-
1
-
-
84855831273
-
Aldo-keto reductases pro-tect lung adenocarcinoma cells from the acute toxicity of B[a]P-7 8-trans-dihydrodiol
-
Abedin, Z., Sen, S., and Field, J. (2012). Aldo-keto reductases pro-tect lung adenocarcinoma cells from the acute toxicity of B[a]P-7,8-trans-dihydrodiol. Chem. Res. Toxicol. 25, 113-121.
-
(2012)
Chem. Res. Toxicol.
, vol.25
, pp. 113-121
-
-
Abedin, Z.1
Sen, S.2
Field, J.3
-
2
-
-
80053305353
-
Aldo-keto reductase-7A protects liver cells and tissues from acetaminophen-induced oxidative stress and hepato-toxicity
-
Ahmed, M. M., Wang, T., Luo, Y., Ye, S., Wu, Q., Guo, Z., Roebuck, B. D., Sut-ter, T. R., andYang, J.Y. (2011). Aldo-keto reductase-7A protects liver cells and tissues from acetaminophen-induced oxidative stress and hepato-toxicity. Hepatology 54, 1322-1332.
-
(2011)
Hepatology
, vol.54
, pp. 1322-1332
-
-
Ahmed, M.M.1
Wang, T.2
Luo, Y.3
Ye, S.4
Wu, Q.5
Guo, Z.6
Roebuck, B.D.7
Sut-ter, T.R.8
Yang, J.Y.9
-
3
-
-
0345550290
-
Regu-lation of aldehyde reductase expres-sion by STAF and CHOP
-
Barski, O. A., Papusha, V. Z., Kunkel, G. R., and Gabbay, K. H. (2004). Regu-lation of aldehyde reductase expres-sion by STAF and CHOP. Genomics 83, 119-129.
-
(2004)
Genomics
, vol.83
, pp. 119-129
-
-
Barski, O.A.1
Papusha, V.Z.2
Kunkel, G.R.3
Gabbay, K.H.4
-
4
-
-
54549110136
-
The aldo-keto reductase superfamily and its role in drug metabolism and detox-ification
-
Barski, O. A., Tipparaju, S. M., and Bhatnagar, A. (2008). The aldo-keto reductase superfamily and its role in drug metabolism and detox-ification. Drug Metab. Rev. 40, 553-624.
-
(2008)
Drug Metab. Rev.
, vol.40
, pp. 553-624
-
-
Barski, O.A.1
Tipparaju, S.M.2
Bhatnagar, A.3
-
5
-
-
60449106323
-
The aldo-keto reductase AKR1C3 contributes to 7,12-dimethylbenz(a)anthracene-3 4-dihydrodiol mediated oxidative DNA damage in myeloid cells: implications for leukemogenesis
-
Birtwistle, J., Hayden, R. E., Khanim, F. L., Green, R. M., Pearce, C., Davies, N. J., Wake, N., Schrewe, H., Ride, J. P., Chipman, J. K., and Bunce, C. M. (2009). The aldo-keto reductase AKR1C3 contributes to 7,12-dimethylbenz(a)anthracene-3,4-dihydrodiol mediated oxidative DNA damage in myeloid cells: implications for leukemogenesis. Mutat. Res. 662, 67-74.
-
(2009)
Mutat. Res.
, vol.662
, pp. 67-74
-
-
Birtwistle, J.1
Hayden, R.E.2
Khanim, F.L.3
Green, R.M.4
Pearce, C.5
Davies, N.J.6
Wake, N.7
Schrewe, H.8
Ride, J.P.9
Chipman, J.K.10
Bunce, C.M.11
-
6
-
-
0033083205
-
Isoform-specific induction of a human aldo-keto reductase by polycyclic aro-matic hydrocarbons (PAHs), elec-trophiles,and oxidative stress: impli-cations for the alternative pathway of PAH activation catalyzed by human dihydrodiol dehydrogenase
-
Burczynski, M. E., Lin, H. K., and Penning, T. M. (1999). Isoform-specific induction of a human aldo-keto reductase by polycyclic aro-matic hydrocarbons (PAHs), elec-trophiles,and oxidative stress: impli-cations for the alternative pathway of PAH activation catalyzed by human dihydrodiol dehydrogenase. Cancer Res. 59, 607-614.
-
(1999)
Cancer Res
, vol.59
, pp. 607-614
-
-
Burczynski, M.E.1
Lin, H.K.2
Penning, T.M.3
-
7
-
-
79952453380
-
Association of intronic variants of the KCNAB1 gene with lateral temporal epilepsy
-
Busolin, G., Malacrida, S., Bisulli, F., Striano, P., Di Bonaventura, C., Egeo, G., Pasini, E., Cianci, V., Ferlazzo, E., Bianchi, A., Coppola, G., Elia, M., Mecarelli, O., Gobbi, G., Casellato, S., Marchini, M., Binelli, S., Freri, E., Granata, T., Posar, A., Parmeggiani, A., Vigliano, P., Boniver, C., Aguglia, U., Striano, S., Tinuper, P., Giallonardo, A. T., Michelucci, R., and Nobile, C. (2011). Association of intronic variants of the KCNAB1 gene with lateral temporal epilepsy. Epilepsy Res. 94, 110-116.
