메뉴 건너뛰기




Volumn 94, Issue 10, 2012, Pages 2111-2115

Leptin and leptin receptor-related monogenic obesity

Author keywords

Early onset obesity; Hypogonadotrophic hypogonadism; Leptin

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CILIARY NEUROTROPHIC FACTOR; LEPTIN; LEPTIN RECEPTOR; MELANOCORTIN 4 RECEPTOR; PROOPIOMELANOCORTIN; RECOMBINANT LEPTIN; STAT3 PROTEIN;

EID: 84866074838     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2012.05.010     Document Type: Review
Times cited : (84)

References (36)
  • 1
    • 31544432529 scopus 로고    scopus 로고
    • Melanocortin-4 receptors, β-MSH and leptin: Key elements in the satiety pathway
    • DOI 10.1016/j.peptides.2005.01.030, PII S0196978105004481, The Melanocortin Pathway 2005 Part II
    • J.A. Harrold, and G. Williams Melanocortin-4 receptors, beta-MSH and leptin: key elements in the satiety pathway Peptides 27 2006 365 371 (Pubitemid 43162907)
    • (2006) Peptides , vol.27 , Issue.2 , pp. 365-371
    • Harrold, J.A.1    Williams, G.2
  • 3
    • 0032014836 scopus 로고    scopus 로고
    • A leptin missense mutation associated with hypogonadism and morbid obesity
    • A. Strobel, T. Issad, L. Camoin, M. Ozata, and A.D. Strosberg A leptin missense mutation associated with hypogonadism and morbid obesity Nat. Genet. 18 1998 213 215
    • (1998) Nat. Genet. , vol.18 , pp. 213-215
    • Strobel, A.1    Issad, T.2    Camoin, L.3    Ozata, M.4    Strosberg, A.D.5
  • 5
    • 67649908458 scopus 로고    scopus 로고
    • A novel homozygous missense mutation of the leptin gene (N103K) in an obese Egyptian patient
    • I. Mazen, M. El-Gammal, M. Abdel-Hamid, and K. Amr A novel homozygous missense mutation of the leptin gene (N103K) in an obese Egyptian patient Mol. Genet. Metab. 97 2009 305 308
    • (2009) Mol. Genet. Metab. , vol.97 , pp. 305-308
    • Mazen, I.1    El-Gammal, M.2    Abdel-Hamid, M.3    Amr, K.4
  • 8
    • 79952631516 scopus 로고    scopus 로고
    • Homozygosity for a novel missense mutation in the leptin receptor gene (P316T) in two Egyptian cousins with severe early onset obesity
    • I. Mazen, M. El-Gammal, M. Abdel-Hamid, I.S. Farooqi, and K. Amr Homozygosity for a novel missense mutation in the leptin receptor gene (P316T) in two Egyptian cousins with severe early onset obesity Mol. Genet. Metab. 102 2011 461 464
    • (2011) Mol. Genet. Metab. , vol.102 , pp. 461-464
    • Mazen, I.1    El-Gammal, M.2    Abdel-Hamid, M.3    Farooqi, I.S.4    Amr, K.5
  • 9
    • 0028139089 scopus 로고
    • Positional cloning of the mouse obese gene and its human homologue
    • DOI 10.1038/372425a0
    • Y. Zhang, R. Proenca, M. Maffei, M. Barone, L. Leopold, and J.M. Friedman Positional cloning of the mouse obese gene and its human homologue Nature 372 1994 425 432 (Pubitemid 24365442)
    • (1994) Nature , vol.372 , Issue.6505 , pp. 425-432
    • Zhang, Y.1    Proenca, R.2    Maffei, M.3    Barone, M.4    Leopold, L.5    Friedman, J.M.6
  • 11
    • 6344221594 scopus 로고    scopus 로고
    • Congenital leptin deficiency due to homozygosity for the Δ133G mutation: Report of another case and evaluation of response to four years of leptin therapy
