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Volumn 31, Issue 8, 2012, Pages 1231-1238

Serum leptin levels are associated with the presence of syndesmophytes in male patients with ankylosing spondylitis

Author keywords

Ankylosing spondylitis; Leptin; Syndesmophyte

Indexed keywords

ALKALINE PHOSPHATASE; BONE SPECIFIC ALKALINE PHOSPHATASE; COLLAGEN TYPE 1; LEPTIN; OSTEOCALCIN; TELOPEPTIDE; UNCLASSIFIED DRUG;

EID: 84866004136     PISSN: 07703198     EISSN: 14349949     Source Type: Journal    
DOI: 10.1007/s10067-012-1999-z     Document Type: Article
Times cited : (23)

References (45)
  • 1
    • 76649094260 scopus 로고    scopus 로고
    • Disease modification in ankylosing spondylitis
    • Maksymowych WP (2010) Disease modification in ankylosing spondylitis. Nat Rev Rheumatol 6(2):75-81
    • (2010) Nat Rev Rheumatol , vol.6 , Issue.2 , pp. 75-81
    • Maksymowych, W.P.1
  • 2
    • 3843108009 scopus 로고    scopus 로고
    • Osteoporosis and ankylosing spondylitis
    • El Maghraoui A (2004) Osteoporosis and ankylosing spondylitis. Joint Bone Spine 71(4):291-295
    • (2004) Joint Bone Spine , vol.71 , Issue.4 , pp. 291-295
    • El Maghraoui, A.1
  • 3
    • 0028198150 scopus 로고
    • Bone mineral density and vertebral compression fracture rates in ankylosing spondylitis
    • Donnelly S, Doyle DV, Denton A, Rolfe I, McCloskey EV et al (1994) Bone mineral density and vertebral compression fracture rates in ankylosing spondylitis. Ann Rheum Dis 53(2):117-121
    • (1994) Ann Rheum Dis , vol.53 , Issue.2 , pp. 117-121
    • Donnelly, S.1    Doyle, D.V.2    Denton, A.3    Rolfe, I.4    McCloskey, E.V.5
  • 4
    • 22244456027 scopus 로고    scopus 로고
    • Bone loss is detected more frequently in patients with ankylosing spondylitis with syndesmophytes
    • Karberg K, Zochling J, Sieper J, Felsenberg D, Braun J (2005) Bone loss is detected more frequently in patients with ankylosing spondylitis with syndesmophytes. J Rheumatol 32(7):1290-1298
    • (2005) J Rheumatol , vol.32 , Issue.7 , pp. 1290-1298
    • Karberg, K.1    Zochling, J.2    Sieper, J.3    Felsenberg, D.4    Braun, J.5
  • 5
    • 31544457103 scopus 로고    scopus 로고
    • Mechanisms of disease: Is osteoporosis the obesity of bone?
    • Rosen CJ, Bouxsein ML (2006) Mechanisms of disease: Is osteoporosis the obesity of bone? Nat Clin Pract Rheumatol 2(1):35-43
    • (2006) Nat Clin Pract Rheumatol , vol.2 , Issue.1 , pp. 35-43
    • Rosen, C.J.1    Bouxsein, M.L.2
  • 7
    • 58149498221 scopus 로고    scopus 로고
    • Dissociation of the neuronal regulation of bone mass and energy metabolism by leptin in vivo
    • Shi Y, Yadav VK, Suda N, Liu XS, Guo XE et al (2008) Dissociation of the neuronal regulation of bone mass and energy metabolism by leptin in vivo. Proc Natl Acad Sci USA 105(51):20529-20533
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.51 , pp. 20529-20533
    • Shi, Y.1    Yadav, V.K.2    Suda, N.3    Liu, X.S.4    Guo, X.E.5
  • 8
    • 77956621348 scopus 로고    scopus 로고
    • Leptin functions peripherally to regulate differentiation of mesenchymal progenitor cells
    • Scheller EL, Song J, Dishowitz MI, Soki FN, Hankenson KD et al (2010) Leptin functions peripherally to regulate differentiation of mesenchymal progenitor cells. Stem Cells 28(6):1071-1080
    • (2010) Stem Cells , vol.28 , Issue.6 , pp. 1071-1080
    • Scheller, E.L.1    Song, J.2    Dishowitz, M.I.3    Soki, F.N.4    Hankenson, K.D.5
  • 9
    • 0036234187 scopus 로고    scopus 로고
    • Leptin stimulates human osteobltic cell proliferation, de novo collagen syn thesis, and mineralization: Impact on differentiation markers, apoptosis, and osteocltic signaling
    • Gordeladze JO, Drevon CA, Syversen U, Reseland JE (2002) Leptin stimulates human osteobltic cell proliferation, de novo collagen synthesis, and mineralization: Impact on differentiation markers, apoptosis, and osteocltic signaling. J Cell Biochem 85 (4):825-836
    • (2002) J Cell Biochem , vol.85 , Issue.4 , pp. 825-836
    • Gordeladze, J.O.1    Drevon, C.A.2    Syversen, U.3    Reseland, J.E.4
  • 10
    • 0037174178 scopus 로고    scopus 로고
    • Role of leptin in bone growth: Central player or peripheral supporter?
