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Volumn 10, Issue 1, 2012, Pages

Phenotypes and clinical significance of circulating CD4+CD25+ regulatory T cells (Tregs) in patients with acute-on-chronic liver failure (ACLF)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE ON CHRONIC LIVER FAILURE; ADULT; ARTICLE; BETA CHAIN; BLOOD ANALYSIS; CD4+ CD25+ T LYMPHOCYTE; CELL SELECTION; CHRONIC HEPATITIS; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; FLOW CYTOMETRY; GENE SEQUENCE; HUMAN; LYMPHOCYTE FUNCTION; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PROTEIN MOTIF; REGULATORY T LYMPHOCYTE;

EID: 84866178515     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-10-193     Document Type: Article
Times cited : (28)

References (40)
  • 1
    • 65649098653 scopus 로고    scopus 로고
    • Patient to patient transmission of hepatitis B virus: a systematic review of reports on outbreaks between 1992 and 2007
    • 10.1186/1741-7015-7-15, 2676313, 19356228
    • Lanini S, Puro V, Lauria FN, Fusco FM, Nisii C, Ippolito G. Patient to patient transmission of hepatitis B virus: a systematic review of reports on outbreaks between 1992 and 2007. BMC Med 2009, 7:15. 10.1186/1741-7015-7-15, 2676313, 19356228.
    • (2009) BMC Med , vol.7 , pp. 15
    • Lanini, S.1    Puro, V.2    Lauria, F.N.3    Fusco, F.M.4    Nisii, C.5    Ippolito, G.6
  • 3
    • 79954420635 scopus 로고    scopus 로고
    • Association of hepatitis B virus mutations in basal core promoter and precore regions with severity of liver disease: an investigation of 793 Chinese patients with mild and severe chronic hepatitis B and acute-on-chronic liver failure
    • 10.1007/s00535-010-0315-4, 20848146
    • Xu Z, Ren X, Liu Y, Li X, Bai S, Zhong Y, Wang L, Mao P, Wang H, Xin S, Wong VW, Chan HL, Zoulim F, Xu D. Association of hepatitis B virus mutations in basal core promoter and precore regions with severity of liver disease: an investigation of 793 Chinese patients with mild and severe chronic hepatitis B and acute-on-chronic liver failure. J Gastroenterol 2011, 46:391-400. 10.1007/s00535-010-0315-4, 20848146.
    • (2011) J Gastroenterol , vol.46 , pp. 391-400
    • Xu, Z.1    Ren, X.2    Liu, Y.3    Li, X.4    Bai, S.5    Zhong, Y.6    Wang, L.7    Mao, P.8    Wang, H.9    Xin, S.10    Wong, V.W.11    Chan, H.L.12    Zoulim, F.13    Xu, D.14
  • 4
    • 0036184310 scopus 로고    scopus 로고
    • Acute-on-chronic liver failure: pathophysiological basis of therapeutic options
    • 10.1159/000047017, 11867872
    • Jalan R, Williams R. Acute-on-chronic liver failure: pathophysiological basis of therapeutic options. Blood Purif 2002, 20:252-261. 10.1159/000047017, 11867872.
    • (2002) Blood Purif , vol.20 , pp. 252-261
    • Jalan, R.1    Williams, R.2
  • 5
    • 33846817449 scopus 로고    scopus 로고
    • Long-term therapy of acute chronic liver failure to successful transplantation with an extracorporeal liver support system
    • 10.1055/s-2006-927385, 17236117
    • Jung O, Asbe-Vollkopf A, Betz C, Caspary W, Geiger H, Faust D. Long-term therapy of acute chronic liver failure to successful transplantation with an extracorporeal liver support system. Z Gastroenterol 2007, 45:21-24. 10.1055/s-2006-927385, 17236117.
    • (2007) Z Gastroenterol , vol.45 , pp. 21-24
    • Jung, O.1    Asbe-Vollkopf, A.2    Betz, C.3    Caspary, W.4    Geiger, H.5    Faust, D.6
  • 7
    • 80054740657 scopus 로고    scopus 로고
    • Acute-on-chronic liver failure before liver transplantation: impact on posttransplant outcomes
    • 10.1097/TP.0b013e31822e6eda, 21869735
    • Bahirwani R, Shaked O, Bewtra M, Forde K, Reddy KR. Acute-on-chronic liver failure before liver transplantation: impact on posttransplant outcomes. Transplantation 2011, 92:952-957. 10.1097/TP.0b013e31822e6eda, 21869735.