-
(2011)
Epilepsy Res
, vol.94
, pp. 110-116
-
-
Busolin, G.1
Malacrida, S.2
Bisulli, F.3
Striano, P.4
Di Bonaventura, C.5
Egeo, G.6
Pasini, E.7
Cianci, V.8
Ferlazzo, E.9
Bianchi, A.10
Coppola, G.11
Elia, M.12
Mecarelli, O.13
Gobbi, G.14
Casellato, S.15
Marchini, M.16
Binelli, S.17
Freri, E.18
Granata, T.19
Posar, A.20
Parmeggiani, A.21
Vigliano, P.22
Boniver, C.23
Aguglia, U.24
Striano, S.25
Tinuper, P.26
Giallonardo, A.T.27
Michelucci, R.28
Nobile, C.29
more..
-
8
-
-
0035951661
-
Genomic organization of a human 5beta-reductase and its pseudogene and substrate selec-tivity of the expressed enzyme
-
Charbonneau, A., and The, V. L. (2001). Genomic organization of a human 5beta-reductase and its pseudogene and substrate selec-tivity of the expressed enzyme. Biochim. Biophys. Acta 1517, 228-235.
-
(2001)
Biochim. Biophys. Acta
, vol.1517
, pp. 228-235
-
-
Charbonneau, A.1
The, V.L.2
-
9
-
-
15544379141
-
Overexpres-sion of dihydrodiol dehydrogenase is associated with cisplatin-based chemotherapy resistance in ovarian cancer patients
-
Chen, Y. J., Yuan, C. C., Chow, K. C., Wang, P. H., Lai, C. R., Yen, M. S., and Wang, L. S. (2005). Overexpres-sion of dihydrodiol dehydrogenase is associated with cisplatin-based chemotherapy resistance in ovarian cancer patients. Gynecol. Oncol. 97, 110-117.
-
(2005)
Gynecol. Oncol.
, vol.97
, pp. 110-117
-
-
Chen, Y.J.1
Yuan, C.C.2
Chow, K.C.3
Wang, P.H.4
Lai, C.R.5
Yen, M.S.6
Wang, L.S.7
-
10
-
-
68049117221
-
Interleukin-6 regulates androgen synthesis in prostate cancer cells
-
Chun, J. Y., Nadiminty, N., Dutt, S., Lou, W., Yang, J. C., Kung, H. J., Evans, C. P., and Gao, A. C. (2009). Interleukin-6 regulates androgen synthesis in prostate cancer cells. Clin. Cancer Res. 15, 4815-4822.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 4815-4822
-
-
Chun, J.Y.1
Nadiminty, N.2
Dutt, S.3
Lou, W.4
Yang, J.C.5
Kung, H.J.6
Evans, C.P.7
Gao, A.C.8
-
11
-
-
79959786449
-
Disorders of bile acid synthesis
-
Clayton, P. T. (2011). Disorders of bile acid synthesis. J. Inherit. Metab. Dis. 34, 593-604.
-
(2011)
J. Inherit. Metab. Dis.
, vol.34
, pp. 593-604
-
-
Clayton, P.T.1
-
12
-
-
4644249735
-
Ubiquitous induction of resis-tance to platinum drugs in human ovarian, cervical, germ-cell and lung carcinoma tumor cells over-expressing isoforms 1 and 2 of dihydrodiol dehydrogenase
-
Deng, H. B., Adikari, M., Parekh, H. K., and Simpkins, H. (2004). Ubiquitous induction of resis-tance to platinum drugs in human ovarian, cervical, germ-cell and lung carcinoma tumor cells over-expressing isoforms 1 and 2 of dihydrodiol dehydrogenase. Can-cer Chemother. Pharmacol. 54, 301-307.
-
(2004)
Can-cer Chemother. Pharmacol.
, vol.54
, pp. 301-307
-
-
Deng, H.B.1
Adikari, M.2
Parekh, H.K.3
Simpkins, H.4
-
13
-
-
0037177887
-
Increased expression of dihydrodiol dehydro-genase induces resistance to cisplatin in human ovarian carcinoma cells
-
Deng, H. B., Parekh, H. K., Chow, K. C., and Simpkins, H. (2002). Increased expression of dihydrodiol dehydro-genase induces resistance to cisplatin in human ovarian carcinoma cells. J. Biol. Chem. 277, 15035-15043.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 15035-15043
-
-
Deng, H.B.1
Parekh, H.K.2
Chow, K.C.3
Simpkins, H.4
-
14
-
-
79958856252
-
Identification of aldo-keto reduc-tase AKR1B10 as a selective target for modification and inhibition by prostaglandin A(1): implications for antitumoral activity
-
Diez-Dacal, B., Gayarre, J., Gharbi, S., Timms, J. F., Coderch, C., Gago, F., and Perez-Sala, D. (2011). Identification of aldo-keto reduc-tase AKR1B10 as a selective target for modification and inhibition by prostaglandin A(1): implications for antitumoral activity. Cancer Res. 71, 4161-4171.
-
(2011)
Cancer Res
, vol.71
, pp. 4161-4171
-
-
Diez-Dacal, B.1
Gayarre, J.2
Gharbi, S.3
Timms, J.F.4
Coderch, C.5
Gago, F.6
Perez-Sala, D.7
-
15
-
-
79957569340
-
Protea-some inhibitors MG-132 and borte-zomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29
-
Ebert, B., Kisiela, M., Wsol, V., and Maser, E. (2011). Protea-some inhibitors MG-132 and borte-zomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29. Chem. Biol. Interact. 191, 239-249.
-
(2011)
Chem. Biol. Interact.