    • Reseland JE, Gordeladze JO (2002) Role of leptin in bone growth: Central player or peripheral supporter? FEBS Lett 528(1-3):40-42
    • (2002) FEBS Lett , vol.528 , Issue.1-3 , pp. 40-42
    • Reseland, J.E.1    Gordeladze, J.O.2
  • 11
    • 0036708144 scopus 로고    scopus 로고
    • Is leptin the link between fat and bone mass?
    • Thomas T, Burguera B (2002) Is leptin the link between fat and bone mass? J Bone Miner Res 17(9):1563-1569
    • (2002) J Bone Miner Res , vol.17 , Issue.9 , pp. 1563-1569
    • Thomas, T.1    Burguera, B.2
  • 12
    • 0030936047 scopus 로고    scopus 로고
    • The metabolic significance of leptin in humans: Gender-bed differences in relationship to adiposity, insulin sensitivity, and energy expenditure
    • Kennedy A, Gettys TW, Watson P, Wallace P, Ganaway E et al (1997) The metabolic significance of leptin in humans: Gender-bed differences in relationship to adiposity, insulin sensitivity, and energy expenditure. J Clin Endocrinol Metab 82(4):1293-1300
    • (1997) J Clin Endocrinol Metab , vol.82 , Issue.4 , pp. 1293-1300
    • Kennedy, A.1    Gettys, T.W.2    Watson, P.3    Wallace, P.4    Ganaway, E.5
  • 13
    • 0021272107 scopus 로고
    • Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria
    • van der Linden S, Valkenburg HA, Cats A (1984) Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria. Arthritis Rheum 27(4):361-368
    • (1984) Arthritis Rheum , vol.27 , Issue.4 , pp. 361-368
    • Van Der Linden, S.1    Valkenburg, H.A.2    Cats, A.3
  • 14
    • 4043058048 scopus 로고    scopus 로고
    • What is the most appropriate radiologic scoring method for ankylosing spondylitis? A comparison of the available methods bed on the Outcome Meures in Rheumatology Clinical Trials filter
    • Wanders AJ, Landewe RB, Spoorenberg A, Dougados M, van der Linden S et al (2004) What is the most appropriate radiologic scoring method for ankylosing spondylitis? A comparison of the available methods bed on the Outcome Meures in Rheumatology Clinical Trials filter. Arthritis Rheum 50(8):2622-2632
    • (2004) Arthritis Rheum , vol.50 , Issue.8 , pp. 2622-2632
    • Wanders, A.J.1    Landewe, R.B.2    Spoorenberg, A.3    Dougados, M.4    Van Der Linden, S.5
  • 15
    • 0003911968 scopus 로고
    • Sessment of fracture risk and its application to screening for postmenopausal osteoporosis
    • World Health Organization, Report of WHO Study Group
    • World Health Organization (1994) sessment of fracture risk and its application to screening for postmenopausal osteoporosis. Report of WHO Study Group. World Health Organ Tech Rep Ser 843:1-129
    • (1994) World Health Organ Tech Rep Ser , vol.843 , pp. 1-129
  • 16
    • 33645746168 scopus 로고    scopus 로고
    • Induction of leptin resistance through direct interaction of C-reactive protein with leptin
    • Chen K, Li F, Li J, Cai H, Strom S et al (2006) Induction of leptin resistance through direct interaction of C-reactive protein with leptin. Nat Med 12(4):425-432
    • (2006) Nat Med , vol.12 , Issue.4 , pp. 425-432
    • Chen, K.1    Li, F.2    Li, J.3    Cai, H.4    Strom, S.5
  • 17
    • 34247648780 scopus 로고    scopus 로고
