Activation of NF-κB in Basolateral Amygdala Is Required for Memory Reconsolidation in Auditory Fear Conditioning

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Si, Jijian ^a,b,c   Yang, Jianli ^b   Xue, Lifen ^c   Yang, Chenhao ^a,b,c   Luo, Yixiao ^c   Shi, Haishui ^c   Lu, Lin ^c  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b SHANDONG MENTAL HEALTH CENTER   (China)

^c PEKING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BUTYRIC ACID; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DNA; HISTONE DEACETYLASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; SALAZOSULFAPYRIDINE; SN 50;

ANIMAL EXPERIMENT; ARTICLE; AUDITORY MEMORY; BASOLATERAL AMYGDALA; CONDITIONING; DNA BINDING; GENE EXPRESSION; HISTONE ACETYLATION; MOLECULAR MECHANICS; NONHUMAN; PROTEIN SYNTHESIS; RAT; STRESS;

ACOUSTIC STIMULATION; AMYGDALA; ANIMALS; CONDITIONING, CLASSICAL; DISEASE MODELS, ANIMAL; FEAR; HISTONES; I-KAPPA B KINASE; ISOBUTYRATES; MEMORY; NF-KAPPA B; RATS; RATS, SPRAGUE-DAWLEY; STRESS DISORDERS, POST-TRAUMATIC; SULFASALAZINE;

EID: 84866007519     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0043973     Document Type: Article

References (41)