, vol.191
, pp. 239-249
-
-
Ebert, B.1
Kisiela, M.2
Wsol, V.3
Maser, E.4
-
16
-
-
33751087216
-
Bone mor-phogenetic protein-2 upregulates expression and function of voltage-gated K+ channels in human pul-monary artery smooth muscle cells
-
Fantozzi, I., Platoshyn, O., Wong, A. H., Zhang, S., Remillard, C. V., Fur-tado, M. R., Petrauskene, O. V., and Yuan, J. X. (2006). Bone mor-phogenetic protein-2 upregulates expression and function of voltage-gated K+ channels in human pul-monary artery smooth muscle cells. Am. J. Physiol. Lung Cell Mol. Physiol. 291, L993-L1004.
-
(2006)
Am. J. Physiol. Lung Cell Mol. Physiol.
, vol.291
-
-
Fantozzi, I.1
Platoshyn, O.2
Wong, A.H.3
Zhang, S.4
Remillard, C.V.5
Fur-tado, M.R.6
Petrauskene, O.V.7
Yuan, J.X.8
-
17
-
-
33645987281
-
Increased expression of type 2 3alpha-hydroxysteroid dehydroge-nase/type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) and its relationship with androgen receptor in prostate carcinoma
-
Fung, K. M., Samara, E. N., Wong, C., Metwalli, A., Krlin, R., Bane, B., Liu, C. Z., Yang, J. T., Pitha, J. V., Culkin, D. J., Kropp, B. P., Penning, T. M., and Lin, H. K. (2006). Increased expression of type 2 3alpha-hydroxysteroid dehydroge-nase/type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) and its relationship with androgen receptor in prostate carcinoma. Endocr. Relat. Cancer 13, 169-180.
-
(2006)
Endocr. Relat. Cancer
, vol.13
, pp. 169-180
-
-
Fung, K.M.1
Samara, E.N.2
Wong, C.3
Metwalli, A.4
Krlin, R.5
Bane, B.6
Liu, C.Z.7
Yang, J.T.8
Pitha, J.V.9
Culkin, D.J.10
Kropp, B.P.11
Penning, T.M.12
Lin, H.K.13
-
18
-
-
79960687149
-
Aldo-keto reductase 1B7 is a target gene of FXR and regulates lipid and glu-cose homeostasis
-
Ge, X., Yin, L., Ma, H., Li, T., Chiang, J. Y., and Zhang, Y. (2011). Aldo-keto reductase 1B7 is a target gene of FXR and regulates lipid and glu-cose homeostasis. J. Lipid Res. 52, 1561-1568.
-
(2011)
J. Lipid Res.
, vol.52
, pp. 1561-1568
-
-
Ge, X.1
Yin, L.2
Ma, H.3
Li, T.4
Chiang, J.Y.5
Zhang, Y.6
-
19
-
-
1642268005
-
SRD5B1 (AKR1D1) gene analysis in delta(4)-3-oxosteroid 5beta-reductase defi-ciency: evidence for primary genetic defect
-
Gonzales, E., Cresteil, D., Baussan, C., Dabadie, A., Gerhardt, M. F., and Jacquemin, E. (2004). SRD5B1 (AKR1D1) gene analysis in delta(4)-3-oxosteroid 5beta-reductase defi-ciency: evidence for primary genetic defect. J. Hepatol. 40, 716-718.
-
(2004)
J. Hepatol.
, vol.40
, pp. 716-718
-
-
Gonzales, E.1
Cresteil, D.2
Baussan, C.3
Dabadie, A.4
Gerhardt, M.F.5
Jacquemin, E.6
-
20
-
-
0036186165
-
Atorvastatin acti-vates PPAR-gamma and attenu-ates the inflammatory response in human monocytes
-
Grip, O., Janciauskiene, S., and Lind-gren, S. (2002). Atorvastatin acti-vates PPAR-gamma and attenu-ates the inflammatory response in human monocytes. Inflamm. Res. 51, 58-62.
-
(2002)
Inflamm. Res.
, vol.51
, pp. 58-62
-
-
Grip, O.1
Janciauskiene, S.2
Lind-gren, S.3
-
21
-
-
79957573421
-
Aldo-keto reductases AKR1C1
-
Hevir, N., Vouk, K., Sinkovec, J., Ribic-Pucelj, M., and Rizner, T. L. (2011). Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metab-olism in ovarian endometriosis. Chem. Biol. Interact. 191, 217-226.
-
(2011)
AKR1C2 and AKR1C3 may enhance progesterone metab-olism in ovarian endometriosis. Chem. Biol. Interact.
, vol.191
, pp. 217-226
-
-
Hevir, N.1
Vouk, K.2
Sinkovec, J.3
Ribic-Pucelj, M.4
Rizner, T.L.5
-
22
-
-
0035866794
-
Overexpression of dihydrodiol dehydrogenase as a prognostic marker of non-small cell lung cancer
-
Hsu, N. Y., Ho, H. C., Chow, K. C., Lin, T. Y., Shih, C. S., Wang, L. S., and Tsai, C. M. (2001). Overexpression of dihydrodiol dehydrogenase as a prognostic marker of non-small cell lung cancer. Cancer Res. 61, 2727-2731.
-
(2001)
Cancer Res
, vol.61
, pp. 2727-2731
-
-
Hsu, N.Y.1
Ho, H.C.2
Chow, K.C.3
Lin, T.Y.4
Shih, C.S.5
Wang, L.S.6
Tsai, C.M.7
-
23
-
-
33746739480
-
Expression of dihydrodiol dehydro-genase and resistance to chemother-apy and radiotherapy in adenocarci-noma cells of lung
-
Hung, J. J., Chow, K. C., Wang, H. W., and Wang, L. S. (2006). Expression of dihydrodiol dehydro-genase and resistance to chemother-apy and radiotherapy in adenocarci-noma cells of lung. Anticancer Res. 26, 2949-2955.