    • (2011) Transplantation , vol.92 , pp. 952-957
    • Bahirwani, R.1    Shaked, O.2    Bewtra, M.3    Forde, K.4    Reddy, K.R.5
  • 8
    • 16844369607 scopus 로고    scopus 로고
    • Natural regulatory T cells in infectious disease
    • Belkaid Y, Rouse BT. Natural regulatory T cells in infectious disease. Nat Immunol 2005, 6:353-360.
    • (2005) Nat Immunol , vol.6 , pp. 353-360
    • Belkaid, Y.1    Rouse, B.T.2
  • 9
    • 37149016672 scopus 로고    scopus 로고
    • Circulating CD4+ CD25+ regulatory T cells correlate with chronic hepatitis B infection
    • 10.1111/j.1365-2567.2007.02691.x, 2433275, 17764450
    • Peng G, Li S, Wu W, Sun Z, Chen Y, Chen Z. Circulating CD4+ CD25+ regulatory T cells correlate with chronic hepatitis B infection. Immunology 2008, 123:57-65. 10.1111/j.1365-2567.2007.02691.x, 2433275, 17764450.
    • (2008) Immunology , vol.123 , pp. 57-65
    • Peng, G.1    Li, S.2    Wu, W.3    Sun, Z.4    Chen, Y.5    Chen, Z.6
  • 10
    • 76449096344 scopus 로고    scopus 로고
    • Circulating CD4 + CD25high regulatory T cells and expression of PD-1 and BTLA on CD4+ T cells in patients with chronic hepatitis B virus infection
    • 10.1089/vim.2009.0061, 20121403
    • Nan XP, Zhang Y, Yu HT, Li Y, Sun RL, Wang JP, Bai XF. Circulating CD4 + CD25high regulatory T cells and expression of PD-1 and BTLA on CD4+ T cells in patients with chronic hepatitis B virus infection. Viral Immunol 2010, 23:63-70. 10.1089/vim.2009.0061, 20121403.
    • (2010) Viral Immunol , vol.23 , pp. 63-70
    • Nan, X.P.1    Zhang, Y.2    Yu, H.T.3    Li, Y.4    Sun, R.L.5    Wang, J.P.6    Bai, X.F.7
  • 11
    • 33745323050 scopus 로고    scopus 로고
    • Circulating and liver resident CD4 + CD25+ regulatory T cells actively influence the antiviral immune response and disease progression in patients with hepatitis B
    • Xu D, Fu J, Jin L, Zhang H, Zhou C, Zou Z, Zhao JM, Zhang B, Shi M, Ding X, Tang Z, Fu YX, Wang FS. Circulating and liver resident CD4 + CD25+ regulatory T cells actively influence the antiviral immune response and disease progression in patients with hepatitis B. J Immunol 2006, 177:739-747.
    • (2006) J Immunol , vol.177 , pp. 739-747
    • Xu, D.1    Fu, J.2    Jin, L.3    Zhang, H.4    Zhou, C.5    Zou, Z.6    Zhao, J.M.7    Zhang, B.8    Shi, M.9    Ding, X.10    Tang, Z.11    Fu, Y.X.12    Wang, F.S.13
  • 12
    • 78249287837 scopus 로고    scopus 로고
    • High mobility group box-1 protein inhibits regulatory T cell immune activity in liver failure in patients with chronic hepatitis B
    • Wang LW, Chen H, Gong ZJ. High mobility group box-1 protein inhibits regulatory T cell immune activity in liver failure in patients with chronic hepatitis B. Hepatobiliary Pancreat Dis Int 2010, 9:499-507.
    • (2010) Hepatobiliary Pancreat Dis Int , vol.9 , pp. 499-507
    • Wang, L.W.1    Chen, H.2    Gong, Z.J.3
  • 13
    • 79952816254 scopus 로고    scopus 로고
    • Bias in the alphabeta T-cell repertoire: implications for disease pathogenesis and vaccination
    • 10.1038/icb.2010.139, 21301479
    • Miles JJ, Douek DC, Price DA. Bias in the alphabeta T-cell repertoire: implications for disease pathogenesis and vaccination. Immunol Cell Biol 2011, 89:375-387. 10.1038/icb.2010.139, 21301479.
