Identifying key juxtamembrane interactions in cell membranes using AraC-based transcriptional reporter assay (AraTM)

Journal of Biological Chemistry

Volumn 287, Issue 37, 2012, Pages 31515-31526

  Su, Pin Chuan ^a   Berger, Bryan W ^a  

^a Lehigh University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCTS; BACTERIAL MEMBRANES; CONSTITUTIVELY ACTIVES; EXTRACELLULAR; HEK293 CELLS; HOMODIMERIZATION; INTEGRINS; INTRACELLULAR SIGNALING; LIGAND BINDING; LIGAND RECOGNITION; MEMBRANE TRAFFICKING; REGULATORY MECHANISM; REPORTER ASSAY; REVERSE ORIENTATION; SPECIFIC INTERACTION; SPECIFIC INTERFACE; TRANSMEMBRANES; WILD TYPES;

CELL MEMBRANES; CHEMICAL ACTIVATION; CYTOLOGY; DIMERIZATION; LIGANDS; SIGNAL TRANSDUCTION;

MEMBRANES;

ADVANCED GLYCATION END PRODUCT; ARAC PROTEIN;

ARTICLE; BACTERIAL MEMBRANE; CELL ASSAY; CELL INTERACTION; CELL MEMBRANE; CONTROLLED STUDY; DIMERIZATION; EXTRACELLULAR SPACE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; JUXTAMEMBRANE; MEMBRANE TRANSPORT; MOLECULAR RECOGNITION; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION REPORTER ASSAY;

ARAC TRANSCRIPTION FACTOR; CELL MEMBRANE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENES, REPORTER; HUMANS; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RECEPTORS, IMMUNOLOGIC; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION;

ARA; BACTERIA (MICROORGANISMS);

EID: 84866076617     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.396895     Document Type: Article

References (40)

