메뉴 건너뛰기




Volumn 47, Issue 1, 2009, Pages 23-31

Cardiac cell-cell junctions in health and disease: Electrical versus mechanical coupling

Author keywords

Adherens junction; Arrhythmia; ARVD C; Cx43; Desmosome; Gap junction; Heart; Intercalated disc; Plakophilin

Indexed keywords

DESMIN; DESMOPLAKIN; NERVE CELL ADHESION MOLECULE; PLAKOGLOBIN; PLAKOPHILIN; PROTEIN ZO1;

EID: 67349247486     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2009.03.016     Document Type: Review
Times cited : (158)

References (91)
  • 1
    • 0000805743 scopus 로고
    • Über die Leitung der Erregung im Herzmuskel
    • Engelmann T.W. Über die Leitung der Erregung im Herzmuskel. Pflugers Arch. 11 (1875) 465-480
    • (1875) Pflugers Arch. , vol.11 , pp. 465-480
    • Engelmann, T.W.1
  • 2
    • 0001376159 scopus 로고
    • The electrical constants of Purkinje fibers
    • Weidmann S. The electrical constants of Purkinje fibers. J. Physiol. 118 (1952) 348-360
    • (1952) J. Physiol. , vol.118 , pp. 348-360
    • Weidmann, S.1
  • 3
    • 4243405438 scopus 로고
    • Electron microscopy of the intercalated disc of cardiac muscle
    • Söstrand F.S., and Andersson E. Electron microscopy of the intercalated disc of cardiac muscle. Experientia 10 (1954) 369-370
    • (1954) Experientia , vol.10 , pp. 369-370
    • Söstrand, F.S.1    Andersson, E.2
  • 4
    • 0005082313 scopus 로고
    • Intercalated discs in heart muscle studied with the electron microscope
    • van Breemen V.L. Intercalated discs in heart muscle studied with the electron microscope. Anat. Rec. 117 (1953) 49-63
    • (1953) Anat. Rec. , vol.117 , pp. 49-63
    • van Breemen, V.L.1
  • 5
    • 0001683386 scopus 로고
    • Propagation of action potentials and the structure of the nexus in cardiac muscle
    • Barr L., Dewey M.M., and Berger W. Propagation of action potentials and the structure of the nexus in cardiac muscle. J. Gen. Physiol. 48 (1965) 797-823
    • (1965) J. Gen. Physiol. , vol.48 , pp. 797-823
    • Barr, L.1    Dewey, M.M.2    Berger, W.3
  • 6
    • 0023848617 scopus 로고
    • Right ventricular cardiomyopathy and sudden death in young people
    • Thiene G., Nava A., Corrado D., Rossi L., and Pennelli N. Right ventricular cardiomyopathy and sudden death in young people. N. Engl. J. Med. 318 (1988) 129-133
    • (1988) N. Engl. J. Med. , vol.318 , pp. 129-133
    • Thiene, G.1    Nava, A.2    Corrado, D.3    Rossi, L.4    Pennelli, N.5
  • 7
    • 0030712343 scopus 로고    scopus 로고
    • Spectrum of clinicopathologic manifestations of arrhythmogenic right ventricular cardiomyopathy/dysplasia: a multicenter study
    • Corrado D., Basso C., Thiene G., McKenna W.J., Davies M.J., Fontaliran F., et al. Spectrum of clinicopathologic manifestations of arrhythmogenic right ventricular cardiomyopathy/dysplasia: a multicenter study. J. Am. Coll. Cardiol. 30 (1997) 1512-1520
    • (1997) J. Am. Coll. Cardiol. , vol.30 , pp. 1512-1520
    • Corrado, D.1    Basso, C.2    Thiene, G.3    McKenna, W.J.4    Davies, M.J.5    Fontaliran, F.6
  • 9
    • 0037089088 scopus 로고    scopus 로고
    • Remodeling the intercalated disc leads to cardiomyopathy in mice misexpressing cadherins in the heart
    • Ferreira-Cornwell M.C., Luo Y., Narula N., Lenox J.M., Lieberman M., and Radice G.L. Remodeling the intercalated disc leads to cardiomyopathy in mice misexpressing cadherins in the heart. J. Cell. Sci. 115 (2002) 1623-1634
    • (2002) J. Cell. Sci. , vol.115 , pp. 1623-1634
    • Ferreira-Cornwell, M.C.1    Luo, Y.2    Narula, N.3    Lenox, J.M.4    Lieberman, M.5    Radice, G.L.6
  • 10
    • 35348841509 scopus 로고    scopus 로고
    • Tight junctions/adherens junctions: basic structure and function
    • Niessen C.M. Tight junctions/adherens junctions: basic structure and function. J. Invest. Dermatol. 127 (2007) 2525-2532
    • (2007) J. Invest. Dermatol. , vol.127 , pp. 2525-2532
    • Niessen, C.M.1
  • 11
    • 0000752197 scopus 로고
    • Junctional complexes in various epithelia
    • Farquhar M.G., and Palade G.E. Junctional complexes in various epithelia. J. Cell Biol. 17 (1963) 375-412
    • (1963) J. Cell Biol. , vol.17 , pp. 375-412
    • Farquhar, M.G.1    Palade, G.E.2
  • 12
    • 70449205317 scopus 로고
    • The fine structure of the interrelationship of cells in the human epidermis
    • Odland G.F. The fine structure of the interrelationship of cells in the human epidermis. J. Biophys. Biochem. Cytol. 4 (1958) 529-538
    • (1958) J. Biophys. Biochem. Cytol. , vol.4 , pp. 529-538
    • Odland, G.F.1
  • 13
    • 0014544626 scopus 로고
    • Ultrastructure of desmosomes in mammalian intercalated disc; appearances after lanthanum treatment