-
(2006)
Anticancer Res
, vol.26
, pp. 2949-2955
-
-
Hung, J.J.1
Chow, K.C.2
Wang, H.W.3
Wang, L.S.4
-
24
-
-
0030821699
-
Comparative anatomy of the aldo-keto reductase superfamily
-
Jez, J. M., Bennett, M. J., Schlegel, B. P., Lewis, M., and Penning, T. M. (1997a). Comparative anatomy of the aldo-keto reductase superfamily. Biochem. J. 326(Pt 3), 625-636.
-
(1997)
Biochem. J.
, vol.326
, Issue.PART 3
, pp. 625-636
-
-
Jez, J.M.1
Bennett, M.J.2
Schlegel, B.P.3
Lewis, M.4
Penning, T.M.5
-
25
-
-
0030876351
-
A new nomenclature for the aldo-keto reductase super-family
-
Jez, J. M., Flynn, T. G., and Penning, T. M. (1997b). A new nomenclature for the aldo-keto reductase super-family. Biochem. Pharmacol. 54, 639-647.
-
(1997)
Biochem. Pharmacol.
, vol.54
, pp. 639-647
-
-
Jez, J.M.1
Flynn, T.G.2
Penning, T.M.3
-
26
-
-
40349112828
-
Transcription factor AP-1 regulates TGF-beta(1)-induced expression of aldose reduc-tase in cultured human mesan-gial cells
-
Jiang, T., Qu, J. J., Nishinaka, T., and Zhang, N. (2008). Transcription factor AP-1 regulates TGF-beta(1)-induced expression of aldose reduc-tase in cultured human mesan-gial cells. Nephrology (Carlton) 13, 212-217.
-
(2008)
Nephrology (Carlton)
, vol.13
, pp. 212-217
-
-
Jiang, T.1
Qu, J.J.2
Nishinaka, T.3
Zhang, N.4
-
27
-
-
79958862747
-
Stereospecific reduction of 5beta-reduced steroids by human ketos-teroid reductases of the AKR (aldo-keto reductase) superfamily: role of AKR1C1-AKR1C4 in the metabo-lism of testosterone and proges-terone via the 5beta-reductase path-way
-
Jin, Y., Mesaros, A. C., Blair, I. A., and Penning, T. M. (2011). Stereospecific reduction of 5beta-reduced steroids by human ketos-teroid reductases of the AKR (aldo-keto reductase) superfamily: role of AKR1C1-AKR1C4 in the metabo-lism of testosterone and proges-terone via the 5beta-reductase path-way. Biochem. J. 437, 53-61.
-
(2011)
Biochem. J.
, vol.437
, pp. 53-61
-
-
Jin, Y.1
Mesaros, A.C.2
Blair, I.A.3
Penning, T.M.4
-
28
-
-
33847021147
-
Aldo-keto reductases and bioactiva-tion/detoxification
-
Jin, Y., and Penning, T. M. (2007). Aldo-keto reductases and bioactiva-tion/detoxification. Annu.Rev.Phar-macol. Toxicol. 47, 263-292.
-
(2007)
Annu. Rev. Phar-macol. Toxicol.
, vol.47
, pp. 263-292
-
-
Jin, Y.1
Penning, T.M.2
-
29
-
-
0030908643
-
Identification and character-ization of multiple osmotic response sequences in the human aldose reductase gene
-
Ko, B. C., Ruepp, B., Bohren, K. M., Gabbay, K. H., and Chung, S. S. (1997). Identification and character-ization of multiple osmotic response sequences in the human aldose reductase gene. J. Biol. Chem. 272, 16431-16437.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 16431-16437
-
-
Ko, B.C.1
Ruepp, B.2
Bohren, K.M.3
Gabbay, K.H.4
Chung, S.S.5
-
30
-
-
77955078547
-
Down-regulation of AKR1B10 gene expres-sion in colorectal cancer
-
Kropotova, E. S., Tychko, R. A., Zinov'Eva, O. L., Zyrianova, A. F., Khankin, S. L., Cherkes, V. L., Aliev, V. A., Beresten, S. F., Oparina, N., and Mashkova, T. D. (2010). Down-regulation of AKR1B10 gene expres-sion in colorectal cancer. Mol. Biol. (Mosk.) 44, 243-250.
-
(2010)
Mol. Biol. (Mosk.)
, vol.44
, pp. 243-250
-
-
Kropotova, E.S.1
Tychko, R.A.2
Zinov'Eva, O.L.3
Zyrianova, A.F.4
Khankin, S.L.5
Cherkes, V.L.6
Aliev, V.A.7
Beresten, S.F.8
Oparina, N.9
Mashkova, T.D.10
-
31
-
-
79954644130
-
Cadmium-induced up-regulation of aldo-keto reductase 1C3 expres-sion in human nasal septum car-cinoma RPMI-2650 cells: involve-ment of reactive oxygen species and phosphatidylinositol 3-kinase/Akt
-
Lee,Y.J.,Lee,G.J.,Baek,B.J.,Heo,S. H., Won, S. Y., Im, J. H., Cho, M. K., Nam, H. S., and Lee, S. H. (2011). Cadmium-induced up-regulation of aldo-keto reductase 1C3 expres-sion in human nasal septum car-cinoma RPMI-2650 cells: involve-ment of reactive oxygen species and phosphatidylinositol 3-kinase/Akt. Environ. Toxicol. Pharmacol. 31, 469-478.
-
(2011)
Environ. Toxicol. Pharmacol.
