QSAR studies of cytotoxic acridine 5,7-diones: A comparative study using P-VSA descriptors and topological descriptors

Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry

Volumn 46, Issue 1, 2007, Pages 177-184

  Moorthy, N S Hari Narayana ^b   Karthikeyan, C ^a   Trivedi, Piyush ^a  

^a SHRI G S INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

^b Rajiv Gandhi Proudyogiki Vishwavidyalaya   (India)

Author keywords

Acridine 5,7 diones; Anticancer; P VSA descriptors; QSAR

Indexed keywords

EID: 34548307212     PISSN: 03764699     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Oprea T I, J Braz Chem Soc, 13, 2002, 811.
2. Lin A, QuaSAR-descriptors, Journal of Chemical Computing Group http://www.chemcomp.com/Journal_of_CCG/Features/descr.htm
3. Estrada E, Perdomo-Lo'pez I & Torres-Labandeira J , J Chem Inf Comput Sci, 41, 2001, 1561.
4. Labute P, J Mol Graphics Mod, 18, 2000, 464.
5. Baurin N, Mozziconacci J C, Arnoult E, Chavatte P, Marot C & Morin-Allory L, J Chem Inf Comput Sci, 44, 2004, 276.
6. Denny W A, Expert Opin Invest Drugs, 17, 1997, 43.
7. Read M, Harrison R J, Romagnoli B, Tanious F A, Gowan S H, Reszka A P, Wilson W D, Kelland L R & Neidle S, Proc Natl Acad Sci USA, 98, 2001, 4844.
8. Balaji S, Karthikeyan C, Moorthy N S H N & Trivedi P, Bioorg Med Chem Lett, 14, 2004, 6089.
9. Antonini I, Polucci P, Magnano A, Gatto B, Palumbo M, Menta E, Pescalli N & Martelli S, J Med Chem, 45, 2002, 696.
10. Debnath B, Gayen S, Bhattacharya S, Samanta S & Jha T, Bioorg Med Chem, 11, 2003, 5493.
11. Mazerska Z, Augustin E, Dziegielewski J, Cholody M W & Konopa J, Anticancer Drug Des, 1, 1996, 73.
12. Thakur A, Thakur M, Kakani N, Joshi A, Thakur S & Gupta S, ARKIVOC, 14, 2004, 36.
13. MOE is a molecular modeling package developed by Chemical Computing Group Inc, Canada.
14. Dragon web version 3.0 -2003, Milano Chemometrics and QSAR research Group, www.disat.uinmib.it.
15. Maybridge Chemical Company Ltd., Cornwall, PL34 OHW, England, http://www.maybridge.co.uk.
16. Graph Theory in Chemistry, Encyclopedia of Computational Chemistry, Edited: Ivanciuc O & Balaban A T, Vol 2, Paul von Rague Schyler, (John Wiley & Sons, New York), 1997, pp 1169-1190.
17. Konstantinova' E V, Skorobogatov V A & Vidyuk M V, Indian J Chem, 42A, 2003, 1277.
18. Estrada E, Patlewicz G & Uriarte E, Indian J Chem, 42A, 2003, 1315.
19. SYSTAT 10.2 is a statistical package developed by SYSTAT Software Inc, USA.
20. Cho D H, Lee S K, Kim B T & No K T, Bull Korean Chem Soc, 22, 2001, 388.
21. VALSTAT is a statistical program developed by Dr. Arun Kumar Gupta, SGSlTS, Indore.
22. Kier L B & Hall L H, Eur J Med Chem - Chimica Therapeutica, 12, 1977, 307.
23. Balaban A T, Pure Appl Chem, 55, 1983, 199.