CD28-B7 interaction modulates short- and long-lived plasma cell function

Journal of Immunology

Volumn 189, Issue 6, 2012, Pages 2758-2767

  Njau, Modesta N ^a   Kim, Jin Hyang ^a   Chappell, Craig P ^a   Ravindran, Rajesh ^a   Thomas, Leela ^a   Pulendran, Bali ^a   Jacob, Joshy ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD28 ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CELL FUNCTION; CELL PROLIFERATION; CELL SELECTION; CELL SURVIVAL; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; HEMAGGLUTINATION; INFLUENZA; LYMPHOID TISSUE; MOUSE; NONHUMAN; PLASMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; SEQUENCE HOMOLOGY; T LYMPHOCYTE; UPREGULATION; VIRUS NEUTRALIZATION;

ANIMALS; ANTIGENS, CD28; B7 ANTIGENS; BONE MARROW CELLS; CELL AGING; CELL LINE; CELL SURVIVAL; FEMALE; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; PLASMA CELLS; SPLEEN; TIME FACTORS;

EID: 84866156181     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1102728     Document Type: Article

References (55)

1. Shapiro-Shelef, M., and K. Calame. 2005. Regulation of plasma-cell development. Nat. Rev. Immunol. 5: 230-242. (Pubitemid 40364824)
2. McHeyzer-Williams, L. J., and M. G. McHeyzer-Williams. 2005. Antigen-specific memory B cell development. Annu. Rev. Immunol. 23: 487-513. (Pubitemid 40563178)
3. Jacob, J., G. Kelsoe, K. Rajewsky, and U. Weiss. 1991. Intraclonal generation of antibody mutants in germinal centres. Nature 354: 389-392. (Pubitemid 21896846)
4. Good-Jacobson, K. L., and M. J. Shlomchik. 2010. Plasticity and heterogeneity in the generation of memory B cells and long-lived plasma cells: the influence of germinal center interactions and dynamics. J. Immunol. 185: 3117-3125.
5. Dogan, I., B. Bertocci, V. Vilmont, F. Delbos, J. Mégret, S. Storck, C. A. Reynaud, and J. C. Weill. 2009. Multiple layers of B cell memory with different effector functions. Nat. Immunol. 10: 1292-1299.
6. Lenschow, D. J., T. L. Walunas, and J. A. Bluestone. 1996. CD28/B7 system of T cell costimulation. Annu. Rev. Immunol. 14: 233-258. (Pubitemid 26130184)
7. Sharpe, A. H. 2009. Mechanisms of costimulation. Immunol. Rev. 229: 5-11.
8. Thompson, C. B., T. Lindsten, J. A. Ledbetter, S. L. Kunkel, H. A. Young, S. G. Emerson, J. M. Leiden, and C. H. June. 1989. CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines. Proc. Natl. Acad. Sci. USA 86: 1333-1337. (Pubitemid 19061540)
9. Lucas, P. J., I. Negishi, K. Nakayama, L. E. Fields, and D. Y. Loh. 1995. Naive CD28-deficient T cells can initiate but not sustain an in vitro antigen-specific immune response. J. Immunol. 154: 5757-5768.
10. Shahinian, A., K. Pfeffer, K. P. Lee, T. M. Kündig, K. Kishihara, A. Wakeham, K. Kawai, P. S. Ohashi, C. B. Thompson, and T. W. Mak. 1993. Differential T cell costimulatory requirements in CD28-deficient mice. Science 261: 609-612. (Pubitemid 23278372)
11. Sperling, A. I., J. A. Auger, B. D. Ehst, I. C. Rulifson, C. B. Thompson, and J. A. Bluestone. 1996. CD28/B7 interactions deliver a unique signal to naive T cells that regulates cell survival but not early proliferation. J. Immunol. 157: 3909-3917. (Pubitemid 126449299)