    • Rayns D.G., Simpson F.O., and Ledingham J.M. Ultrastructure of desmosomes in mammalian intercalated disc; appearances after lanthanum treatment. J. Cell Biol. 42 (1969) 322-326
    • (1969) J. Cell Biol. , vol.42 , pp. 322-326
    • Rayns, D.G.1    Simpson, F.O.2    Ledingham, J.M.3
  • 14
    • 39849097562 scopus 로고    scopus 로고
    • Desmosome structure, composition and function
    • Garrod D., and Chidgey M. Desmosome structure, composition and function. Biochim. Biophys. Acta 1778 (2008) 572-587
    • (2008) Biochim. Biophys. Acta , vol.1778 , pp. 572-587
    • Garrod, D.1    Chidgey, M.2
  • 15
    • 0028915946 scopus 로고
    • Specific permeability and selective formation of gap junction channels in connexin-transfected HeLa cells
    • Elfgang C., Eckert R., Lichtenberg-Fraté H., Butterweck A., Traub O., Klein R.A., et al. Specific permeability and selective formation of gap junction channels in connexin-transfected HeLa cells. J. Cell Biol. 129 (1995) 805-817
    • (1995) J. Cell Biol. , vol.129 , pp. 805-817
    • Elfgang, C.1    Eckert, R.2    Lichtenberg-Fraté, H.3    Butterweck, A.4    Traub, O.5    Klein, R.A.6
  • 16
    • 0030028301 scopus 로고    scopus 로고
    • The gap junction communication channel
    • Kumar N.M., and Gilula N.B. The gap junction communication channel. Cell 84 (1996) 381-388
    • (1996) Cell , vol.84 , pp. 381-388
    • Kumar, N.M.1    Gilula, N.B.2
  • 17
    • 0035985057 scopus 로고    scopus 로고
    • Structural and functional diversity of connexin genes in the mouse and human genome
    • Willecke K., Eiberger J., Degen J., Eckardt D., Romualdi A., Guldenagel M., et al. Structural and functional diversity of connexin genes in the mouse and human genome. Biol. Chem. 383 (2002) 725-737
    • (2002) Biol. Chem. , vol.383 , pp. 725-737
    • Willecke, K.1    Eiberger, J.2    Degen, J.3    Eckardt, D.4    Romualdi, A.5    Guldenagel, M.6
  • 18
    • 33744471185 scopus 로고    scopus 로고
    • Gap junctions and propagation of the cardiac action potential
    • Bernstein S.A., and Morley G.E. Gap junctions and propagation of the cardiac action potential. Adv. Cardiol. 42 (2006) 71-85
    • (2006) Adv. Cardiol. , vol.42 , pp. 71-85
    • Bernstein, S.A.1    Morley, G.E.2
  • 19
    • 0021139243 scopus 로고
    • Two configurations of a channel-forming membrane protein
    • Unwin P.N.T., and Ennis P.D. Two configurations of a channel-forming membrane protein. Nature 307 (1984) 609-612
    • (1984) Nature , vol.307 , pp. 609-612
    • Unwin, P.N.T.1    Ennis, P.D.2
  • 20
    • 0017640572 scopus 로고
    • Gap junction structures. II. Analysis of the X-ray diffraction data
    • Makowski L., Caspar D.L., Phillips W.C., and Goodenough D.A. Gap junction structures. II. Analysis of the X-ray diffraction data. J. Cell Biol. 74 (1977) 629-645
    • (1977) J. Cell Biol. , vol.74 , pp. 629-645
    • Makowski, L.1    Caspar, D.L.2    Phillips, W.C.3    Goodenough, D.A.4
  • 21
    • 1942438964 scopus 로고    scopus 로고
    • Gap junctions and the connexin protein family
    • Sohl G., and Willecke K. Gap junctions and the connexin protein family. Cardiovasc. Res. 62 (2004) 228-232
    • (2004) Cardiovasc. Res. , vol.62 , pp. 228-232
    • Sohl, G.1    Willecke, K.2
  • 22
    • 0031012580 scopus 로고    scopus 로고
    • Three-dimensional structure of the gap junction connexon
    • Perkins G., Goodenough D., and Sosinsky G. Three-dimensional structure of the gap junction connexon. Biophys. J. 72 (1997) 533-544
    • (1997) Biophys. J. , vol.72 , pp. 533-544
    • Perkins, G.1    Goodenough, D.2    Sosinsky, G.3
  • 23
    • 0023551497 scopus 로고
    • Connexin43: a protein from rat heart homologous to a gap junction protein from liver
    • Beyer E.C., Paul D.L., and Goodenough D.A. Connexin43: a protein from rat heart homologous to a gap junction protein from liver. J. Cell Biol. 105 (1987) 2621-2629
    • (1987) J. Cell Biol. , vol.105 , pp. 2621-2629
    • Beyer, E.C.1    Paul, D.L.2    Goodenough, D.A.3
  • 24
    • 0024356206 scopus 로고
    • The 43-kD polypeptide of heart gap junctions: immunolocalization (I), topology (II), and functional domains (III)
    • Yancey S.B., John S.A., Lal R., Austin B.J., and Revel J.P. The 43-kD polypeptide of heart gap junctions: immunolocalization (I), topology (II), and functional domains (III). J. Cell Biol. 108 (1989) 2241-2254
    • (1989) J. Cell Biol. , vol.108 , pp. 2241-2254
    • Yancey, S.B.1    John, S.A.2    Lal, R.3    Austin, B.J.4    Revel, J.P.5
  • 26
    • 0024510255 scopus 로고
    • Distribution and three-dimensional structure of intercellular junctions in canine myocardium
    • Hoyt R.H., Cohen M.L., and Saffitz J.E. Distribution and three-dimensional structure of intercellular junctions in canine myocardium. Circ. Res. 64 (1989) 563-574
