T., Teng, Y., Duncan, M. B., Xie, L., Maeda, G., Vong, S., Sugimoto, H., Rocha, R. M., Damascena, A., Brentani, R. R., and Kalluri, R. (2012). Pericyte depletion results in hypoxia-associated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway. Cancer Cell 21, 66-82.
-
(2012)
Cancer Cell
, vol.21
, pp. 66-82
-
-
Cooke, V.G.1
LeBleu, V.S.2
Keskin, D.3
Khan, Z.4
O'Connell, J.T.5
Teng, Y.6
Duncan, M.B.7
Xie, L.8
Maeda, G.9
Vong, S.10
Sugimoto, H.11
Rocha, R.M.12
Damascena, A.13
Brentani, R.R.14
Kalluri, R.15
-
18
-
-
77949881462
-
The PI3K pathway as drug target in human cancer
-
Courtney, K. D., Corcoran, R. B., and Engelman, J. A. (2010). The PI3K pathway as drug target in human cancer. J. Clin. Oncol. 28, 1075-1083.
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 1075-1083
-
-
Courtney, K.D.1
Corcoran, R.B.2
Engelman, J.A.3
-
19
-
-
16844368698
-
Tumor stem cells and drug resistance
-
Dean, M., Fojo, T., and Bates, S. (2005). Tumor stem cells and drug resistance. Nat. Rev. Cancer 5, 275-284.
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 275-284
-
-
Dean, M.1
Fojo, T.2
Bates, S.3
-
20
-
-
77952374261
-
Integrationof epidermal growth factor receptor inhibitors with preop-erative chemoradiation
-
Debucquoy, A., Machiels, J. P., McBride, W. H., and Haustermans, K. (2010). Integrationof epidermal growth factor receptor inhibitors with preop-erative chemoradiation.Clin. Cancer Res. 16, 2709-2714.
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 2709-2714
-
-
Debucquoy, A.1
Machiels, J.P.2
McBride, W.H.3
Haustermans, K.4
-
21
-
-
77950914672
-
PI3K/Akt signalling pathway specific inhibitors: a novel strategy to sensitize cancer cells to anti-cancer drugs
-
Falasca, M. (2010). PI3K/Akt signalling pathway specific inhibitors: a novel strategy to sensitize cancer cells to anti-cancer drugs. Curr. Pharm. Des. 16, 1410-1416.
-
(2010)
Curr. Pharm. Des.
, vol.16
, pp. 1410-1416
-
-
Falasca, M.1
-
22
-
-
80055080834
-
A review of clinical and histological parameters associated with contralateral neck metas-tases in oral squamous cell carcinoma
-
Fan, S., Tang, Q. L., Lin, Y. J., Chen, W. L., Li, J. S., Huang, Z. Q., Yang, Z. H., Wang,Y. Y., Zhang, D. M., Wang, H. J., Dias-Ribeiro, E., Cai, Q., and Wang, L. (2011). A review of clinical and histological parameters associated with contralateral neck metas-tases in oral squamous cell carcinoma. Int. J. Oral Sci. 3, 180-191.
-
(2011)
Int. J. Oral Sci.
, vol.3
, pp. 180-191
-
-
Fan, S.1
Tang, Q.L.2
Lin, Y.J.3
Chen, W.L.4
Li, J.S.5
Huang, Z.Q.6
Yang, Z.H.7
Wang, Y.Y.8
Zhang, D.M.9
Wang, H.J.10
Dias-Ribeiro, E.11
Cai, Q.12
Wang, L.13
-
23
-
-
33947732977
-
Angiogenesis: an organizing principle for drug discovery?
-
Folkman, J. (2007). Angiogenesis: an organizing principle for drug discovery? Nat. Rev. Drug Discov. 6, 273-286.
-
(2007)
Nat Rev. Drug Discov.
, vol.6
, pp. 273-286
-
-
Folkman, J.1
-
24
-
-
80053925902
-
Cancer stem cells, models of study and implications of therapy resistance mechanisms
-
Frame,F. M., and Maitland,N.J.(2011). Cancer stem cells, models of study and implications of therapy resistance mechanisms. Adv. Exp. Med. Biol. 720, 105-118.
-
(2011)
Adv. Exp. Med. Biol.
, vol.720
, pp. 105-118
-
-
Frame, F.M.1
Maitland, N.J.2
-
25
-
-
79955651331
-
Interventions for the treatment of oral cavity and oropharyngeal cancer: chemotherapy
-
Furness, S., Glenny,A. M., Worthington, H. V., Pavitt, S., Oliver, R., Clarkson, J. E., Macluskey, M., Chan, K. K., and Conway, D. I. (2011). Interventions for the treatment of oral cavity and oropharyngeal cancer: chemotherapy. Cochrane Database Syst. Rev. 4, CD006386.
