Correlation between the cord vitamin D levels and regulatory T cells in newborn infants

European Journal of Pediatrics

Volumn 171, Issue 8, 2012, Pages 1161-1166

  Tarcan, Aylin ^a   Güven, Ayşegül ^a   Ecevit, Ayşe ^a   Sözer, Oktay ^a   Tarcan, Aytül ^b   Özbek, Namýk ^a  

^a BASKENT UNIVERSITY   (Turkey)

^b Etlik Maternity Hospital   (Turkey)

Author keywords

Cord blood; Newborn; Regulatory tcells; Vitamin D

Indexed keywords

25 HYDROXYVITAMIN D;

FLOW CYTOMETRY; HELPER CELL; HUMAN; INFANT; LEUKOCYTE COUNT; LYMPHOCYTE COUNT; NEWBORN; NORMAL HUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; REVIEW; UMBILICAL CORD BLOOD; VITAMIN BLOOD LEVEL;

BIOLOGICAL MARKERS; FETAL BLOOD; FLOW CYTOMETRY; HUMANS; INFANT, NEWBORN; LYMPHOCYTE COUNT; T-LYMPHOCYTES, REGULATORY; VITAMIN D; VITAMIN D DEFICIENCY;

EID: 84866020743     PISSN: 03406199     EISSN: 14321076     Source Type: Journal    
DOI: 10.1007/s00431-012-1688-6     Document Type: Review

References (36)

