The regulatory circuits for hysteretic switching in cellular signal transduction pathways

FEBS Journal

Volumn 279, Issue 18, 2012, Pages 3329-3337

  Kim, Jeong Rae ^a,b   Cho, Kwang Hyun ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^b University of Seoul   (South Korea)

Author keywords

hysteresis; positive feedback; robustness; signal transduction pathway; switching system

Indexed keywords

AMPLITUDE MODULATION; APOPTOSIS; CELL ACTIVITY; CELL DIFFERENTIATION; CELL FATE; CONFERENCE PAPER; CONTROLLED STUDY; DECISION MAKING; HYSTERESIS; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; MOLECULAR DYNAMICS; MOLECULAR EVOLUTION; POSITIVE FEEDBACK; PRIORITY JOURNAL; RELIABILITY; SIGNAL NOISE RATIO; SIGNAL TRANSDUCTION; SPIKE; STIMULUS RESPONSE;

COMPUTER SIMULATION; FEEDBACK, PHYSIOLOGICAL; MODELS, BIOLOGICAL; SIGNAL TRANSDUCTION;

EID: 84865968816     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2012.08623.x     Document Type: Conference Paper

References (37)

1. Sedra AS, &, Smith KC, (1998) Microelectronic Circuits, 4th edn. Oxford University Press, New York.
2. Lim M, &, Saloma C, (2002) Emergence of hysteresis in a network of nonhysteretic agents with continuous responses. Phys Rev Lett 88, 038701.
3. Barkai N, &, Leibler S, (2000) Circadian clocks limited by noise. Nature 403, 267-268. (Pubitemid 30062374)
4. Kim JR, Bae WS, Yoon Y, &, Cho KH, (2007) Topological difference of core regulatory networks induces different entrainment characteristics of plant and animal circadian clocks. Biophys J 93, L1-L3.
5. Han Z, Yang L, MacLellan WR, Weiss JN, &, Qu Z, (2005) Hysteresis and cell cycle transitions: how crucial is it? Biophys J 88, 1626-1634. (Pubitemid 40976179)
6. Solomon MJ, (2003) Hysteresis meets the cell cycle. Proc Natl Acad Sci USA 100, 771-772. (Pubitemid 36183904)
7. Li FT, Long T, Lu Y, Ouyang Q, &, Tang C, (2004) The yeast cell-cycle network is robustly designed. Proc Natl Acad Sci USA 101, 4781-4786. (Pubitemid 38469154)
8. Tyson JJ, &, Novak B, (2001) Regulation of the eukaryotic cell cycle: molecular antagonism, hysteresis, and irreversible transitions. J Theor Biol 210, 249-263. (Pubitemid 32575064)
9. Pomerening JR, Kim SY, &, Ferrell JE Jr, (2005) Systems-level dissection of the cell-cycle oscillator: bypassing positive feedback produces damped oscillations. Cell 122, 565-578. (Pubitemid 41191155)
10. Pomerening JR, Sontag ED, &, Ferrell JE Jr, (2003) Building a cell cycle oscillator: hysteresis and bistability in the activation of Cdc2. Nat Cell Biol 5, 346-351. (Pubitemid 36432300)
11. Bagowski CP, Besser J, Frey CR, &, Ferrell JE Jr, (2003) The JNK cascade as a biochemical switch in mammalian cells: ultrasensitive and all-or-none responses. Curr Biol 13, 315-320. (Pubitemid 36230022)
12. Bagowski CP, &, Ferrell JE Jr, (2001) Bistability in the JNK cascade. Curr Biol 11, 1176-1182. (Pubitemid 32722570)
13. Ferrell JE Jr, &, Machleder EM, (1998) The biochemical basis of an all-or-none cell fate switch in Xenopus oocytes. Science 280, 895-898. (Pubitemid 28215598)
14. Ferrell JE Jr, Pomerening JR, Kim SY, Trunnell NB, Xiong W, Huang CY, &, Machleder EM, (2009) Simple, realistic models of complex biological processes: positive feedback and bistability in a cell fate switch and a cell cycle oscillator. FEBS Lett 583, 3999-4005.
15. Yates A, Callard R, &, Stark J, (2004) Combining cytokine signalling with T-bet and GATA-3 regulation in Th1 and Th2 differentiation: a model for cellular decision-making. J Theor Biol 231, 181-196. (Pubitemid 39221871)
16. Mendoza L, (2006) A network model for the control of the differentiation process in Th cells. Biosystems 84, 101-114. (Pubitemid 43670489)