-
(2011)
Cochrane Database Syst. Rev.
, vol.4
-
-
Furness, S.1
Glenny, A.M.2
Worthington, H.V.3
Pavitt, S.4
Oliver, R.5
Clarkson, J.E.6
Macluskey, M.7
Chan, K.K.8
Conway, D.I.9
-
26
-
-
84863652136
-
Circumventing cancer drug resistance in the era of personalized medicine
-
Garraway, L. A., and Jänne, P. A. (2012). Circumventing cancer drug resistance in the era of personalized medicine. Cancer Discov. 2, 214-226.
-
(2012)
Cancer Discov
, vol.2
, pp. 214-226
-
-
Garraway, L.A.1
Jänne, P.A.2
-
27
-
-
33746344657
-
Clinicopathological parameters and outcome of 245 patients operated for oral squamous cell carcinoma
-
Garzino-Demo, P., Dell'Acqua, A., Dalmasso, P., Fasolis, M., La Terra Maggiore, G. M., Ramieri, G., Berrone, S., Rampino, M., and Schena, M. (2006). Clinicopathological parameters and outcome of 245 patients operated for oral squamous cell carcinoma. J. Craniomaxillofac Surg. 34, 344-350.
-
(2006)
J. Craniomaxillofac Surg.
, vol.34
, pp. 344-350
-
-
Garzino-Demo, P.1
Dell'Acqua, A.2
Dalmasso, P.3
Fasolis, M.4
La Terra Maggiore, G.M.5
Ramieri, G.6
Berrone, S.7
Rampino, M.8
Schena, M.9
-
28
-
-
0034117603
-
Clinical perspectives on platinum resistance
-
Giaccone, G. (2000). Clinical perspectives on platinum resistance. Drugs 59, 37-38.
-
(2000)
Drugs
, vol.59
, pp. 37-38
-
-
Giaccone, G.1
-
29
-
-
81755163602
-
Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance
-
Gillet, J. P., Calcagno, A. M., Varma, S., Marino, M., Green, L. J., Vora, M. I., Patel, C., Orina, J. N., Eliseeva, T. A., Singal, V., Padmanabhan, R., Davidson, B., Ganapathi, R., Sood, A. K., Rueda, B. R., Ambudkar, S. V., and Gottesman, M. M. (2011). Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance. Proc. Natl. Acad. Sci. U.S.A. 108, 18708-18713.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 18708-18713
-
-
Gillet, J.P.1
Calcagno, A.M.2
Varma, S.3
Marino, M.4
Green, L.J.5
Vora, M.I.6
Patel, C.7
Orina, J.N.8
Eliseeva, T.A.9
Singal, V.10
Padmanabhan, R.11
Davidson, B.12
Ganapathi, R.13
Sood, A.K.14
Rueda, B.R.15
Ambudkar, S.V.16
Gottesman, M.M.17
-
30
-
-
0038299190
-
Disparity in pathologic and clinical lymph node staging in oral tongue carcinoma Implication for therapeutic decision making
-
Greenberg, J. S., El-Naggar,A. K., Mo,V., Roberts, D., and Myers, J. N. (2003). Disparity in pathologic and clinical lymph node staging in oral tongue carcinoma. Implication for therapeutic decision making. Cancer 98, 508-515.
-
(2003)
Cancer
, vol.98
, pp. 508-515
-
-
Greenberg, J.S.1
El-Naggar, A.K.2
Mo, V.3
Roberts, D.4
Myers, J.N.5
-
31
-
-
82455199147
-
Induced pluripotent stem cells - opportunities for disease modelling and drug discovery
-
Grskovic, M., Javaherian, A., Strulovici, B., and Daley, G. Q. (2011). Induced pluripotent stem cells - opportunities for disease modelling and drug discovery. Nat. Rev. Drug Discov. 10, 915-929.
-
(2011)
Nat. Rev. Drug Discov.
, vol.10
, pp. 915-929
-
-
Grskovic, M.1
Javaherian, A.2
Strulovici, B.3
Daley, G.Q.4
-
32
-
-
0034048358
-
Less is more, regularly: metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice
-
Hanahan, D., Bergers, G., and Bergsland, E. (2000). Less is more, regularly: metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice. J. Clin. Invest. 105, 1045-1047.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 1045-1047
-
-
Hanahan, D.1
Bergers, G.2
Bergsland, E.3
-
33
-
-
77951498331
-
Inhibitors of phosphatidylinositol-3-kinase in cancer therapy
-
Ihle, N. T., and Powis, G. (2010). Inhibitors of phosphatidylinositol-3-kinase in cancer therapy. Mol. Aspects Med. 31, 135-144.
