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Volumn 18, Issue 3, 2012, Pages 208-214

Effect of exercise on the immune system: Response, adaptation and cell signaling

Author keywords

Cell signaling; Cytokines; Effector cells; Physical activity

Indexed keywords


EID: 84866126339     PISSN: 15178692     EISSN: None     Source Type: Journal    
DOI: 10.1590/S1517-86922012000300015     Document Type: Review
Times cited : (61)

References (107)
  • 1
    • 47949104798 scopus 로고    scopus 로고
    • The role of exercise and PGC1α in inflammation and chronic disease
    • Handschin C, Spiegelman BM. The role of exercise and PGC1α in inflammation and chronic disease. Nature 2008;454:463-9.
    • (2008) Nature , vol.454 , pp. 463-469
    • Handschin, C.1    Spiegelman, B.M.2
  • 2
    • 0033922490 scopus 로고    scopus 로고
    • Exercise and the immune system: Regulation integration and adaption
    • Pedersen BK, Hoffman-Goetz L. Exercise and the immune system: Regulation integration and adaption. Physiol Reviews 2000;80:1055-81.
    • (2000) Physiol Reviews , vol.80 , pp. 1055-1081
    • Pedersen, B.K.1    Hoffman-Goetz, L.2
  • 3
    • 27144463109 scopus 로고    scopus 로고
    • Influências do exercício na reposta imune
    • Rosa LF, Vaisberg MW. Influências do exercício na reposta imune. Rev Bras Med Esporte 2002;8:167-72.
    • (2002) Rev Bras Med Esporte , vol.8 , pp. 167-172
    • Rosa, L.F.1    Vaisberg, M.W.2
  • 5
    • 0032088943 scopus 로고    scopus 로고
    • ACSM Position Stand: The Recommended Quantity And Quality Of Exercise For Developing And Maintaining Cardiorespiratory And Muscular Fitness, And Flexibility In Healthy Adults
    • Pollock ML, Gaesser GA, Butcher JD, Després J-P, Dishman RK, Franklin BA, et al. ACSM Position Stand: The Recommended Quantity And Quality Of Exercise For Developing And Maintaining Cardiorespiratory And Muscular Fitness, And Flexibility In Healthy Adults. Med Sci Sports Exerc 1998;30:975-91.
    • (1998) Med Sci Sports Exerc , vol.30 , pp. 975-991
    • Pollock, M.L.1    Gaesser, G.A.2    Butcher, J.D.3    Després, J.-P.4    Dishman, R.K.5    Franklin, B.A.6
  • 6
    • 34548239152 scopus 로고    scopus 로고
    • Physical Activity and Public Health: Updated Recommendation for Adults from the American College of Sports Medicine and the American Heart Association
    • Haskell WL, Lee I-M, Pate RR, Powell KE, Blair SN, Franklin BA, et al. Physical Activity and Public Health: Updated Recommendation for Adults from the American College of Sports Medicine and the American Heart Association. Med Sci Sports Exerc 2007;39:1423-34.
    • (2007) Med Sci Sports Exerc , vol.39 , pp. 1423-1434
    • Haskell, W.L.1    Lee, I.-M.2    Pate, R.R.3    Powell, K.E.4    Blair, S.N.5    Franklin, B.A.6
  • 8
    • 0026276529 scopus 로고
    • Type 1 T helper and type 2 T helper cells: Functions, regulation and role in protection and disease
    • Romagnani S. Type 1 T helper and type 2 T helper cells: functions, regulation and role in protection and disease. Int J Clin Lab Res 1991;21:152-8.
    • (1991) Int J Clin Lab Res , vol.21 , pp. 152-158
    • Romagnani, S.1
  • 9
    • 56149117105 scopus 로고    scopus 로고
    • The complexity of the CD4 T-cell responses: Old and new T-cell subsets
    • Del Prete G. The complexity of the CD4 T-cell responses: old and new T-cell subsets. Parassitologia 2008;50:9-16.
    • (2008) Parassitologia , vol.50 , pp. 9-16
    • Del Prete, G.1
  • 13
    • 1942453342 scopus 로고    scopus 로고
    • Historical review: Cytokines as therapeutic and targets of therapeutics
    • Vilcek J, Feldman M. Historical review: cytokines as therapeutic and targets of therapeutics. Trends Pharmacol Sci 2004;25:201.
    • (2004) Trends Pharmacol Sci , vol.25 , pp. 201
    • Vilcek, J.1    Feldman, M.2
  • 14
    • 0033669568 scopus 로고    scopus 로고
    • Neuroendocrine regulation of IL-12 and TNF-alpha/IL-10 balance. Clinical implications
    • Elenkov IJ, Chrousos GP, Wilder RL. Neuroendocrine regulation of IL-12 and TNF-alpha/IL-10 balance. Clinical implications. Ann NY Acad Sci 2000;917:94-105.
    • (2000) Ann NY Acad Sci , vol.917 , pp. 94-105
    • Elenkov, I.J.1    Chrousos, G.P.2    Wilder, R.L.3
  • 15
    • 0034556980 scopus 로고    scopus 로고
    • Infammatory cytokines in nonpathological states
    • Cannon JG. Infammatory cytokines in nonpathological states. News Physiol Sci 2000;15:298-303.
