메뉴 건너뛰기




Volumn 86, Issue 18, 2012, Pages 9952-9963

Peripheral blood CD4 T-cell and plasmacytoid dendritic cell (pDC) reactivity to herpes simplex virus 2 and pDC number do not correlate with the clinical or virologic severity of recurrent genital herpes

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CD4+ T LYMPHOCYTE; CELL COUNT; CELL FUNCTION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; GENITAL HERPES; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; IMMUNOREACTIVITY; INFECTION CONTROL; MAJOR CLINICAL STUDY; MALE; MIXED INFECTION; PLASMACYTOID DENDRITIC CELL; PRIORITY JOURNAL; RECURRENT INFECTION; VIRUS SHEDDING;

EID: 84866152540     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00829-12     Document Type: Article
Times cited : (26)

References (69)
  • 1
    • 33846927030 scopus 로고    scopus 로고
    • Selective defect in plasmacyoid dendritic cell function in a patient with AIDS-associated atypical genital herpes simplex vegetans treated with imiquimod
    • Abbo L, et al. 2007. Selective defect in plasmacyoid dendritic cell function in a patient with AIDS-associated atypical genital herpes simplex vegetans treated with imiquimod. Clin. Infect. Dis. 44:e25-e27.
    • (2007) Clin. Infect. Dis , vol.44
    • Abbo, L.1
  • 2
    • 0034116706 scopus 로고    scopus 로고
    • Frequencies of memory T cells specific for varicella-zoster virus, herpes simplex virus and cytomegalovirus determined by intracellular detection of cytokine expression
    • Asanuma H, Sharp M, Maecker HT, Maino VC, Arvin AM. 2000. Frequencies of memory T cells specific for varicella-zoster virus, herpes simplex virus and cytomegalovirus determined by intracellular detection of cytokine expression. J. Infect. Dis. 181:859-866.
    • (2000) J. Infect. Dis , vol.181 , pp. 859-866
    • Asanuma, H.1    Sharp, M.2    Maecker, H.T.3    Maino, V.C.4    Arvin, A.M.5
  • 3
    • 0023837735 scopus 로고    scopus 로고
    • Comparison of Western blot (immunoblot) and glycoprotein G-specific immunodot enzyme assay for detecting antibodies to herpes simplex virus types 1 and 2 in human sera
    • Ashley RL, Militoni J, Lee F, Nahmias A, Corey L. 1988. Comparison of Western blot (immunoblot) and glycoprotein G-specific immunodot enzyme assay for detecting antibodies to herpes simplex virus types 1 and 2 in human sera. J. Clin. Microbiol. 26:662-667.
    • (1998) J. Clin. Microbiol , vol.26 , pp. 662-667
    • Ashley, R.L.1    Militoni, J.2    Lee, F.3    Nahmias, A.4    Corey, L.5
  • 4
    • 84855732705 scopus 로고    scopus 로고
    • Efficacy results of a trial of a herpes simplex vaccine
    • Belshe RB, et al. 2012. Efficacy results of a trial of a herpes simplex vaccine. N. Engl. J. Med. 366:34-43.
    • (2012) N. Engl. J. Med , vol.366 , pp. 34-43
    • Belshe, R.B.1
  • 5
    • 34547622158 scopus 로고    scopus 로고
    • Polymorphisms in TLR2 are associated with increased viral shedding and lesional rate in patients with genital herpes simplex virus type 2 infection
    • Bochud PY, Magaret AS, Koelle DM, Aderem A, Wald A. 2007. Polymorphisms in TLR2 are associated with increased viral shedding and lesional rate in patients with genital herpes simplex virus type 2 infection. J. Infect. Dis. 196:505-509.
    • (2007) J. Infect. Dis , vol.196 , pp. 505-509
    • Bochud, P.Y.1    Magaret, A.S.2    Koelle, D.M.3    Aderem, A.4    Wald, A.5
  • 6
    • 0026553529 scopus 로고
    • Diminished interferon-gamma and lymphocyte proliferation in neonatal and postpartum primary herpes simplex virus infection
    • Burchett SK, et al. 1992. Diminished interferon-gamma and lymphocyte proliferation in neonatal and postpartum primary herpes simplex virus infection. J. Infect. Dis. 165:813-818.