    • Serum leptin levels correlate with interleukin-6 levels and disee activity in patients with ankylosing spondylitis
    • Park MC, Lee SW, Choi ST, Park YB, Lee SK (2007) Serum leptin levels correlate with interleukin-6 levels and disee activity in patients with ankylosing spondylitis. Scand J Rheumatol 36 (2):101-106
    • (2007) Scand J Rheumatol , vol.36 , Issue.2 , pp. 101-106
    • Park, M.C.1    Lee, S.W.2    Choi, S.T.3    Park, Y.B.4    Lee, S.K.5
  • 18
    • 0031454125 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha contributes to obesity-related hyperleptinemia by regulating leptin release from adipocytes
    • Kirchgessner TG, Uysal KT,Wiesbrock SM,MarinoMW, Hotamisligil GS (1997) Tumor necrosis factor-alpha contributes to obesity-related hyperleptinemia by regulating leptin release from adipocytes. J Clin Invest 100(11):2777-2782
    • (1997) J Clin Invest , vol.100 , Issue.11 , pp. 2777-2782
    • Kirchgessner, T.G.1    Uysal, K.T.2    Wiesbrock S.M.Marino, M.W.3    Hotamisligil, G.S.4
  • 20
    • 13444302226 scopus 로고    scopus 로고
    • The association of syndesmophytes with vertebral bone mineral density in patients with ankylosing spondylitis
    • Gilgil E, Kacar C, Tuncer T, Butun B (2005) The association of syndesmophytes with vertebral bone mineral density in patients with ankylosing spondylitis. J Rheumatol 32(2):292-294
    • (2005) J Rheumatol , vol.32 , Issue.2 , pp. 292-294
    • Gilgil, E.1    Kacar, C.2    Tuncer, T.3    Butun, B.4
  • 21
    • 34548633198 scopus 로고    scopus 로고
    • Adipose tissue, serum adipokines, and ghrelin in patients with ankylosing spondylitis
    • Toussirot E, Streit G, Nguyen NU, Dumoulin G, Le Huede G et al (2007) Adipose tissue, serum adipokines, and ghrelin in patients with ankylosing spondylitis. Metabolism 56(10):1383-1389
    • (2007) Metabolism , vol.56 , Issue.10 , pp. 1383-1389
    • Toussirot, E.1    Streit, G.2    Nguyen, N.U.3    Dumoulin, G.4    Le Huede, G.5
  • 22
    • 61649116369 scopus 로고    scopus 로고
    • Pro-inflammatory effect of leptin on peripheral blood mononuclear cells of patients with ankylosing spondylitis
    • Park MC, Chung SJ, Park YB, Lee SK (2009) Pro-inflammatory effect of leptin on peripheral blood mononuclear cells of patients with ankylosing spondylitis. Joint Bone Spine 76(2):170-175
    • (2009) Joint Bone Spine , vol.76 , Issue.2 , pp. 170-175
    • Park, M.C.1    Chung, S.J.2    Park, Y.B.3    Lee, S.K.4
  • 23
    • 79958110293 scopus 로고    scopus 로고
    • Leptin and adiponectin levels in patients with ankylosing spondylitis. The effect of infliximab treatment
    • Derdemezis CS, Filippatos TD, Voulgari PV, Tselepis AD, Drosos AA et al (2010) Leptin and adiponectin levels in patients with ankylosing spondylitis. The effect of infliximab treatment. Clin Exp Rheumatol 28(6):880-883
    • (2010) Clin Exp Rheumatol , vol.28 , Issue.6 , pp. 880-883
    • Derdemezis, C.S.1    Filippatos, T.D.2    Voulgari, P.V.3    Tselepis, A.D.4    Drosos, A.A.5
  • 24
    • 77952292557 scopus 로고    scopus 로고
    • Higher leptin levels in Asian Indians than Creoles and Europids: A potential explanation for increased metabolic risk