, vol.31
, pp. 469-478
-
-
Lee, Y.J.1
Lee, G.J.2
Baek, B.J.3
Heo, S.H.4
Won, S.Y.5
Im, J.H.6
Cho, M.K.7
Nam, H.S.8
Lee, S.H.9
-
32
-
-
2942668375
-
Decreased expression of cyclic adenosine monophosphate-regulated aldose reductase (AKR1B1) is associated with malignancy in human sporadic adrenocortical tumors
-
Lefrancois-Martinez, A. M., Bertherat, J., Val, P., Tournaire, C., Gallo-Payet, N., Hyndman, D., Veyssiere, G., Bertagna, X., Jean, C., and Martinez, A. (2004). Decreased expression of cyclic adenosine monophosphate-regulated aldose reductase (AKR1B1) is associated with malignancy in human sporadic adrenocortical tumors. J. Clin. Endocrinol. Metab. 89, 3010-3019.
-
(2004)
J. Clin. Endocrinol. Metab.
, vol.89
, pp. 3010-3019
-
-
Lefrancois-Martinez, A.M.1
Bertherat, J.2
Val, P.3
Tournaire, C.4
Gallo-Payet, N.5
Hyndman, D.6
Veyssiere, G.7
Bertagna, X.8
Jean, C.9
Martinez, A.10
-
33
-
-
0141645554
-
Mutations in SRD5B1 (AKR1D1), the gene encoding delta(4)-3-oxosteroid 5beta-reductase, in hepatitis and liver failure in infancy
-
Lemonde, H. A., Custard, E. J., Bouquet, J., Duran, M., Overmars, H., Scam-bler, P. J., and Clayton, P. T. (2003). Mutations in SRD5B1 (AKR1D1), the gene encoding delta(4)-3-oxosteroid 5beta-reductase, in hepatitis and liver failure in infancy. Gut 52, 1494-1499.
-
(2003)
Gut
, vol.52
, pp. 1494-1499
-
-
Lemonde, H.A.1
Custard, E.J.2
Bouquet, J.3
Duran, M.4
Overmars, H.5
Scam-bler, P.J.6
Clayton, P.T.7
-
34
-
-
67349236706
-
Regulation of AKR1B1 by thyroid hormone and its receptors
-
Liao, C. S., Tai, P. J., Huang, Y. H., Chen, R. N., Wu, S. M., Kuo, L. W., Yeh, C. T., Tsai, M. M., Chen, W. J., and Lin, K. H. (2009). Regulation of AKR1B1 by thyroid hormone and its receptors. Mol. Cell. Endocrinol. 307, 109-117.
-
(2009)
Mol. Cell. Endocrinol.
, vol.307
, pp. 109-117
-
-
Liao, C.S.1
Tai, P.J.2
Huang, Y.H.3
Chen, R.N.4
Wu, S.M.5
Kuo, L.W.6
Yeh, C.T.7
Tsai, M.M.8
Chen, W.J.9
Lin, K.H.10
-
35
-
-
70350778508
-
Aldo-keto reductase fam-ily 1 member B1 inhibitors: old drugs with new perspectives
-
Liu, J., Wen, G., and Cao, D. (2009a). Aldo-keto reductase fam-ily 1 member B1 inhibitors: old drugs with new perspectives. Recent Pat. Anticancer Drug. Discov. 4, 246-253.
-
(2009)
Recent Pat. Anticancer Drug. Discov.
, vol.4
, pp. 246-253
-
-
Liu, J.1
Wen, G.2
Cao, D.3
-
36
-
-
69549088829
-
The aldo-keto reductase Akr1b7 gene is a common transcrip-tional target of xenobiotic recep-tors pregnane X receptor and con-stitutive and rostane receptor
-
Liu, M. J., Takahashi, Y., Wada, T., He, J., Gao, J., Tian, Y., Li, S., and Xie, W. (2009b). The aldo-keto reductase Akr1b7 gene is a common transcrip-tional target of xenobiotic recep-tors pregnane X receptor and con-stitutive and rostane receptor. Mol. Pharmacol. 76, 604-611.
-
(2009)
Mol. Pharmacol.
, vol.76
, pp. 604-611
-
-
Liu, M.J.1
Takahashi, Y.2
Wada, T.3
He, J.4
Gao, J.5
Tian, Y.6
Li, S.7
Xie, W.8
-
37
-
-
33645893202
-
Induction of AKR1C2 by phase II inducers: identifica-tion of a distal consensus antiox-idant response element regulated by NRF2
-
Lou, H., Du, S., Ji, Q., and Stolz, A. (2006). Induction of AKR1C2 by phase II inducers: identifica-tion of a distal consensus antiox-idant response element regulated by NRF2. Mol. Pharmacol. 69, 1662-1672.
-
(2006)
Mol. Pharmacol.
, vol.69
, pp. 1662-1672
-
-
Lou, H.1
Du, S.2
Ji, Q.3
Stolz, A.4
-
38
-
-
33749553527
-
Transcriptosome and serum cytokine profiling of an atypical case of myelodysplas-tic syndrome with progression to acute myelogenous leukemia
-
Mahadevan, D., DiMento, J., Croce, K. D., Riley, C., George, B., Fuchs, D., Mathews, T., Wilson, C., and Lobell, M. (2006). Transcriptosome and serum cytokine profiling of an atypical case of myelodysplas-tic syndrome with progression to acute myelogenous leukemia. Am. J. Hematol. 81, 779-786.
-
(2006)
Am. J. Hematol.