    • (1992) J. Infect. Dis , vol.165 , pp. 813-818
    • Burchett, S.K.1
  • 7
    • 33845875194 scopus 로고    scopus 로고
    • Acquisition of direct antiviral effector functions by CMV-specific CD4+ T lymphocytes with cellular maturation
    • Casazza JP, et al. 2006. Acquisition of direct antiviral effector functions by CMV-specific CD4+ T lymphocytes with cellular maturation. J. Exp. Med. 203:2865-2877.
    • (2006) J. Exp. Med , vol.203 , pp. 2865-2877
    • Casazza, J.P.1
  • 8
    • 56449115358 scopus 로고    scopus 로고
    • Asymptomatic human CD4+ cytotoxic T-cell epitopes identified from herpes simplex virus glycoprotein B
    • Chentoufi AA, et al. 2008. Asymptomatic human CD4+ cytotoxic T-cell epitopes identified from herpes simplex virus glycoprotein B. J. Virol. 82:11792-11802.
    • (2008) J. Virol , vol.82 , pp. 11792-11802
    • Chentoufi, A.A.1
  • 9
    • 0018133887 scopus 로고
    • Cellular immune response in genital herpes simplex virus infection
    • Corey L, Reeves WC, Holmes KK. 1978. Cellular immune response in genital herpes simplex virus infection. N. Engl. J. Med. 299:986-991.
    • (1978) N. Engl. J. Med , vol.299 , pp. 986-991
    • Corey, L.1    Reeves, W.C.2    Holmes, K.K.3
  • 10
    • 54049117470 scopus 로고    scopus 로고
    • Genital herpes
    • Holmes KK, et al. (ed), Sexually transmitted diseases. McGraw Hill Medical, New York, NY
    • Corey L, Wald A. 2008. Genital herpes, p 399-437. In Holmes KK, et al. (ed), Sexually transmitted diseases. McGraw Hill Medical, New York, NY.
    • Corey, L.1    Wald, A.2
  • 11
    • 0020541788 scopus 로고
    • Gamma interferon production appears to predict time of recurrence of herpes labialis
    • Cunningham AL, Merigan TC. 1983. Gamma interferon production appears to predict time of recurrence of herpes labialis. J. Immunol. 130: 2397-2400.
    • (1983) J. Immunol , vol.130 , pp. 2397-2400
    • Cunningham, A.L.1    Merigan, T.C.2
  • 12
    • 68149148869 scopus 로고    scopus 로고
    • Biomarkers of human immunosenescence: impact of cytomegalovirus infection
    • Derhovanessian E, Larbi A, Pawelec G. 2009. Biomarkers of human immunosenescence: impact of cytomegalovirus infection. Curr. Opin. Immunol. 21:440-445.
    • (2009) Curr. Opin. Immunol , vol.21 , pp. 440-445
    • Derhovanessian, E.1    Larbi, A.2    Pawelec, G.3
  • 13
    • 0003597030 scopus 로고    scopus 로고
    • Analysis of longitudinal data
    • Oxford University Press, Oxford, United Kingdom
    • Diggle PJ, Heagerty PJ, Liang KY, Zeger SL. 2002. Analysis of longitudinal data. Oxford University Press, Oxford, United Kingdom.
    • (2002)
    • Diggle, P.J.1    Heagerty, P.J.2    Liang, K.Y.3    Zeger, S.L.4
  • 14
    • 59649105482 scopus 로고    scopus 로고
    • Role for plasmacytoid dendritic cells in the immune control of recurrent human herpes simplex virus infection
    • Donaghy H, et al. 2009. Role for plasmacytoid dendritic cells in the immune control of recurrent human herpes simplex virus infection. J. Virol. 83:1952-1961.
    • (2009) J. Virol , vol.83 , pp. 1952-1961
    • Donaghy, H.1
  • 15
    • 0028048889 scopus 로고
    • Viral induction of low frequency interferonalpha producing cells
    • Feldman SB, et al. 1994. Viral induction of low frequency interferonalpha producing cells. Virology 204:1-7.
    • (1994) Virology , vol.204 , pp. 1-7
    • Feldman, S.B.1
  • 16
    • 65249134069 scopus 로고    scopus 로고
    • Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus
    • Gebhardt T, et al. 2009. Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus. Nat. Immunol. 10:524-530.
    • (2009) Nat. Immunol , vol.10 , pp. 524-530
    • Gebhardt, T.1
  • 17
    • 80052555420 scopus 로고    scopus 로고
    • Different patterns of peripheral migration by memory CD4+ and CD8+ T cells
    • Gebhardt T, et al. 2011. Different patterns of peripheral migration by memory CD4+ and CD8+ T cells. Nature 477:216-219.