    • Lilja M, Rolandsson O, Shaw JE, Pauvaday V, Cameron AJ et al (2010) Higher leptin levels in Asian Indians than Creoles and Europids: A potential explanation for increased metabolic risk. Int J Obes (Lond) 34(5):878-885
    • (2010) Int J Obes (Lond) , vol.34 , Issue.5 , pp. 878-885
    • Lilja, M.1    Rolandsson, O.2    Shaw, J.E.3    Pauvaday, V.4    Cameron, A.J.5
  • 25
    • 84857920282 scopus 로고    scopus 로고
    • Development of new syndesmophytes and bridges in ankylosing spondylitis and their predictors: A longitudinal study
    • van Tubergen A, Ramiro S, van der Heijde D, Dougados M, Mielants H et al (2011) Development of new syndesmophytes and bridges in ankylosing spondylitis and their predictors: A longitudinal study. Ann Rheum Dis 71:518-23
    • (2011) Ann Rheum Dis , vol.71 , pp. 518-23
    • Van Tubergen, A.1    Ramiro, S.2    Van Der Heijde, D.3    Dougados, M.4    Mielants, H.5
  • 26
    • 58249103888 scopus 로고    scopus 로고
    • Inflammatory lesions of the spine on magnetic resonance imaging predict the development of new syndesmophytes in ankylosing spondylitis: Evidence of a relationship between inflammation and new bone formation
    • Maksymowych WP, Chiowchanwisawakit P, Clare T, Pedersen SJ, Ostergaard M et al (2009) Inflammatory lesions of the spine on magnetic resonance imaging predict the development of new syndesmophytes in ankylosing spondylitis: Evidence of a relationship between inflammation and new bone formation. Arthritis Rheum 60(1):93-102
    • (2009) Arthritis Rheum , vol.60 , Issue.1 , pp. 93-102
    • Maksymowych, W.P.1    Chiowchanwisawakit, P.2    Clare, T.3    Pedersen, S.J.4    Ostergaard, M.5
  • 28
    • 0141737573 scopus 로고    scopus 로고
    • Leptin inhibits bone formation through a hypothalamic relay: A central control of bone ms
    • Ducy P, Amling M, Takeda S, Priemel M, Schilling AF et al (2000) Leptin inhibits bone formation through a hypothalamic relay: A central control of bone ms. Cell 100(2):197-207
    • (2000) Cell , vol.100 , Issue.2 , pp. 197-207
    • Ducy, P.1    Amling, M.2    Takeda, S.3    Priemel, M.4    Schilling, A.F.5
  • 30
    • 34347272275 scopus 로고    scopus 로고
    • Opposite effects of leptin on bone metabolism: A dosedependent balance related to energy intake and insulin-like growth factor-I pathway
    • Martin A, David V, Malaval L, Lafage-Proust MH, Vico L et al (2007) Opposite effects of leptin on bone metabolism: A dosedependent balance related to energy intake and insulin-like growth factor-I pathway. Endocrinology 148(7):3419-3425
    • (2007) Endocrinology , vol.148 , Issue.7 , pp. 3419-3425
    • Martin, A.1    David, V.2    Malaval, L.3    Lafage-Proust, M.H.4    Vico, L.5
  • 31
    • 0032982438 scopus 로고    scopus 로고
    • Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes
    • Thomas T, Gori F, Khosla S, Jensen MD, Burguera B et al (1999) Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes. Endocrinology 140(4):1630-1638
    • (1999) Endocrinology , vol.140 , Issue.4 , pp. 1630-1638
    • Thomas, T.1    Gori, F.2    Khosla, S.3    Jensen, M.D.4    Burguera, B.5
  • 32
    • 0034918777 scopus 로고    scopus 로고
    • Leptin is expressed in and secreted from primary cultures of human osteoblasts and promotes bone mineralization