    • (2011) Immunol Cell Biol , vol.89 , pp. 375-387
    • Miles, J.J.1    Douek, D.C.2    Price, D.A.3
  • 15
    • 77953826461 scopus 로고    scopus 로고
    • Diagnostic and treatment guidelines for liver failure
    • Liver Failure and Artificial Liver Group Chinese Society of Infectious Diseases Chinese Medical Association; Severe Liver Diseases and Artificial Liver Group Chinese Society of Hepatology Chinese Medical Association
    • Liver Failure and Artificial Liver Group Chinese Society of Infectious Diseases Chinese Medical Association; Severe Liver Diseases and Artificial Liver Group Chinese Society of Hepatology Chinese Medical Association Diagnostic and treatment guidelines for liver failure. Zhonghua Gan Zang Bing Za Zhi 2006, 14:643-646. Liver Failure and Artificial Liver Group Chinese Society of Infectious Diseases Chinese Medical Association; Severe Liver Diseases and Artificial Liver Group Chinese Society of Hepatology Chinese Medical Association.
    • (2006) Zhonghua Gan Zang Bing Za Zhi , vol.14 , pp. 643-646
  • 17
    • 79957523611 scopus 로고    scopus 로고
    • Effect of telbivudine therapy on the cellular immune response in chronic hepatitis B
    • 10.1016/j.antiviral.2011.04.008, 21549152
    • Chen Y, Li X, Ye B, Yang X, Wu W, Chen B, Pan X, Cao H, Li L. Effect of telbivudine therapy on the cellular immune response in chronic hepatitis B. Antiviral Res 2011, 91:23-31. 10.1016/j.antiviral.2011.04.008, 21549152.
    • (2011) Antiviral Res , vol.91 , pp. 23-31
    • Chen, Y.1    Li, X.2    Ye, B.3    Yang, X.4    Wu, W.5    Chen, B.6    Pan, X.7    Cao, H.8    Li, L.9
  • 18
    • 36849033062 scopus 로고    scopus 로고
    • Cellular chromosome DNA interferes with fluorescence quantitative real-time PCR detection of HBV DNA in culture medium
    • 10.1002/jmv.21042, 18041004
    • Pan XB, Wei L, Han JC, Gao Y. Cellular chromosome DNA interferes with fluorescence quantitative real-time PCR detection of HBV DNA in culture medium. J Med Virol 2008, 80:47-52. 10.1002/jmv.21042, 18041004.
    • (2008) J Med Virol , vol.80 , pp. 47-52
    • Pan, X.B.1    Wei, L.2    Han, J.C.3    Gao, Y.4
  • 19
    • 77954364664 scopus 로고    scopus 로고
    • Rapid detection of clonal expansion of T-cell receptor-beta gene in patients with HBV using the real-time PCR with DNA melting curve analysis
    • 10.1111/j.1872-034X.2009.00600.x, 20070405
    • Yang JZ, Li MW, Wang JG, Lu HF, Yao XS, He JQ, Li LJ. Rapid detection of clonal expansion of T-cell receptor-beta gene in patients with HBV using the real-time PCR with DNA melting curve analysis. Hepatol Res 2010, 40:407-414. 10.1111/j.1872-034X.2009.00600.x, 20070405.
    • (2010) Hepatol Res , vol.40 , pp. 407-414
    • Yang, J.Z.1    Li, M.W.2    Wang, J.G.3    Lu, H.F.4    Yao, X.S.5    He, J.Q.6    Li, L.J.7
  • 20
    • 82955188803 scopus 로고    scopus 로고
    • Molecular features of the complementarity determining region 3 motif of the T cell population and subsets in the blood of patients with chronic severe hepatitis B
    • 10.1186/1479-5876-9-210, 3256121, 22152113
    • Yang J, He J, Lu H, Wei L, Li S, Wang B, Diao H, Li L. Molecular features of the complementarity determining region 3 motif of the T cell population and subsets in the blood of patients with chronic severe hepatitis B. J Transl Med 2011, 9:210. 10.1186/1479-5876-9-210, 3256121, 22152113.