    • (2011) Nature , vol.477 , pp. 216-219
    • Gebhardt, T.1
  • 18
    • 11844263985 scopus 로고    scopus 로고
    • Programmed expression of cutaneous lymphocyte-associated antigen amongst circulating memory T-cells specific for HSV-2
    • Gonzalez JC, Kwok WW, Wald A, McClurkan CL, Koelle DM. 2005. Programmed expression of cutaneous lymphocyte-associated antigen amongst circulating memory T-cells specific for HSV-2. J. Infect. Dis. 191:243-254.
    • (2005) J. Infect. Dis , vol.191 , pp. 243-254
    • Gonzalez, J.C.1    Kwok, W.W.2    Wald, A.3    McClurkan, C.L.4    Koelle, D.M.5
  • 19
    • 0021891101 scopus 로고
    • Immune-specific interferon production by peripheral blood mononuclear leukocytes from patients with primary and recurrent oro-labial herpes simplex virus infections
    • Green JA, Weiss PN, Yeh TJ, Spruance SL. 1985. Immune-specific interferon production by peripheral blood mononuclear leukocytes from patients with primary and recurrent oro-labial herpes simplex virus infections. J. Med. Virol. 16:297-305.
    • (1985) J. Med. Virol , vol.16 , pp. 297-305
    • Green, J.A.1    Weiss, P.N.2    Yeh, T.J.3    Spruance, S.L.4
  • 20
    • 11844306664 scopus 로고    scopus 로고
    • Functional heterogeneity of memory CD4 T cell responses in different conditions of antigen exposure and persistence
    • Harari A, Vallelian F, Meylan PR, Pantaleo G. 2005. Functional heterogeneity of memory CD4 T cell responses in different conditions of antigen exposure and persistence. J. Immunol. 174:1037-1045.
    • (2005) J. Immunol , vol.174 , pp. 1037-1045
    • Harari, A.1    Vallelian, F.2    Meylan, P.R.3    Pantaleo, G.4
  • 21
    • 10944231313 scopus 로고    scopus 로고
    • Phenotypic heterogeneity of antigen-specific CD4 T cells under different conditions of antigen persistence and antigen load
    • Harari A, Vallelian F, Pantaleo G. 2004. Phenotypic heterogeneity of antigen-specific CD4 T cells under different conditions of antigen persistence and antigen load. Eur. J. Immunol. 34:3525-3533.
    • (2004) Eur. J. Immunol , vol.34 , pp. 3525-3533
    • Harari, A.1    Vallelian, F.2    Pantaleo, G.3
  • 22
    • 77952624460 scopus 로고    scopus 로고
    • Comparison of interlaboratory variation in absolute T-cell counts by single-platform and optimized dual-platform methods
    • Hultin LE, et al. 2010. Comparison of interlaboratory variation in absolute T-cell counts by single-platform and optimized dual-platform methods. Cytometry B Clin. Cytom. 78:194-200.
    • (2010) Cytometry B Clin. Cytom , vol.78 , pp. 194-200
    • Hultin, L.E.1
  • 23
    • 33644853807 scopus 로고    scopus 로고
    • A whole blood assay to assess peripheral blood dendritic cell function in response to Toll-like receptor stimulation
    • Ida JA, et al. 2006. A whole blood assay to assess peripheral blood dendritic cell function in response to Toll-like receptor stimulation. J. Immunol. Methods 310:86-99.
    • (2006) J. Immunol. Methods , vol.310 , pp. 86-99
    • Ida, J.A.1
  • 24
    • 0036305574 scopus 로고    scopus 로고
    • Quantitative stability of DNA after extended storage of clinical specimens as determined by real-time PCR
    • Jerome KR, Huang ML, Wald A, Selke S, Corey L. 2002. Quantitative stability of DNA after extended storage of clinical specimens as determined by real-time PCR. J. Clin. Microbiol. 40:2609-2611.
    • (2002) J. Clin. Microbiol , vol.40 , pp. 2609-2611
    • Jerome, K.R.1    Huang, M.L.2    Wald, A.3    Selke, S.4    Corey, L.5
  • 25
    • 84863011888 scopus 로고    scopus 로고
    • Herpes simplex virus type 1 T-cells antigens in humans revealed by cross-presentation and genome-wide screening
    • Jing L, et al. 2012. Herpes simplex virus type 1 T-cells antigens in humans revealed by cross-presentation and genome-wide screening. J. Clin. Invest. 122:654-673.