    • Reseland JE, Syversen U, Bakke I, Qvigstad G, Eide LG et al (2001) Leptin is expressed in and secreted from primary cultures of human osteoblasts and promotes bone mineralization. J Bone Miner Res 16(8):1426-1433
    • (2001) J Bone Miner Res , vol.16 , Issue.8 , pp. 1426-1433
    • Reseland, J.E.1    Syversen, U.2    Bakke, I.3    Qvigstad, G.4    Eide, L.G.5
  • 33
    • 33846170837 scopus 로고    scopus 로고
    • Leptin and bone turnover in monochorionic twins complicated by twin-twin transfusion syndrome
    • Bajoria R, Sooranna SR, Chatterjee R (2007) Leptin and bone turnover in monochorionic twins complicated by twin-twin transfusion syndrome. Osteoporos Int 18(2):193-200
    • (2007) Osteoporos Int , vol.18 , Issue.2 , pp. 193-200
    • Bajoria, R.1    Sooranna, S.R.2    Chatterjee, R.3
  • 34
    • 0347362880 scopus 로고    scopus 로고
    • Leptin and bonemineral density: A cross-sectional study in obese and nonobese men
    • Morberg CM, Tetens I, Black E, Toubro S, Soerensen TI et al (2003) Leptin and bonemineral density: A cross-sectional study in obese and nonobese men. J Clin Endocrinol Metab 88(12):5795-5800
    • (2003) J Clin Endocrinol Metab , vol.88 , Issue.12 , pp. 5795-5800
    • Morberg, C.M.1    Tetens, I.2    Black, E.3    Toubro, S.4    Soerensen, T.I.5
  • 35
    • 0037341460 scopus 로고    scopus 로고
    • Serum leptin levels, bone mineral density and osteoblast alkaline phosphatase activity in elderly men and women
    • Scariano JK, Garry PJ, Montoya GD, Chandani AK, Wilson JM et al (2003) Serum leptin levels, bone mineral density and osteoblast alkaline phosphatase activity in elderly men and women. Mech Ageing Dev 124(3):281-286
    • (2003) Mech Ageing Dev , vol.124 , Issue.3 , pp. 281-286
    • Scariano, J.K.1    Garry, P.J.2    Montoya, G.D.3    Chandani, A.K.4    Wilson, J.M.5
  • 36
    • 84855199657 scopus 로고    scopus 로고
    • Association between serum leptin and bone metabolic markers, and the development of heterotopic ossification of the spinal ligament in female patients with ossification of the posterior longitudinal ligament
    • Ikeda Y, Nakajima A, Aiba A, Koda M, Okawa A et al (2011) Association between serum leptin and bone metabolic markers, and the development of heterotopic ossification of the spinal ligament in female patients with ossification of the posterior longitudinal ligament. Eur Spine J 20(9):1450-1458
    • (2011) Eur Spine J , vol.20 , Issue.9 , pp. 1450-1458
    • Ikeda, Y.1    Nakajima, A.2    Aiba, A.3    Koda, M.4    Okawa, A.5
  • 38
    • 79961100171 scopus 로고    scopus 로고
    • Focal fat lesions at vertebral corners on magnetic resonance imaging predict the development of new syndesmophytes in ankylosing spondylitis
    • Chiowchanwisawakit P, Lambert RG, Conner-Spady B, Maksymowych WP (2011) Focal fat lesions at vertebral corners on magnetic resonance imaging predict the development of new syndesmophytes in ankylosing spondylitis. Arthritis Rheum 63(8):2215-2225
    • (2011) Arthritis Rheum , vol.63 , Issue.8 , pp. 2215-2225
    • Chiowchanwisawakit, P.1    Lambert, R.G.2    Conner-Spady, B.3    Maksymowych, W.P.4
  • 39
    • 77951573995 scopus 로고    scopus 로고