-
(2010)
Mol. Aspects Med.
, vol.31
, pp. 135-144
-
-
Ihle, N.T.1
Powis, G.2
-
34
-
-
0033374718
-
Chemotherapy of advanced non-small cell lung cancer
-
Jassem, J. (1999). Chemotherapy of advanced non-small cell lung cancer. Ann. Oncol. 10, 77-82.
-
(1999)
Ann. Oncol.
, vol.10
, pp. 77-82
-
-
Jassem, J.1
-
35
-
-
84859127474
-
Tumorderived microvesicles induce proangiogenic phenotype in endothelial cells via endocytosis
-
doi:10.1371/journal.pone.0034045
-
Kawamoto, T., Ohga, N., Akiyama, K., Hirata, N., Kitahara, S., Maishi, N., Osawa, T., Yamamoto, K., Kondoh, M., Shindoh, M., Hida, Y., and Hida, K. (2012). Tumorderived microvesicles induce proangiogenic phenotype in endothelial cells via endocytosis. PLoS ONE 7, doi:10.1371/journal.pone.0034045
-
(2012)
PLoS ONE
, vol.7
-
-
Kawamoto, T.1
Ohga, N.2
Akiyama, K.3
Hirata, N.4
Kitahara, S.5
Maishi, N.6
Osawa, T.7
Yamamoto, K.8
Kondoh, M.9
Shindoh, M.10
Hida, Y.11
Hida, K.12
-
36
-
-
20444490772
-
Targeting angiogenesis in cancer: clinical development of bevacizumab
-
Kerr, D. J. (2004). Targeting angiogenesis in cancer: clinical development of bevacizumab. Nat. Clin. Pract. Oncol. 1, 39-43.
-
(2004)
Nat. Clin. Pract. Oncol.
, vol.1
, pp. 39-43
-
-
Kerr, D.J.1
-
37
-
-
18844373390
-
Predictive factors for distant metastasis from oral and oropharyngeal squamous cell carcinoma
-
Kowalski, L. P., Carvalho, A. L., Martins Priante, A. V., and Magrin, J. (2005). Predictive factors for distant metastasis from oral and oropharyngeal squamous cell carcinoma. Oral Oncol. 41, 534-541.
-
(2005)
Oral Oncol
, vol.41
, pp. 534-541
-
-
Kowalski, L.P.1
Carvalho, A.L.2
Martins Priante, A.V.3
Magrin, J.4
-
38
-
-
7344222653
-
Squamous cell carcinoma of the tongue: a review of 629 patients treated at a single institution
-
Kowalski, L. P., Magrin, J., Sabóia, M., Santos, J. C., and Torloni, H. (1998). Squamous cell carcinoma of the tongue: a review of 629 patients treated at a single institution. South Am. J. Cancer 107, 697-702.
-
(1998)
South Am. J. Cancer
, vol.107
, pp. 697-702
-
-
Kowalski, L.P.1
Magrin, J.2
Sabóia, M.3
Santos, J.C.4
Torloni, H.5
-
40
-
-
77349115530
-
Current and emerging treatment strategies for cutaneous T-cell lymphoma
-
Lansigan, F., and Foss,F. M. (2010). Current and emerging treatment strategies for cutaneous T-cell lymphoma. Drugs 70, 273-286.
-
(2010)
Drugs
, vol.70
, pp. 273-286
-
-
Lansigan, F.1
Foss, F.M.2
-
41
-
-
27844461512
-
Epithelialmesenchymal transition in development and cancer: role of phosphatidylinositol 3' kinase/AKT pathways
-
Larue, L., and Bellacosa, A. (2005). Epithelialmesenchymal transition in development and cancer: role of phosphatidylinositol 3' kinase/AKT pathways. Oncogene 24, 7443-7454.
-
(2005)
Oncogene
, vol.24
, pp. 7443-7454
-
-
Larue, L.1
Bellacosa, A.2
-
42
-
-
0032168673
-
Clinical development of platinum complexes in cancer therapy: an historical perspective and an update
-
Lebwohl, D., and Canetta, R. (1998). Clinical development of platinum complexes in cancer therapy: an historical perspective and an update. Eur. J. Cancer 34, 1522-1534.
-
(1998)
Eur. J. Cancer
, vol.34
, pp. 1522-1534
-
-
Lebwohl, D.1
Canetta, R.2
-
43
-
-
0028031635
-
Recurrence at the primary site in head and neck cancer and the significance of neck lymph node metastases as a prognostic factor
-
Leemans, C. R., Tiwari, R., Nauta, J. J., van der Waal, I., and Snow, G. B. (1994). Recurrence at the primary site in head and neck cancer and the significance of neck lymph node metastases as a prognostic factor. Cancer 73, 187-190.
