In silico based structural analysis of some piperidine analogs as farnesyltransferase inhibitors

Medicinal Chemistry

Volumn 8, Issue 5, 2012, Pages 853-864

  Moorthy, Narayana Subbiah Hari Narayana ^a   Sousa, Sergio F ^a   Ramos, Maria J ^a   Fernandes, Pedro A ^a  

^a UNIVERSITY OF PORTO   (Portugal)

Author keywords

Farnesyltransferase; Piperidine; QSAR; vdW Surface area

Indexed keywords

ANTINEOPLASTIC AGENT; PIPERIDINE DERIVATIVE; PROTEIN FARNESYLTRANSFERASE INHIBITOR;

ARTICLE; COMPUTER MODEL; DRUG ANALYSIS; HYDROPHILICITY; HYDROPHOBICITY; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

COMPUTER SIMULATION; ENZYME INHIBITORS; FARNESYLTRANSTRANSFERASE; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PIPERIDINES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RESEARCH DESIGN; SOLUBILITY; STATIC ELECTRICITY; THERMODYNAMICS;

EID: 84865803335     PISSN: 15734064     EISSN: 18756638     Source Type: Journal    
DOI: 10.2174/157340612802084171     Document Type: Article

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