Soluble CD86 is a costimulatory molecule for human T lymphocytes

Immunity

Volumn 13, Issue 3, 2000, Pages 303-312

  Jeannin, Pascale ^a   Magistrelli, Giovanni ^a   Aubry, Jean Pierre ^a   Caron, Gersende ^a   Gauchat, Jean François ^a   Renno, Toufic ^a   Herbault, Nathalie ^a   Goetsch, Liliane ^a   Blaecke, Aline ^a   Dietrich, Pierre Yves ^b   Bonnefoy, Jean Yves ^a   Delneste, Yves ^a  

^a INSTITUT DE RECHERCHE PIERRE FABRE   (France)

^b GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CD86 ANTIGEN;

ANTIGEN PRESENTING CELL; ARTICLE; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; IMMUNOSURVEILLANCE; LYMPHOCYTE ACTIVATION; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0033662323     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)00030-3     Document Type: Article

References (57)

1. B70 antigen is a second ligand for CTLA-4 and CD28
2. Immunoglobulin fold characteristics of B7-1 (CD80) and B7-2 (CD86)
3. The minimum peptide epitope from the influenza virus matrix protein. Extra and intracellular loading of HLA-A2
4. Differential expression of alternate mB7-2 transcripts
5. B70/B7-2 is identical to CD86 and is the major functional ligand for CD28 expressed on human dendritic cells
6. Co-stimulation in T cell responses
7. Activation of naive, memory and effector T cells
8. Response of naive antigen-specific CD4+ T cells in vitro: Characteristics and antigen-presenting cell requirements
9. Primary porcine endothelial cells express membrane-bound B7-2 (CD86) and a soluble factor that co-stimulate cyclosporin A-resistant and CD28-dependent human T cell proliferation
10. B7-H1, a third member of the B7 family, co-stimulates T cell proliferation and interleukin-10 secretion
11. The B7-2(B70) costimulatory molecule expressed by monocytes and activated B lymphocytes is the CD86 differentiation antigen
12. Differential expression and function of CD80 (B7-1) and CD86 (B7-2) on human peripheral blood monocytes
13. Cloning of B7-2: A CTLA-4 counter-receptor that costimulates human T cell proliferation
14. B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4
15. CD28/B7 costimulation: A review
16. CTLA-4 mediates antigen-specific apoptosis of human T cells
17. Mutational analysis of an alternatively spliced product of B7 defines its CD28/CTLA4-binding site on immunoglobulin C-like domain
18. Expression and co-stimulatory function of B7-2 on murine CD4+ T cells
19. CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones
20. Comparative analysis of B7-1 and B7-2 costimulatory ligands: Expression and function
21. ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28
22. Structure and dimerization of a soluble form of B7.1
23. Identification of an alternatively spliced form of the murine homologue of B7
24. The role of the B7-1a molecule, an alternatively spliced form of murine B7-1 (CD80), on T cell activation
25. Thiols decrease human interleukin (IL) 4 production and IL-4-induced immunoglobulin synthesis
26. Human effector memory T cells express CD86: A functional role in naive T cell priming
27. Genomic organization of the gene coding for the costimulatory human B-lymphocyte antigen B7-2 (CD86)
28. B7-CD28/CTLA-4 costimulatory pathways are required for the development of T helper cell 2-mediated allergic airway responses to inhaled antigens
29. Two distinct regions of the CD28 intracytoplasmic domain are involved in the tyrosine phosphorylation of Vav and GTPase activating protein-associated p62 protein
30. CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation
31. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy
32. + memory T cells
33. CD28/B7 system of T cell costimulation
34. T cell antigen CD28 mediates adhesion with B cells by interacting with activation antigen B7/B-1
35. Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation
36. CTLA-4 is a second receptor for the B cell activation antigen B7
37. Immunosuppression in vivo by a soluble form of the CTLA-4 T cell activation molecule
38. Binding stoichiometry of the cytotoxic T lymphocyte-associated molecule-4 (CTLA-4). A disulfide-linked homodimer binds two CD86 molecules
39. Cells that present both specific ligand and costimulatory activity are the most efficient inducers of clonal expansion of normal CD4 T cells
40. Qualitative and quantitative effects of CD28/B7-mediated costimulation on naive T cells in vitro
41. B7-1 is superior to B7-2 costimulation in the induction and maintenance of T cell-mediated antileukemia immunity. Further evidence that B7-1 and B7-2 are functionally distinct
42. Activation of human peripheral blood dendritic cells induces the CD86 co-stimulatory molecule
43. A catalogue of splice junction sequences
44. The IgV domain of human B7-2(CD86) is sufficient to co-stimulate T lymphocytes and induce cytokine secretion
45. Negative regulation of T cell activation
46. Differential T cell costimulatory requirements in CD28-deficient mice
47. B7h, a novel costimulatory homolog of B7.1 and B7.2, is induced by TNFα
48. Expression and function of B7 on human epidermal Langerhans cells
49. CD45RO+ memory T cells but not CD45RA+ naive T cells can be efficiently activated by remote co-stimulation with B7
50. Localization in situ of the co-stimulatory molecules B7.1, B7.2, CD40 and their ligands in normal human lymphoid tissue
51. Efficient and rapid affinity purification of proteins using recombinant fusion proteases
52. CTLA-4 can function as a negative regulator of T cell activation
53. Differential requirements for co-stimulatory signals from B7 family members by resting versus recently activated memory T cells towards soluble recall antigens
54. B lymphoblast antigen (BB-1) expressed on Epstein-Barr virus-activated B cell blasts, B lymphoblastoid cell lines, and Burkitt's lymphomas
55. Functional CD86 (B7-2/B70) on cultured human Langerhans cells
56. T-cell co-stimulation through B7RP-1 and ICOS
57. On immunological memory