-
1
-
-
37149040245
-
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial
-
Pandharipande P.P., Pun B.T., Herr D.L., et al. Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial. JAMA 2007, 298:2644-2653.
-
(2007)
JAMA
, vol.298
, pp. 2644-2653
-
-
Pandharipande, P.P.1
Pun, B.T.2
Herr, D.L.3
-
2
-
-
67649210721
-
Delirium in elderly adults: diagnosis, prevention and treatment
-
Fong T.G., Tulebaev S.R., Inouye S.K. Delirium in elderly adults: diagnosis, prevention and treatment. Nat Rev Neurol 2009, 5:210-220.
-
(2009)
Nat Rev Neurol
, vol.5
, pp. 210-220
-
-
Fong, T.G.1
Tulebaev, S.R.2
Inouye, S.K.3
-
3
-
-
0035814368
-
Delirium in mechanically ventilated patients: validity and reliability of the confusion assessment method for the intensive care unit (CAM-ICU)
-
Ely E.W., Inouye S.K., Bernard G.R., et al. Delirium in mechanically ventilated patients: validity and reliability of the confusion assessment method for the intensive care unit (CAM-ICU). JAMA 2001, 286:2703-2710.
-
(2001)
JAMA
, vol.286
, pp. 2703-2710
-
-
Ely, E.W.1
Inouye, S.K.2
Bernard, G.R.3
-
4
-
-
12944335010
-
An information integration theory of consciousness
-
Tononi G. An information integration theory of consciousness. BMC Neurosci 2004, 5:42.
-
(2004)
BMC Neurosci
, vol.5
, pp. 42
-
-
Tononi, G.1
-
5
-
-
25844463573
-
Breakdown of cortical effective connectivity during sleep
-
Massimini M., Ferrarelli F., Huber R., Esser S.K., Singh H., Tononi G. Breakdown of cortical effective connectivity during sleep. Science 2005, 309:2228-2232.
-
(2005)
Science
, vol.309
, pp. 2228-2232
-
-
Massimini, M.1
Ferrarelli, F.2
Huber, R.3
Esser, S.K.4
Singh, H.5
Tononi, G.6
-
6
-
-
77249083662
-
Breakdown in cortical effective connectivity during midazolam-induced loss of consciousness
-
Ferrarelli F., Massimini M., Sarasso S., et al. Breakdown in cortical effective connectivity during midazolam-induced loss of consciousness. Proc Nat Acad Sci USA 2010, 107:2681-2686.
-
(2010)
Proc Nat Acad Sci USA
, vol.107
, pp. 2681-2686
-
-
Ferrarelli, F.1
Massimini, M.2
Sarasso, S.3
-
7
-
-
70049094398
-
Qualia: the geometry of integrated information
-
Balduzzi D., Tononi G. Qualia: the geometry of integrated information. PLoS Comput Biol 2009, 5:e1000462.
-
(2009)
PLoS Comput Biol
, vol.5
-
-
Balduzzi, D.1
Tononi, G.2
-
8
-
-
35548966684
-
Loss of IQ in the ICU brain injury without the insult
-
Gunther M.L., Jackson J.C., Ely E.W. Loss of IQ in the ICU brain injury without the insult. Med Hypotheses 2007, 69:1179-1182.
-
(2007)
Med Hypotheses
, vol.69
, pp. 1179-1182
-
-
Gunther, M.L.1
Jackson, J.C.2
Ely, E.W.3
-
9
-
-
70350279036
-
Breakdown of effective connectivity during slow wave sleep: investigating the mechanism underlying a cortical gate using large-scale modeling
-
Esser S.K., Hill S., Tononi G. Breakdown of effective connectivity during slow wave sleep: investigating the mechanism underlying a cortical gate using large-scale modeling. J Neurophysiol 2009, 102:2096-2111.
-
(2009)
J Neurophysiol
, vol.102
, pp. 2096-2111
-
-
Esser, S.K.1
Hill, S.2
Tononi, G.3
-
10
-
-
33644851831
-
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients
-
Pandharipande P., Shintani A., Peterson J., et al. Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients. Anesthesiology 2006, 104:21-26.
-
(2006)
Anesthesiology
, vol.104
, pp. 21-26
-
-
Pandharipande, P.1
Shintani, A.2
Peterson, J.3
-
11
-
-
27644457084
-
Hypothalamic regulation of sleep and circadian rhythms
-
Saper C.B., Scammell T.E., Lu J. Hypothalamic regulation of sleep and circadian rhythms. Nature 2005, 437:1257-1263.