-
(1994)
Cancer
, vol.73
, pp. 187-190
-
-
Leemans, C.R.1
Tiwari, R.2
Nauta, J.J.3
van der Waal, I.4
Snow, G.B.5
-
44
-
-
80054034905
-
Vemurafenib in melanoma with BRAF V600E mutation
-
Lott, J. P. (2011). Vemurafenib in melanoma with BRAF V600E mutation. N. Engl. J. Med. 365, 1449-1450.
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 1449-1450
-
-
Lott, J.P.1
-
45
-
-
57749092182
-
Combination of antiangiogenesis with chemotherapy for more effective cancer treatment
-
Ma, J., and Waxman,D. J. (2008). Combination of antiangiogenesis with chemotherapy for more effective cancer treatment. Mol. Cancer Ther. 7, 3670-3684.
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 3670-3684
-
-
Ma, J.1
Waxman, D.J.2
-
46
-
-
79960446890
-
New advances in targeted therapies for squamous cell carcinoma of the head and neck
-
Machiels, J. P., and Schmitz, S. (2011). New advances in targeted therapies for squamous cell carcinoma of the head and neck. Anticancer Drugs 22, 626-633.
-
(2011)
Anticancer Drugs
, vol.22
, pp. 626-633
-
-
Machiels, J.P.1
Schmitz, S.2
-
47
-
-
84857913363
-
Latest advances and current challenges in the treatment of multiple myeloma
-
Mahindra, A., Laubach, J., Raje, N., Munshi, N., Richardson, P. G., and Anderson, K. (2012). Latest advances and current challenges in the treatment of multiple myeloma. Nat. Rev. Clin. Oncol. 9, 135-143.
-
(2012)
Nat. Rev. Clin. Oncol.
, vol.9
, pp. 135-143
-
-
Mahindra, A.1
Laubach, J.2
Raje, N.3
Munshi, N.4
Richardson, P.G.5
Anderson, K.6
-
48
-
-
84860591982
-
Semaphorin 3A overcomes cancer hypoxia and metastatic dissemination induced by antiangiogenic treatment in mice
-
Maione, F., Capano, S., Regano, D., Zentilin, L., Giacca, M., Casanovas, O., Bussolino, F., Serini, G., and Giraudo, E. (2012). Semaphorin 3A overcomes cancer hypoxia and metastatic dissemination induced by antiangiogenic treatment in mice. J. Clin. Invest. 125, 1832-1848.
-
(2012)
J. Clin. Invest.
, vol.125
, pp. 1832-1848
-
-
Maione, F.1
Capano, S.2
Regano, D.3
Zentilin, L.4
Giacca, M.5
Casanovas, O.6
Bussolino, F.7
Serini, G.8
Giraudo, E.9
-
49
-
-
43049165453
-
The epithelialmesenchymal transition generates cells with properties of stem cells
-
Mani, S. A., Guo, W., Liao, M. J., Eaton, E. N., Ayyanan, A., Zhou, A. Y., Brooks, M., Reinhard, F., Zhang, C. C., Shipitsin, M., Campbell, L. L., Polyak, K., Brisken, C., Yang, J., and Weinberg, R. A. (2008). The epithelialmesenchymal transition generates cells with properties of stem cells. Cell 133, 704-715.
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
Eaton, E.N.4
Ayyanan, A.5
Zhou, A.Y.6
Brooks, M.7
Reinhard, F.8
Zhang, C.C.9
Shipitsin, M.10
Campbell, L.L.11
Polyak, K.12
Brisken, C.13
Yang, J.14
Weinberg, R.A.15
-
50
-
-
0029769788
-
Telomerase activity in head and neck squamous cell carcinoma and adjacent tissues
-
Mao, L., El-Naggar, A. K., Fan, Y. H., Lee, J. S., Lippman, S. M., Kayser, S., Lotan, R., and Hong, W. K. (1996). Telomerase activity in head and neck squamous cell carcinoma and adjacent tissues. Cancer Res. 56, 5600-5604.
-
(1996)
Cancer Res
, vol.56
, pp. 5600-5604
-
-
Mao, L.1
El-Naggar, A.K.2
Fan, Y.H.3
Lee, J.S.4
Lippman, S.M.5
Kayser, S.6
Lotan, R.7
Hong, W.K.8
-
51
-
-
84863888220
-
Combining antiangiogenics to overcome resistance: rationale and clinical experience
-
Moreno Garcia, V., Basu, B., Molife, L. R., and Kaye, S. B. (2012). Combining antiangiogenics to overcome resistance: rationale and clinical experience. Clin. Cancer Res. 18, 3750-3761.