    • (2011) J Transl Med , vol.9 , pp. 210
    • Yang, J.1    He, J.2    Lu, H.3    Wei, L.4    Li, S.5    Wang, B.6    Diao, H.7    Li, L.8
  • 21
    • 0035032721 scopus 로고    scopus 로고
    • A molecular comparison of T lymphocyte populations infiltrating the liver and circulating in the blood of patients with chronic hepatitis B: evidence for antigen-driven selection of a public complementarity-determining region 3 (CDR3) motif
    • 10.1053/jhep.2001.24026, 11343258
    • Sing GK, Li D, Chen X, Macnaughton T, Lichanska AM, Butterworth L, Ladhams A, Cooksley G. A molecular comparison of T lymphocyte populations infiltrating the liver and circulating in the blood of patients with chronic hepatitis B: evidence for antigen-driven selection of a public complementarity-determining region 3 (CDR3) motif. Hepatology 2001, 33:1288-1298. 10.1053/jhep.2001.24026, 11343258.
    • (2001) Hepatology , vol.33 , pp. 1288-1298
    • Sing, G.K.1    Li, D.2    Chen, X.3    Macnaughton, T.4    Lichanska, A.M.5    Butterworth, L.6    Ladhams, A.7    Cooksley, G.8
  • 22
    • 16244385911 scopus 로고    scopus 로고
    • Regulatory T cells contribute to the impaired immune response in patients with chronic hepatitis B virus infection
    • 10.1002/hep.20649, 15791617
    • Stoop JN, van der Molen RG, Baan CC, van der Laan LJ, Kuipers EJ, Kusters JG, Janssen HL. Regulatory T cells contribute to the impaired immune response in patients with chronic hepatitis B virus infection. Hepatology 2005, 41:771-778. 10.1002/hep.20649, 15791617.
    • (2005) Hepatology , vol.41 , pp. 771-778
    • Stoop, J.N.1    van der Molen, R.G.2    Baan, C.C.3    van der Laan, L.J.4    Kuipers, E.J.5    Kusters, J.G.6    Janssen, H.L.7
  • 23
    • 20644434609 scopus 로고    scopus 로고
    • Relationship of CD4 + CD25+ regulatory T cells to immune status in HIV-infected patients
    • 10.1097/01.aids.0000171401.23243.56, 15905668
    • Tsunemi S, Iwasaki T, Imado T, Higasa S, Kakishita E, Shirasaka T, Sano H. Relationship of CD4 + CD25+ regulatory T cells to immune status in HIV-infected patients. AIDS 2005, 19:879-886. 10.1097/01.aids.0000171401.23243.56, 15905668.
    • (2005) AIDS , vol.19 , pp. 879-886
    • Tsunemi, S.1    Iwasaki, T.2    Imado, T.3    Higasa, S.4    Kakishita, E.5    Shirasaka, T.6    Sano, H.7
  • 24
    • 34047266620 scopus 로고    scopus 로고
    • Inhibition of viral replication reduces regulatory T cells and enhances the antiviral immune response in chronic hepatitis B
    • 10.1016/j.virol.2006.11.018, 17184802
    • Stoop JN, van der Molen RG, Kuipers EJ, Kusters JG, Janssen HL. Inhibition of viral replication reduces regulatory T cells and enhances the antiviral immune response in chronic hepatitis B. Virology 2007, 361:141-148. 10.1016/j.virol.2006.11.018, 17184802.
    • (2007) Virology , vol.361 , pp. 141-148
    • Stoop, J.N.1    van der Molen, R.G.2    Kuipers, E.J.3    Kusters, J.G.4    Janssen, H.L.5
  • 25
    • 68349108225 scopus 로고    scopus 로고
    • Detection of clonal immunoglobulin and T-cell receptor gene recombination in hematological malignancies: monitoring minimal residual disease
    • 10.2174/187152909788488627, 19519371
    • Garcia-Castillo H, Barros-Nunez P. Detection of clonal immunoglobulin and T-cell receptor gene recombination in hematological malignancies: monitoring minimal residual disease. Cardiovasc Hematol Disord Drug Targets 2009, 9:124-135. 10.2174/187152909788488627, 19519371.
    • (2009) Cardiovasc Hematol Disord Drug Targets , vol.9 , pp. 124-135
    • Garcia-Castillo, H.1    Barros-Nunez, P.2
  • 26
    • 0030966756 scopus 로고    scopus 로고
    • Positive selection of thymocytes bearing alpha beta T cell receptors
    • 10.1016/S0952-7915(97)80144-6, 9099796
    • Marrack P, Kappler J. Positive selection of thymocytes bearing alpha beta T cell receptors. Curr Opin Immunol 1997, 9:250-255. 10.1016/S0952-7915(97)80144-6, 9099796.