-
(2005)
Nature
, vol.437
, pp. 1257-1263
-
-
Saper, C.B.1
Scammell, T.E.2
Lu, J.3
-
12
-
-
76949086562
-
Age- and gender-specific changes of hypocretin immunopositive neurons in C57Bl/6 mice
-
Brownell S.E., Conti B. Age- and gender-specific changes of hypocretin immunopositive neurons in C57Bl/6 mice. Neurosci Lett 2010, 472:29-32.
-
(2010)
Neurosci Lett
, vol.472
, pp. 29-32
-
-
Brownell, S.E.1
Conti, B.2
-
13
-
-
60849097577
-
The involvement of hypothalamic sleep pathways in general anesthesia: testing the hypothesis using the GABAA receptor beta3N265M knock-in mouse
-
Zecharia A.Y., Nelson L.E., Gent T.C., et al. The involvement of hypothalamic sleep pathways in general anesthesia: testing the hypothesis using the GABAA receptor beta3N265M knock-in mouse. J Neurosci 2009, 29:2177-2187.
-
(2009)
J Neurosci
, vol.29
, pp. 2177-2187
-
-
Zecharia, A.Y.1
Nelson, L.E.2
Gent, T.C.3
-
14
-
-
70349108442
-
Lipopolysaccharide challenge-induced suppression of Fos in hypothalamic orexin neurons: their potential role in sickness behavior
-
Gaykema R.P., Goehler L.E. Lipopolysaccharide challenge-induced suppression of Fos in hypothalamic orexin neurons: their potential role in sickness behavior. Brain Behav Immun 2009, 23:926-930.
-
(2009)
Brain Behav Immun
, vol.23
, pp. 926-930
-
-
Gaykema, R.P.1
Goehler, L.E.2
-
15
-
-
65549143818
-
Consequences of sleep deprivation on neurotransmitter receptor expression and function
-
Longordo F., Kopp C., Luthi A. Consequences of sleep deprivation on neurotransmitter receptor expression and function. Eur J Neurosci 2009, 29:1810-1819.
-
(2009)
Eur J Neurosci
, vol.29
, pp. 1810-1819
-
-
Longordo, F.1
Kopp, C.2
Luthi, A.3
-
16
-
-
24944571671
-
Vivid dreams, hallucinations, psychosis and REM sleep in Guillain-Barre syndrome
-
Cochen V., Arnulf I., Demeret S., et al. Vivid dreams, hallucinations, psychosis and REM sleep in Guillain-Barre syndrome. Brain 2005, 128:2535-2545.
-
(2005)
Brain
, vol.128
, pp. 2535-2545
-
-
Cochen, V.1
Arnulf, I.2
Demeret, S.3
-
17
-
-
79951725860
-
Contribution of sedative-hypnotic agents to delirium via modulation of the sleep pathway
-
Sanders R.D., Maze M. Contribution of sedative-hypnotic agents to delirium via modulation of the sleep pathway. Can J Anaesth 2011, 58:149-156.
-
(2011)
Can J Anaesth
, vol.58
, pp. 149-156
-
-
Sanders, R.D.1
Maze, M.2
-
18
-
-
36549068174
-
Disruption of large-scale brain systems in advanced aging
-
Andrews-Hanna J.R., Snyder A.Z., Vincent J.L., et al. Disruption of large-scale brain systems in advanced aging. Neuron 2007, 56:924-935.
-
(2007)
Neuron
, vol.56
, pp. 924-935
-
-
Andrews-Hanna, J.R.1
Snyder, A.Z.2
Vincent, J.L.3
-
19
-
-
67650624499
-
Disturbed beta band functional connectivity in patients with mild cognitive impairment: an MEG study
-
Gomez C., Stam C.J., Hornero R., Fernandez A., Maestu F. Disturbed beta band functional connectivity in patients with mild cognitive impairment: an MEG study. IEEE Trans Biomed Eng 2009, 56:1683-1690.
-
(2009)
IEEE Trans Biomed Eng
, vol.56
, pp. 1683-1690
-
-
Gomez, C.1
Stam, C.J.2
Hornero, R.3
Fernandez, A.4
Maestu, F.5
-
20
-
-
18144363240
-
Activity and connectivity of brain mood regulating circuit in depression: a functional magnetic resonance study
-
Anand A., Li Y., Wang Y., et al. Activity and connectivity of brain mood regulating circuit in depression: a functional magnetic resonance study. Biol Psychiatry 2005, 57:1079-1088.