    • (1989) Circ. Res. , vol.64 , pp. 563-574
    • Hoyt, R.H.1    Cohen, M.L.2    Saffitz, J.E.3
  • 27
    • 0025159130 scopus 로고
    • The cardiac gap junction and intercalated disc
    • Severs N.J. The cardiac gap junction and intercalated disc. Int. J. Cardiol. 26 (1990) 137-173
    • (1990) Int. J. Cardiol. , vol.26 , pp. 137-173
    • Severs, N.J.1
  • 28
    • 0024761888 scopus 로고
    • Gap junction shape and orientation at the cardiac intercalated disk
    • Severs N.J. Gap junction shape and orientation at the cardiac intercalated disk. Circ. Res. 65 (1989) 1458-1462
    • (1989) Circ. Res. , vol.65 , pp. 1458-1462
    • Severs, N.J.1
  • 29
    • 38949159633 scopus 로고    scopus 로고
    • Arrhythmogenic right ventricular cardiomyopathy/dysplasia
    • Thiene G., Corrado D., and Basso C. Arrhythmogenic right ventricular cardiomyopathy/dysplasia. Orphanet. J. Rare Dis. 2 (2007) 45
    • (2007) Orphanet. J. Rare Dis. , vol.2 , pp. 45
    • Thiene, G.1    Corrado, D.2    Basso, C.3
  • 32
    • 18644363134 scopus 로고    scopus 로고
    • Mutation in human desmoplakin domain binding to plakoglobin causes a dominant form of arrhythmogenic right ventricular cardiomyopathy
    • Rampazzo A., Nava A., Malacrida S., Beffagna G., Bauce B., Rossi V., et al. Mutation in human desmoplakin domain binding to plakoglobin causes a dominant form of arrhythmogenic right ventricular cardiomyopathy. Am. J. Hum. Genet. 71 (2002) 1200-1206
    • (2002) Am. J. Hum. Genet. , vol.71 , pp. 1200-1206
    • Rampazzo, A.1    Nava, A.2    Malacrida, S.3    Beffagna, G.4    Bauce, B.5    Rossi, V.6
  • 33
    • 35348913125 scopus 로고    scopus 로고
    • A novel dominant mutation in plakoglobin causes arrhythmogenic right ventricular cardiomyopathy
    • Asimaki A., Syrris P., Wichter T., Matthias P., Saffitz J.E., and McKenna W.J. A novel dominant mutation in plakoglobin causes arrhythmogenic right ventricular cardiomyopathy. Am. J. Hum. Genet. 81 (2007) 964-973
    • (2007) Am. J. Hum. Genet. , vol.81 , pp. 964-973
    • Asimaki, A.1    Syrris, P.2    Wichter, T.3    Matthias, P.4    Saffitz, J.E.5    McKenna, W.J.6
  • 34
    • 11444264507 scopus 로고    scopus 로고
    • Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy
    • Gerull B., Heuser A., Wichter T., Paul M., Basson C.T., McDermott D.A., et al. Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy. Nat. Genet. 36 (2004) 1162-1164
    • (2004) Nat. Genet. , vol.36 , pp. 1162-1164
    • Gerull, B.1    Heuser, A.2    Wichter, T.3    Paul, M.4    Basson, C.T.5    McDermott, D.A.6
  • 35
    • 33645772930 scopus 로고    scopus 로고
    • Plakophilin-2 mutations are the major determinant of familial arrhythmogenic right ventricular dysplasia/cardiomyopathy
    • van Tintelen J.P., Entius M.M., Bhuiyan Z.A., Jongbloed R., Wiesfeld A.C., Wilde A.A., et al. Plakophilin-2 mutations are the major determinant of familial arrhythmogenic right ventricular dysplasia/cardiomyopathy. Circulation 113 (2006) 1650-1658
    • (2006) Circulation , vol.113 , pp. 1650-1658
    • van Tintelen, J.P.1    Entius, M.M.2    Bhuiyan, Z.A.3    Jongbloed, R.4    Wiesfeld, A.C.5    Wilde, A.A.6
  • 37
    • 33751073197 scopus 로고    scopus 로고
    • Arrhythmogenic right ventricular dysplasia/cardiomyopathy associated with mutations in the desmosomal gene desmocollin-2
    • Syrris P., Ward D., Evans A., Asimaki A., Gandjbakhch E., Sen-Chowdhry S., et al. Arrhythmogenic right ventricular dysplasia/cardiomyopathy associated with mutations in the desmosomal gene desmocollin-2. Am. J. Hum. Genet. 79 (2006) 978-984
    • (2006) Am. J. Hum. Genet. , vol.79 , pp. 978-984
    • Syrris, P.1    Ward, D.2    Evans, A.3    Asimaki, A.4    Gandjbakhch, E.5    Sen-Chowdhry, S.6
  • 38
    • 33645527574 scopus 로고    scopus 로고
    • Mutations in desmoglein-2 gene are associated with arrhythmogenic right ventricular cardiomyopathy
    • Pilichou K., Nava A., Basso C., Beffagna G., Bauce B., Lorenzon A., et al. Mutations in desmoglein-2 gene are associated with arrhythmogenic right ventricular cardiomyopathy. Circulation 113 (2006) 1171-1179
    • (2006) Circulation , vol.113 , pp. 1171-1179
    • Pilichou, K.1    Nava, A.2    Basso, C.3    Beffagna, G.4    Bauce, B.5    Lorenzon, A.6
  • 40
    • 77449145091 scopus 로고    scopus 로고
    • Abnormal connexin43 in arrhythmogenic right ventricular cardiomyopathy caused by plakophilin-2 mutations
    • Fidler L.M., Wilson G.J., Liu F., Cui X., Scherer S.W., Taylor G.P., et al. Abnormal connexin43 in arrhythmogenic right ventricular cardiomyopathy caused by plakophilin-2 mutations. J. Cell. Mol. Med. (2008)
    • (2008) J. Cell. Mol. Med.