    • (2000) News Physiol Sci , vol.15 , pp. 298-303
    • Cannon, J.G.1
  • 16
    • 0031132212 scopus 로고    scopus 로고
    • In vivo production and function of IL-12p40 homodimers
    • Heinzel F, Hujer A, Ahmed F, Rerko R. In vivo production and function of IL-12p40 homodimers. J Immunol 1997;158:4381-8.
    • (1997) J Immunol , vol.158 , pp. 4381-4388
    • Heinzel, F.1    Hujer, A.2    Ahmed, F.3    Rerko, R.4
  • 17
    • 0036839217 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 selectively inhibits the acquisition of CD40 ligand-dependent IL-12-producing capacity of monocyte-derived dendritic cells and modulates Th1 immune response
    • Omata N, Yasutomi M, Yamada A, Iwasaki H, Mayumi M, Ohshima Y. Monocyte chemoattractant protein-1 selectively inhibits the acquisition of CD40 ligand-dependent IL-12-producing capacity of monocyte-derived dendritic cells and modulates Th1 immune response. J Immunol 2002;169:4861-6.
    • (2002) J Immunol , vol.169 , pp. 4861-4866
    • Omata, N.1    Yasutomi, M.2    Yamada, A.3    Iwasaki, H.4    Mayumi, M.5    Ohshima, Y.6
  • 18
    • 0030227883 scopus 로고    scopus 로고
    • Modulatory effects of glucocorticoids and catecholamines on human interleukin-12 and interleukin-10 production: Clinical implications
    • Elenkov IJ, Papanicolaou DA, Wilder RL, Chrousos GP. Modulatory effects of glucocorticoids and catecholamines on human interleukin-12 and interleukin-10 production: clinical implications. Proc Assoc Am Physicians 1996;108:374-81.
    • (1996) Proc Assoc Am Physicians , vol.108 , pp. 374-381
    • Elenkov, I.J.1    Papanicolaou, D.A.2    Wilder, R.L.3    Chrousos, G.P.4
  • 19
    • 0029925751 scopus 로고    scopus 로고
    • Glucocorticoids promote a Th2 cytokine response by CD4+ T cells in vitro
    • Ramirez F, Fowell DJ, Puklavec M, Simmonds S, Mason D. Glucocorticoids promote a Th2 cytokine response by CD4+ T cells in vitro. J Immunol 1996;156:2406-12.
    • (1996) J Immunol , vol.156 , pp. 2406-2412
    • Ramirez, F.1    Fowell, D.J.2    Puklavec, M.3    Simmonds, S.4    Mason, D.5
  • 20
    • 0031570475 scopus 로고    scopus 로고
    • Corticosteroids inhibit IL-12 production in human monocytes and enhance their capacity to induce IL-4 synthesis in CD4+ lymphocytes
    • Blotta MH, DeKruy RH, Umetsu DT. Corticosteroids inhibit IL-12 production in human monocytes and enhance their capacity to induce IL-4 synthesis in CD4+ lymphocytes. J Immunol 1997;158:5589-95.
    • (1997) J Immunol , vol.158 , pp. 5589-5595
    • Blotta, M.H.1    Dekruy, R.H.2    Umetsu, D.T.3
  • 21
    • 0033958712 scopus 로고    scopus 로고
    • Beta-adrenergic modulation of human type-1/type-2 cytokine balance
    • Agarwal SK, Marshall GD. Beta-adrenergic modulation of human type-1/type-2 cytokine balance. J Allergy Clin Immunol 2000;105:91-8.
    • (2000) J Allergy Clin Immunol , vol.105 , pp. 91-98
    • Agarwal, S.K.1    Marshall, G.D.2
  • 22
    • 0031283083 scopus 로고    scopus 로고
    • Prostaglandin E2 primes naive T cells for the production of anti-inflammatory cytokines
    • Demeure CE, Yang LP, Desjardins C, Raynauld P, Delespesse G. Prostaglandin E2 primes naive T cells for the production of anti-inflammatory cytokines. Eur J Immunol 1997;27:3526-31.
    • (1997) Eur J Immunol , vol.27 , pp. 3526-3531
    • Demeure, C.E.1    Yang, L.P.2    Desjardins, C.3    Raynauld, P.4    Delespesse, G.5
  • 23
    • 0035383783 scopus 로고    scopus 로고
    • Prostaglandin E2 is a selective inducer of interleukin-12 p40 (IL-12p40) production and an inhibitor of bioactive IL-12p70 heterodimer
    • Kalinski P, Vieira PL, Schuitemaker JH, De Jong EC, Kapsenberg ML. Prostaglandin E2 is a selective inducer of interleukin-12 p40 (IL-12p40) production and an inhibitor of bioactive IL-12p70 heterodimer. Blood 2001;97:3466-9.
    • (2001) Blood , vol.97 , pp. 3466-3469
    • Kalinski, P.1    Vieira, P.L.2    Schuitemaker, J.H.3    de Jong, E.C.4    Kapsenberg, M.L.5
  • 24
    • 0034529290 scopus 로고    scopus 로고
    • Changes in plasma concentrations of interleukin-6 and interleukin-1 receptor antagonists in response to adrenaline infusion in humans
    • Sondergaard SR, Ostrowski K, Ullum H, Pedersen BK. Changes in plasma concentrations of interleukin-6 and interleukin-1 receptor antagonists in response to adrenaline infusion in humans. Eur J Appl Physiol 2000;83:95-8.
