The membrane-proximal intermolecular disulfide bonds in glycoprotein Ib influence receptor binding to von Willebrand factor

Journal of Thrombosis and Haemostasis

Volumn 6, Issue 10, 2008, Pages 1789-1795

  Mo, X ^a   Luo, S Z ^a   Munday, A D ^b   Sun, W ^c   Berndt, M C ^d   Lopez J A ^b   Dong, J F ^c   Li, Renhao ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d MONASH UNIVERSITY   (Australia)

Author keywords

GPIb IX; Inside out regulation; Membrane proximal disulfide bonds; VWF binding

Indexed keywords

BLOOD CLOTTING FACTOR 9; CYSTEINE; GLYCOPROTEIN IB; GLYCOPROTEIN IB ALPHA; GLYCOPROTEIN IB BETA; RISTOCETIN; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR;

ANIMAL CELL; ARTICLE; CELL LINE; CHO CELL; CONTROLLED STUDY; COVALENT BOND; DISULFIDE BOND; GENE MUTATION; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INTERACTION; RECEPTOR BINDING; WILD TYPE;

ANIMALS; BINDING SITES; CHO CELLS; CRICETINAE; CRICETULUS; CYSTEINE; DISULFIDES; HUMANS; MUTANT PROTEINS; PERFUSION; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN SUBUNITS; TRANSFECTION; VON WILLEBRAND FACTOR;

EID: 52449117744     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2008.03088.x     Document Type: Article

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