, vol.81
, pp. 779-786
-
-
Mahadevan, D.1
DiMento, J.2
Croce, K.D.3
Riley, C.4
George, B.5
Fuchs, D.6
Mathews, T.7
Wilson, C.8
Lobell, M.9
-
39
-
-
0021846469
-
The sexually differentiated delta 4-3-ketosteroid 5 beta-reductase of rat liver. Purification, characterization, and quantitation
-
Mode, A., and Rafter, I. (1985). The sexually differentiated delta 4-3-ketosteroid 5 beta-reductase of rat liver. Purification, characterization, and quantitation. J. Biol. Chem. 260, 7137-7141.
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 7137-7141
-
-
Mode, A.1
Rafter, I.2
-
40
-
-
33845966779
-
A genome scale location analysis of human Staf/ZNF143-binding sites suggests a widespread role for human Staf/ZNF143 in mammalian promoters
-
Myslinski, E., Gerard, M. A., Krol, A., and Carbon, P. (2006). A genome scale location analysis of human Staf/ZNF143-binding sites suggests a widespread role for human Staf/ZNF143 in mammalian promoters. J. Biol. Chem. 281, 39953-39962.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 39953-39962
-
-
Myslinski, E.1
Gerard, M.A.2
Krol, A.3
Carbon, P.4
-
41
-
-
79957558400
-
Regulation of aldo-keto reductase AKR1B10 gene expression: involvement of tran-scription factor Nrf2
-
Nishinaka, T., Miura, T., Okumura, M., Nakao, F., Nakamura, H., and Terada, T. (2011). Regulation of aldo-keto reductase AKR1B10 gene expression: involvement of tran-scription factor Nrf2. Chem. Biol. Interact. 191, 185-191.
-
(2011)
Chem. Biol. Interact.
, vol.191
, pp. 185-191
-
-
Nishinaka, T.1
Miura, T.2
Okumura, M.3
Nakao, F.4
Nakamura, H.5
Terada, T.6
-
42
-
-
77952887361
-
The CCAAT box binding transcription factor, nuclear factor-Y (NF-Y) regulates transcription of human aldo-keto reductase 1C1 (AKR1C1) gene
-
Pallai, R., Simpkins, H., Chen, J., and Parekh, H. K. (2010). The CCAAT box binding transcription factor, nuclear factor-Y (NF-Y) regulates transcription of human aldo-keto reductase 1C1 (AKR1C1) gene. Gene 459, 11-23.
-
(2010)
Gene
, vol.459
, pp. 11-23
-
-
Pallai, R.1
Simpkins, H.2
Chen, J.3
Parekh, H.K.4
-
43
-
-
78651311728
-
Pro-teomic analysis of cell lines to iden-tify the irinotecan resistance pro-teins
-
Peng, X. C., Gong, F. M., Wei, M., Chen, X., Chen, Y., Cheng, K., Gao, F., Xu, F., Bi, F., and Liu, J. Y. (2010). Pro-teomic analysis of cell lines to iden-tify the irinotecan resistance pro-teins. J. Biosci. 35, 557-564.
-
(2010)
J. Biosci.
, vol.35
, pp. 557-564
-
-
Peng, X.C.1
Gong, F.M.2
Wei, M.3
Chen, X.4
Chen, Y.5
Cheng, K.6
Gao, F.7
Xu, F.8
Bi, F.9
Liu, J.Y.10
-
44
-
-
16444364105
-
AKR1B10: a new diagnostic marker of non-small cell lung carcinoma in smokers
-
Penning, T. M. (2005). AKR1B10: a new diagnostic marker of non-small cell lung carcinoma in smokers. Clin. Cancer Res. 11, 1687-1690.
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 1687-1690
-
-
Penning, T.M.1
-
45
-
-
61649103983
-
Steroid hormone transforming aldo-keto reductases and cancer
-
Penning, T. M., and Byrns, M. C. (2009). Steroid hormone transforming aldo-keto reductases and cancer. Ann. N. Y. Acad. Sci. 1155, 33-42.
-
(2009)
Ann. N. Y. Acad. Sci.
, vol.1155
, pp. 33-42
-
-
Penning, T.M.1
Byrns, M.C.2
-
46
-
-
34547692874
-
Human aldo-keto reductases: func-tion, gene regulation, and single nucleotide polymorphisms
-
Penning, T. M., and Drury, J. E. (2007). Human aldo-keto reductases: func-tion, gene regulation, and single nucleotide polymorphisms. Arch. Biochem. Biophys. 464, 241-250.
-
(2007)
Arch. Biochem. Biophys.
, vol.464
, pp. 241-250
-
-
Penning, T.M.1
Drury, J.E.2
-
47
-
-
78650884359
-
Deletion of the mouse homolog of KCNAB2, a gene linked to monosomy 1p36, results in asso-ciative memory impairments and amygdala hyperexcitability
-
Perkowski, J. J., and Murphy, G. G. (2011). Deletion of the mouse homolog of KCNAB2, a gene linked to monosomy 1p36, results in asso-ciative memory impairments and amygdala hyperexcitability. J. Neu-rosci. 31, 46-54.
-
(2011)
J. Neu-rosci.
, vol.31
, pp. 46-54
-
-
Perkowski, J.J.1
Murphy, G.G.2
-
48
-
-
80054054044
-
Aldose reduc-tase: new insights for an old enzyme
-
Ramana, K. V. (2011). Aldose reduc-tase: new insights for an old enzyme. Biomol. Concepts 2, 103-114.