    • (2000) Eur J Appl Physiol , vol.83 , pp. 95-98
    • Sondergaard, S.R.1    Ostrowski, K.2    Ullum, H.3    Pedersen, B.K.4
  • 26
    • 0033922490 scopus 로고    scopus 로고
    • Exercise and the immune system: Regulation integration and adaption
    • Pedersen BK, Hoffman-Goetz L. Exercise and the immune system: regulation integration and adaption. Physiol Rev 2000;80:1055-81.
    • (2000) Physiol Rev , vol.80 , pp. 1055-1081
    • Pedersen, B.K.1    Hoffman-Goetz, L.2
  • 27
    • 0033557703 scopus 로고    scopus 로고
    • Pro and anti-inflammatory cytokine balance in strenuous exercise in humans
    • Ostrowski K, Rohde T, Asp S, Schjerling P, Pedersen BK. Pro and anti-inflammatory cytokine balance in strenuous exercise in humans. J Physiol 1999;515:287-91.
    • (1999) J Physiol , vol.515 , pp. 287-291
    • Ostrowski, K.1    Rohde, T.2    Asp, S.3    Schjerling, P.4    Pedersen, B.K.5
  • 28
    • 55949119252 scopus 로고    scopus 로고
    • Muscle as an Endocrine Organ: Focus on Muscle-Derived Interleukin-6
    • Pedersen BK, Febbraio MA. Muscle as an Endocrine Organ: Focus on Muscle-Derived Interleukin-6. Physiol Rev 2008;88:1379-406.
    • (2008) Physiol Rev , vol.88 , pp. 1379-1406
    • Pedersen, B.K.1    Febbraio, M.A.2
  • 29
    • 0035886973 scopus 로고    scopus 로고
    • Muscle derived interleukin-6: Possible biological effects
    • Pedersen BK, Steensberg A, Schjerling P. Muscle derived interleukin-6: possible biological effects. J Physiol 2001;536:329-37.
    • (2001) J Physiol , vol.536 , pp. 329-337
    • Pedersen, B.K.1    Steensberg, A.2    Schjerling, P.3
  • 30
    • 0036720342 scopus 로고    scopus 로고
    • Muscle-derived interleukin-6: Mechanisms for activation and possible biological roles
    • Febbraio MA, Pedersen BK. Muscle-derived interleukin-6: mechanisms for activation and possible biological roles. FASEB J 2002;16:1335-47.
    • (2002) FASEB J , vol.16 , pp. 1335-1347
    • Febbraio, M.A.1    Pedersen, B.K.2
  • 32
    • 22244477735 scopus 로고    scopus 로고
    • Contraction-induced myokine production and release: Is skeletal muscle an endocrine organ?
    • Febbraio MA, Pedersen BK. Contraction-induced myokine production and release: is skeletal muscle an endocrine organ? Exerc Sport Sci Rev 2005;33:114-9.
    • (2005) Exerc Sport Sci Rev , vol.33 , pp. 114-119
    • Febbraio, M.A.1    Pedersen, B.K.2
  • 33
    • 34247130827 scopus 로고    scopus 로고
    • Physiological roles of muscle-derived interleukin-6 in response to exercise
    • Pedersen BK, Fischer CP. Physiological roles of muscle-derived interleukin-6 in response to exercise. Curr Opin Clin Nutr Metab Care 2007;10:265-71.
    • (2007) Curr Opin Clin Nutr Metab Care , vol.10 , pp. 265-271
    • Pedersen, B.K.1    Fischer, C.P.2
  • 34
    • 0034668926 scopus 로고    scopus 로고
    • Production of interleukin-6 in contracting human skeletal muscles can account for the exercise-induced increase in plasma interleukin-6
    • Steensberg A, van Hall G, Osada T, Sacchetti M, Saltin B, Klarlund PB. Production of interleukin-6 in contracting human skeletal muscles can account for the exercise-induced increase in plasma interleukin-6. J Physiol 2000;529:237-42.
    • (2000) J Physiol , vol.529 , pp. 237-242
    • Steensberg, A.1    van Hall, G.2    Osada, T.3    Sacchetti, M.4    Saltin, B.5    Klarlund, P.B.6
  • 35
    • 4344616150 scopus 로고    scopus 로고
    • Supplementation with vitamins C and E inhibits the release of interleukin-6 from contracting human skeletal muscle
    • Fischer CP, Hiscock N, Basu S, Vessby B, Kallner A, Sjoberg LB, et al. Supplementation with vitamins C and E inhibits the release of interleukin-6 from contracting human skeletal muscle. J Physiol 2004;558:633-45.
    • (2004) J Physiol , vol.558 , pp. 633-645
    • Fischer, C.P.1    Hiscock, N.2    Basu, S.3    Vessby, B.4    Kallner, A.5    Sjoberg, L.B.6
  • 36
    • 44649182268 scopus 로고    scopus 로고
    • Skeletal muscle as an immunogenic organ
    • Nielsen S, Pedersen BK. Skeletal muscle as an immunogenic organ. Curr Opin Pharmacol 2008;8:346-51.
    • (2008) Curr Opin Pharmacol , vol.8 , pp. 346-351
    • Nielsen, S.1    Pedersen, B.K.2
  • 37
    • 78651379305 scopus 로고    scopus 로고
    • Muscles and their myokines
    • Pedersen, B.K. Muscles and their myokines. J Exp Biol 2011;214:337-46.