    • (2012) J. Clin. Invest , vol.122 , pp. 654-673
    • Jing, L.1
  • 26
    • 10344257508 scopus 로고    scopus 로고
    • Herpesvirus-specific CD8 T cell immunity in old age: cytomegalovirus impairs the response to a coresident EBV infection
    • Khan N, et al. 2004. Herpesvirus-specific CD8 T cell immunity in old age: cytomegalovirus impairs the response to a coresident EBV infection. J. Immunol. 173:7481-7489.
    • (2004) J. Immunol , vol.173 , pp. 7481-7489
    • Khan, N.1
  • 27
    • 35748950423 scopus 로고    scopus 로고
    • Impaired plasmacytoid dendritic cell innate immune responses in patients with herpes virus-associated acute retinal necrosis
    • Kittan NA, et al. 2007. Impaired plasmacytoid dendritic cell innate immune responses in patients with herpes virus-associated acute retinal necrosis. J. Immunol. 179:4219-4230.
    • (2007) J. Immunol , vol.179 , pp. 4219-4230
    • Kittan, N.A.1
  • 28
    • 35948988938 scopus 로고    scopus 로고
    • Cytomegalovirus infection: a driving force in human T cell immunosenescence
    • Koch S, et al. 2007. Cytomegalovirus infection: a driving force in human T cell immunosenescence. Ann. N. Y. Acad. Sci. 1114:23-35.
    • (2007) Ann. N. Y. Acad. Sci , vol.1114 , pp. 23-35
    • Koch, S.1
  • 29
    • 0027991985 scopus 로고
    • Direct recovery of HSV-specific T lymphocyte clones from human recurrent HSV-2 lesions
    • Koelle DM, Abbo H, Peck A, Ziegweid K, Corey L. 1994. Direct recovery of HSV-specific T lymphocyte clones from human recurrent HSV-2 lesions. J. Infect. Dis. 169:956-961.
    • (1994) J. Infect. Dis , vol.169 , pp. 956-961
    • Koelle, D.M.1    Abbo, H.2    Peck, A.3    Ziegweid, K.4    Corey, L.5
  • 30
    • 0028301850 scopus 로고
    • Antigenic specificity of human CD4+ T cell clones recovered from recurrent genital HSV-2 lesions
    • Koelle DM, et al. 1994. Antigenic specificity of human CD4+ T cell clones recovered from recurrent genital HSV-2 lesions. J. Virol. 68:2803-2810.
    • (1994) J. Virol , vol.68 , pp. 2803-2810
    • Koelle, D.M.1
  • 31
    • 0001585502 scopus 로고    scopus 로고
    • Clearance of HSV-2 from recurrent genital lesions correlates with infiltration of HSV-specific cytotoxic T lymphocytes
    • Koelle DM, et al. 1998. Clearance of HSV-2 from recurrent genital lesions correlates with infiltration of HSV-specific cytotoxic T lymphocytes. J. Clin. Invest. 101:1500-1508.
    • (1998) J. Clin. Invest , vol.101 , pp. 1500-1508
    • Koelle, D.M.1
  • 32
    • 0034469402 scopus 로고    scopus 로고
    • Tegument-specific, virus-reactive CD4 T cells localize to the cornea in herpes simplex virus interstitial keratitis in humans
    • Koelle DM, et al. 2000. Tegument-specific, virus-reactive CD4 T cells localize to the cornea in herpes simplex virus interstitial keratitis in humans. J. Virol. 74:10930-10938.
    • (2000) J. Virol , vol.74 , pp. 10930-10938
    • Koelle, D.M.1
  • 33
    • 0034467661 scopus 로고    scopus 로고
    • CD4 T-cell responses to herpes simplex virus type 2 major capsid protein VP5: comparison with responses to tegument and envelope glycoproteins
    • Koelle DM, Schomogyi M, McClurkan C, Reymond SN, Chen HB. 2000. CD4 T-cell responses to herpes simplex virus type 2 major capsid protein VP5: comparison with responses to tegument and envelope glycoproteins. J. Virol. 74:11422-11425.
    • (2000) J. Virol , vol.74 , pp. 11422-11425
    • Koelle, D.M.1    Schomogyi, M.2    McClurkan, C.3    Reymond, S.N.4    Chen, H.B.5
  • 34
    • 77957594058 scopus 로고    scopus 로고
    • Diversity in CD8(+) T cell function and epitope breadth among persons with genital herpes
    • Laing KJ, et al. 2010. Diversity in CD8(+) T cell function and epitope breadth among persons with genital herpes. J. Clin. Immunol. 30:703-722.