1. Elzinga BM, Bremner JD, (2002) Are the neural substrates of memory the final common pathway in posttraumatic stress disorder (PTSD)? J Affect Disord 70: 1-17.
2. Rau V, DeCola JP, Fanselow MS, (2005) Stress-induced enhancement of fear learning: an animal model of posttraumatic stress disorder. Neurosci Biobehav Rev 29: 1207-1223.
3. Monfils MH, Cowansage KK, Klann E, LeDoux JE, (2009) Extinction-reconsolidation boundaries: key to persistent attenuation of fear memories. Science 324: 951-955.
4. Teng FY, Tang BL, (2010) NF-kappaB signaling in neurite growth and neuronal survival. Rev Neurosci 21: 299-313.
5. Nader K, Schafe GE, Le Doux JE, (2000) Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval. Nature 406: 722-726.
6. Debiec J, LeDoux JE, Nader K, (2002) Cellular and systems reconsolidation in the hippocampus. Neuron 36: 527-538.
7. Wang SH, de Oliveira Alvares L, Nader K, (2009) Cellular and systems mechanisms of memory strength as a constraint on auditory fear reconsolidation. Nat Neurosci 12: 905-912.
8. Duvarci S, Nader K, (2004) Characterization of fear memory reconsolidation. J Neurosci 24: 9269-9275.
9. Duvarci S, Nader K, LeDoux JE, (2005) Activation of extracellular signal-regulated kinase- mitogen-activated protein kinase cascade in the amygdala is required for memory reconsolidation of auditory fear conditioning. Eur J Neurosci 21: 283-289.
10. Boccia M, Freudenthal R, Blake M, de la Fuente V, Acosta G, et al. (2007) Activation of hippocampal nuclear factor-kappa B by retrieval is required for memory reconsolidation. J Neurosci 27: 13436-13445.
11. Freudenthal R, Boccia MM, Acosta GB, Blake MG, Merlo E, et al. (2005) NF-kappaB transcription factor is required for inhibitory avoidance long-term memory in mice. Eur J Neurosci 21: 2845-2852.
12. Yang J, Yu J, Jia X, Zhu W, Zhao L, et al. (2011) Inhibition of nuclear factor-kappaB impairs reconsolidation of morphine reward memory in rats. Behav Brain Res 216: 592-596.
13. Verma IM, Stevenson JK, Schwarz EM, Van Antwerp D, Miyamoto S, (1995) Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation. Genes Dev 9: 2723-2735.
14. Mercurio F, Zhu H, Murray BW, Shevchenko A, Bennett BL, et al. (1997) IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation. Science 278: 860-866.
15. Kaltschmidt B, Kaltschmidt C, (2009) NF-kappaB in the nervous system. Cold Spring Harb Perspect Biol 1: a001271.
16. Merlo E, Freudenthal R, Maldonado H, Romano A, (2005) Activation of the transcription factor NF-kappaB by retrieval is required for long-term memory reconsolidation. Learn Mem 12: 23-29.
17. Yeh SH, Lin CH, Lee CF, Gean PW, (2002) A requirement of nuclear factor-kappaB activation in fear-potentiated startle. J Biol Chem 277: 46720-46729.
18. Ahn HJ, Hernandez CM, Levenson JM, Lubin FD, Liou HC, et al. (2008) c-Rel, an NF-kappaB family transcription factor, is required for hippocampal long-term synaptic plasticity and memory formation. Learn Mem 15: 539-549.
19. Kaltschmidt B, Ndiaye D, Korte M, Pothion S, Arbibe L, et al. (2006) NF-kappaB regulates spatial memory formation and synaptic plasticity through protein kinase A/CREB signaling. Mol Cell Biol 26: 2936-2946.
20. Meffert MK, Chang JM, Wiltgen BJ, Fanselow MS, Baltimore D, (2003) NF-kappa B functions in synaptic signaling and behavior. Nat Neurosci 6: 1072-1078.
21. Lubin FD, Sweatt JD, (2007) The IkappaB kinase regulates chromatin structure during reconsolidation of conditioned fear memories. Neuron 55: 942-957.
22. Davis M, (1992) The role of the amygdala in fear and anxiety. Annu Rev Neurosci 15: 353-375.
23. Izumi T, Boku S, Shinmin W, Inoue T, Konno K, et al. (2011) Retrieval of conditioned fear activates the basolateral and intercalated nucleus of amygdala. J Neurosci Res 89: 773-790.
24. Kasahara M, Groenink L, Olivier B, Sarnyai Z, (2011) Corticotropin-releasing factor (CRF) over-expression down-regulates hippocampal dopamine receptor protein expression and CREB activation in mice. Neuro Endocrinol Lett 32: 193-198.
25. Yiu AP, Rashid AJ, Josselyn SA (2011) Increasing CREB Function in the CA1 Region of Dorsal Hippocampus Rescues the Spatial Memory Deficits in a Mouse Model of Alzheimer's Disease. Neuropsychopharmacology.
26. Sah P, Faber ES, Lopez de Armentia M, Power J, (2003) The amygdaloid complex: anatomy and physiology. Physiol Rev 83: 803-834.
27. Pitkanen A, Savander V, LeDoux JE, (1997) Organization of intra-amygdaloid circuitries in the rat: an emerging framework for understanding functions of the amygdala. Trends Neurosci 20: 517-523.
28. Weber CK, Liptay S, Wirth T, Adler G, Schmid RM, (2000) Suppression of NF-kappaB activity by sulfasalazine is mediated by direct inhibition of IkappaB kinases alpha and beta. Gastroenterology 119: 1209-1218.
29. Sah P, Westbrook RF, (2008) Behavioural neuroscience: The circuit of fear. Nature 454: 589-590.
30. Baratti CM, Boccia MM, Blake MG, (2009) Pharmacological effects and behavioral interventions on memory consolidation and reconsolidation. Braz J Med Biol Res 42: 148-154.
31. Yeh SH, Lin CH, Gean PW, (2004) Acetylation of nuclear factor-kappaB in rat amygdala improves long-term but not short-term retention of fear memory. Mol Pharmacol 65: 1286-1292.
32. Lubin FD, Ren Y, Xu X, Anderson AE, (2007) Nuclear factor-kappa B regulates seizure threshold and gene transcription following convulsant stimulation. J Neurochem 103: 1381-1395.
33. Ghosh S, Karin M, (2002) Missing pieces in the NF-kappaB puzzle. Cell 109Suppl: S81-96.
34. Bredy TW, Barad M, (2008) The histone deacetylase inhibitor valproic acid enhances acquisition, extinction, and reconsolidation of conditioned fear. Learn Mem 15: 39-45.
35. Alarcon JM, Malleret G, Touzani K, Vronskaya S, Ishii S, et al. (2004) Chromatin acetylation, memory, and LTP are impaired in CBP+/- mice: a model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration. Neuron 42: 947-959.
36. Wood MA, Attner MA, Oliveira AM, Brindle PK, Abel T, (2006) A transcription factor-binding domain of the coactivator CBP is essential for long-term memory and the expression of specific target genes. Learn Mem 13: 609-617.
37. Yamamoto Y, Verma UN, Prajapati S, Kwak YT, Gaynor RB, (2003) Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression. Nature 423: 655-659.
38. Viatour P, Legrand-Poels S, van Lint C, Warnier M, Merville MP, et al. (2003) Cytoplasmic IkappaBalpha increases NF-kappaB-independent transcription through binding to histone deacetylase (HDAC) 1 and HDAC3. J Biol Chem 278: 46541-46548.
39. Maddox SA, Schafe GE, (2011) Epigenetic alterations in the lateral amygdala are required for reconsolidation of a Pavlovian fear memory. Learn Mem 18: 579-593.
40. Li FQ, Xue YX, Wang JS, Fang Q, Li YQ, et al. (2010) Basolateral amygdala cdk5 activity mediates consolidation and reconsolidation of memories for cocaine cues. J Neurosci 30: 10351-10359.
41. Paxinos G, Watson C (2005) The rat brain in stereotaxic coordinates: Amsterdam: Elsevier Academic Press.