    • (2011) J Exp Biol , vol.214 , pp. 337-346
    • Pedersen, B.K.1
  • 39
    • 34247610004 scopus 로고    scopus 로고
    • The Dual Roles of Neutrophils and Macrophages in Inflammation: A Critical Balance Between Tissue Damage and Repair
    • Butterfield TA, Best TM, Merrick MA. The Dual Roles of Neutrophils and Macrophages in Inflammation: A Critical Balance Between Tissue Damage and Repair. J Athle Training 2006;41:457-65.
    • (2006) J Athle Training , vol.41 , pp. 457-465
    • Butterfield, T.A.1    Best, T.M.2    Merrick, M.A.3
  • 40
    • 0035209356 scopus 로고    scopus 로고
    • Oxidant production and immune response after stretch injury in skeletal muscle
    • Brickson S, Hollander J, Corr DT, Ji LL, Best TM. Oxidant production and immune response after stretch injury in skeletal muscle. Med Sci Sports Exerc 2001;33:2010-5.
    • (2001) Med Sci Sports Exerc , vol.33 , pp. 2010-2015
    • Brickson, S.1    Hollander, J.2    Corr, D.T.3    Ji, L.L.4    Best, T.M.5
  • 41
    • 0034107870 scopus 로고    scopus 로고
    • Neutrophil function response to aerobic and anaerobic exercise in female judoka and untrained subjects
    • Wolach B, Falk B, Gavrieli R, Kodesh E, Eliakim A. Neutrophil function response to aerobic and anaerobic exercise in female judoka and untrained subjects. Br J Sports Med 2000;34:23-7.
    • (2000) Br J Sports Med , vol.34 , pp. 23-27
    • Wolach, B.1    Falk, B.2    Gavrieli, R.3    Kodesh, E.4    Eliakim, A.5
  • 43
    • 0034016469 scopus 로고    scopus 로고
    • Effect of oral glutamine supplementation on human neutrophil lipopolysaccharide-stimulated degranulation following prolonged exercise
    • Walsh, N. Effect of oral glutamine supplementation on human neutrophil lipopolysaccharide-stimulated degranulation following prolonged exercise. Int J Sport Nutr Exerc Metab 2000;10:39-50.
    • (2000) Int J Sport Nutr Exerc Metab , vol.10 , pp. 39-50
    • Walsh, N.1
  • 44
    • 33746584003 scopus 로고    scopus 로고
    • The effects of high-intensity exercise on skeletal muscle neutrophil myeloperoxidase in untrained and trained rats
    • Morozov VI, et al. The effects of high-intensity exercise on skeletal muscle neutrophil myeloperoxidase in untrained and trained rats. Eur J Appl Physiol 2006;97:716-22.
    • (2006) Eur J Appl Physiol , vol.97 , pp. 716-722
    • Morozov, V.I.1
  • 47
    • 0025237446 scopus 로고
    • Sympathoadrenergic regulation and the adrenoceptor system
    • Jost J, Weiss M, Weicker R. Sympathoadrenergic regulation and the adrenoceptor system. J Appl Physiol 1990;68:897-904.
    • (1990) J Appl Physiol , vol.68 , pp. 897-904
    • Jost, J.1    Weiss, M.2    Weicker, R.3
  • 48
    • 0033666278 scopus 로고    scopus 로고
    • Norepinephrine: A messenger from the brain to the immune system
    • Kohm AP, Sanders VM. Norepinephrine: a messenger from the brain to the immune system. Immunol Today 2000;21:539-42.
    • (2000) Immunol Today , vol.21 , pp. 539-542
    • Kohm, A.P.1    Sanders, V.M.2
  • 53
    • 0022589079 scopus 로고
    • The relationship of CD16 (Leu-11) and Leu-19 (NKH-1) antigen expression on human peripheral blood NK cells and cytotoxic T lymphocytes
    • Lanier LL, Le AM, Civin CI, Loken MR, Phillips JH. The relationship of CD16 (Leu-11) and Leu-19 (NKH-1) antigen expression on human peripheral blood NK cells and cytotoxic T lymphocytes. J Immunol 1986;136:4480-6.
    • (1986) J Immunol , vol.136 , pp. 4480-4486
    • Lanier, L.L.1    Le, A.M.2    Civin, C.I.3    Loken, M.R.4    Phillips, J.H.5
  • 54
    • 50949124847 scopus 로고    scopus 로고
    • Human natural killer cells
    • Caligiuri MA. Human natural killer cells. Blood 2008;112:461-9.
    • (2008) Blood , vol.112 , pp. 461-469
    • Caligiuri, M.A.1
  • 55
    • 0037606040 scopus 로고    scopus 로고
    • CD56bright natural killer cells are present in human lymph nodes and are activated by T cell-derived IL-2: A potential new link between adaptive and innate immunity
    • Fehniger TA, Cooper MA, Nuovo GJ, Cella M, Facchetti F, Colonna M, et al. CD56bright natural killer cells are present in human lymph nodes and are activated by T cell-derived IL-2: a potential new link between adaptive and innate immunity. Blood 2003;101:3052-7.
    • (2003) Blood , vol.101 , pp. 3052-3057
    • Fehniger, T.A.1    Cooper, M.A.2    Nuovo, G.J.3    Cella, M.4    Facchetti, F.5    Colonna, M.6
  • 56
    • 10744220243 scopus 로고    scopus 로고
    • Natural killer cells activated by MHC class I (low) targets prime dendritic cells to induce protective CD8 T cell responses
    • Mocikat R, Braumuller H, Gumy A, Egeter O, Ziegler H, Reusch U, et al. Natural killer cells activated by MHC class I (low) targets prime dendritic cells to induce protective CD8 T cell responses. Immun 2003;19:561-9.