-
(2005)
Biol Psychiatry
, vol.57
, pp. 1079-1088
-
-
Anand, A.1
Li, Y.2
Wang, Y.3
-
21
-
-
58949094701
-
Graph theoretical analysis of magnetoencephalographic functional connectivity in Alzheimer's disease
-
Stam C.J., de Haan W., Daffertshofer A., et al. Graph theoretical analysis of magnetoencephalographic functional connectivity in Alzheimer's disease. Brain 2009, 132:213-224.
-
(2009)
Brain
, vol.132
, pp. 213-224
-
-
Stam, C.J.1
de Haan, W.2
Daffertshofer, A.3
-
22
-
-
60549103853
-
Complex brain networks: graph theoretical analysis of structural and functional systems
-
Bullmore E., Sporns O. Complex brain networks: graph theoretical analysis of structural and functional systems. Nat Rev Neurosci 2009, 10:186-198.
-
(2009)
Nat Rev Neurosci
, vol.10
, pp. 186-198
-
-
Bullmore, E.1
Sporns, O.2
-
23
-
-
79953126108
-
Brain autopsy findings in intensive care unit patients previously suffering from delirium: A pilot study
-
Janz D.R., Abel T.W., Jackson J.C., Gunther M., Heckers S., Ely E.W. Brain autopsy findings in intensive care unit patients previously suffering from delirium: A pilot study. J Crit Care 2010.
-
(2010)
J Crit Care
-
-
Janz, D.R.1
Abel, T.W.2
Jackson, J.C.3
Gunther, M.4
Heckers, S.5
Ely, E.W.6
-
24
-
-
54149092555
-
Evolution of the aging brain transcriptome, synaptic regulation
-
Loerch P.M., Lu T., Dakin K.A. Evolution of the aging brain transcriptome, synaptic regulation. PLoS One 2008, 3:e3329.
-
(2008)
PLoS One
, vol.3
-
-
Loerch, P.M.1
Lu, T.2
Dakin, K.A.3
-
25
-
-
77950229880
-
Neural mechanisms of ageing and cognitive decline
-
Bishop N.A., Lu T., Yankner B.A. Neural mechanisms of ageing and cognitive decline. Nature 2010, 464:529-535.
-
(2010)
Nature
, vol.464
, pp. 529-535
-
-
Bishop, N.A.1
Lu, T.2
Yankner, B.A.3
-
26
-
-
33744962100
-
Interleukin-1beta enhances GABAA receptor cell-surface expression by a phosphatidylinositol 3-kinase/Akt pathway: relevance to sepsis-associated encephalopathy
-
Serantes R., Arnalich F., Figueroa M., et al. Interleukin-1beta enhances GABAA receptor cell-surface expression by a phosphatidylinositol 3-kinase/Akt pathway: relevance to sepsis-associated encephalopathy. J Biol Chem 2006, 281:14632-14643.
-
(2006)
J Biol Chem
, vol.281
, pp. 14632-14643
-
-
Serantes, R.1
Arnalich, F.2
Figueroa, M.3
-
27
-
-
34447116242
-
A GABAergic system in airway epithelium is essential for mucus overproduction in asthma
-
Xiang Y.Y., Wang S., Liu M., et al. A GABAergic system in airway epithelium is essential for mucus overproduction in asthma. Nat Med 2007, 13:862-867.
-
(2007)
Nat Med
, vol.13
, pp. 862-867
-
-
Xiang, Y.Y.1
Wang, S.2
Liu, M.3
-
28
-
-
62949136820
-
Hyperammonemia increases GABAergic tone in the cerebellum but decreases it in the rat cortex
-
Cauli O., Mansouri M.T., Agusti A., Felipo V. Hyperammonemia increases GABAergic tone in the cerebellum but decreases it in the rat cortex. Gastroenterology 2009, 136(1359-67):e1-e2.
-
(2009)
Gastroenterology
, vol.136
, Issue.67-1359
-
-
Cauli, O.1
Mansouri, M.T.2
Agusti, A.3
Felipo, V.4
-
29
-
-
77955488524
-
Hyperammonemia induces neuroinflammation that contributes to cognitive impairment in rats with hepatic encephalopathy
-
Rodrigo R., Cauli O., Gomez-Pinedo U., et al. Hyperammonemia induces neuroinflammation that contributes to cognitive impairment in rats with hepatic encephalopathy. Gastroenterology 2010.
