PI3K-ERK1/2 activation contributes to extracellular H2O2 generation in amyloid β toxicity

Neuroscience Letters

Volumn 526, Issue 2, 2012, Pages

  Ha, Jong Seong ^a,b   Sung, Hye Yeong ^a,c   Lim, Heon M ^b   Kwon, Ki Sun ^a   Park, Sung Sup ^a,c  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Chungnam National University   (South Korea)

^c University of Science and Technology (UST)   (South Korea)

Author keywords

Amyloid peptide; ERK1 2; NADPH oxidase; Oxidative stress; PI3K

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SMALL INTERFERING RNA;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME ASSAY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; MOUSE; NERVE CELL CULTURE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RNA INTERFERENCE;

AMYLOID BETA-PEPTIDES; ANIMALS; CATALYTIC DOMAIN; CELLS, CULTURED; ENZYME ACTIVATION; EXTRACELLULAR SPACE; GENE KNOCKOUT TECHNIQUES; GLUTAMIC ACID; HYDROGEN PEROXIDE; MEMBRANE GLYCOPROTEINS; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NADPH OXIDASE; NEURONS; PEPTIDE FRAGMENTS; PHOSPHATIDYLINOSITOL 3-KINASES; PRIMARY CELL CULTURE; SUPEROXIDES;

EID: 84866002135     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2012.08.023     Document Type: Article

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