    • (2003) Immun , vol.19 , pp. 561-569
    • Mocikat, R.1    Braumuller, H.2    Gumy, A.3    Egeter, O.4    Ziegler, H.5    Reusch, U.6
  • 57
    • 0024391085 scopus 로고
    • Comparative studies of human FcRIII-positive and negative natural killer cells
    • Nagler A, Lanier LL, Cwirla S, Phillips JH. Comparative studies of human FcRIII-positive and negative natural killer cells. J Immunol 1989;143:3183-91.
    • (1989) J Immunol , vol.143 , pp. 3183-3191
    • Nagler, A.1    Lanier, L.L.2    Cwirla, S.3    Phillips, J.H.4
  • 59
    • 62849118369 scopus 로고    scopus 로고
    • Human Natural Killer Cell Subsets and Acute Exercise: A Brief Review
    • Timmons BW, Cieslak T. Human Natural Killer Cell Subsets and Acute Exercise: A Brief Review. Exerc Immunol Rev 2008;14:8-23.
    • (2008) Exerc Immunol Rev , vol.14 , pp. 8-23
    • Timmons, B.W.1    Cieslak, T.2
  • 60
    • 0033696454 scopus 로고    scopus 로고
    • Mobilization of NK cells by exercise: Downmodulation of adhesion molecules on NK cells by catecholamines
    • Nagao F, Suzui M, Takeda K, Yagita H, Okumura K. Mobilization of NK cells by exercise: downmodulation of adhesion molecules on NK cells by catecholamines. Am J Physiol Regul Integr Comp Physiol 2000;279:R1251-6.
    • (2000) Am J Physiol Regul Integr Comp Physiol , vol.279
    • Nagao, F.1    Suzui, M.2    Takeda, K.3    Yagita, H.4    Okumura, K.5
  • 61
    • 0027074116 scopus 로고
    • Heart rate and plasma catecholamines during 24 h of everyday life in trained and untrained men
    • Dela F, Mikines KJ, Von Linstow M, Galbo H. Heart rate and plasma catecholamines during 24 h of everyday life in trained and untrained men. J Appl Physiol 1992;73:2389-95.
    • (1992) J Appl Physiol , vol.73 , pp. 2389-2395
    • Dela, F.1    Mikines, K.J.2    von Linstow, M.3    Galbo, H.4
  • 62
    • 0031115340 scopus 로고    scopus 로고
    • Circulationg levels of peripheral blood leukocytes and cytokines following competitive cycling
    • Gannon GA, Rhind SG, Suzui M, Shek PN, Shephard RJ. Circulationg levels of peripheral blood leukocytes and cytokines following competitive cycling. Can J Appl Physiol 1997;22:133-47.
    • (1997) Can J Appl Physiol , vol.22 , pp. 133-147
    • Gannon, G.A.1    Rhind, S.G.2    Suzui, M.3    Shek, P.N.4    Shephard, R.J.5
  • 63
    • 2442661489 scopus 로고    scopus 로고
    • Leukocytes, cytokines, growth factors and hormones in human skeletal muscle and blood after uphill or downhill running
    • Malm C, Sjodin TL, Sjoberg B, Lenkei R, Renstrom P, Lundberg IE, et al. Leukocytes, cytokines, growth factors and hormones in human skeletal muscle and blood after uphill or downhill running. J Physiol 2004;556:983-1000.
    • (2004) J Physiol , vol.556 , pp. 983-1000
    • Malm, C.1    Sjodin, T.L.2    Sjoberg, B.3    Lenkei, R.4    Renstrom, P.5    Lundberg, I.E.6
  • 64
    • 33646400540 scopus 로고    scopus 로고
    • Sex-based effects on the distribution of NK cell subsets in response to exercise and carbohydrate intake in adolescents
    • Timmons BW, Tarnopolsky MA, Bar-Or O. Sex-based effects on the distribution of NK cell subsets in response to exercise and carbohydrate intake in adolescents. J Appl Physiol 2006;100:1513-9.
    • (2006) J Appl Physiol , vol.100 , pp. 1513-1519
    • Timmons, B.W.1    Tarnopolsky, M.A.2    Bar-Or, O.3
  • 65
    • 33646522183 scopus 로고    scopus 로고
    • Puberty effects on NK cell responses to exercise and carbohydrate intake in boys
    • Timmons BW, Tarnopolsky MA, Snider DP, Bar-Or O. Puberty effects on NK cell responses to exercise and carbohydrate intake in boys. Med Sci Sports Exerc 2006;38:864-74.
    • (2006) Med Sci Sports Exerc , vol.38 , pp. 864-874
    • Timmons, B.W.1    Tarnopolsky, M.A.2    Snider, D.P.3    Bar-Or, O.4
  • 66
    • 34548263585 scopus 로고    scopus 로고
    • Evidence of sex-based differences in natural killer cell responses to exercise and carbohydrate intake in children
    • Timmons BW, Bar-Or O. Evidence of sex-based differences in natural killer cell responses to exercise and carbohydrate intake in children. Eur J Appl Physiol 2007;101:233-40.
    • (2007) Eur J Appl Physiol , vol.101 , pp. 233-240
    • Timmons, B.W.1    Bar-Or, O.2
  • 67
    • 24644478044 scopus 로고    scopus 로고
    • Analysis of global mRNA expression in human skeletal muscle during recovery from endurance exercise
    • Mahoney DJ, Parise G, Melov S, Safdar A, Tarnopolsky MA. Analysis of global mRNA expression in human skeletal muscle during recovery from endurance exercise. FASEB J 2005;19:1498-500.