17. Acar M, Becskei A, &, van Oudenaarden A, (2005) Enhancement of cellular memory by reducing stochastic transitions. Nature 435, 228-232. (Pubitemid 40685951)
18. Caron AZ, Chaloux B, Arguin G, &, Guillemette G, (2007) Protein kinase C decreases the apparent affinity of the inositol 1,4,5-trisphosphate receptor type 3 in RINm5F cells. Cell Calcium 42, 323-331. (Pubitemid 47074403)
19. Grueter CE, Colbran RJ, &, Anderson ME, (2007) CaMKII, an emerging molecular driver for calcium homeostasis, arrhythmias, and cardiac dysfunction. J Mol Med 85, 5-14. (Pubitemid 46020938)
20. Fukami K, (2002) Structure, regulation, and function of phospholipase C isozymes. J Biochem 131, 293-299. (Pubitemid 34292818)
21. Kusters JMAM, Cortes JM, van Meerwijk WPM, Ypey DL, Theuvenet APR, &, Gielen CCAM, (2007) Hysteresis and bistability in a realistic cell model for calcium oscillations and action potential firing. Phys Rev Lett 98, 098107, doi:10.1103/PhysRevLett.98.098107. (Pubitemid 46353969)
22. Xiong W, &, Ferrell JE Jr, (2003) A positive-feedback-based bistable 'memory module' that governs a cell fate decision. Nature 426, 460-465. (Pubitemid 37490134)
23. Kim JR, Yoon Y, &, Cho KH, (2008) Coupled feedback loops form dynamic motifs of cellular networks. Biophys J 94, 359-365.
24. Rao CV, Wolf DM, &, Arkin AP, (2002) Control, exploitation and tolerance of intracellular noise. Nature 420, 231-237. (Pubitemid 35340135)
25. Kurata H, Masaki K, Sumida Y, &, Iwasaki R, (2005) CADLIVE dynamic simulator: direct link of biochemical networks to dynamic models. Genome Res 15, 590-600. (Pubitemid 41057822)
26. Chang HH, Oh PY, Ingber DE, &, Huang S, (2006) Multistable and multistep dynamics in neutrophil differentiation. BMC Cell Biol 7, 11.
27. Ozbudak EM, Thattai M, Lim HN, Shraiman BI, &, Van Oudenaarden A, (2004) Multistability in the lactose utilization network of Escherichia coli. Nature 427, 737-740. (Pubitemid 38294592)
28. Cohn M, &, Horibata K, (1959) Inhibition by glucose of the induced synthesis of the beta-galactoside-enzyme system of Escherichia coli. Analysis of maintenance. J Bacteriol 78, 601-612.
29. Keeler JD, Pichler EE, &, Ross J, (1989) Noise in neural networks: thresholds, hysteresis, and neuromodulation of signal-to-noise. Proc Natl Acad Sci USA 86, 1712-1716. (Pubitemid 19078971)
30. Brewer KK, Sakai H, Alencar AM, Majumdar A, Arold SP, Lutchen KR, Ingenito EP, &, Suki B, (2003) Lung and alveolar wall elastic and hysteretic behavior in rats: effects of in vivo elastase treatment. J Appl Physiol 95, 1926-1936. (Pubitemid 37310377)
31. Kim D, Kolch W, &, Cho KH, (2009) Multiple roles of the NF-kappaB signaling pathway regulated by coupled negative feedback circuits. FASEB J 23, 2796-2802.
32. Kim D, Kwon YK, &, Cho KH, (2007) Coupled positive and negative feedback circuits form an essential building block of cellular signaling pathways. BioEssays 29, 85-90. (Pubitemid 46188100)
33. Kwon YK, &, Cho KH, (2007) Boolean dynamics of biological networks with multiple coupled feedback loops. Biophys J 92, 2975-2981.
34. Kwon YK, &, Cho KH, (2007) Analysis of feedback loops and robustness in network evolution based on Boolean models. BMC Bioinformatics 8, 430.
35. Brandman O, Ferrett JE, Li R, &, Meyer T, (2005) Interlinked fast and slow positive feedback loops drive reliable cell decisions. Science 310, 496-498. (Pubitemid 41507964)
36. Ferrell JE, (2008) Feedback regulation of opposing enzymes generates robust, all-or-more bistable responses. Curr Biol 18, R244-R245.
37. Wang LM, Xin J, &, Nie Q, (2010) A critical quantity for noise attenuation in feedback systems. PLoS Comput Biol 6, e1000764.