    • (2010) J. Clin. Immunol , vol.30 , pp. 703-722
    • Laing, K.J.1
  • 35
    • 0042123694 scopus 로고    scopus 로고
    • Toll-like receptor 9-mediated recognition of herpes simplex virus-2 by plasmacytoid dendritic cells
    • Lund J, Sato A, Akira S, Medzhitov R, Iwasaki A. 2003. Toll-like receptor 9-mediated recognition of herpes simplex virus-2 by plasmacytoid dendritic cells. J. Exp. Med. 198:513-520.
    • (2003) J. Exp. Med , vol.198 , pp. 513-520
    • Lund, J.1    Sato, A.2    Akira, S.3    Medzhitov, R.4    Iwasaki, A.5
  • 36
    • 33947373530 scopus 로고    scopus 로고
    • Optimizing PCR positivity criterion for detection of herpes simplex virusDNAon skin and mucosa
    • Magaret AS, Wald A, Huang ML, Selke S, Corey L. 2007. Optimizing PCR positivity criterion for detection of herpes simplex virusDNAon skin and mucosa. J. Clin. Microbiol. 45:1618-1620.
    • (2007) J. Clin. Microbiol , vol.45 , pp. 1618-1620
    • Magaret, A.S.1    Wald, A.2    Huang, M.L.3    Selke, S.4    Corey, L.5
  • 37
    • 34247467903 scopus 로고    scopus 로고
    • Topical Resiquimod 0.01% gel decreases herpes simplex virus type 2 genital shedding: a randomized, controlled trial
    • Mark KE, et al. 2007. Topical Resiquimod 0.01% gel decreases herpes simplex virus type 2 genital shedding: a randomized, controlled trial. J. Infect. Dis. 195:1324-1331.
    • (2007) J. Infect. Dis , vol.195 , pp. 1324-1331
    • Mark, K.E.1
  • 38
    • 0035086920 scopus 로고    scopus 로고
    • Herpes simplex virus-specific immune responses in subjects with frequent and infrequent orofacial recrudescences
    • McKenna DB, Neill WA, Norval M. 2001. Herpes simplex virus-specific immune responses in subjects with frequent and infrequent orofacial recrudescences. Br. J. Dermatol. 144:459-464.
    • (2001) Br. J. Dermatol , vol.144 , pp. 459-464
    • McKenna, D.B.1    Neill, W.A.2    Norval, M.3
  • 39
    • 84862068459 scopus 로고    scopus 로고
    • Genetic variation in Toll-like receptors and disease susceptibility
    • Netea MG, Wijmenga C, O'Neill LA. 2012. Genetic variation in Toll-like receptors and disease susceptibility. Nat. Immunol. 13:535-542.
    • (2012) Nat. Immunol , vol.13 , pp. 535-542
    • Netea, M.G.1    Wijmenga, C.2    O'Neill, L.A.3
  • 40
    • 0004149270 scopus 로고
    • Applied linear statistical models
    • 3rd ed. Irwin Press, Homewood, IL
    • Neter J, Wasserman W, Kutner MH. 1990. Applied linear statistical models, 3rd ed. Irwin Press, Homewood, IL.
    • (1990)
    • Neter, J.1    Wasserman, W.2    Kutner, M.H.3
  • 41
    • 77957018085 scopus 로고    scopus 로고
    • Human TRAF3 adaptor molecule deficiency leads to impaired Toll-like receptor 3 response and susceptibility to herpes simplex encephalitis
    • Perez de Diego R, et al. 2010. Human TRAF3 adaptor molecule deficiency leads to impaired Toll-like receptor 3 response and susceptibility to herpes simplex encephalitis. Immunity 33:400-411.
    • (2010) Immunity , vol.33 , pp. 400-411
    • Perez de Diego, R.1
  • 42
    • 0030961152 scopus 로고    scopus 로고
    • Severe genital herpes infections in HIV-infected individuals with impaired HSVspecific CD8+ cytotoxic T lymphocyte responses
    • Posavad CM, Koelle DM, Shaughnessy MF, Corey L. 1997. Severe genital herpes infections in HIV-infected individuals with impaired HSVspecific CD8+ cytotoxic T lymphocyte responses. Proc. Natl. Acad. Sci. U. S. A. 94:10289-10294.