    • (2005) FASEB J , vol.19 , pp. 1498-1500
    • Mahoney, D.J.1    Parise, G.2    Melov, S.3    Safdar, A.4    Tarnopolsky, M.A.5
  • 68
    • 8444253252 scopus 로고    scopus 로고
    • CD56bright NK cells are enriched at inflammatory sites and can engage with monocytes in a reciprocal program of activation
    • Dalbeth N, Gundle R, Davies RJ, Lee YC, McMichael AJ, Callan MF. CD56bright NK cells are enriched at inflammatory sites and can engage with monocytes in a reciprocal program of activation. J Immunol 2004;173:6418-26.
    • (2004) J Immunol , vol.173 , pp. 6418-6426
    • Dalbeth, N.1    Gundle, R.2    Davies, R.J.3    Lee, Y.C.4    McMichael, A.J.5    Callan, M.F.6
  • 69
    • 33751527421 scopus 로고    scopus 로고
    • Expression of angiogenic growth factors by uterine natural killer cells during early pregnancy
    • Lash GE, Schiessl B, Kirkley M, Innes BA, Cooper A, Searle RF et al. Expression of angiogenic growth factors by uterine natural killer cells during early pregnancy. J Leukoc Biol 2006;80:572-80.
    • (2006) J Leukoc Biol , vol.80 , pp. 572-580
    • Lash, G.E.1    Schiessl, B.2    Kirkley, M.3    Innes, B.A.4    Cooper, A.5    Searle, R.F.6
  • 70
    • 0023890237 scopus 로고
    • Effect of acute physical exercise on lymphocyte sub-populations in trained and untrained subjects
    • Oshida Y, Yamanouchi K, Hayamizu S, Sato Y. Effect of acute physical exercise on lymphocyte sub-populations in trained and untrained subjects. Int J Sports Med 1988;9:137-40.
    • (1988) Int J Sports Med , vol.9 , pp. 137-140
    • Oshida, Y.1    Yamanouchi, K.2    Hayamizu, S.3    Sato, Y.4
  • 71
    • 0026078727 scopus 로고
    • Biphasic changes in leukocytes induced by strenuous exercise
    • Hansen JB, Wilsgard L, Osterud B. Biphasic changes in leukocytes induced by strenuous exercise. Eur J Appl Physiol 1991;62:157-61.
    • (1991) Eur J Appl Physiol , vol.62 , pp. 157-161
    • Hansen, J.B.1    Wilsgard, L.2    Osterud, B.3
  • 72
    • 34250702678 scopus 로고    scopus 로고
    • Effect of Exercise Intensity on Exercise-Induced Lymphocyte Apoptosis
    • Navalta, JW, Sedlock DA, Park KS. Effect of Exercise Intensity on Exercise-Induced Lymphocyte Apoptosis. Int J Sports Med 2007;28:539-42.
    • (2007) Int J Sports Med , vol.28 , pp. 539-542
    • Navalta, J.W.1    Sedlock, D.A.2    Park, K.S.3
  • 73
  • 75
    • 30344462371 scopus 로고    scopus 로고
    • Effects of exercise intensity on lymphocyte apoptosis induced by oxidative stress in men
    • Jong-Shyan Wang & Yu-Hsiang Huang. Effects of exercise intensity on lymphocyte apoptosis induced by oxidative stress in men. Eur J Appl Physiol 2005;95:290-7.
    • (2005) Eur J Appl Physiol , vol.95 , pp. 290-297
    • Wang, J.-S.1    Huang, Y.-S.2
  • 77
    • 38649129910 scopus 로고    scopus 로고
    • Exercise-induced redistribution of T lymphocytes is regulated by adrenergic mechanisms
    • Kruger K, Lechtermann A, Fobker M, Volker K, Mooren, FC. Exercise-induced redistribution of T lymphocytes is regulated by adrenergic mechanisms. Brain Behave Immun 2008;22:324-38.
    • (2008) Brain Behave Immun , vol.22 , pp. 324-338
    • Kruger, K.1    Lechtermann, A.2    Fobker, M.3    Volker, K.4    Mooren, F.C.5
  • 78
    • 0025947895 scopus 로고
    • CD28 delivers a costimulatory signal involved in antigen-specific IL-2 production by human T cells
    • Jenkins MK, Taylor PS, Norton SD, Urdahl KB. CD28 delivers a costimulatory signal involved in antigen-specific IL-2 production by human T cells. J Immunol 1991;147:2461-6.
    • (1991) J Immunol , vol.147 , pp. 2461-2466
    • Jenkins, M.K.1    Taylor, P.S.2    Norton, S.D.3    Urdahl, K.B.4
  • 79
    • 0026700604 scopus 로고
    • Prolonged IL-2 receptor á/CD25 expression after T cell activation via the adhesion molecules CD2 and CD28. Demonstration of combined transcriptional and posttranscriptional regulation
    • Cerdan C, Martin Y, Courcoul M, Brailly H, Mawas C, Birg F, et al. Prolonged IL-2 receptor á/CD25 expression after T cell activation via the adhesion molecules CD2 and CD28. Demonstration of combined transcriptional and posttranscriptional regulation. J Immunol 1992;149:2255-61.