    • (1997) Curr Opin Immunol , vol.9 , pp. 250-255
    • Marrack, P.1    Kappler, J.2
  • 27
    • 33748937755 scopus 로고    scopus 로고
    • Statistical analysis of CDR3 length distributions for the assessment of T and B cell repertoire biases
    • 10.1016/j.molimm.2006.06.026, 16930714
    • Miqueu P, Guillet M, Degauque N, Dore JC, Soulillou JP, Brouard S. Statistical analysis of CDR3 length distributions for the assessment of T and B cell repertoire biases. Mol Immunol 2007, 44:1057-1064. 10.1016/j.molimm.2006.06.026, 16930714.
    • (2007) Mol Immunol , vol.44 , pp. 1057-1064
    • Miqueu, P.1    Guillet, M.2    Degauque, N.3    Dore, J.C.4    Soulillou, J.P.5    Brouard, S.6
  • 29
    • 34547976869 scopus 로고    scopus 로고
    • TCR spectratyping revealed T lymphocytes associated with graft-versus-host disease after allogeneic hematopoietic stem cell transplantation
    • 10.1080/10428190701474357, 17701594
    • Du JW, Gu JY, Liu J, Cen XN, Zhang Y, Ou Y, Chu B, Zhu P. TCR spectratyping revealed T lymphocytes associated with graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. Leuk Lymphoma 2007, 48:1618-1627. 10.1080/10428190701474357, 17701594.
    • (2007) Leuk Lymphoma , vol.48 , pp. 1618-1627
    • Du, J.W.1    Gu, J.Y.2    Liu, J.3    Cen, X.N.4    Zhang, Y.5    Ou, Y.6    Chu, B.7    Zhu, P.8
  • 30
    • 77951999656 scopus 로고    scopus 로고
    • Harnessing CD8(+) regulatory T cells: therapy for type 1 diabetes?
    • 10.1016/j.immuni.2010.04.009, 20412762
    • Zaccone P, Cooke A. Harnessing CD8(+) regulatory T cells: therapy for type 1 diabetes?. Immunity 2010, 32:504-506. 10.1016/j.immuni.2010.04.009, 20412762.
    • (2010) Immunity , vol.32 , pp. 504-506
    • Zaccone, P.1    Cooke, A.2
  • 31
    • 77953410068 scopus 로고    scopus 로고
    • Harnessing regulatory T cells for the therapy of lupus and other autoimmune diseases
    • 10.2217/imt.09.2, 20635958
    • Sharabi A, Mozes E. Harnessing regulatory T cells for the therapy of lupus and other autoimmune diseases. Immunotherapy 2009, 1:385-401. 10.2217/imt.09.2, 20635958.
    • (2009) Immunotherapy , vol.1 , pp. 385-401
    • Sharabi, A.1    Mozes, E.2
  • 32
    • 78650410673 scopus 로고    scopus 로고
    • Development of human anti-murine T-cell receptor antibodies in both responding and nonresponding patients enrolled in TCR gene therapy trials
    • 10.1158/1078-0432.CCR-10-1280, 3058233, 21138872
    • Davis JL, Theoret MR, Zheng Z, Lamers CH, Rosenberg SA, Morgan RA. Development of human anti-murine T-cell receptor antibodies in both responding and nonresponding patients enrolled in TCR gene therapy trials. Clin Cancer Res 2010, 16:5852-5861. 10.1158/1078-0432.CCR-10-1280, 3058233, 21138872.
    • (2010) Clin Cancer Res , vol.16 , pp. 5852-5861
    • Davis, J.L.1    Theoret, M.R.2    Zheng, Z.3    Lamers, C.H.4    Rosenberg, S.A.5    Morgan, R.A.6
  • 34
    • 65249096622 scopus 로고    scopus 로고
    • Preclinical development of T cell receptor gene therapy
    • 10.1016/j.coi.2009.02.007, 19321326
    • Bendle GM, Haanen JB, Schumacher TN. Preclinical development of T cell receptor gene therapy. Curr Opin Immunol 2009, 21:209-214. 10.1016/j.coi.2009.02.007, 19321326.