    • (1997) Proc. Natl. Acad. Sci. U. S. A , vol.94 , pp. 10289-10294
    • Posavad, C.M.1    Koelle, D.M.2    Shaughnessy, M.F.3    Corey, L.4
  • 43
    • 34447260501 scopus 로고    scopus 로고
    • The cytomegalovirus-specific CD4+ T-cell response expands with age and markedly alters the CD4+ T-cell repertoire
    • Pourgheysari B, et al. 2007. The cytomegalovirus-specific CD4+ T-cell response expands with age and markedly alters the CD4+ T-cell repertoire. J. Virol. 81:7759-7765.
    • (2007) J. Virol , vol.81 , pp. 7759-7765
    • Pourgheysari, B.1
  • 44
    • 0015988086 scopus 로고
    • Lymphocyte interferon production and transformation after herpes simplex infections in humans
    • Rasmussen LE, Jordan GW, Stevens DA, Merigan TC. 1974. Lymphocyte interferon production and transformation after herpes simplex infections in humans. J. Immunol. 112:728-736.
    • (1974) J. Immunol , vol.112 , pp. 728-736
    • Rasmussen, L.E.1    Jordan, G.W.2    Stevens, D.A.3    Merigan, T.C.4
  • 45
    • 84055190795 scopus 로고    scopus 로고
    • Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency
    • Sancho-Shimizu V, et al. 2011. Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency. J. Clin. Invest. 121:4889-4902.
    • (2011) J. Clin. Invest , vol.121 , pp. 4889-4902
    • Sancho-Shimizu, V.1
  • 46
    • 33751206873 scopus 로고    scopus 로고
    • Dual recognition of herpes simplex viruses by TLR2 and TLR9 in dendritic cells
    • Sato A, Linehan MM, Iwasaki A. 2006. Dual recognition of herpes simplex viruses by TLR2 and TLR9 in dendritic cells. Proc. Natl. Acad. Sci. U. S. A. 103:17343-17348.
    • (2006) Proc. Natl. Acad. Sci. U. S. A , vol.103 , pp. 17343-17348
    • Sato, A.1    Linehan, M.M.2    Iwasaki, A.3
  • 47
    • 0030794379 scopus 로고    scopus 로고
    • Characterization of T cell responses to herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2) using a TNF-beta ELISpot cytokine assay
    • Schmid DS, Thieme ML, Gary HE, Reeves WC. 1997. Characterization of T cell responses to herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2) using a TNF-beta ELISpot cytokine assay. Arch. Virol. 142:1659-1671.
    • (1997) Arch. Virol , vol.142 , pp. 1659-1671
    • Schmid, D.S.1    Thieme, M.L.2    Gary, H.E.3    Reeves, W.C.4
  • 48
    • 73949129044 scopus 로고    scopus 로고
    • Co-ordinated regulation of plasmacytoid dendritic cell surface receptors upon stimulation with herpes simplex virus type 1
    • Schuster P, et al. 2010. Co-ordinated regulation of plasmacytoid dendritic cell surface receptors upon stimulation with herpes simplex virus type 1. Immunology 129:234-247.
    • (2010) Immunology , vol.129 , pp. 234-247
    • Schuster, P.1
  • 49
    • 0033546053 scopus 로고    scopus 로고
    • The nature of the principle type 1 interferonproducing cells in human blood
    • Siegal FP, et al. 1999. The nature of the principle type 1 interferonproducing cells in human blood. Science 284:1835-1837.
    • (1999) Science , vol.284 , pp. 1835-1837
    • Siegal, F.P.1
  • 50
    • 0348140688 scopus 로고    scopus 로고
    • Epidemiology of recurrent genital herpes simplex virus types 1 and 2
    • Solomon L, et al. 2003. Epidemiology of recurrent genital herpes simplex virus types 1 and 2. Sex. Transm. Infect. 79:456-459.
    • (2003) Sex. Transm. Infect , vol.79 , pp. 456-459
    • Solomon, L.1
  • 51
    • 58849152815 scopus 로고    scopus 로고
    • TLR2 and TLR9 synergistically control herpes simplex virus infection in the brain.
    • Sorensen LN, et al. 2008. TLR2 and TLR9 synergistically control herpes simplex virus infection in the brain. J. Immunol. 181:8604-8612.
    • (2008) J. Immunol , vol.181 , pp. 8604-8612
    • Sorensen, L.N.1
  • 52
    • 0029115451 scopus 로고
    • Th1/Th2-like immunity and resistance to herpes simplex labialis
    • Spruance SL, et al. 1995. Th1/Th2-like immunity and resistance to herpes simplex labialis. Antiviral Res. 28:39-55.