    • (1992) J Immunol , vol.149 , pp. 2255-2261
    • Cerdan, C.1    Martin, Y.2    Courcoul, M.3    Brailly, H.4    Mawas, C.5    Birg, F.6
  • 80
    • 0026587436 scopus 로고
    • Differential age-change in the numbers of CD4+CD45RA+ and CD4+CD29+ T cell subsets in human peripheral blood
    • Utsuyama M, Hirokawa K, Kurashima C, Fukayama M, Inamatsu T, Suzuki K et al. Differential age-change in the numbers of CD4+CD45RA+ and CD4+CD29+ T cell subsets in human peripheral blood. Mech Ageing Dev 1992;63:57-68.
    • (1992) Mech Ageing Dev , vol.63 , pp. 57-68
    • Utsuyama, M.1    Hirokawa, K.2    Kurashima, C.3    Fukayama, M.4    Inamatsu, T.5    Suzuki, K.6
  • 81
    • 62849095175 scopus 로고    scopus 로고
    • Effect of moderate exercise training on T-helper cell subpopulations in elderly people
    • Shimizu K, Kimura F, Akimoto T, Akama T, Tanabe K, Nishijima, et al. Effect of moderate exercise training on T-helper cell subpopulations in elderly people. Exerc Immunol Rew 2008;14:24-37.
    • (2008) Exerc Immunol Rew , vol.14 , pp. 24-37
    • Shimizu, K.1    Kimura, F.2    Akimoto, T.3    Akama, T.4    Tanabe, K.5    Nishijima6
  • 83
    • 13744252785 scopus 로고    scopus 로고
    • Reversing age-associated immunosenescence via exercise
    • Kohut ML, Senchina, DS. Reversing age-associated immunosenescence via exercise. Exerc Immunol Rev 2004;10:6-41.
    • (2004) Exerc Immunol Rev , vol.10 , pp. 6-41
    • Kohut, M.L.1    Senchina, D.S.2
  • 84
    • 0020522413 scopus 로고
    • Endogenous pyrogen activity in human plasma after exercise
    • Cannon JG, Kluger MJ. Endogenous pyrogen activity in human plasma after exercise. Sci 1983;220:617-9.
    • (1983) Sci , vol.220 , pp. 617-619
    • Cannon, J.G.1    Kluger, M.J.2
  • 85
    • 0025874392 scopus 로고
    • Immunologic mediators as parameters of the reaction to strenuous exercise
    • Northoff H, Berg A. Immunologic mediators as parameters of the reaction to strenuous exercise. Int J Sports Med 1991;12:9-15.
    • (1991) Int J Sports Med , vol.12 , pp. 9-15
    • Northoff, H.1    Berg, A.2
  • 87
    • 77956335194 scopus 로고    scopus 로고
    • Interleukin-6 signaling in liver-parenchymal cells suppresses hepatic inflammation and improves systemic insulin action
    • Wunderlich FT, Strohle P, Konner AC, Gruber S, Tovar S, Bronneke HS, et al. Interleukin-6 signaling in liver-parenchymal cells suppresses hepatic inflammation and improves systemic insulin action. Cell Metab 2010;12:237-49.
    • (2010) Cell Metab , vol.12 , pp. 237-249
    • Wunderlich, F.T.1    Strohle, P.2    Konner, A.C.3    Gruber, S.4    Tovar, S.5    Bronneke, H.S.6
  • 88
    • 77949317183 scopus 로고    scopus 로고
    • IL-15 prevents apoptosis, reverses innate and adaptive immune dysfunction, and improves survival in sepsis
    • Inoue S, Unsinger J, Davis CG, Muenzer JT, Ferguson TA, Chang K, et al. IL-15 prevents apoptosis, reverses innate and adaptive immune dysfunction, and improves survival in sepsis. J Immunol 2010;184:1401-9.
    • (2010) J Immunol , vol.184 , pp. 1401-1409
    • Inoue, S.1    Unsinger, J.2    Davis, C.G.3    Muenzer, J.T.4    Ferguson, T.A.5    Chang, K.6
  • 89
    • 79953307941 scopus 로고    scopus 로고
    • Upregulation of circulating IL-15 by treadmill running in healthy individuals: Is IL 15 an endocrine mediator of the beneficial effects of endurance exercise?
    • Tamura Y, Watanabe K, Kantani T, Hayashi J, Ishida N, Kaneki M. Upregulation of circulating IL-15 by treadmill running in healthy individuals: Is IL 15 an endocrine mediator of the beneficial effects of endurance exercise? Endocr J 2011;58:211-5.
    • (2011) Endocr J , vol.58 , pp. 211-215
    • Tamura, Y.1    Watanabe, K.2    Kantani, T.3    Hayashi, J.4    Ishida, N.5    Kaneki, M.6
  • 90
    • 1542468712 scopus 로고    scopus 로고
    • Exhaustive exercise and type-1/ type-2 cytokine balance with special focus on interleukin-12 p40/p70
    • Suzuki K, Nakaji S, Kurakake S, Totsuka M, Sato K, Kuriyama T, et al. Exhaustive exercise and type-1/ type-2 cytokine balance with special focus on interleukin-12 p40/p70. Exerc Immunol Rev 2003;9:48-57.
    • (2003) Exerc Immunol Rev , vol.9 , pp. 48-57
    • Suzuki, K.1    Nakaji, S.2    Kurakake, S.3    Totsuka, M.4    Sato, K.5    Kuriyama, T.6
  • 91
    • 13744250302 scopus 로고    scopus 로고
    • Changes in inflammatory mediators following eccentric exercise of the elbow flexors
    • Hirose L, Nosaka K, Newton M, Laveder A, Kano M, Peake JM, et al. Changes in inflammatory mediators following eccentric exercise of the elbow flexors. Exerc Immunol Rev 2004;10:75-90.