    • Fidler, L.M.1    Wilson, G.J.2    Liu, F.3    Cui, X.4    Scherer, S.W.5    Taylor, G.P.6
  • 41
    • 34548253988 scopus 로고    scopus 로고
    • Molecular composition of the intercalated disc in a spontaneous canine animal model of arrhythmogenic right ventricular dysplasia/cardiomyopathy
    • Oxford E.M., Everitt M., Coombs W., Fox P.R., Kraus M., Gelzer A.R., et al. Molecular composition of the intercalated disc in a spontaneous canine animal model of arrhythmogenic right ventricular dysplasia/cardiomyopathy. Heart Rhythm 4 (2007) 1196-1205
    • (2007) Heart Rhythm , vol.4 , pp. 1196-1205
    • Oxford, E.M.1    Everitt, M.2    Coombs, W.3    Fox, P.R.4    Kraus, M.5    Gelzer, A.R.6
  • 42
    • 1542619239 scopus 로고    scopus 로고
    • Arrhythmogenic right ventricular cardiomyopathy causing sudden cardiac death in boxer dogs: a new animal model of human disease
    • Basso C., Fox P.R., Meurs K.M., Towbin J.A., Spier A.W., Calabrese F., et al. Arrhythmogenic right ventricular cardiomyopathy causing sudden cardiac death in boxer dogs: a new animal model of human disease. Circulation 109 (2004) 1180-1185
    • (2004) Circulation , vol.109 , pp. 1180-1185
    • Basso, C.1    Fox, P.R.2    Meurs, K.M.3    Towbin, J.A.4    Spier, A.W.5    Calabrese, F.6
  • 43
    • 0031024666 scopus 로고    scopus 로고
    • Dissociated spatial patterning of gap junctions and cell adhesion junctions during postnatal differentiation of ventricular myocardium
    • Angst B.D., Khan L.U., Severs N.J., Whitely K., Rothery S., Thompson R.P., et al. Dissociated spatial patterning of gap junctions and cell adhesion junctions during postnatal differentiation of ventricular myocardium. Circ. Res. 80 (1997) 88-94
    • (1997) Circ. Res. , vol.80 , pp. 88-94
    • Angst, B.D.1    Khan, L.U.2    Severs, N.J.3    Whitely, K.4    Rothery, S.5    Thompson, R.P.6
  • 44
    • 0033597942 scopus 로고    scopus 로고
    • Spatiotemporal development and distribution of intercellular junctions in adult rat cardiomyocytes in culture
    • Kostin S., Hein S., Bauer E.P., and Schaper J. Spatiotemporal development and distribution of intercellular junctions in adult rat cardiomyocytes in culture. Circ. Res. 85 (1999) 154-167
    • (1999) Circ. Res. , vol.85 , pp. 154-167
    • Kostin, S.1    Hein, S.2    Bauer, E.P.3    Schaper, J.4
  • 45
    • 0028093157 scopus 로고
    • Spatiotemporal relation between gap junctions and fascia adherens junctions during postnatal development of human ventricular myocardium
    • Peters N.S., Severs N.J., Rothery S.M., Lincoln C., Yacoub M.H., and Green C.R. Spatiotemporal relation between gap junctions and fascia adherens junctions during postnatal development of human ventricular myocardium. Circulation 90 (1994) 713-725
    • (1994) Circulation , vol.90 , pp. 713-725
    • Peters, N.S.1    Severs, N.J.2    Rothery, S.M.3    Lincoln, C.4    Yacoub, M.H.5    Green, C.R.6
  • 46
    • 0033607553 scopus 로고    scopus 로고
    • Remodeling of cell-cell and cell-extracellular matrix interactions at the border zone of rat myocardial infarcts
    • Matsushita T., Oyamada M., Fujimoto K., Yasuda Y., Masuda S., Wada Y., et al. Remodeling of cell-cell and cell-extracellular matrix interactions at the border zone of rat myocardial infarcts. Circ. Res. 85 (1999) 1046-1055
    • (1999) Circ. Res. , vol.85 , pp. 1046-1055
    • Matsushita, T.1    Oyamada, M.2    Fujimoto, K.3    Yasuda, Y.4    Masuda, S.5    Wada, Y.6
  • 47
    • 0034682933 scopus 로고    scopus 로고
    • Pulsatile stretch remodels cell-to-cell communication in cultured myocytes
    • Zhuang J., Yamada K.A., Saffitz J.E., and Kleber A.G. Pulsatile stretch remodels cell-to-cell communication in cultured myocytes. Circ. Res. 87 (2000) 316-322
    • (2000) Circ. Res. , vol.87 , pp. 316-322
    • Zhuang, J.1    Yamada, K.A.2    Saffitz, J.E.3    Kleber, A.G.4
  • 48
    • 24044533528 scopus 로고    scopus 로고
    • Distinct pathways regulate expression of cardiac electrical and mechanical junction proteins in response to stretch
    • Yamada K., Green K.G., Samarel A.M., and Saffitz J.E. Distinct pathways regulate expression of cardiac electrical and mechanical junction proteins in response to stretch. Circ. Res. 97 (2005) 346-353