    • (1995) Antiviral Res , vol.28 , pp. 39-55
    • Spruance, S.L.1
  • 53
    • 0029146351 scopus 로고
    • Susceptibility to herpes labialis following multiple experimental exposures to ultraviolet radiation
    • Spruance SL, Kriesel JD, Evans TG, McKeough MB. 1995. Susceptibility to herpes labialis following multiple experimental exposures to ultraviolet radiation. Antiviral Res. 28:57-67.
    • (1995) Antiviral Res , vol.28 , pp. 57-67
    • Spruance, S.L.1    Kriesel, J.D.2    Evans, T.G.3    McKeough, M.B.4
  • 54
    • 24344489044 scopus 로고    scopus 로고
    • Broadly targeted human cytomegalovirusspecific CD4+and CD8+T cells dominate the memory compartments of exposed subjects
    • Sylwester AW, et al. 2005. Broadly targeted human cytomegalovirusspecific CD4+and CD8+T cells dominate the memory compartments of exposed subjects. J. Exp. Med. 202:673-685.
    • (2005) J. Exp. Med , vol.202 , pp. 673-685
    • Sylwester, A.W.1
  • 55
    • 78649711598 scopus 로고    scopus 로고
    • Defect of plasmacytoid dendritic cells in warts, hypogammaglobulinemia, infections, myelokathexis (WHIM) syndrome patients
    • Tassone L, et al. 2010. Defect of plasmacytoid dendritic cells in warts, hypogammaglobulinemia, infections, myelokathexis (WHIM) syndrome patients. Blood 116:4870-4873.
    • (2010) Blood , vol.116 , pp. 4870-4873
    • Tassone, L.1
  • 56
    • 77956806437 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells: an overview of their presence and distribution in different inflammatory skin diseases, with special emphasis on Jessner's lymphocytic infiltrate of the skin and cutaneous lupus erythematosus
    • Tomasini D, et al. 2010. Plasmacytoid dendritic cells: an overview of their presence and distribution in different inflammatory skin diseases, with special emphasis on Jessner's lymphocytic infiltrate of the skin and cutaneous lupus erythematosus. J. Cutan. Pathol. 37:1132-1139.
    • (2010) J. Cutan. Pathol , vol.37 , pp. 1132-1139
    • Tomasini, D.1
  • 57
    • 79953848750 scopus 로고    scopus 로고
    • Genital shedding of herpes simplex virus among symptomatic and asymptomatic persons with HSV-2 infection
    • Tronstein E, et al. 2011. Genital shedding of herpes simplex virus among symptomatic and asymptomatic persons with HSV-2 infection. JAMA 305:1441-1449.
    • (2011) JAMA , vol.305 , pp. 1441-1449
    • Tronstein, E.1
  • 58
    • 35748936769 scopus 로고    scopus 로고
    • Massive load of functional effector CD4+ and CD8+ T cells against cytomegalovirus in very old subjects
    • Vescovini R, et al. 2007. Massive load of functional effector CD4+ and CD8+ T cells against cytomegalovirus in very old subjects. J. Immunol. 179:4283-4291.
    • (2007) J. Immunol , vol.179 , pp. 4283-4291
    • Vescovini, R.1
  • 59
    • 0024346975 scopus 로고
    • Variation in lymphoproliferative responses during recrudescent orofacial herpes simplex virus infections
    • Vestey JP, Norval M, Howie S, Maingay J, Neill WA. 1989. Variation in lymphoproliferative responses during recrudescent orofacial herpes simplex virus infections. Clin. Exp. Immunol. 77:384-390.
    • (1989) Clin. Exp. Immunol , vol.77 , pp. 384-390
    • Vestey, J.P.1    Norval, M.2    Howie, S.3    Maingay, J.4    Neill, W.A.5
  • 60
    • 38149001476 scopus 로고    scopus 로고
    • Dendritic cell-induced memory T cell activation in nonlymphoid tissues
    • Wakim LM, Waithman J, van Rooijen N, Heath WR, Carbone FR. 2008. Dendritic cell-induced memory T cell activation in nonlymphoid tissues. Science 319:198-202.