    • (2009) Curr Opin Immunol , vol.21 , pp. 209-214
    • Bendle, G.M.1    Haanen, J.B.2    Schumacher, T.N.3
  • 35
    • 79952317511 scopus 로고    scopus 로고
    • Development of a genetically-modified novel T-cell receptor for adoptive cell transfer against renal cell carcinoma
    • 10.1016/j.jim.2011.01.002, 3061346, 21255579
    • Wang QJ, Hanada K, Feldman SA, Zhao Y, Inozume T, Yang JC. Development of a genetically-modified novel T-cell receptor for adoptive cell transfer against renal cell carcinoma. J Immunol Methods 2011, 366:43-51. 10.1016/j.jim.2011.01.002, 3061346, 21255579.
    • (2011) J Immunol Methods , vol.366 , pp. 43-51
    • Wang, Q.J.1    Hanada, K.2    Feldman, S.A.3    Zhao, Y.4    Inozume, T.5    Yang, J.C.6
  • 36
    • 77953457564 scopus 로고    scopus 로고
    • Both CD4 and CD8 T cells mediate equally effective in vivo tumor treatment when engineered with a highly avid TCR targeting tyrosinase
    • 10.4049/jimmunol.1000189, 20427771
    • Frankel TL, Burns WR, Peng PD, Yu Z, Chinnasamy D, Wargo JA, Zheng Z, Restifo NP, Rosenberg SA, Morgan RA. Both CD4 and CD8 T cells mediate equally effective in vivo tumor treatment when engineered with a highly avid TCR targeting tyrosinase. J Immunol 2010, 184:5988-5998. 10.4049/jimmunol.1000189, 20427771.
    • (2010) J Immunol , vol.184 , pp. 5988-5998
    • Frankel, T.L.1    Burns, W.R.2    Peng, P.D.3    Yu, Z.4    Chinnasamy, D.5    Wargo, J.A.6    Zheng, Z.7    Restifo, N.P.8    Rosenberg, S.A.9    Morgan, R.A.10
  • 38
    • 79958840661 scopus 로고    scopus 로고
    • Engineering virus-specific T cells that target HBV infected hepatocytes and hepatocellular carcinoma cell lines
    • 10.1016/j.jhep.2010.10.025, 21145860
    • Gehring AJ, Xue SA, Ho ZZ, Teoh D, Ruedl C, Chia A, Koh S, Lim SG, Maini MK, Stauss H, Bertoletti A. Engineering virus-specific T cells that target HBV infected hepatocytes and hepatocellular carcinoma cell lines. J Hepatol 2011, 55:103-110. 10.1016/j.jhep.2010.10.025, 21145860.
    • (2011) J Hepatol , vol.55 , pp. 103-110
    • Gehring, A.J.1    Xue, S.A.2    Ho, Z.Z.3    Teoh, D.4    Ruedl, C.5    Chia, A.6    Koh, S.7    Lim, S.G.8    Maini, M.K.9    Stauss, H.10    Bertoletti, A.11
  • 39
    • 79955618397 scopus 로고    scopus 로고
    • T-cell receptor specificity of CD8(+) tregs in allotransplantation
    • 10.2217/imt.11.37, 21524168
    • Picarda E, Anegon I, Guillonneau C. T-cell receptor specificity of CD8(+) tregs in allotransplantation. Immunotherapy 2011, 3:35-37. 10.2217/imt.11.37, 21524168.
    • (2011) Immunotherapy , vol.3 , pp. 35-37
    • Picarda, E.1    Anegon, I.2    Guillonneau, C.3
  • 40
    • 73949118500 scopus 로고    scopus 로고
    • CD4(+) CD25(+) Foxp3(+) T regulatory cells with limited TCR diversity in control of autoimmunity
    • 10.4049/jimmunol.0902379, 2949410, 19949075
    • Adeegbe D, Matsutani T, Yang J, Altman NH, Malek TR. CD4(+) CD25(+) Foxp3(+) T regulatory cells with limited TCR diversity in control of autoimmunity. J Immunol 2010, 184:56-66. 10.4049/jimmunol.0902379, 2949410, 19949075.
    • (2010) J Immunol , vol.184 , pp. 56-66
    • Adeegbe, D.1    Matsutani, T.2    Yang, J.3    Altman, N.H.4    Malek, T.R.5


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