    • DOI 10.1210/jc.2004-0376
    • W.T. Gibson, I.S. Farooqi, M. Moreau, A.M. DePaoli, E. Lawrence, S. O'Rahilly, and R.A.Trussell Congenital leptin deficiency due to homozygosity for the Delta133G mutation: report of another case and evaluation of response to four years of leptin therapy J. Clin. Endocrinol. Metab. 89 2004 4821 4826 (Pubitemid 39391413)
    • (2004) Journal of Clinical Endocrinology and Metabolism , vol.89 , Issue.10 , pp. 4821-4826
    • Gibson, W.T.1    Farooqi, I.S.2    Moreau, M.3    DePaoli, A.M.4    Lawrence, E.5    O'Rahilly, S.6    Trussell, R.A.7
  • 12
    • 0033304576 scopus 로고    scopus 로고
    • Human leptin deficiency caused by a missense mutation: Multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin-mediated defects
    • M. Ozata, I.C. Ozdemir, and J. Licinio Human leptin deficiency caused by a missense mutation: multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin-mediated defects J. Clin. Endocrinol. Metab. 84 1999 3686 3695 (Pubitemid 30645226)
    • (1999) Journal of Clinical Endocrinology and Metabolism , vol.84 , Issue.10 , pp. 3686-3695
    • Ozata, M.1    Ozdemir, I.C.2    Licinio, J.3
  • 13
    • 14544272858 scopus 로고    scopus 로고
    • Monogenic obesity in humans
    • DOI 10.1146/annurev.med.56.062904.144924
    • I.S. Farooqi, and S. O'Rahilly Monogenic obesity in humans Annu. Rev. Med. 56 2005 443 458 (Pubitemid 40299792)
    • (2005) Annual Review of Medicine , vol.56 , pp. 443-458
    • Farooqi, I.S.1    O'Rahilly, S.2
  • 14
    • 33847038657 scopus 로고    scopus 로고
    • Genetic factors in human obesity
    • I.S. Farooqi, and S. O'Rahilly Genetic factors in human obesity Obes. Rev. 8 2007 37 40
    • (2007) Obes. Rev. , vol.8 , pp. 37-40
    • Farooqi, I.S.1    O'Rahilly, S.2
  • 16
    • 0032200002 scopus 로고    scopus 로고
    • Development of food acceptance patterns in the first years of life
    • L.L. Birch Development of food acceptance patterns in the first years of life Proc. Nutr. Soc. 57 1998 617 624 (Pubitemid 128737136)
    • (1998) Proceedings of the Nutrition Society , vol.57 , Issue.4 , pp. 617-624
    • Birch, L.L.1
  • 17
    • 18944376436 scopus 로고    scopus 로고
    • Behavior and lifestyle: Approaches to treatment of obesity
    • D.A. Williamson, and T.M. Stewart Behavior and lifestyle: approaches to treatment of obesity J. La. State Med. Soc. 157 2005 S50 S55
    • (2005) J. La. State Med. Soc. , vol.157
    • Williamson, D.A.1    Stewart, T.M.2
  • 19
    • 84858240310 scopus 로고    scopus 로고
    • Pregnancy in a woman with a leptin-receptor mutation
    • J. Nizard, M. Dommergue, and K. Clement Pregnancy in a woman with a leptin-receptor mutation N. Engl. J. Med. 366 2012 1064 1065
    • (2012) N. Engl. J. Med. , vol.366 , pp. 1064-1065
    • Nizard, J.1    Dommergue, M.2    Clement, K.3
  • 21
    • 0042665945 scopus 로고    scopus 로고
    • Axokine (Regeneron)
    • A. Preti Axokine (Regeneron) I. Drugs 6 2003 696 701
    • (2003) I. Drugs , vol.6 , pp. 696-701
    • Preti, A.1
  • 24
    • 25144478801 scopus 로고    scopus 로고
    • Gene polymorphisms and their effects in the melanocortin system