    • (2008) Science , vol.319 , pp. 198-202
    • Wakim, L.M.1    Waithman, J.2    van Rooijen, N.3    Heath, W.R.4    Carbone, F.5
  • 61
    • 0242721032 scopus 로고    scopus 로고
    • Polymerase chain reaction for detection of herpes simplex virus (HSV) DNA on mucosal surfaces: comparison with HSV isolation in cell culture
    • Wald A, Huang ML, Carrell D, Selke S, Corey L. 2003. Polymerase chain reaction for detection of herpes simplex virus (HSV) DNA on mucosal surfaces: comparison with HSV isolation in cell culture. J. Infect. Dis. 188:1345-1351.
    • (2003) J. Infect. Dis , vol.188 , pp. 1345-1351
    • Wald, A.1    Huang, M.L.2    Carrell, D.3    Selke, S.4    Corey, L.5
  • 62
    • 82455192355 scopus 로고    scopus 로고
    • Safety and immunogenicity of long HSV-2 peptides complexed with rhHsc70 in HSV-2 seropositive persons
    • Wald A, et al. 2011. Safety and immunogenicity of long HSV-2 peptides complexed with rhHsc70 in HSV-2 seropositive persons. Vaccine 29: 8520-8529.
    • (2011) Vaccine , vol.29 , pp. 8520-8529
    • Wald, A.1
  • 63
    • 0034704798 scopus 로고    scopus 로고
    • Reactivation of genital herpes simplex virus type 2 infection in asymptomatic seropositive persons
    • Wald A, et al. 2000. Reactivation of genital herpes simplex virus type 2 infection in asymptomatic seropositive persons. N. Engl. J. Med. 342:844-850.
    • (2000) N. Engl. J. Med , vol.342 , pp. 844-850
    • Wald, A.1
  • 64
    • 84864058577 scopus 로고    scopus 로고
    • Association of TLR3-hyporesponsiveness and functional TLR3 L412F polymorphism with recurrent herpes labialis
    • Yang CA, et al. 2012. Association of TLR3-hyporesponsiveness and functional TLR3 L412F polymorphism with recurrent herpes labialis. Hum. Immunol. 73:844-851
    • (2012) Hum. Immunol. , vol.73 , pp. 844-851
    • Yang, C.A.1
  • 65
    • 0021260798 scopus 로고
    • Human cytotoxic T cell clones directed against herpes simplex virus-infected cells. I. Lysis restricted by HLA class II MB and DR antigens
    • Yasukawa M, Zarling JM. 1984. Human cytotoxic T cell clones directed against herpes simplex virus-infected cells. I. Lysis restricted by HLA class II MB and DR antigens. J. Immunol. 133:422-427.
    • (1984) J. Immunol , vol.133 , pp. 422-427
    • Yasukawa, M.1    Zarling, J.M.2
  • 66
    • 23744464502 scopus 로고    scopus 로고
    • Plasmacytoid DCs help lymph node DCs to induce anti-HSV CTLs
    • Yoneyama H, et al. 2005. Plasmacytoid DCs help lymph node DCs to induce anti-HSV CTLs. J. Exp. Med. 202:425-435.
    • (2005) J. Exp. Med , vol.202 , pp. 425-435
    • Yoneyama, H.1
  • 67
    • 34548699323 scopus 로고    scopus 로고
    • TLR3 deficiency in patients with herpes simplex encephalitis
    • Zhang SY, et al. 2007. TLR3 deficiency in patients with herpes simplex encephalitis. Science 317:1522-1527.
    • (2007) Science , vol.317 , pp. 1522-1527
    • Zhang, S.Y.1
  • 68
    • 68349146396 scopus 로고    scopus 로고
    • Persistence of HIV-1 receptor-positive cells after HSV-2 reactivation is a potential mechanism for increased HIV-1 acquisition. Nat. Med. 15:886-892.
    • Zhu J, et al. 2009. Persistence of HIV-1 receptor-positive cells after HSV-2 reactivation is a potential mechanism for increased HIV-1 acquisition. Nat. Med. 15:886-892.
    • (2009) Nat. Med , vol.15 , pp. 886-892
    • Zhu, J.1
  • 69
    • 33947424353 scopus 로고    scopus 로고
    • Virus-specific CD8+ T cells accumulate near sensory nerve endings in genital skin during subclinical HSV-2 reactivation
    • Zhu J, et al. 2007. Virus-specific CD8+ T cells accumulate near sensory nerve endings in genital skin during subclinical HSV-2 reactivation. J. Exp. Med. 204:595-603.
    • (2007) J. Exp. Med , vol.204 , pp. 595-603
    • Zhu, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.