12. L. Immunity 3: 87-98.
13. Ferguson, S. E., S. Han, G. Kelsoe, and C. B. Thompson. 1996. CD28 is required for germinal center formation. J. Immunol. 156: 4576-4581. (Pubitemid 26174436)
14. Borriello, F., M. P. Sethna, S. D. Boyd, A. N. Schweitzer, E. A. Tivol, D. Jacoby, T. B. Strom, E. M. Simpson, G. J. Freeman, and A. H. Sharpe. 1997. B7-1 and B7-2 have overlapping, critical roles in immunoglobulin class switching and germinal center formation. Immunity 6: 303-313. (Pubitemid 27148597)
15. Kozbor, D., A. Moretta, H. A. Messner, L. Moretta, and C. M. Croce. 1987. Tp44 molecules involved in antigen-independent T cell activation are expressed on human plasma cells. J. Immunol. 138: 4128-4132. (Pubitemid 17090376)
16. Delogu, A., A. Schebesta, Q. Sun, K. Aschenbrenner, T. Perlot, and M. Busslinger. 2006. Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells. Immunity 24: 269-281.
17. Pellat-Deceunynck, C., R. Bataille, N. Robillard, J. L. Harousseau, M. J. Rapp, N. Juge-Morineau, J. Wijdenes, and M. Amiot. 1994. Expression of CD28 and CD40 in human myeloma cells: a comparative study with normal plasma cells. Blood 84: 2597-2603. (Pubitemid 24317392)
18. Robillard, N., G. Jego, C. Pellat-Deceunynck, D. Pineau, D. Puthier, M. P. Mellerin, S. Barillé, M. J. Rapp, J. L. Harousseau, M. Amiot, and R. Bataille. 1998. CD28, a marker associated with tumoral expansion in multiple myeloma. Clin. Cancer Res. 4: 1521-1526. (Pubitemid 28265238)
19. Bahlis, N. J., A. M. King, D. Kolonias, L. M. Carlson, H. Y. Liu, M. A. Hussein, H. R. Terebelo, G. E. Byrne, Jr., B. L. Levine, L. H. Boise, and K. P. Lee. 2007. CD28-mediated regulation of multiple myeloma cell proliferation and survival. Blood 109: 5002-5010. (Pubitemid 46827800)
20. Nair, J. R., L. M. Carlson, C. Koorella, C. H. Rozanski, G. E. Byrne, P. L. Bergsagel, J. P. Shaughnessy, Jr., L. H. Boise, A. Chanan-Khan, and K. P. Lee. 2011. CD28 expressed on malignant plasma cells induces a prosurvival and immunosuppressive microenvironment. J. Immunol. 187: 1243-1253.
21. Rozanski, C. H., R. Arens, L. M. Carlson, J. Nair, L. H. Boise, A. A. Chanan-Khan, S. P. Schoenberger, and K. P. Lee. 2011. Sustained antibody responses depend on CD28 function in bone marrow-resident plasma cells. J. Exp. Med. 208: 1435-1446.
22. Kim, J. H., I. Skountzou, R. Compans, and J. Jacob. 2009. Original antigenic sin responses to influenza viruses. J. Immunol. 183: 3294-3301.
23. Chappell, C. P., and J. Jacob. 2006. Identification of memory B cells using a novel transgenic mouse model. J. Immunol. 176: 4706-4715.
24. Mond, J. J., A. Lees, and C. M. Snapper. 1995. T cell-independent antigens type 2. Annu. Rev. Immunol. 13: 655-692.
25. O'Connor, B. P., V. S. Raman, L. D. Erickson, W. J. Cook, L. K. Weaver, C. Ahonen, L. L. Lin, G. T. Mantchev, R. J. Bram, and R. J. Noelle. 2004. BCMA is essential for the survival of long-lived bone marrow plasma cells. J. Exp. Med. 199: 91-98.
26. Mackay, F., and J. L. Browning. 2002. BAFF: a fundamental survival factor for B cells. Nat. Rev. Immunol. 2: 465-475. (Pubitemid 37328738)