1. Borrego LM, Arroz MJ, Videira P, Martins C, Guimaraes H, Nunes G, Papoila AL, Trindade H (2009) Regulatory cells, cytokine pattern and clinical risk factors for asthma in infants and young children with recurrent wheeze. Clin Exp Allergy 39:1160-1169
2. Bouillon R, Carmeliet G, Daci E, Segaert S, Verstuyf A (1998) Vitamin D metabolism and action. Osteoporos Int 8:S13-S19 (Pubitemid 28416850)
3. Bowyer L, Catling-Paull C, Diamond T, Homer C, Davis G, Craig ME (2009) Vitamin D, PTH and calcium levels in pregnant women and their neonates. Clin Endocrinol (Oxf) 70:372-377
4. Bystry RS, Aluvihare V, Welch KA, Kallikourdis M, Betz AG (2001) B cells and professional APCs recruit regulatory T cells via CCL4. Nat Immunol 2:1126-1132 (Pubitemid 33130146)
5. Cakmak FN, Erol M, Ergül P, Yalcyner A (1997) T lymphocytes and vitamins. J Pediatr 130:77-85
6. Cohen JL, Trenado A, Vasey D, Klatzmann D, Salomon BL (2002) CD4 (+) CD25 (+) immunoregulatory T cells: new therapeutics for graft-versus-host disease. J Exp Med 196:401-406 (Pubitemid 34875668)
7. DeLuca HF, Cantorna MT (2001) Vitamin D: its role and uses in immunology. FASEB J 15:2579-2585 (Pubitemid 33131084)
8. DeLucia M, Carpenter T (2000) Rickets in the sunshine? Nutrition 8:97-98
9. Ellman P, Anderson KH (1948) Calciferol in tuberculous peritonitis with disseminated tuberculosis. BMJ 1:394
10. Furtado GC, Olivares-Villagomez D, Curotto de Lafaille MA, Wensky AK, Latkowski JA, Lafaille JJ (2001) Regulatory T cells in spontaneous autoimmune encephalomyelitis. Immunol Rev 182:122-134 (Pubitemid 33070213)
11. Garland CF, Garland FC, Gorham ED (1991) Can colon cancer incidence and death rates be reduced with calcium and vitamin D? Am J Clin Nutr 54:193S-201S
12. Gregori S, Casorati M, Amuchastegui S, Smiroldo S, Davalli MA, Adorini L (2001) Regulatory T cells induced by 1a, 25-dihydrox yvitamin D3 and mycophenolate mofetil treatment mediate transplantation tolerance. J Immunol 167:1945-1953 (Pubitemid 32747499)
13. Griffin MD, Lutz W, Phan WA, Bachman LA, McKean DJ, Kumar R (2001) Dendritic cell modulation by 1a, 25 dihydroxyvitamin D3 and its analogs: a vitamin D receptor-dependent pathway that promotes a persistent state of immaturity in vitro and in vivo. Proc Natl Acad Sci U S A 98:6800-6805 (Pubitemid 32538297)
14. Gysemans C, van Etten E, Overbergh L, Giulietti A, Eelen A, Waer M, Verstuyf ABR, Mathieu C (2008) Unaltered diabetes presentation in NOD mice lacking the vitamin D receptor. Diabetes 57:269-275
15. Hamzaoui K, Ben Dhifallah I, Karray E, Sassi FH, Hamzaoui A (2010) Vitamin D modulates peripheral immunity in patients with Behçet's disease. Clin Exp Rheumatol 28(4 Suppl 60):s50-s57
16. Holick MF (2004) Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. Am J Clin Nutr 80(8 Suppl):1678s-1679s
17. Karlsson MR, Rugtveit J, Brand Zaeg P (2004) Allergen responsive CD4+CD25+ regulatory T cells in children who have outgrown cow's milk allergy. J Exp Med 199:1679-1688 (Pubitemid 38822001)
18. Lapatsanis D, Moulas A, Cholevas V, Soukakos P, Papadopoulou ZL, Challa A (2005) Vitamin D: a necessity for children and adolescents in Greece. Calcif Tissue Int 77:348-355 (Pubitemid 41830849)
19. Maloy KJ, Powrie F (2001) Regulatory T cells in the control of immune pathology. Nat Immunol 2:816-822
20. Manolagas SC, Hustmyer FG, Yu XP (1990) Immunomodulating properties of 1, 25-dihydroxyvitamin D3. Kidney Int 38:S9-S16
21. Mathieu C, Adorini L (2002) The coming of age 1, 25-dihydrox yvitamin D3 analogs as immunomodulator agents. Trends Mol Med 8:174-179 (Pubitemid 34297090)
22. Mathieu C, Waer M, Casteels K, Laureys J, Bouillon R (1995) Prevention of type 1 diabetes in NOD mice by non hypercalcemic doses of an new structural analog of 1, 25-dihydroxyvitamin D3, KH1060. Endocrinology 3:866-872
23. Najada AS, Habashneh MS, Khader M (2004) The frequency of nutritional rickets among hospitalized infants and its relation to respiratory diseases. J Trop Pediatr 50:364-368 (Pubitemid 40017231)
24. Nemere I, Farach-Carson MC (1998) Membrane receptors for steroid hormones: a case for specific cell surface binding sites for vitamin D metabolites and estrogens. Biochem Biophys Res Commun 248:442-449
25. Ng WF, Duggan PJ, Ponchel F, Matarese G, Lombardi G, Edwards AD, Isaacs JD, Lechler RI (2001) Human CD4+CD25+ cells: a naturally occuring population of regulatory T cells. Blood 98:2736-2744
26. Norman AW (1998) Receptors for 1a-25 (OH) 2D3: past, present and future. J Bone Res 13:1360-1369
27. Pozzilli P, Manfrini S, Crino A, Picardi A, Leomanni C, Cherubini V (2005) Vitamin D3 and type 1 diabetes. Horm Metab Res 37:680-683
28. Prietl B, Pilz S, Wolf M, Tomaschitz A, Obermayer-Pietsch B, Graninger W, Pieber TR (2010) Vitamin D supplementation and regulatory T cells in apparently healthy subjects: vitamin D treatment for autoimmune diseases? Isr Med Assoc J 12:136-139
29. Read S, Malmstrom V, Powrie F (2000) Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25 (+) CD4 (+) regulatory cells that control intestinal inflammation. J Exp Med 192:295-302 (Pubitemid 30470312)
30. Sachan A, Gupta R, Das V, Agarwal A, Awasthi PK, Bhatia V (2005) High prevalence of vitamin D deficiency among pregnant women and their newborns in northern India. Am J Clin Nutr 81:1060-1064 (Pubitemid 41724946)
31. Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M (1995) Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor a-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 155:1151-1164
32. Sakaguchi S, Sakaguchi N, Shimizu J, Yamazaki S, Sakihama T, Itoh M, Kuniyasu Y, Nomura T, Toda M, Takahashi T (2001) Immunologic tolerance maintained by CD25+CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol Rev 182:18-32 (Pubitemid 33070205)
33. Takahashi T, Tagami T, Yamazaki S, Uede T, Shimizu J, Sakaguchi N, Mak TW, Sakaguchi S (2000) Immunologic self-tolerance maintained by CD25 (+) CD4 (+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J Exp Med 192:303-310
34. Takeuchi A, Reddy GS, Kobayashi T, Okano T, Park J, Sharma S (1998) Nuclear factor of activated T cells (NFAT) as a molecular target for 1a, 25-dihydroxyvitamin D3-mediated effects. J Immunol 160:209-218 (Pubitemid 28116731)
35. Tang J, Li BQ, Ruan J, Zhang LJ (2008) Expression of Foxp3 in CD4CD25 (high) Treg cells of neonatal cord blood. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 24:365-367
36. Thornton AM, Shevach EM (2000) Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific. J Immunol 164:183-190 (Pubitemid 30012989)