    • (2005) Circ. Res. , vol.97 , pp. 346-353
    • Yamada, K.1    Green, K.G.2    Samarel, A.M.3    Saffitz, J.E.4
  • 49
    • 33646107862 scopus 로고    scopus 로고
    • Dysregulation of cell adhesion proteins and cardiac arrhythmogenesis
    • Li J., Patel V.V., and Radice G.L. Dysregulation of cell adhesion proteins and cardiac arrhythmogenesis. Clin. Med. Res. 4 (2006) 42-52
    • (2006) Clin. Med. Res. , vol.4 , pp. 42-52
    • Li, J.1    Patel, V.V.2    Radice, G.L.3
  • 50
    • 0029160437 scopus 로고
    • Morphogenetic roles of classic cadherins
    • Takeichi M. Morphogenetic roles of classic cadherins. Curr. Opin. Cell Biol. 7 (1995) 619-627
    • (1995) Curr. Opin. Cell Biol. , vol.7 , pp. 619-627
    • Takeichi, M.1
  • 51
    • 1942503184 scopus 로고    scopus 로고
    • Gap junctions and connexin-interacting proteins
    • Giepmans B.N. Gap junctions and connexin-interacting proteins. Cardiovasc. Res. 62 (2004) 233-245
    • (2004) Cardiovasc. Res. , vol.62 , pp. 233-245
    • Giepmans, B.N.1
  • 53
    • 24744444972 scopus 로고    scopus 로고
    • Cardiac-specific loss of N-cadherin leads to alteration in connexins with conduction slowing and arrhythmogenesis
    • Li J., Patel V.V., Kostetskii I., Xiong Y., Chu A.F., Jacobson J.T., et al. Cardiac-specific loss of N-cadherin leads to alteration in connexins with conduction slowing and arrhythmogenesis. Circ. Res. 97 (2005) 474-481
    • (2005) Circ. Res. , vol.97 , pp. 474-481
    • Li, J.1    Patel, V.V.2    Kostetskii, I.3    Xiong, Y.4    Chu, A.F.5    Jacobson, J.T.6
  • 54
    • 14044256554 scopus 로고    scopus 로고
    • Induced deletion of the N-cadherin gene in the heart leads to dissolution of the intercalated disc structure
    • Kostetskii I., Li J., Xiong Y., Zhou R., Ferrari V.A., Patel V.V., et al. Induced deletion of the N-cadherin gene in the heart leads to dissolution of the intercalated disc structure. Circ. Res. 96 (2005) 346-354
    • (2005) Circ. Res. , vol.96 , pp. 346-354
    • Kostetskii, I.1    Li, J.2    Xiong, Y.3    Zhou, R.4    Ferrari, V.A.5    Patel, V.V.6
  • 55
    • 40649116404 scopus 로고    scopus 로고
    • N-cadherin haploinsufficiency affects cardiac gap junctions and arrhythmic susceptibility
    • Li J., Levin M.D., Xiong Y., Petrenko N., Patel V.V., and Radice G.L. N-cadherin haploinsufficiency affects cardiac gap junctions and arrhythmic susceptibility. J. Mol. Cell. Cardiol. 44 (2008) 597-606
    • (2008) J. Mol. Cell. Cardiol. , vol.44 , pp. 597-606
    • Li, J.1    Levin, M.D.2    Xiong, Y.3    Petrenko, N.4    Patel, V.V.5    Radice, G.L.6
  • 56
    • 35548987124 scopus 로고    scopus 로고
    • Desmosomes from a structural perspective
    • Stokes D.L. Desmosomes from a structural perspective. Curr. Opin. Cell Biol. 19 (2007) 565-571
    • (2007) Curr. Opin. Cell Biol. , vol.19 , pp. 565-571
    • Stokes, D.L.1
  • 57
    • 5444235947 scopus 로고    scopus 로고
    • Requirement of plakophilin 2 for heart morphogenesis and cardiac junction formation
    • Grossmann K.S., Grund C., Huelsken J., Behrend M., Erdmann B., Franke W.W., et al. Requirement of plakophilin 2 for heart morphogenesis and cardiac junction formation. J. Cell Biol. 167 (2004) 149-160
    • (2004) J. Cell Biol. , vol.167 , pp. 149-160
    • Grossmann, K.S.1    Grund, C.2    Huelsken, J.3    Behrend, M.4    Erdmann, B.5    Franke, W.W.6
  • 58
    • 44449156929 scopus 로고    scopus 로고
    • The area composita of adhering junctions connecting heart muscle cells of vertebrates. V. The importance of plakophilin-2 demonstrated by small interference RNA-mediated knockdown in cultured rat cardiomyocytes
    • Pieperhoff S., Schumacher H., and Franke W.W. The area composita of adhering junctions connecting heart muscle cells of vertebrates. V. The importance of plakophilin-2 demonstrated by small interference RNA-mediated knockdown in cultured rat cardiomyocytes. Eur. J. Cell Biol. 87 (2008) 399-411
    • (2008) Eur. J. Cell Biol. , vol.87 , pp. 399-411
    • Pieperhoff, S.1    Schumacher, H.2    Franke, W.W.3
  • 59
    • 34848820956 scopus 로고    scopus 로고