27. Liu, J., A. Hamrouni, D. Wolowiec, V. Coiteux, K. Kuliczkowski, D. Hetuin, A. Saudemont, and B. Quesnel. 2007. Plasma cells from multiple myeloma patients express B7-H1 (PD-L1) and increase expression after stimulation with IFN-γ and TLR ligands via a MyD88-, TRAF6-, and MEK-dependent pathway. Blood 110: 296-304. (Pubitemid 47026847)
28. Marsters, S. A., M. Yan, R. M. Pitti, P. E. Haas, V. M. Dixit, and A. Ashkenazi. 2000. Interaction of the TNF homologues BLyS and APRIL with the TNF receptor homologues BCMA and TACI. Curr. Biol. 10: 785-788. (Pubitemid 30466942)
29. Minges Wols, H. A., G. H. Underhill, G. S. Kansas, and P. L. Witte. 2002. The role of bone marrow-derived stromal cells in the maintenance of plasma cell longevity. J. Immunol. 169: 4213-4221. (Pubitemid 35178192)
30. Cassese, G., S. Arce, A. E. Hauser, K. Lehnert, B. Moewes, M. Mostarac, G. Muehlinghaus, M. Szyska, A. Radbruch, and R. A. Manz. 2003. Plasma cell survival is mediated by synergistic effects of cytokines and adhesion-dependent signals. J. Immunol. 171: 1684-1690. (Pubitemid 36966450)
31. Rousset, F., E. Garcia, T. Defrance, C. Péronne, N. Vezzio, D. H. Hsu, R. Kastelein, K. W. Moore, and J. Banchereau. 1992. Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes. Proc. Natl. Acad. Sci. USA 89: 1890-1893.
32. Defrance, T., B. Vanbervliet, F. Brière, I. Durand, F. Rousset, and J. Banchereau. 1992. Interleukin 10 and transforming growth factor b cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A. J. Exp. Med. 175: 671-682.
33. Gass, J. N., N. M. Gifford, and J. W. Brewer. 2002. Activation of an unfolded protein response during differentiation of antibody-secreting B cells. J. Biol. Chem. 277: 49047-49054. (Pubitemid 35470877)
34. van Anken, E., E. P. Romijn, C. Maggioni, A. Mezghrani, R. Sitia, I. Braakman, and A. J. Heck. 2003. Sequential waves of functionally related proteins are expressed when B cells prepare for antibody secretion. Immunity 18: 243-253. (Pubitemid 36262999)
35. Auner, H. W., C. Beham-Schmid, N. Dillon, and P. Sabbattini. 2010. The life span of short-lived plasma cells is partly determined by a block on activation of apoptotic caspases acting in combination with endoplasmic reticulum stress. Blood 116: 3445-3455.
36. Greenwald, R. J., G. J. Freeman, and A. H. Sharpe. 2005. The B7 family revisited. Annu. Rev. Immunol. 23: 515-548. (Pubitemid 40563179)
37. Rulifson, I. C., A. I. Sperling, P. E. Fields, F. W. Fitch, and J. A. Bluestone. 1997. CD28 costimulation promotes the production of Th2 cytokines. J. Immunol. 158: 658-665. (Pubitemid 127492643)
38. Schweitzer, A. N., and A. H. Sharpe. 1998. Studies using antigen-presenting cells lacking expression of both B7-1 (CD80) and B7-2 (CD86) show distinct requirements for B7 molecules during priming versus restimulation of Th2 but not Th1 cytokine production. J. Immunol. 161: 2762-2771. (Pubitemid 28425695)
39. Ndejembi, M. P., J. R. Teijaro, D. S. Patke, A. W. Bingaman, M. R. Chandok, A. Azimzadeh, S. G. Nadler, and D. L. Farber. 2006. Control of memory CD4 T cell recall by the CD28/B7 costimulatory pathway. J. Immunol. 177: 7698-7706. (Pubitemid 44846285)
