Pathophysiology of acute brain dysfunction: What's the cause of all this confusion?

Current Opinion in Critical Care

Volumn 18, Issue 5, 2012, Pages 518-526

  Hughes, Christopher G ^a   Patel, Mayur B ^a   Pandharipande, Pratik P ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Brain dysfunction; Delirium; Neuroinflammation; Sedation

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ACETYLCHOLINE; AMINO ACID; BENZODIAZEPINE DERIVATIVE; C REACTIVE PROTEIN; CHOLINERGIC RECEPTOR BLOCKING AGENT; DEXMEDETOMIDINE; DOPAMINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HYDROCORTISONE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LORAZEPAM; METHADONE; MIDAZOLAM; MORPHINE; NEUROTRANSMITTER; NORADRENALIN; PETHIDINE; PROCALCITONIN; PROPOFOL; REACTIVE OXYGEN METABOLITE; SEDATIVE AGENT; SEROTONIN; SOMATOMEDIN C; TUMOR NECROSIS FACTOR ALPHA; UNINDEXED DRUG;

ACUTE BRAIN DYSFUNCTION; APOPTOSIS; BLOOD BRAIN BARRIER; BRAIN ATROPHY; BRAIN BLOOD FLOW; BRAIN DYSFUNCTION; BRAIN PERFUSION; CLINICAL FEATURE; COMA; COMPUTER ASSISTED TOMOGRAPHY; CRITICAL ILLNESS; DELIRIUM; ELECTROENCEPHALOGRAPHY; ENDOTHELIAL DYSFUNCTION; HUMAN; INFLAMMATION; INTENSIVE CARE UNIT; MICROGLIA; NEUROCHEMISTRY; NEUROIMAGING; PATHOPHYSIOLOGY; REGULATORY MECHANISM; REVIEW; RISK FACTOR; SYNAPSE; WHITE MATTER;

APOPTOSIS; BENZODIAZEPINES; BLOOD-BRAIN BARRIER; BRAIN; BRAIN DISEASES; COMA; CONFUSION; CRITICAL ILLNESS; DELIRIUM; ELECTROENCEPHALOGRAPHY; HUMANS; INFLAMMATION; NEUROIMAGING; NEUROIMMUNOMODULATION; RISK FACTORS;

EID: 84866001464     PISSN: 10705295     EISSN: 15317072     Source Type: Journal    
DOI: 10.1097/MCC.0b013e328357effa     Document Type: Review

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