-
(2012)
Clin. Cancer Res.
, vol.18
, pp. 3750-3761
-
-
Moreno Garcia, V.1
Basu, B.2
Molife, L.R.3
Kaye, S.B.4
-
52
-
-
0036124520
-
Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors
-
Morikawa, S., Baluk, P., Kaidoh, T., Haskell, A., Jain, R. K., and McDonald, D. M. (2002). Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors. Am. J. Pathol. 160, 985-1000.
-
(2002)
Am. J. Pathol.
, vol.160
, pp. 985-1000
-
-
Morikawa, S.1
Baluk, P.2
Kaidoh, T.3
Haskell, A.4
Jain, R.K.5
McDonald, D.M.6
-
53
-
-
77953452311
-
Advances and perspectives in the molecular diagnosis of head and neck cancer
-
Mydlarz, W. K., Hennessey, P. T., and Califano, J. A. (2010). Advances and perspectives in the molecular diagnosis of head and neck cancer. Expert Opin. Med. Diagn. 4, 53-65.
-
(2010)
Expert Opin. Med. Diagn.
, vol.4
, pp. 53-65
-
-
Mydlarz, W.K.1
Hennessey, P.T.2
Califano, J.A.3
-
54
-
-
22144461325
-
Transforming growth factorbeta signaling during epithelialmesenchymal transformation: implications for embryogenesis and tumor metastasis
-
Nawshad, A., Lagamba, D., Polad, A., and Hay,E. D. (2005). Transforming growth factorbeta signaling during epithelialmesenchymal transformation: implications for embryogenesis and tumor metastasis. Cells Tissues Organs (Print) 179, 11-23.
-
(2005)
Cells Tissues Organs (Print)
, vol.179
, pp. 11-23
-
-
Nawshad, A.1
Lagamba, D.2
Polad, A.3
Hay, E.D.4
-
55
-
-
1542347695
-
Convergence of WNT, β-catenin, and cadherin pathways
-
Nelson, W. J., and Nusse, R. (2004). Convergence of WNT, β-catenin, and cadherin pathways. Science 303, 1483-1487.
-
(2004)
Science
, vol.303
, pp. 1483-1487
-
-
Nelson, W.J.1
Nusse, R.2
-
56
-
-
0034052286
-
The relationship of genetic aberrations detected by comparative genomic hybridization to DNA ploidy and tumor size in human oral squamous cell carcinomas
-
Okafuji, M., Ita, M., Oga, A., Hayatsu, Y., Matsuo, A., Shinzato, Y., Shinozaki, F., and Sasaki, K. (2000). The relationship of genetic aberrations detected by comparative genomic hybridization to DNA ploidy and tumor size in human oral squamous cell carcinomas. J. Oral Pathol. Med. 29, 226-231.
-
(2000)
J. Oral Pathol. Med.
, vol.29
, pp. 226-231
-
-
Okafuji, M.1
Ita, M.2
Oga, A.3
Hayatsu, Y.4
Matsuo, A.5
Shinzato, Y.6
Shinozaki, F.7
Sasaki, K.8
-
57
-
-
14944385553
-
Global cancer statistics 2002
-
Parkin, D. M., Bray, F., Ferlay, J., and Pisani, P. (2005). Global cancer statistics, 2002. CA Cancer J. Clin. 55, 74-108.
-
(2005)
CA Cancer J. Clin.
, vol.55
, pp. 74-108
-
-
Parkin, D.M.1
Bray, F.2
Ferlay, J.3
Pisani, P.4
-
58
-
-
0032949934
-
Cisplatininduced activation of mitogenactivated protein kinases in ovarian carcinoma cells: inhibition of extracellular signalregulated kinase activity increases sensitivity to cisplatin
-
Persons, D. L., Yazlovitskaya, E. M., Cui, W., and Pelling, J. C. (1999). Cisplatininduced activation of mitogenactivated protein kinases in ovarian carcinoma cells: inhibition of extracellular signalregulated kinase activity increases sensitivity to cisplatin. Clin. Cancer Res. 5, 1007-1014.
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 1007-1014
-
-
Persons, D.L.1
Yazlovitskaya, E.M.2
Cui, W.3
Pelling, J.C.4
-
59
-
-
67349149654
-
Oral cancer prevention and control - the approach of the World Health Organization
-
Petersen, P. E. (2009). Oral cancer prevention and control - the approach of the World Health Organization. Oral Oncol. 45, 454-460.