    • Connexin43 remodeling caused by inhibition of plakophilin-2 expression in cardiac cells
    • Oxford E.M., Musa H., Maass K., Coombs W., Taffet S.M., and Delmar M. Connexin43 remodeling caused by inhibition of plakophilin-2 expression in cardiac cells. Circ. Res. 101 (2007) 703-711
    • (2007) Circ. Res. , vol.101 , pp. 703-711
    • Oxford, E.M.1    Musa, H.2    Maass, K.3    Coombs, W.4    Taffet, S.M.5    Delmar, M.6
  • 61
    • 10144229330 scopus 로고    scopus 로고
    • Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart
    • Ruiz P., Brinkmann V., Ledermann B., Behrend M., Grund C., Thalhammer C., et al. Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart. J. Cell Biol. 135 (1996) 215-225
    • (1996) J. Cell Biol. , vol.135 , pp. 215-225
    • Ruiz, P.1    Brinkmann, V.2    Ledermann, B.3    Behrend, M.4    Grund, C.5    Thalhammer, C.6
  • 62
    • 33750539318 scopus 로고    scopus 로고
    • Age- and training-dependent development of arrhythmogenic right ventricular cardiomyopathy in heterozygous plakoglobin-deficient mice
    • Kirchhof P., Fabritz L., Zwiener M., Witt H., Schafers M., Zellerhoff S., et al. Age- and training-dependent development of arrhythmogenic right ventricular cardiomyopathy in heterozygous plakoglobin-deficient mice. Circulation 114 (2006) 1799-1806
    • (2006) Circulation , vol.114 , pp. 1799-1806
    • Kirchhof, P.1    Fabritz, L.2    Zwiener, M.3    Witt, H.4    Schafers, M.5    Zellerhoff, S.6
  • 64
    • 2442509624 scopus 로고    scopus 로고
    • Remodeling of myocyte gap junctions in arrhythmogenic right ventricular cardiomyopathy due to a deletion in plakoglobin (Naxos disease)
    • Kaplan S.R., Gard J.J., Protonotarios N., Tsatsopoulou A., Spiliopoulou C., Anastasakis A., et al. Remodeling of myocyte gap junctions in arrhythmogenic right ventricular cardiomyopathy due to a deletion in plakoglobin (Naxos disease). Heart Rhythm 1 (2004) 3-11
    • (2004) Heart Rhythm , vol.1 , pp. 3-11
    • Kaplan, S.R.1    Gard, J.J.2    Protonotarios, N.3    Tsatsopoulou, A.4    Spiliopoulou, C.5    Anastasakis, A.6
  • 65
    • 33748741625 scopus 로고    scopus 로고
    • Desmosomal dysfunction due to mutations in desmoplakin causes arrhythmogenic right ventricular dysplasia/cardiomyopathy
    • Yang Z., Bowles N.E., Scherer S.E., Taylor M.D., Kearney D.L., Ge S., et al. Desmosomal dysfunction due to mutations in desmoplakin causes arrhythmogenic right ventricular dysplasia/cardiomyopathy. Circ. Res. 99 (2006) 646-655
    • (2006) Circ. Res. , vol.99 , pp. 646-655
    • Yang, Z.1    Bowles, N.E.2    Scherer, S.E.3    Taylor, M.D.4    Kearney, D.L.5    Ge, S.6
  • 67
    • 33748753687 scopus 로고    scopus 로고
    • Arrhythmogenic right ventricular dysplasia, a cell adhesion cardiomyopathy: insights into disease pathogenesis from preliminary genotype-phenotype assessment
    • Tsatsopoulou A.A., Protonotarios N.I., and McKenna W.J. Arrhythmogenic right ventricular dysplasia, a cell adhesion cardiomyopathy: insights into disease pathogenesis from preliminary genotype-phenotype assessment. Heart 92 (2006) 1720-1723
    • (2006) Heart , vol.92 , pp. 1720-1723
    • Tsatsopoulou, A.A.1    Protonotarios, N.I.2    McKenna, W.J.3
  • 69
    • 0032751526 scopus 로고    scopus 로고
    • The absence of desmin leads to cardiomyocyte hypertrophy and cardiac dilation with compromised systolic function
    • Milner D.J., Taffet G.E., Wang X., Pham T., Tamura T., Hartley C., et al. The absence of desmin leads to cardiomyocyte hypertrophy and cardiac dilation with compromised systolic function. J. Mol. Cell. Cardiol. 31 (1999) 2063-2076
    • (1999) J. Mol. Cell. Cardiol. , vol.31 , pp. 2063-2076
    • Milner, D.J.1    Taffet, G.E.2    Wang, X.3    Pham, T.4    Tamura, T.5    Hartley, C.6
  • 70
    • 22544475951 scopus 로고    scopus 로고
    • Remodeling of gap junctions and slow conduction in a mouse model of desmin-related cardiomyopathy
    • Gard J.J., Yamada K., Green K.G., Eloff B.C., Rosenbaum D.S., Wang X., et al. Remodeling of gap junctions and slow conduction in a mouse model of desmin-related cardiomyopathy. Cardiovasc. Res. 67 (2005) 539-547
