Pterostilbene-Induced Tumor Cytotoxicity: A Lysosomal Membrane Permeabilization-Dependent Mechanism

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Mena, Salvador ^a   Rodríguez, María L ^b   Ponsoda, Xavier ^b   Estrela, José M ^a,b   Jäättela, Marja ^c   Ortega, Angel L ^a,b  

^a Green Molecular   (Spain)

^b UNIVERSITY OF VALENCIA   (Spain)

^c DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; HEAT SHOCK PROTEIN 70; PTEROSTILBENE; RESVERATROL; STILBENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHAGOSOME; BIOACCUMULATION; BREAST ADENOCARCINOMA; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CANCER RESISTANCE; CELL CYCLE ARREST; CELL PERMEABILIZATION; COLON ADENOCARCINOMA; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA SYNTHESIS INHIBITION; DRUG CYTOTOXICITY; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR SIGNALING; LUNG CARCINOMA; LYSOSOMAL MEMBRANE PERMEABILIZATION; MELANOMA CELL; PROTEIN EXPRESSION; UPREGULATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; AUTOPHAGY; CASPASES; CELL DEATH; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; HSP70 HEAT-SHOCK PROTEINS; HUMANS; INHIBITORY CONCENTRATION 50; L-LACTATE DEHYDROGENASE; LYSOSOMES; MICROSCOPY, CONFOCAL; NECROSIS; NEOPLASMS; PERMEABILITY; PHAGOSOMES; STILBENES;

EID: 84866015741     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0044524     Document Type: Article

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