    • (2004) Exerc Immunol Rev , vol.10 , pp. 75-90
    • Hirose, L.1    Nosaka, K.2    Newton, M.3    Laveder, A.4    Kano, M.5    Peake, J.M.6
  • 92
    • 12144287060 scopus 로고    scopus 로고
    • Influence of carbohydrate ingestion on immune changes after 2 h of intensive resistance training
    • Nieman DC, Davis JM, Brown VA, Henson DA, Dumke CL, Utter AC, et al. Influence of carbohydrate ingestion on immune changes after 2 h of intensive resistance training. J Appl Physiol 2004;96:1292-8.
    • (2004) J Appl Physiol , vol.96 , pp. 1292-1298
    • Nieman, D.C.1    Davis, J.M.2    Brown, V.A.3    Henson, D.A.4    Dumke, C.L.5    Utter, A.C.6
  • 94
    • 15444374348 scopus 로고    scopus 로고
    • The anti-infammatory effect of exercise
    • Petersen AM, Pedersen BK. The anti-infammatory effect of exercise. J Appl Physiol 2005;98:1154-62.
    • (2005) J Appl Physiol , vol.98 , pp. 1154-1162
    • Petersen, A.M.1    Pedersen, B.K.2
  • 95
    • 0031736326 scopus 로고    scopus 로고
    • Increased circulating cytokine receptors and ex vivo interleukin-1 receptor antagonist and interleukin1b production but decreased tumour necrosis factor-a production after a 5-km run
    • Drenth JP, Krebbers RJ, Bijzet J, van der Meer JW. Increased circulating cytokine receptors and ex vivo interleukin-1 receptor antagonist and interleukin1b production but decreased tumour necrosis factor-a production after a 5-km run. Eur J Clin Invest 1998;28:866-72.
    • (1998) Eur J Clin Invest , vol.28 , pp. 866-872
    • Drenth, J.P.1    Krebbers, R.J.2    Bijzet, J.3    van der Meer, J.W.4
  • 96
    • 0033771019 scopus 로고    scopus 로고
    • Exercise elevates plasma levels but not gene expression of IL-1b, IL-6, and TNF-α in blood mononuclear cells
    • Moldoveanu AI, Shephard RJ, Shek PN. Exercise elevates plasma levels but not gene expression of IL-1b, IL-6, and TNF-α in blood mononuclear cells. J Appl Physiol 2000;89:1499-504.
    • (2000) J Appl Physiol , vol.89 , pp. 1499-1504
    • Moldoveanu, A.I.1    Shephard, R.J.2    Shek, P.N.3
  • 98
    • 25644446872 scopus 로고    scopus 로고
    • Physical activity and modulation of systemic low-level inflammation
    • Bruunsgaard H. Physical activity and modulation of systemic low-level inflammation. J Leuk Biol 2005;78:819-35.
    • (2005) J Leuk Biol , vol.78 , pp. 819-835
    • Bruunsgaard, H.1
  • 101
    • 0041677606 scopus 로고    scopus 로고
    • Principles of interleukin (IL)-6-type cytokine signalling and its regulation
    • Peter C. Heinrich, Iris Behrmann, Serge Haan, Heike M. Hermanns, Gerhard Muller-Newen & Fred Schaper. Principles of interleukin (IL)-6-type cytokine signalling and its regulation. Biochem J 2003;374:1-20.
    • (2003) Biochem J , vol.374 , pp. 1-20
    • Peter, C.1    Heinrich, I.B.2    Haan, S.3    Hermanns, H.M.4    Muller-Newen, G.5    Schaper, F.6
  • 102
    • 77957958068 scopus 로고    scopus 로고
    • The effect of exercise on plasma soluble IL-6 receptor concentration: A dichotomous response
    • Robson-Ansley P, Cockburn E, Walshe I, Stevenson E, Nimmo M. The effect of exercise on plasma soluble IL-6 receptor concentration: a dichotomous response. Exerc Immunol Rev 2010;16:56-76
    • (2010) Exerc Immunol Rev , vol.16 , pp. 56-76
    • Robson-Ansley, P.1    Cockburn, E.2    Walshe, I.3    Stevenson, E.4    Nimmo, M.5
  • 103
    • 32044465506 scopus 로고    scopus 로고
    • TOR signaling in growth and metabolism
    • Wullschleger S, et al. TOR signaling in growth and metabolism. Cell 2006;124:471-84.
    • (2006) Cell , vol.124 , pp. 471-484
    • Wullschleger, S.1
  • 104
    • 34547907805 scopus 로고    scopus 로고
    • Expanding mTOR signaling
    • Yang Q, Guan KL. Expanding mTOR signaling. Cell Res 2007;17:666-81.
    • (2007) Cell Res , vol.17 , pp. 666-681
    • Yang, Q.1    Guan, K.L.2
  • 106
    • 54949109311 scopus 로고    scopus 로고
    • The TSC-mTOR signaling pathway regulates the innate inflammatory response
    • Weichhart T, et al. The TSC-mTOR signaling pathway regulates the innate inflammatory response. Immun 2008;29:565-77.
    • (2008) Immun , vol.29 , pp. 565-577
    • Weichhart, T.1


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