The relationship of genetic aberrations detected by comparative genomic hybridization to DNA ploidy and tumor size in human oral squamous cell carcinomas

Journal of Oral Pathology and Medicine

Volumn 29, Issue 5, 2000, Pages 226-231

  Okafuji, Masaki ^a   Ita, Masamichi ^a   Oga, Atsunori ^a   Hayatsu, Yoshikazu ^a   Matsuo, Akira ^a   Shinzato, Yuichi ^b   Shinozaki, Fumihiko ^a   Sasaki, Kohsuke ^a  

^a YAMAGUCHI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Shimonoseki City Hospital   (Japan)

Author keywords

Chromosome; Comparative genomic hybridization (CGH); DNA; Genetic aberration; Laser scanning cytometer (LSC); Oral squamous cell carcinoma

Indexed keywords

ANEUPLOIDY; CARCINOMA CELL; CHROMOSOME ABERRATION; COMPARATIVE GENOMIC HYBRIDIZATION; DIPLOIDY; GENETIC GAIN; IN SITU HYBRIDIZATION; LASER SCANNING CYTOMETRY; MOUTH CARCINOMA; NUCLEOTIDE SEQUENCE; SQUAMOUS CELL CARCINOMA; TUMOR DIAGNOSIS; TUMOR VOLUME;

AGED; BIOPSY; CARCINOMA, SQUAMOUS CELL; CHROMOSOME ABERRATIONS; DNA, NEOPLASM; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MALE; MIDDLE AGED; MOUTH MUCOSA; MOUTH NEOPLASMS; NEOPLASM STAGING; NUCLEIC ACID HYBRIDIZATION; PLOIDIES;

EID: 0034052286     PISSN: 09042512     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0714.2000.290506.x     Document Type: Article

References (24)

1. Mertens F, Johansson B, Hoglund M, Mitelman F. Chromosomal imbalance maps of malignant solid tumors: a cytogenetic survey of 3185 neoplasms. Cancer Res 1997; 57: 2765-80.
2. Kallioniemi A, Kallioniemi OP, Suder D, et al. Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors. Science 1992; 258: 818-21.
3. Lengauer C, Kinzler KW, Vogelstein B. Genetic instability in colorectal cancers. Nature 1997; 386: 623-7.
4. Lengauer C, Kinzler KW, Vogelstein B. Genetic instabilities in human cancers. Nature 1998; 396: 643-9.
5. Sasaki K, Kurose A, Mimura Y, Sato T, Ikeda E. DNA ploidy analysis by laser scanning cytometry (LSC) in colorectal cancers and comparison with flow cytometry. Cytometry 1996; 23: 106-9.
6. Nishizaki T, Devris S, Chew K, Waldman FM. Genetic alterations in primary breast cancers and their metastases: direct comparison using modified comparative genomic hybridization. Genes Chromosomes Cancer 1997; 19: 267-72.
7. Nishizaki T, Chew K, Chu L, et al. Genetic alterations in lobular breast cancer by comparative genomic hybridization. Int J Cancer 1997; 74: 513-7.
8. Kamenysky LA, Kamenysky LD. Microscope-based multiparameter laser scanning cytometer yielding data comparable to flow cytometry data. Cytometry 1997; 57: 381-7.
9. Okafuji M, Ita M, Hayatsu Y, Shinozaki F, Oga A, Sasaki K. Identification of genetic aberrations in cell lines from oral squamous cell carcinomas by comparative genomic hybridization. J Oral Pathol Med 1999; 28: 241-5.
10. Komiyama T, Matsumura K, Tuchida N. Comparison of DNA copy numbers in original oral squamous cell carcinomas and corresponding cell lines by comparative genomic hybridization. Jpn J Cancer Res 1997; 88: 476-83.
11. Weber RG, Scheer M, Born IA, et al. Recurrent chromosomal imbalances detected in biopsy material from oral premalignant and malignant lesions by combined tissue microdissection, universal DNA amplification, and comparative genomic hybridization. Am J Pathol 1998, 153: 295-303.
12. Hermsen MA, Joenje H, Arwert F, et al. Assessment of chromosomal gains and losses in oral squamous cell carcinoma by comparative genomic hybridization. Oral Oncol 1997; 33: 414-8.
13. Bockmuhl U, Wolf G, Schmidt S, et al. Genomic alterations associated with malignancy in head and neck cancer. Head Neck 1998; 20: 145-51.
14. Wolff E, Girod S, Liehr T, et al. Oral squamous cell carcinomas are characterized by a rather uniform pattern of genomic imbalances detected by comparative genomic hybridization Oral Oncol 1998; 34: 186-90.
15. Zhang H, Kobayashi R, Galaktinov K, Beach D. P19skp1 and P45skp2 are essential elements of the cyclin A-CDK2 S phase kinase. Cell 1995; 82: 915-25.
16. Heselmeyer K, MacVille M, Schrock E, et al. Advanced-stage cervical carcinomas are defined by a recurrent pattern of chromosomal aberrations revealing high genetic instability and a consistent gain of chromosome arm 3q. Genes Chromosomes Cancer 1997; 19: 233-40.
17. Takes RP, Baatenburg de Jong RJ, Schuuring E, et al. Differences in expression of oncogenes and tumor suppressor genes in different sites of head and neck squamous cell. Anticancer Res 1998; 18: 4793-800.
18. Perron ER, Cho KR, Nigro JM, et al. Identification of chromosome 18q gene that is altered in colorectal cancers. Science 1990; 247: 49-56.
19. Kikuchi-Yanoshita R, Konishi M, Fukunari H, Tanaka K, Miyaki M. Loss of expression of DCC gene during progression of colorectal carcinomas in familial adenomatous polyposis patient. Cancer Res 1992; 52: 3801-3.
20. Hahn SA, Schutte M, Hoque AT, et al. DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 1996; 271: 350-3.
21. Heim S, Mitelman F. Cancer cytogenetics. New York: Liss, 1987.
22. Hartwell L. Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells. Cell 1992; 71: 543-6.
23. Harada K, Nishizaki T, Ozaki S, et al. Intratumoral cytogenetic heterogeneity detected by comparative genomic hybridization and laser scanning cytometry in human gliomas. Cancer Res 1998; 58: 4694-700.
24. Kjellman M, Kallioniemi OP, Karhu R, et al. Genetic aberrations in adrenocortical tumors detected using comparative genomic hybridization correlate with tumor size and malignancy. Cancer Res 1996; 56: 4219-23.