The DEAD-Box RNA helicase Dbp5 functions in translation termination

Science

Volumn 315, Issue 5812, 2007, Pages 646-649

  Gross, Thomas ^a   Siepmann, Anja ^a   Sturm, Dorotheé ^a   Windgassen, Merle ^a,d   Scarcelli, John J ^b   Seedorf, Matthias ^c   Cole, Charles N ^b   Krebber, Heike ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOHEXIMIDE; DBP5 PROTEIN; DEAD BOX PROTEIN; GLUCOSE; GREEN FLUORESCENT PROTEIN; HYGROMYCIN B; MESSENGER RNA; PAROMOMYCIN; PEPTONE; POLYADENYLIC ACID BINDING PROTEIN; TRANSFER RNA; UNCLASSIFIED DRUG;

ENZYME ACTIVITY; GENETIC ANALYSIS; PROTEIN; RNA;

ARTICLE; ENZYME ACTIVITY; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN RNA BINDING; RNA TRANSLATION; SACCHAROMYCES CEREVISIAE; TRANSLATION REGULATION; TRANSLATION TERMINATION; YEAST;

CODON, TERMINATOR; DEAD-BOX RNA HELICASES; MUTATION; NUCLEOCYTOPLASMIC TRANSPORT PROTEINS; PEPTIDE CHAIN TERMINATION, TRANSLATIONAL; PEPTIDE TERMINATION FACTORS; POLY(A)-BINDING PROTEINS; POLYRIBOSOMES; RNA HELICASES; RNA STABILITY; RNA, FUNGAL; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EUKARYOTA; SACCHAROMYCES CEREVISIAE;

EID: 33846837482     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1134641     Document Type: Article

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14. We are grateful to M. Ashe, D. M. Bedwell, T.-H. Chang, P. Linder, R. Lill, R. Parker, P. A. Silver, G. Stahl, F. Stutz, M. Tuite, and G. Zhouravleva for antibodies, strains, and plasmids; H. Bastians for critical reading; and R. Müller and B. Dobberstein for support. This work was funded by a grant from NIH to C.N.C. and grants from Kempkes, Manchot, and the Deutsche Forschungsgemeinschaft to H.K.