Continuous twin screw granulation: Influence of process variables on granule and tablet quality

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 82, Issue 1, 2012, Pages 205-211

  Vercruysse, J ^a   Cordoba Diaz D ^b   Peeters, E ^a   Fonteyne, M ^a   Delaet, U ^c   Van Assche, I ^c   De Beer, T ^a   Remon, J P ^a   Vervaet, C ^a  

^a GHENT UNIVERSITY   (Belgium)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^c JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

Author keywords

Continuous wet granulation; Experimental design; Granule and tablet quality; Process variables; Twin screw granulation

Indexed keywords

THEOPHYLLINE;

ARTICLE; DRUG GRANULATION; DRUG GRANULE; DRUG SOLUBILITY; PARTICLE SIZE; TABLET COMPRESSION; TABLET DISINTEGRATION TIME; TABLET FRIABILITY; TABLET POROSITY; TABLET PROPERTY; TEMPERATURE; TENSILE STRENGTH; TORQUE; TWIN SCREW GRANULATION;

DRUG COMPOUNDING; EXCIPIENTS; LACTOSE; PARTICLE SIZE; POROSITY; POVIDONE; SOLUBILITY; TABLETS; TEMPERATURE; TENSILE STRENGTH; THEOPHYLLINE;

EID: 84866043170     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2012.05.010     Document Type: Article

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