40. Garidou, L., S. Heydari, P. Truong, D. G. Brooks, and D. B. McGavern. 2009. Therapeutic memory T cells require costimulation for effective clearance of a persistent viral infection. J. Virol. 83: 8905-8915.
41. Borowski, A. B., A. C. Boesteanu, Y. M. Mueller, C. Carafides, D. J. Topham, J. D. Altman, S. R. Jennings, and P. D. Katsikis. 2007. Memory CD8+ T cells require CD28 costimulation. J. Immunol. 179: 6494-6503.
42. + regulatory T cells. Novartis Found. Symp. 252: 55-63; discussion 63-66, 106-114.
43. + immunoregulatory T cells that control autoimmune diabetes. Immunity 12: 431-440.
44. Sakaguchi, S. 2000. Regulatory T cells: key controllers of immunologic self-tolerance. Cell 101: 455-458.
45. + regulatory T cells in autoimmunity and allergy. Curr. Opin. Immunol. 14: 771-778.
46. + regulatory T cells. J. Immunol. 175: 4180-4183.
47. + regulatory T cells control humoral autoimmunity by suppressing the development of long-lived plasma cells. J. Immunol. 186: 1546-1553.
48. Qiu, Y. H., Z. W. Sun, Q. Shi, C. H. Su, Y. J. Chen, Y. J. Shi, R. Tao, Y. Ge, and X. G. Zhang. 2005. Apoptosis of multiple myeloma cells induced by agonist monoclonal antibody against human CD28. Cell. Immunol. 236: 154-160. (Pubitemid 41781860)
49. Magistrelli, G., P. Jeannin, G. Elson, J. F. Gauchat, T. N. Nguyen, J. Y. Bonnefoy, and Y. Delneste. 1999. Identification of three alternatively spliced variants of human CD28 mRNA. Biochem. Biophys. Res. Commun. 259: 34-37. (Pubitemid 29263989)
50. Magistrelli, G., P. Jeannin, N. Herbault, A. Benoit De Coignac, J. F. Gauchat, J. Y. Bonnefoy, and Y. Delneste. 1999. A soluble form of CTLA-4 generated by alternative splicing is expressed by nonstimulated human T cells. Eur. J. Immunol. 29: 3596-3602. (Pubitemid 29527807)
51. Oaks, M. K., and K. M. Hallett. 2000. Cutting edge: a soluble form of CTLA-4 in patients with autoimmune thyroid disease. J. Immunol. 164: 5015-5018. (Pubitemid 30305171)
52. Jeannin, P., G. Magistrelli, J. P. Aubry, G. Caron, J. F. Gauchat, T. Renno, N. Herbault, L. Goetsch, A. Blaecke, P. Y. Dietrich, et al. 2000. Soluble CD86 is a costimulatory molecule for human T lymphocytes. Immunity 13: 303-312.
53. Hebbar, M., P. Jeannin, G. Magistrelli, P. Y. Hatron, E. Hachulla, B. Devulder, J. Y. Bonnefoy, and Y. Delneste. 2004. Detection of circulating soluble CD28 in patients with systemic lupus erythematosus, primary Sjögren's syndrome and systemic sclerosis. Clin. Exp. Immunol. 136: 388-392. (Pubitemid 38543461)
54. Wong, C. K., L. C. Lit, L. S. Tam, E. K. Li, and C. W. Lam. 2005. Aberrant production of soluble costimulatory molecules CTLA-4, CD28, CD80 and CD86 in patients with systemic lupus erythematosus. Rheumatology (Oxford) 44: 989-994. (Pubitemid 41487170)
55. Hock, B. D., J. L. O'Donnell, K. Taylor, A. Steinkasserer, J. L. McKenzie, A. G. Rothwell, and K. L. Summers. 2006. Levels of the soluble forms of CD80, CD86, and CD83 are elevated in the synovial fluid of rheumatoid arthritis patients. Tissue Antigens 67: 57-60. (Pubitemid 43381216)