    • (2005) Cardiovasc. Res. , vol.67 , pp. 539-547
    • Gard, J.J.1    Yamada, K.2    Green, K.G.3    Eloff, B.C.4    Rosenbaum, D.S.5    Wang, X.6
  • 71
    • 0032557460 scopus 로고    scopus 로고
    • Direct association of the gap junction protein connexin-43 with ZO-1 in cardiac myocytes
    • Toyofuku T., Yabuki M., Otsu K., Kuzuya T., Hori M., and Tada M. Direct association of the gap junction protein connexin-43 with ZO-1 in cardiac myocytes. J. Biol. Chem. 273 (1998) 12725-12731
    • (1998) J. Biol. Chem. , vol.273 , pp. 12725-12731
    • Toyofuku, T.1    Yabuki, M.2    Otsu, K.3    Kuzuya, T.4    Hori, M.5    Tada, M.6
  • 73
    • 0037155043 scopus 로고    scopus 로고
    • Increased association of ZO-1 with connexin43 during remodeling of cardiac gap junctions
    • Barker R.J., Price R.L., and Gourdie R.G. Increased association of ZO-1 with connexin43 during remodeling of cardiac gap junctions. Circ. Res. 90 (2002) 317-324
    • (2002) Circ. Res. , vol.90 , pp. 317-324
    • Barker, R.J.1    Price, R.L.2    Gourdie, R.G.3
  • 75
    • 0037348756 scopus 로고    scopus 로고
    • The organization of adherens junctions and desmosomes at the cardiac intercalated disc is independent of gap junctions
    • Gutstein D.E., Liu F.Y., Meyers M.B., Choo A., and Fishman G.I. The organization of adherens junctions and desmosomes at the cardiac intercalated disc is independent of gap junctions. J. Cell. Sci. 116 (2003) 875-885
    • (2003) J. Cell. Sci. , vol.116 , pp. 875-885
    • Gutstein, D.E.1    Liu, F.Y.2    Meyers, M.B.3    Choo, A.4    Fishman, G.I.5
  • 78
    • 33646678437 scopus 로고    scopus 로고
    • A novel GJA 1 mutation in oculo-dento-digital dysplasia with curly hair and hyperkeratosis
    • Kelly S.C., Ratajczak P., Keller M., Purcell S.M., Griffin T., and Richard G. A novel GJA 1 mutation in oculo-dento-digital dysplasia with curly hair and hyperkeratosis. Eur. J. Dermatol. 16 (2006) 241-245
    • (2006) Eur. J. Dermatol. , vol.16 , pp. 241-245
    • Kelly, S.C.1    Ratajczak, P.2    Keller, M.3    Purcell, S.M.4    Griffin, T.5    Richard, G.6
  • 79
    • 56549116154 scopus 로고    scopus 로고
    • Fate of connexin43 in cardiac tissue harbouring a disease-linked connexin43 mutant
    • Manias J.L., Plante I., Gong X.Q., Shao Q., Churko J., Bai D., et al. Fate of connexin43 in cardiac tissue harbouring a disease-linked connexin43 mutant. Cardiovasc. Res. 80 (2008) 385-395
    • (2008) Cardiovasc. Res. , vol.80 , pp. 385-395
    • Manias, J.L.1    Plante, I.2    Gong, X.Q.3    Shao, Q.4    Churko, J.5    Bai, D.6
  • 80
    • 0035858885 scopus 로고    scopus 로고
    • Alterations at the intercalated disk associated with the absence of muscle LIM protein
    • Ehler E., Horowits R., Zuppinger C., Price R.L., Perriard E., Leu M., et al. Alterations at the intercalated disk associated with the absence of muscle LIM protein. J. Cell Biol. 153 (2001) 763-772
    • (2001) J. Cell Biol. , vol.153 , pp. 763-772
    • Ehler, E.1    Horowits, R.2    Zuppinger, C.3    Price, R.L.4    Perriard, E.5    Leu, M.6
  • 81
    • 0033083390 scopus 로고    scopus 로고
    • Chronic pressure overload cardiac hypertrophy and failure in guinea pigs: III. Intercalated disc remodeling
    • Wang X., and Gerdes A.M. Chronic pressure overload cardiac hypertrophy and failure in guinea pigs: III. Intercalated disc remodeling. J. Mol. Cell. Cardiol. 31 (1999) 333-343
    • (1999) J. Mol. Cell. Cardiol. , vol.31 , pp. 333-343
    • Wang, X.1    Gerdes, A.M.2
  • 82
    • 51749110724 scopus 로고    scopus 로고
    • Remodelling of gap junctions and connexin expression in diseased myocardium
    • Severs N.J., Bruce A.F., Dupont E., and Rothery S. Remodelling of gap junctions and connexin expression in diseased myocardium. Cardiovasc. Res. 80 (2008) 9-19
    • (2008) Cardiovasc. Res. , vol.80 , pp. 9-19
    • Severs, N.J.1    Bruce, A.F.2    Dupont, E.3    Rothery, S.4
  • 83
    • 0034812869 scopus 로고    scopus 로고
    • The role of myocardial gap junctions in electrical conduction and arrhythmogenesis
    • Kanno S., and Saffitz J.E. The role of myocardial gap junctions in electrical conduction and arrhythmogenesis. Cardiovasc. Pathol. 10 (2001) 169-177