1. Klemm, J. D., Schreiber, S. L., and Crabtree, G. R. (1998) Dimerization as a regulatory mechanism in signal transduction. Annu. Rev. Immunol. 16, 569-592
2. Moore, D. T., Berger, B. W., and DeGrado, W. F. (2008) Protein-protein interactions in the membrane: sequence, structural, and biological motifs. Structure 16, 991-1001
3. Bennett, J. S. (2005) Structure and function of the platelet integrin αIIbβ3. J. Clin. Investig. 115, 3363-3369
4. Li, W., Metcalf, D. G., Gorelik, R., Li, R., Mitra, N., Nanda, V., Law, P. B., Lear, J. D., Degrado, W. F., and Bennett, J. S. (2005) A push-pull mechanism for regulating integrin function. Proc. Natl. Acad. Sci. U.S.A. 102, 1424-1429
5. Metcalf, D. G., Kulp, D. W., Bennett, J. S., and DeGrado, W. F. (2009) Multiple approaches converge on the structure of the integrin αIIb/β3 transmembrane heterodimer. J. Mol. Biol. 392, 1087-1101
6. Li, R., Babu, C. R., Lear, J. D., Wand, A. J., Bennett, J. S., and DeGrado, W. F. (2001) Oligomerization of the integrin αIIbβ3: roles of the transmembrane and cytoplasmic domains. Proc. Natl. Acad. Sci. U.S.A. 98, 12462-12467
7. Berger, B. W., Kulp, D. W., Span, L. M., DeGrado, J. L., Billings, P. C., Senes, A., Bennett, J. S., and DeGrado, W. F. (2010) Consensus motif for integrin transmembrane helix association. Proc. Natl. Acad. Sci. U.S.A. 107, 703-708
8. Mo, X., Luo, S. Z., López, J. A., and Li, R. (2008) Juxtamembrane basic residues in glycoprotein Ibβ cytoplasmic domain are required for assembly and surface expression of glycoprotein Ib-IX complex. FEBS Lett. 582, 3270-3274
9. Mo, X., Luo, S. Z., Munday, A. D., Sun, W., Berndt, M. C., López, J. A., Dong, J. F., and Li, R. (2008) The membrane-proximal intermolecular disulfide bonds in glycoprotein Ib influence receptor binding to von Willebrand factor. J. Thrombosis Haemostasis 6, 1789-1795
10. Oates, J., King, G., and Dixon, A. M. (2010) Strong oligomerization behavior of PDGFβ receptor transmembrane domain and its regulation by the juxtamembrane regions. Biochim. Biophys. Acta 1798, 605-615
11. Schneider, D., and Engelman, D. M. (2003) GALLEX, a measurement of heterologous association of transmembrane helices in a biological membrane. J. Biol. Chem. 278, 3105-3111
12. Russ, W. P., and Engelman, D. M. (1999) TOXCAT: a measure of transmembrane helix association in a biological membrane. Proc. Natl. Acad. Sci. U.S.A. 96, 863-868
13. Gurezka, R., and Langosch, D. (2001) In vitro selection of membrane-spanning leucine zipper protein-protein interaction motifs using POSSYCCAT. J. Biol. Chem. 276, 45580-45587
14. Roth, L., Nasarre, C., Dirrig-Grosch, S., Aunis, D., Crémel, G., Hubert, P., and Bagnard, D. (2008) Transmembrane domain interactions control biological functions of neuropilin-1. Mol. Biol. Cell 19, 646-654
15. Ladant, D., and Karimova, G. (2000) Genetic systems for analyzing protein-protein interactions in bacteria. Res. Microbiol. 151, 711-720
16. DiRita, V. J. (1992) Co-ordinate expression of virulence genes by ToxR in V. cholerae. Mol. Microbiol. 6, 451-458
17. Ott, C. M., and Lingappa, V. R. (2002) Integral membrane protein biosynthesis: why topology is hard to predict. J. Cell Sci. 115, 2003-2009
18. Kolmar, H., Hennecke, F., Götze, K., Janzer, B., Vogt, B., Mayer, F., and Fritz, H. J. (1995) Membrane insertion of the bacterial signal transduction protein ToxR and requirements of transcription activation studied by modular replacement of different protein substructures. EMBO J. 14, 3895-3904
19. Bustos, S. A., and Schleif, R. F. (1993) Functional domains of the AraC protein. Proc. Natl. Acad. Sci. U.S.A. 90, 5638-5642
20. Siegele, D. A., and Hu, J. C. (1997) Gene expression from plasmids containing the araBAD promoter at subsaturating inducer concentrations represents mixed populations. Proc. Natl. Acad. Sci. U.S.A. 94, 8168-8172
21. Bonde, M. M., Hansen, J. T., Sanni, S. J., Hauns, S., Gammeltoft, S., Lyngs, C., and Hansen, J. L. (2010) Biased signaling of the angiotensin II type 1 receptor can be mediated through distinct mechanisms. PLoS ONE 5
22. Schleif, R. (2003) AraC protein: a love-hate relationship. BioEssays 25, 274-282
23. Weldon, J. E., and Schleif, R. F. (2006) Specific interactions by the N-terminal arm inhibit self-association of the AraC dimerization domain. Protein Science 15, 2828-2835
24. Eustance, R., and Schleif, R. (1996) In vivo association of protein fragments giving active AraC. Proteins-Structure Function Bioinformatics 25, 501-505
25. Nikaido, H. (1994) Maltose transport system of E. coli: an ABC-type transporter. FEBS Lett. 346, 55-58
26. Li, R., Gorelik, R., Nanda, V., Law, P. B., Lear, J. D., DeGrado, W. F., and Bennett, J. S. (2004) Dimerization of the transmembrane domain of Integrin αIIb subunit in cell membranes. J. Biol. Chem. 279, 26666-26673
27. Schneider, D., and Engelman, D. (2004) Involvement of transmembrane domain interactions in signal transduction by α/β integrins. J. Biol. Chem. 279, 9840-9846
28. Schmidt, A. M., Yan, S. D., Yan, S. F., and Stern, D. M. (2001) The multi-ligand receptor RAGE as a progression factor amplifying immune and inflammatory responses. J. Clin. Investig. 108, 949-955
29. Hofmann, M. A., Drury, S., Fu, C., Qu, W., Taguchi, A., Lu, Y., Avila, C., Kambham, N., Bierhaus, A., Nawroth, P., Neurath, M. F., Slattery, T., Beach, D., McClary, J., Nagashima, M., Morser, J., Stern, D., and Schmidt, A. M. (1999) RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides. Cell 97, 889-901
30. Ostendorp, T., Leclerc, E., Galichet, A., Koch, M., Demling, N., Weigle, B., Heizmann, C. W., Kroneck, P. M., and Fritz, G. (2007) Structural and functional insights into RAGE activation by multimeric S100B. EMBO J. 26, 3868-3878
31. Zong, H., Madden, A., Ward, M., Mooney, M. H., Elliott, C. T., and Stitt, A. W. (2010) Homodimerization is essential for the receptor for advanced glycation end products (RAGE)-mediated signal transduction. J. Biol. Chem. 285, 23137
32. Xie, J., Burz, D. S., He, W., Bronstein, I. B., Lednev, I., and Shekhtman, A. (2007) Hexameric calgranulin C (S100A12) binds to the receptor for advanced glycated end products (RAGE) using symmetric hydrophobic target-binding patches. J. Biol. Chem. 282, 4218-4231
33. Ramsay, D., Kellett, E., McVey, M., Rees, S., and Milligan, G. (2002) Homoand hetero-oligomeric interactions between G-protein-coupled receptors in living cells monitored by two variants of bioluminescence resonance energy transfer (BRET): hetero-oligomers between receptor subtypes form more efficiently than between less closely related sequences. Biochem. J. 365, 429-440
34. Buensuceso, C. (2003) Detection of integrin αIIbβ3 clustering in living cells. J Biol. Chem. 278, 15217-15224
35. Xie, J., Reverdatto, S., Frolov, A., Hoffmann, R., Burz, D. S., and Shekhtman, A. (2008) Structural basis for pattern recognition by the receptor for advanced glycation end products (RAGE). J. Biol. Chem. 283, 27255-27269
36. Duong, M. T., Jaszewski, T. M., Fleming, K. G., and MacKenzie, K. R. (2007) Changes in apparent free energy of helix-helix dimerization in a biological membrane due to point mutations. J. Mol. Biol. 371, 422-434
37. Rai, V., Maldonado, A. Y., Burz, D. S., Reverdatto, S., Yan, S. F., Schmidt, A. M., and Shekhtman, A. (2012) Signal transduction in receptor for advanced glycation end products (RAGE): solution structure of C-terminal rage (ctRAGE) and its binding to mDia1. J. Biol. Chem. 287, 5133-5144
38. Scartezzini, P., Egeo, A., Colella, S., Fumagalli, P., Arrigo, P., Nizetic, D., Taramelli, R., and Rasore-Quartino, A. (1997) Cloning a new human gene from chromosome 21q22.3 encoding a glutamic acid-rich protein expressed in heart and skeletal muscle. Human Genetics 99, 387-392
39. 2+ to glutamic acid-rich polypeptides from the rod outer segment. Biophys. J. 92, 3207-3214
40. Karimova, G., Pidoux, J., Ullmann, A., and Ladant, D. (1998) A bacterial two-hybrid system based on a reconstituted signal transduction pathway. Proc. Natl. Acad. Sci. U.S.A. 95, 5752-5756