-
(2009)
Oral Oncol
, vol.45
, pp. 454-460
-
-
Petersen, P.E.1
-
60
-
-
63049123066
-
Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits
-
Polyak, K., and Weinberg, R. A. (2009). Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat. Rev. Cancer 9, 265-273.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 265-273
-
-
Polyak, K.1
Weinberg, R.A.2
-
61
-
-
33846512398
-
Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma
-
Prince, M. E., Sivanandan, R., Kaczorowski, A., Wolf, G. T., Kaplan, M. J., Dalerba, P., Weissman, I. L., Clarke,M. F., and Ailles,L. E. (2007). Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. Proc. Natl. Acad. Sci. U.S.A. 104, 973-978.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 973-978
-
-
Prince, M.E.1
Sivanandan, R.2
Kaczorowski, A.3
Wolf, G.T.4
Kaplan, M.J.5
Dalerba, P.6
Weissman, I.L.7
Clarke, M.F.8
Ailles, L.E.9
-
62
-
-
84863422466
-
Overcoming disappointing results with antiangiogenic therapy by targetinghypoxia
-
Rapisarda, A., and Melillo, G. (2012). Overcoming disappointing results with antiangiogenic therapy by targetinghypoxia. Nat. Rev. Clin. Oncol. 9, 378-390.
-
(2012)
Nat. Rev. Clin. Oncol.
, vol.9
, pp. 378-390
-
-
Rapisarda, A.1
Melillo, G.2
-
63
-
-
79954470620
-
Emerging therapiesinthe treatment of locally advanced squamous cell cancers of head and neck
-
Raza, S., Kornblum, N., Kancharla,V. P., Baig, M.A., Singh,A. B., and Kalavar, M. (2011). Emerging therapiesinthe treatment of locally advanced squamous cell cancers of head and neck. Recent Pat. Anticancer Drug. Discov. 6, 246-257.
-
(2011)
Recent Pat. Anticancer Drug. Discov.
, vol.6
, pp. 246-257
-
-
Raza, S.1
Kornblum, N.2
Kancharla, V.P.3
Baig, M.A.4
Singh, A.B.5
Kalavar, M.6
-
64
-
-
84857502654
-
Erlotinib versus standard chemotherapy as firstline treatment for European patients with advanced EGFR mutationpositive non-small-cell lung cancer (EURTAC): a multicentre, openlabel, randomised phase 3 trial
-
Spanish Lung Cancer Group in collaboration with Groupe Français de Pneumo-Cancérologie and Associazione Italiana Oncologia Toracica
-
Rosell, R., Carcereny, E., Gervais, R., Vergnenegre, A., Massuti, B., Felip, E., Palmero, R., Garcia-Gomez, R., Pallares, C., Sanchez, J. M., Porta, R., Cobo, M., Garrido, P., Longo, F., Moran, T., Insa, A., De Marinis, F., Corre, R., Bover, I., Illiano, A., Dansin, E., de Castro, J., Milella, M., Reguart, N., Altavilla, G., Jimenez, U., Provencio, M., Moreno, M. A., Terrasa, J., Muñoz-Langa, J., Valdivia, J., Isla, D., Domine, M., Molinier, O., Mazieres, J., Baize, N., Garcia-Campelo, R., Robinet, G., Rodriguez-Abreu, D., Lopez-Vivanco, G., Gebbia, V., Ferrera-Delgado, L., Bombaron, P., Bernabe, R., Bearz, A., Artal, A., Cortesi, E., Rolfo, C., Sanchez-Ronco, M., Drozdowskyj, A., Queralt, C., de Aguirre, I., Ramirez, J. L., Sanchez, J. J., Molina, M. A., Taron, M., Paz-Ares, L., and Spanish Lung Cancer Group in collaboration with Groupe Français de Pneumo-Cancérologie and Associazione Italiana Oncologia Toracica. (2012). Erlotinib versus standard chemotherapy as firstline treatment for European patients with advanced EGFR mutationpositive non-small-cell lung cancer (EURTAC): a multicentre, openlabel, randomised phase 3 trial. Lancet Oncol. 13, 239-246.
