Clonally expanded mitochondrial DNA deletions within the choroid plexus in multiple sclerosis

Acta Neuropathologica

Volumn 124, Issue 2, 2012, Pages 209-220

  Campbell, Graham R ^a,b   Kraytsberg, Yevgenya ^c   Krishnan, Kim J ^a   Ohno, Nobuhiko ^d   Ziabreva, Iryna ^a   Reeve, Amy ^a   Trapp, Bruce D ^d   Newcombe, Jia ^e   Reynolds, Richard ^f   Lassmann, Hans ^g   Khrapko, Konstantin ^c   Turnbull, Doug M ^a   Mahad, Don J ^a,b,d  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c HARVARD MEDICAL SCHOOL   (United States)

^d LERNER RESEARCH INSTITUTE   (United States)

^e UNIVERSITY COLLEGE LONDON   (United Kingdom)

^f IMPERIAL COLLEGE LONDON   (United Kingdom)

^g MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Choroid plexus; Clonal expansion; Mitochondrial DNA; Multiple sclerosis

Indexed keywords

CYTOCHROME C OXIDASE; MITOCHONDRIAL DNA; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE);

ALZHEIMER DISEASE; ARTICLE; BRAIN MITOCHONDRION; CELL ENERGY; CHOROID PLEXUS; CLINICAL ARTICLE; CLONAL EXPANSION; COMPLEX I DEFICIENCY; CONTROLLED STUDY; CYTOCHROME C OXIDASE DEFICIENCY; DEMYELINATION; ENCEPHALITIS; GENE DELETION; HUMAN; HUMAN CELL; HUMAN TISSUE; MOLECULAR GENETICS; MULTIPLE SCLEROSIS; NEUROPATHOLOGY; PARKINSON DISEASE; PRIORITY JOURNAL;

ALZHEIMER DISEASE; BRAIN; CHOROID PLEXUS; DNA, MITOCHONDRIAL; HUMANS; MULTIPLE SCLEROSIS; NEURONS; SEQUENCE DELETION;

EID: 84865861273     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-012-1001-9     Document Type: Article

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