-
(2011)
Biomol. Concepts
, vol.2
, pp. 103-114
-
-
Ramana, K.V.1
-
49
-
-
84859852987
-
Interleukin 1beta regulates proges-terone metabolism in human cer-vical fibroblasts
-
doi: 10.1177/1933719111419246
-
Roberson, A. E., Hyatt, K., Kenkel, C., Hanson, K., and Myers, D. A. (2011). Interleukin 1beta regulates proges-terone metabolism in human cer-vical fibroblasts. Reprod. Sci. doi: 10.1177/1933719111419246
-
(2011)
Reprod. Sci.
-
-
Roberson, A.E.1
Hyatt, K.2
Kenkel, C.3
Hanson, K.4
Myers, D.A.5
-
50
-
-
67649364171
-
Atorvastatin reduces the expression of aldo-keto reductases in HUVEC and PTEC A new approach to influence the polyol pathway
-
Ruf, T. F., Quintes, S., Sternik, P., and Gottmann, U. (2009). Atorvastatin reduces the expression of aldo-keto reductases in HUVEC and PTEC. A new approach to influence the polyol pathway. Clin. Invest. Med. 32, E219-E228.
-
(2009)
Clin. Invest. Med.
, vol.32
-
-
Ruf, T.F.1
Quintes, S.2
Sternik, P.3
Gottmann, U.4
-
51
-
-
78951477742
-
AKR1B7 is induced by the farnesoid X recep-tor and metabolizes bile acids
-
Schmidt,D. R.,Schmidt,S.,Holmstrom, S. R., Makishima, M.,Yu, R. T., Cum-mins, C. L., Mangelsdorf, D. J., and Kliewer, S. A. (2011). AKR1B7 is induced by the farnesoid X recep-tor and metabolizes bile acids. J. Biol. Chem. 286, 2425-2432.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 2425-2432
-
-
Schmidt, D.R.1
Schmidt, S.2
Holmstrom, S.R.3
Makishima, M.4
Yu, R.T.5
Cum-mins, C.L.6
Mangelsdorf, D.J.7
Kliewer, S.A.8
-
52
-
-
37349121900
-
Transcriptional regulation of aldo-keto reductase 1C1 in HT29 human colon cancer cells resistant to methotrexate: role in the cell cycle and apoptosis
-
Selga, E., Noe, V., and Ciudad, C. J. (2008). Transcriptional regulation of aldo-keto reductase 1C1 in HT29 human colon cancer cells resistant to methotrexate: role in the cell cycle and apoptosis. Biochem. Pharmacol. 75, 414-426.
-
(2008)
Biochem. Pharmacol.
, vol.75
, pp. 414-426
-
-
Selga, E.1
Noe, V.2
Ciudad, C.J.3
-
53
-
-
0000572813
-
Nitric oxide up-regulates aldose reductase expression in rat vascular smooth muscle cells: a potential role for aldose reductase in vascular remodeling
-
Seo, H. G., Nishinaka, T., and Yabe-Nishimura, C. (2000). Nitric oxide up-regulates aldose reductase expression in rat vascular smooth muscle cells: a potential role for aldose reductase in vascular remodeling. Mol. Pharmacol. 57, 709-717.
-
(2000)
Mol. Pharmacol.
, vol.57
, pp. 709-717
-
-
Seo, H.G.1
Nishinaka, T.2
Yabe-Nishimura, C.3
-
54
-
-
80053608290
-
Inhibition of aldose reductase pre-vents endotoxin-induced inflam-mation by regulating the arachi-donic acid pathway in murine macrophages
-
Shoeb, M., Yadav, U. C., Srivastava, S. K., and Ramana, K. V. (2011). Inhibition of aldose reductase pre-vents endotoxin-induced inflam-mation by regulating the arachi-donic acid pathway in murine macrophages. Free Radic. Biol. Med. 51, 1686-1696.
-
(2011)
Free Radic. Biol. Med.
, vol.51
, pp. 1686-1696
-
-
Shoeb, M.1
Yadav, U.C.2
Srivastava, S.K.3
Ramana, K.V.4
-
55
-
-
60249095065
-
Disturbed estrogen and progesterone action in ovarian endometriosis
-
Smuc, T., Hevir, N., Ribic-Pucelj, M., Husen, B., Thole, H., and Rizner, T. L. (2009). Disturbed estrogen and progesterone action in ovarian endometriosis. Mol. Cell. Endocrinol. 301, 59-64.
-
(2009)
Mol. Cell. Endocrinol.
, vol.301
, pp. 59-64
-
-
Smuc, T.1
Hevir, N.2
Ribic-Pucelj, M.3
Husen, B.4
Thole, H.5
Rizner, T.L.6
-
56
-
-
33645056171
-
Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer
-
Stanbrough, M., Bubley, G. J., Ross, K., Golub, T. R., Rubin, M. A., Penning, T. M., Febbo, P. G., and Balk, S. P. (2006). Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer. Cancer Res. 66, 2815-2825.
-
(2006)
Cancer Res
, vol.66
, pp. 2815-2825
-
-
Stanbrough, M.1
Bubley, G.J.2
Ross, K.3
Golub, T.R.4
Rubin, M.A.5
Penning, T.M.6
Febbo, P.G.7
Balk, S.P.8
-
57
-
-
38549100334
-
Regulation of human 3 alpha-hydroxysteroid dehydrogenase (AKR1C4) expres-sion by the liver X receptor alpha
-
Stayrook, K. R., Rogers, P. M., Savkur, R. S., Wang, Y., Su, C., Varga, G., Bu, X., Wei, T., Nagpal, S., Liu, X. S., and Burris, T. P. (2008). Regulation of human 3 alpha-hydroxysteroid dehydrogenase (AKR1C4) expres-sion by the liver X receptor alpha. Mol. Pharmacol. 73, 607-612.