-
(2012)
Lancet Oncol
, vol.13
, pp. 239-246
-
-
Rosell, R.1
Carcereny, E.2
Gervais, R.3
Vergnenegre, A.4
Massuti, B.5
Felip, E.6
Palmero, R.7
Garcia-Gomez, R.8
Pallares, C.9
Sanchez, J.M.10
Porta, R.11
Cobo, M.12
Garrido, P.13
Longo, F.14
Moran, T.15
Insa, A.16
De Marinis, F.17
Corre, R.18
Bover, I.19
Illiano, A.20
Dansin, E.21
de Castro, J.22
Milella, M.23
Reguart, N.24
Altavilla, G.25
Jimenez, U.26
Provencio, M.27
Moreno, M.A.28
Terrasa, J.29
Muñoz-Langa, J.30
Valdivia, J.31
Isla, D.32
Domine, M.33
Molinier, O.34
Mazieres, J.35
Baize, N.36
Garcia-Campelo, R.37
Robinet, G.38
Rodriguez-Abreu, D.39
Lopez-Vivanco, G.40
Gebbia, V.41
Ferrera-Delgado, L.42
Bombaron, P.43
Bernabe, R.44
Bearz, A.45
Artal, A.46
Cortesi, E.47
Rolfo, C.48
Sanchez-Ronco, M.49
Drozdowskyj, A.50
Queralt, C.51
de Aguirre, I.52
Ramirez, J.L.53
Sanchez, J.J.54
Molina, M.A.55
Taron, M.56
Paz-Ares, L.57
more..
-
65
-
-
0141919421
-
Topoisomerases and tubulin inhibitors: a promising combination for cancer treatment
-
Rudolf, E., and Cervinka, M. (2003). Topoisomerases and tubulin inhibitors: a promising combination for cancer treatment. Curr. Med. Chem. Anticancer Agents 3, 421-429.
-
(2003)
Curr. Med. Chem. Anticancer Agents
, vol.3
, pp. 421-429
-
-
Rudolf, E.1
Cervinka, M.2
-
66
-
-
84866172984
-
The tumor stroma as mediator of drug resistance - a potential target to improve cancer therapy?
-
[Epub ahead of print]
-
Sebens, S., and Schäfer, H. (2011). The tumor stroma as mediator of drug resistance - a potential target to improve cancer therapy? Curr. Pharm. Biotechnol. [Epub ahead of print]
-
(2011)
Curr. Pharm. Biotechnol.
-
-
Sebens, S.1
Schäfer, H.2
-
67
-
-
76349095132
-
Defining the role of hypoxiainducible factor 1 in cancer biology and therapeutics
-
Semenza, G. L. (2010). Defining the role of hypoxiainducible factor 1 in cancer biology and therapeutics. Oncogene 29, 625-634.
-
(2010)
Oncogene
, vol.29
, pp. 625-634
-
-
Semenza, G.L.1
-
68
-
-
84856739946
-
Hypoxiainducible factors in physiology and medicine
-
Semenza, G. L. (2012). Hypoxiainducible factors in physiology and medicine. Cell 2012 148, 399-408.
-
(2012)
Cell 2012
, vol.148
, pp. 399-408
-
-
Semenza, G.L.1
-
69
-
-
77951457576
-
Advances in the systemic treatment of head and neck cancers
-
Specenier, P., and Vermorken, J. B. (2010). Advances in the systemic treatment of head and neck cancers. Curr. Opin. Oncol. 22, 200-205.
-
(2010)
Curr. Opin. Oncol.
, vol.22
, pp. 200-205
-
-
Specenier, P.1
Vermorken, J.B.2
-
70
-
-
33750877273
-
Spindle cell carcinoma of the oral cavity and oropharynx: factors affecting outcome
-
Su, H. H., Chu, S. T., Hou, Y. Y., Chang, K. P., and Chen, C. J. (2006). Spindle cell carcinoma of the oral cavity and oropharynx: factors affecting outcome. J. Chin. Med. Assoc. 69, 478-483.
-
(2006)
J. Chin. Med. Assoc.
, vol.69
, pp. 478-483
-
-
Su, H.H.1
Chu, S.T.2
Hou, Y.Y.3
Chang, K.P.4
Chen, C.J.5
-
71
-
-
0036595629
-
Epithelialmesenchymal transitions in tumor progression
-
Thiery, J. P. (2002). Epithelialmesenchymal transitions in tumor progression. Nat. Rev. Cancer 2, 442-454.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 442-454
-
-
Thiery, J.P.1
-
72
-
-
36749028203
-
Molecular pathways and related target therapies in liver carcinoma
-
Tommasi, S., Pinto, R., Pilato, B., and Paradiso, A. (2007). Molecular pathways and related target therapies in liver carcinoma. Curr. Pharm. Des. 13, 3279-3287.
-
(2007)
Curr. Pharm. Des.
, vol.13
, pp. 3279-3287
-
-
Tommasi, S.1
Pinto, R.2
Pilato, B.3
Paradiso, A.4
-
73
-
-
35148881028
-
Drug resistance and the solid tumor microenvironment
-
Trédan, O., Galmarini, C. M., Patel, K., and Tannock,I.F.(2007). Drug resistance and the solid tumor microenvironment. J. Natl. Cancer Inst. 99, 1441-1454.