-
(2010)
Gastroenterology
-
-
Rodrigo, R.1
Cauli, O.2
Gomez-Pinedo, U.3
-
30
-
-
0027335709
-
Ammonia potentiates GABAA response in dissociated rat cortical neurons
-
Takahashi K., Kameda H., Kataoka M., Sanjou K., Harata N., Akaike N. Ammonia potentiates GABAA response in dissociated rat cortical neurons. Neurosci Lett 1993, 151:51-54.
-
(1993)
Neurosci Lett
, vol.151
, pp. 51-54
-
-
Takahashi, K.1
Kameda, H.2
Kataoka, M.3
Sanjou, K.4
Harata, N.5
Akaike, N.6
-
31
-
-
78650357668
-
Comparison of sedation with dexmedetomidine versus lorazepam in septic ICU patients
-
Pandharipande P., Girard T.D., Sanders R.D., Maze M., Ely E.W. Comparison of sedation with dexmedetomidine versus lorazepam in septic ICU patients. Crit Care 2008, 12:P275.
-
(2008)
Crit Care
, vol.12
-
-
Pandharipande, P.1
Girard, T.D.2
Sanders, R.D.3
Maze, M.4
Ely, E.W.5
-
32
-
-
59649126760
-
Benzodiazepine and opioid use and the duration of intensive care unit delirium in an older population
-
Pisani M.A., Murphy T.E., Araujo K.L., Slattum P., Van Ness P.H., Inouye S.K. Benzodiazepine and opioid use and the duration of intensive care unit delirium in an older population. Crit Care Med 2009, 37:177-183.
-
(2009)
Crit Care Med
, vol.37
, pp. 177-183
-
-
Pisani, M.A.1
Murphy, T.E.2
Araujo, K.L.3
Slattum, P.4
Van Ness, P.H.5
Inouye, S.K.6
-
33
-
-
34247569324
-
Delirium in older people
-
Young J., Inouye S.K. Delirium in older people. BMJ 2007, 334:842-846.
-
(2007)
BMJ
, vol.334
, pp. 842-846
-
-
Young, J.1
Inouye, S.K.2
-
34
-
-
34547758470
-
Muscarinic M2 and M1 receptors reduce GABA release by Ca2+ channel modulation through activation of PI3K/Ca2+ -independent and PLC/Ca2+ -dependent PKC
-
Salgado H., Bellay T., Nichols J.A., Bose M., Martinolich L., Perrotti L., et al. Muscarinic M2 and M1 receptors reduce GABA release by Ca2+ channel modulation through activation of PI3K/Ca2+ -independent and PLC/Ca2+ -dependent PKC. Journal of neurophysiology 2007, 98:952-965.
-
(2007)
Journal of neurophysiology
, vol.98
, pp. 952-965
-
-
Salgado, H.1
Bellay, T.2
Nichols, J.A.3
Bose, M.4
Martinolich, L.5
Perrotti, L.6
-
35
-
-
51449106500
-
Cholinergic deficiency hypothesis in delirium: a synthesis of current evidence
-
Hshieh T.T., Fong T.G., Marcantonio E.R., Inouye S.K. Cholinergic deficiency hypothesis in delirium: a synthesis of current evidence. J Gerontol A Biol Sci Med Sci 2008, 63:764-772.
-
(2008)
J Gerontol A Biol Sci Med Sci
, vol.63
, pp. 764-772
-
-
Hshieh, T.T.1
Fong, T.G.2
Marcantonio, E.R.3
Inouye, S.K.4
-
36
-
-
58149094160
-
The Neurology of consciousness: an overview
-
Academic Press, London, S. Laureys, G. Tononi (Eds.)
-
Tononi G., Laureys S. The Neurology of consciousness: an overview. The neurology of consciousness 2009, 375-412. Academic Press, London. 1st ed. S. Laureys, G. Tononi (Eds.).
-
(2009)
The neurology of consciousness
, pp. 375-412
-
-
Tononi, G.1
Laureys, S.2
-
37
-
-
14544267665
-
The neuroscience of mammalian associative learning
-
Fanselow M.S., Poulos A.M. The neuroscience of mammalian associative learning. Annu Rev Psychol 2005, 56:207-234.
-
(2005)
Annu Rev Psychol
, vol.56
, pp. 207-234
-
-
Fanselow, M.S.1
Poulos, A.M.2
|