    • The fatty Romanus lesion: A non-inflammatory spinal MRI lesion specific for axial spondyloarthropathy
    • Bennett AN, Rehman A, Hensor EM, Marzo-Ortega H, Emery P et al (2010) The fatty Romanus lesion: A non-inflammatory spinal MRI lesion specific for axial spondyloarthropathy. Ann Rheum Dis 69(5):891-894
    • (2010) Ann Rheum Dis , vol.69 , Issue.5 , pp. 891-894
    • Bennett, A.N.1    Rehman, A.2    Hensor, E.M.3    Marzo-Ortega, H.4    Emery, P.5
  • 40
    • 77955176027 scopus 로고    scopus 로고
    • Local leptin production in osterthritis subchondral osteoblasts may be responsible for their abnormal phenotypic expression
    • Mutabaruka MS, Aoulad Aissa M, Delalandre A, Lavigne M, Lajeunesse D (2010) Local leptin production in osterthritis subchondral osteoblasts may be responsible for their abnormal phenotypic expression. Arthritis Res Ther 12(1):R20
    • (2010) Arthritis Res Ther , vol.12 , Issue.1
    • Mutabaruka, M.S.1    Aoulad Aissa, M.2    Delalandre, A.3    Lavigne, M.4    Lajeunesse, D.5
  • 41
    • 15244354175 scopus 로고    scopus 로고
    • Cytokine-mediated xanthine oxidase upregulation in chronic obstructive pulmonary disease's airways
    • Komaki Y, Sugiura H, Koarai A, Tomaki M, Ogawa H et al (2005) Cytokine-mediated xanthine oxidase upregulation in chronic obstructive pulmonary disease's airways. Pulm armacol Ther 18 (4):297-302
    • (2005) Pulm armacol Ther , vol.18 , Issue.4 , pp. 297-302
    • Komaki, Y.1    Sugiura, H.2    Koarai, A.3    Tomaki, M.4    Ogawa, H.5
  • 42
    • 77950641223 scopus 로고    scopus 로고
    • Immunohistochemical analysis of osteoblasts in zygapophyseal joints of patients with ankylosing spondylitis reveal repair mechanisms similar to osteoarthritis
    • Appel H, Maier R, Loddenkemper C, Kayser R, Meier O et al (2010) Immunohistochemical analysis of osteoblasts in zygapophyseal joints of patients with ankylosing spondylitis reveal repair mechanisms similar to osteoarthritis. J Rheumatol 37 (4):823-828
    • (2010) J Rheumatol , vol.37 , Issue.4 , pp. 823-828
    • Appel, H.1    Maier, R.2    Loddenkemper, C.3    Kayser, R.4    Meier, O.5
  • 44
    • 0032967846 scopus 로고    scopus 로고
    • Cigarette smoking, alcohol use, and physical activity in relation to serum leptin levels in a multiethnic population: The Miami Community Health Study
    • Donahue RP, Zimmet P, Bean JA, Decourten M, DeCarlo Donahue RA et al (1999) Cigarette smoking, alcohol use, and physical activity in relation to serum leptin levels in a multiethnic population: The Miami Community Health Study. Ann Epidemiol 9 (2):108-113
    • (1999) Ann Epidemiol , vol.9 , Issue.2 , pp. 108-113
    • Donahue, R.P.1    Zimmet, P.2    Bean, J.A.3    Decourten, M.4    DeCarlo Donahue, R.A.5
  • 45
    • 74949143243 scopus 로고    scopus 로고
    • Narrative review: The role of leptin in human physiology: Emerging clinical applications
    • Kelesidis T, Kelesidis I, Chou S, Mantzoros CS (2010) Narrative review: The role of leptin in human physiology: Emerging clinical applications. Ann Intern Med 152(2):93-100
    • (2010) Ann Intern Med , vol.152 , Issue.2 , pp. 93-100
    • Kelesidis, T.1    Kelesidis, I.2    Chou, S.3    Mantzoros, C.S.4


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