-
(2007)
J. Natl. Cancer Inst.
, vol.99
, pp. 1441-1454
-
-
Trédan, O.1
Galmarini, C.M.2
Patel, K.3
Tannock, I.F.4
-
74
-
-
84860803116
-
Targeting EGFR in Pancreatic Cancer Treatment
-
Troiani, T., Martinelli, E., Capasso, A., Morgillo, F., Orditura, M., De Vita, F., and Ciardiello, F. (2012). Targeting EGFR in Pancreatic Cancer Treatment. Curr. Drug Targets 13, 802-810.
-
(2012)
Curr. Drug Targets
, vol.13
, pp. 802-810
-
-
Troiani, T.1
Martinelli, E.2
Capasso, A.3
Morgillo, F.4
Orditura, M.5
De Vita, F.6
Ciardiello, F.7
-
75
-
-
80052242132
-
Targeting cancer metabolism: a therapeutic window opens
-
Vander Heiden, M. G. (2011). Targeting cancer metabolism: a therapeutic window opens. Nat. Rev. Drug Discov. 10, 671-684.
-
(2011)
Nat. Rev. Drug Discov.
, vol.10
, pp. 671-684
-
-
Vander Heiden, M.G.1
-
76
-
-
35548966042
-
Cisplatin, fluorouracil, and docetaxel in unresectable head and neck cancer
-
Vermorken, J. B., Remenar, E., van Herpen, C., Gorlia, T., Mesia, R., Degardin, M., Stewart, J. S., Jelic, S., Betka, J., Preiss, J. H., van den Weyngaert, D., Awada, A., Cupissol, D., Kienzer, H. R., Rey, A., Desaunois, I., Bernier, J., and Lefebvre, J. L. (2007). Cisplatin, fluorouracil, and docetaxel in unresectable head and neck cancer. N. Engl. J. Med. 357, 1695-1704.
-
(2007)
N. Engl. J. Med.
, vol.357
, pp. 1695-1704
-
-
Vermorken, J.B.1
Remenar, E.2
van Herpen, C.3
Gorlia, T.4
Mesia, R.5
Degardin, M.6
Stewart, J.S.7
Jelic, S.8
Betka, J.9
Preiss, J.H.10
van den Weyngaert, D.11
Awada, A.12
Cupissol, D.13
Kienzer, H.R.14
Rey, A.15
Desaunois, I.16
Bernier, J.17
Lefebvre, J.L.18
-
77
-
-
0031847422
-
Recurrent chromosomal imbalances detected in biopsy material from oral premalignant and malignant lesions by combined tissue microdissection, universal DNA amplification, and comparative genomic hybridization
-
Weber, R. G., Scheer, M., Born, I. A., Joos, S., Cobbers, J. M., Hofele, C., Reifenberger, G., Zöller, J. E., and Lichter, P. (1998). Recurrent chromosomal imbalances detected in biopsy material from oral premalignant and malignant lesions by combined tissue microdissection, universal DNA amplification, and comparative genomic hybridization.Am. J. Pathol. 153, 295-303.
-
(1998)
Am. J. Pathol.
, vol.153
, pp. 295-303
-
-
Weber, R.G.1
Scheer, M.2
Born, I.A.3
Joos, S.4
Cobbers, J.M.5
Hofele, C.6
Reifenberger, G.7
Zöller, J.E.8
Lichter, P.9
-
78
-
-
75849118878
-
Targeting the PI3K signaling pathway in cancer
-
Wong, K. K., Engelman,J. A., and Cantley, L. C. (2010). Targeting the PI3K signaling pathway in cancer. Curr. Opin. Genet. Dev. 20, 87-90.
-
(2010)
Curr. Opin. Genet. Dev.
, vol.20
, pp. 87-90
-
-
Wong, K.K.1
Engelman, J.A.2
Cantley, L.C.3
-
79
-
-
0033024542
-
Survival and patterns of recurrence in 200 oral cancer patients treated by radical surgery and neck dissection
-
Woolgar, J. A., Rogers, S., West, C. R., Errington, R. D., Brown, J. S., and Vaughan, E. D. (1999). Survival and patterns of recurrence in 200 oral cancer patients treated by radical surgery and neck dissection. Oral Oncol. 35, 257-265.
-
(1999)
Oral Oncol
, vol.35
, pp. 257-265
-
-
Woolgar, J.A.1
Rogers, S.2
West, C.R.3
Errington, R.D.4
Brown, J.S.5
Vaughan, E.D.6
-
80
-
-
67650996754
-
Biomarkers for epithelialmesenchymal transitions
-
Zeisberg, M., and Neilson, E. G. (2009). Biomarkers for epithelialmesenchymal transitions. J. Clin. Invest. 119, 1429-1437.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 1429-1437
-
-
Zeisberg, M.1
Neilson, E.G.2
|