-
(2008)
Mol. Pharmacol.
, vol.73
, pp. 607-612
-
-
Stayrook, K.R.1
Rogers, P.M.2
Savkur, R.S.3
Wang, Y.4
Su, C.5
Varga, G.6
Bu, X.7
Wei, T.8
Nagpal, S.9
Liu, X.S.10
Burris, T.P.11
-
58
-
-
12144291468
-
Regulation of the aldo-keto reductase gene akr1b7 by the nuclear oxysterol receptor LXRalpha (liver X receptor-alpha) in the mouse intestine: putative role of LXRs in lipid detoxifica-tion processes
-
Volle, D. H., Repa, J. J., Mazur, A., Cummins, C. L., Val, P., Henry-Berger, J., Caira, F., Veyssiere, G., Mangelsdorf, D. J., and Lobaccaro, J. M. (2004). Regulation of the aldo-keto reductase gene akr1b7 by the nuclear oxysterol receptor LXRalpha (liver X receptor-alpha) in the mouse intestine: putative role of LXRs in lipid detoxifica-tion processes. Mol. Endocrinol. 18, 888-898.
-
(2004)
Mol. Endocrinol.
, vol.18
, pp. 888-898
-
-
Volle, D.H.1
Repa, J.J.2
Mazur, A.3
Cummins, C.L.4
Val, P.5
Henry-Berger, J.6
Caira, F.7
Veyssiere, G.8
Mangelsdorf, D.J.9
Lobaccaro, J.M.10
-
59
-
-
79751491801
-
Factors responsible for neu-rofibrillary tangles and neuronal cell losses in tauopathy
-
Wakasaya,Y., Kawarabayashi, T., Watan-abe, M., Yamamoto-Watanabe, Y., Takamura, A., Kurata, T., Murakami, T.,Abe,K.,Yamada,K.,Wakabayashi, K., Sasaki, A., Westaway, D., Hyslop, P. S., Matsubara, E., and Shoji, M. (2011). Factors responsible for neu-rofibrillary tangles and neuronal cell losses in tauopathy. J. Neurosci. Res. 89, 576-584.
-
(2011)
J. Neurosci. Res.
, vol.89
, pp. 576-584
-
-
Wakasaya, Y.1
Kawarabayashi, T.2
Watan-abe, M.3
Yamamoto-Watanabe, Y.4
Takamura, A.5
Kurata, T.6
Murakami, T.7
Abe, K.8
Yamada, K.9
Wakabayashi, K.10
Sasaki, A.11
Westaway, D.12
Hyslop, P.S.13
Matsubara, E.14
Shoji, M.15
-
60
-
-
78649884126
-
Smoking-induced upregulation of AKR1B10 expression in the airway epithelium of healthy individuals
-
Wang, R., Wang, G., Ricard, M. J., Fer-ris, B., Strulovici-Barel, Y., Salit, J., Hackett, N. R., Gudas, L. J., and Crystal, R. G. (2010). Smoking-induced upregulation of AKR1B10 expression in the airway epithelium of healthy individuals. Chest 138, 1402-1410.
-
(2010)
Chest
, vol.138
, pp. 1402-1410
-
-
Wang, R.1
Wang, G.2
Ricard, M.J.3
Fer-ris, B.4
Strulovici-Barel, Y.5
Salit, J.6
Hackett, N.R.7
Gudas, L.J.8
Crystal, R.G.9
-
61
-
-
0037330333
-
Up-regulation of aldose reductase by the substrate,methylglyoxal
-
143-144
-
Yabe-Nishimura, C., Nishinaka, T., Iwata, K., and Seo, H. G. (2003). Up-regulation of aldose reductase by the substrate,methylglyoxal. Chem. Biol. Interact. 143-144, 317-323.
-
(2003)
Chem. Biol. Interact.
, pp. 317-323
-
-
Yabe-Nishimura, C.1
Nishinaka, T.2
Iwata, K.3
Seo, H.G.4
-
62
-
-
33745295937
-
Ele-vated activity of transcription factor nuclear factor of activated T-cells 5 (NFAT5) and diabetic nephropathy
-
Yang, B., Hodgkinson, A. D., Oates, P. J., Kwon, H. M., Millward, B. A., and Demaine, A. G. (2006). Ele-vated activity of transcription factor nuclear factor of activated T-cells 5 (NFAT5) and diabetic nephropathy. Diabetes 55, 1450-1455.
-
(2006)
Diabetes
, vol.55
, pp. 1450-1455
-
-
Yang, B.1
Hodgkinson, A.D.2
Oates, P.J.3
Kwon, H.M.4
Millward, B.A.5
Demaine, A.G.6
-
63
-
-
59049088289
-
Impact of smoking cessa-tion on global gene expression in the bronchial epithelium of chronic smokers
-
Zhang, L., Lee, J. J., Tang, H., Fan, Y. H., Xiao, L., Ren, H., Kurie, J., Morice, R. C., Hong, W. K., and Mao, L. (2008). Impact of smoking cessa-tion on global gene expression in the bronchial epithelium of chronic smokers. Cancer Prev. Res. (Phila.) 1, 112-118.
-
(2008)
Cancer Prev. Res. (Phila.)
, vol.1
, pp. 112-118
-
-
Zhang, L.1
Lee, J.J.2
Tang, H.3
Fan, Y.H.4
Xiao, L.5
Ren, H.6
Kurie, J.7
Morice, R.C.8
Hong, W.K.9
Mao, L.10
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