    • (2001) Cardiovasc. Pathol. , vol.10 , pp. 169-177
    • Kanno, S.1    Saffitz, J.E.2
  • 84
    • 1642315375 scopus 로고    scopus 로고
    • Effects of mechanical forces and mediators of hypertrophy on remodeling of gap junctions in the heart
    • Saffitz J.E., and Kleber A.G. Effects of mechanical forces and mediators of hypertrophy on remodeling of gap junctions in the heart. Circ. Res. 94 (2004) 585-591
    • (2004) Circ. Res. , vol.94 , pp. 585-591
    • Saffitz, J.E.1    Kleber, A.G.2
  • 85
    • 50949118037 scopus 로고    scopus 로고
    • Transmural dispersion of refractoriness and conduction velocity is associated with heterogeneously reduced connexin43 in a rabbit model of heart failure
    • Wiegerinck R.F., van Veen T.A., Belterman C.N., Schumacher C.A., Noorman M., de Bakker J.M., et al. Transmural dispersion of refractoriness and conduction velocity is associated with heterogeneously reduced connexin43 in a rabbit model of heart failure. Heart Rhythm 5 (2008) 1178-1185
    • (2008) Heart Rhythm , vol.5 , pp. 1178-1185
    • Wiegerinck, R.F.1    van Veen, T.A.2    Belterman, C.N.3    Schumacher, C.A.4    Noorman, M.5    de Bakker, J.M.6
  • 86
    • 4944249400 scopus 로고    scopus 로고
    • Mechanisms underlying conduction slowing and arrhythmogenesis in nonischemic dilated cardiomyopathy
    • Akar F.G., Spragg D.D., Tunin R.S., Kass D.A., and Tomaselli G.F. Mechanisms underlying conduction slowing and arrhythmogenesis in nonischemic dilated cardiomyopathy. Circ. Res. 95 (2004) 717-725
    • (2004) Circ. Res. , vol.95 , pp. 717-725
    • Akar, F.G.1    Spragg, D.D.2    Tunin, R.S.3    Kass, D.A.4    Tomaselli, G.F.5
  • 87
    • 1942534677 scopus 로고    scopus 로고
    • Connexin 43 expression and distribution in compensated and decompensated cardiac hypertrophy in patients with aortic stenosis
    • Kostin S., Dammer S., Hein S., Klovekorn W.P., Bauer E.P., and Schaper J. Connexin 43 expression and distribution in compensated and decompensated cardiac hypertrophy in patients with aortic stenosis. Cardiovasc. Res. 62 (2004) 426-436
    • (2004) Cardiovasc. Res. , vol.62 , pp. 426-436
    • Kostin, S.1    Dammer, S.2    Hein, S.3    Klovekorn, W.P.4    Bauer, E.P.5    Schaper, J.6
  • 88
    • 27944464983 scopus 로고    scopus 로고
    • Left ventricular histomorphometric findings in dogs with heart failure treated with the Acorn Cardiac Support Device
    • Sharov V.G., Todor A.V., and Sabbah H.N. Left ventricular histomorphometric findings in dogs with heart failure treated with the Acorn Cardiac Support Device. Heart Fail. Rev. 10 (2005) 141-147
    • (2005) Heart Fail. Rev. , vol.10 , pp. 141-147
    • Sharov, V.G.1    Todor, A.V.2    Sabbah, H.N.3
  • 89
    • 0034724944 scopus 로고    scopus 로고
    • Remodeling of gap junctional coupling in hypertrophied right ventricles of rats with monocrotaline-induced pulmonary hypertension
    • Uzzaman M., Honjo H., Takagishi Y., Emdad L., Magee A.I., Severs N.J., et al. Remodeling of gap junctional coupling in hypertrophied right ventricles of rats with monocrotaline-induced pulmonary hypertension. Circ. Res. 86 (2000) 871-878
    • (2000) Circ. Res. , vol.86 , pp. 871-878
    • Uzzaman, M.1    Honjo, H.2    Takagishi, Y.3    Emdad, L.4    Magee, A.I.5    Severs, N.J.6
  • 90
    • 34548170429 scopus 로고    scopus 로고
    • Zonula occludens-1 and connexin 43 expression in the failing human heart
    • Kostin S. Zonula occludens-1 and connexin 43 expression in the failing human heart. J. Cell. Mol. Med. 11 (2007) 892-895
    • (2007) J. Cell. Mol. Med. , vol.11 , pp. 892-895
    • Kostin, S.1
  • 91
    • 39749165131 scopus 로고    scopus 로고
    • Gap junction remodelling in human heart failure is associated with increased interaction of connexin43 with ZO-1
    • Bruce A.F., Rothery S., Dupont E., and Severs N.J. Gap junction remodelling in human heart failure is associated with increased interaction of connexin43 with ZO-1. Cardiovasc. Res. 77 (2008) 757-765
    • (2008) Cardiovasc. Res. , vol.77 , pp. 757-765
    • Bruce, A.F.1    Rothery, S.2    Dupont, E.3    Severs, N.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.