    • DOI 10.1016/j.peptides.2004.12.031, PII S0196978105002731, The Melanocortin Pathway 2005
    • L. Carroll, J. Voisey, and A. van Daal Gene polymorphisms and their effects in the melanocortin system Peptides 26 2005 1871 1885 (Pubitemid 41354546)
    • (2005) Peptides , vol.26 , Issue.10 , pp. 1871-1885
    • Carroll, L.1    Voisey, J.2    Van Daal, A.3
  • 25
    • 38349151344 scopus 로고    scopus 로고
    • Mutational analysis of the pro-opiomelanocortin gene in French obese children led to the identification of a novel deleterious heterozygous mutation located in the alpha-melanocyte stimulating hormone domain
    • B. Dubern, C. Lubrano-Berthelier, M. Mencarelli, B. Ersoy, M.L. Frelut, D. Bougle, B. Costes, C. Simon, P. Tounian, and C. Vaisse Mutational analysis of the pro-opiomelanocortin gene in French obese children led to the identification of a novel deleterious heterozygous mutation located in the alpha-melanocyte stimulating hormone domain Pediatr. Res. 63 2008 211 216
    • (2008) Pediatr. Res. , vol.63 , pp. 211-216
    • Dubern, B.1    Lubrano-Berthelier, C.2    Mencarelli, M.3    Ersoy, B.4    Frelut, M.L.5    Bougle, D.6    Costes, B.7    Simon, C.8    Tounian, P.9    Vaisse, C.10
  • 27
    • 0034016043 scopus 로고    scopus 로고
    • Profound obesity associated with a balanced translocation that disrupts the SIM1 gene
    • J.L. Holder Jr., N.F. Butte, and A.R. Zinn Profound obesity associated with a balanced translocation that disrupts the SIM1 gene Hum. Mol. Genet. 9 2000 101 108 (Pubitemid 30145294)
    • (2000) Human Molecular Genetics , vol.9 , Issue.1 , pp. 101-108
    • Holder Jr., J.L.1    Butte, N.F.2    Zinn, A.R.3
  • 29
    • 33748746056 scopus 로고    scopus 로고
    • SIM1 overexpression partially rescues agouti yellow and diet-induced obesity by normalizing food intake
    • DOI 10.1210/en.2006-0453
    • B.M. Kublaoui, J.L. Holder Jr., K.P. Tolson, T. Gemelli, and A.R. Zinn SIM1 overexpression partially rescues agouti yellow and diet-induced obesity by normalizing food intake Endocrinology 147 2006 4542 4549 (Pubitemid 44402157)
    • (2006) Endocrinology , vol.147 , Issue.10 , pp. 4542-4549
    • Kublaoui, B.M.1    Holder Jr., J.L.2    Tolson, K.P.3    Gemelli, T.4    Zinn, A.R.5
  • 30
    • 0034653422 scopus 로고    scopus 로고
    • BDNF regulates eating behavior and locomotor activity in mice
    • S.G. Kernie, D.J. Liebl, and L.F. Parada BDNF regulates eating behavior and locomotor activity in mice EMBO. J. 19 2000 1290 1300 (Pubitemid 30151025)
    • (2000) EMBO Journal , vol.19 , Issue.6 , pp. 1290-1300
    • Kernie, S.G.1    Liebl, D.J.2    Parada, L.F.3
  • 31
    • 0038392755 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor
    • DOI 10.1038/nn1073
    • B. Xu, E.H. Goulding, K. Zang, D. Cepoi, R.D. Cone, K.R. Jones, L.H. Tecott, and L.F. Reichardt Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor Nat. Neurosci. 6 2003 736 742 (Pubitemid 36792889)
    • (2003) Nature Neuroscience , vol.6 , Issue.7 , pp. 736-742
    • Xu, B.1    Goulding, E.H.2    Zang, K.3    Cepoi, D.4    Cone, R.D.5    Jones, K.R.6    Tecott, L.H.7    Reichardt, L.F.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.