Inhibitory effect of TNF-α and IL-8 secretion by pimarane-type diterpenoids from acanthopanax koreanum

Chemical and Pharmaceutical Bulletin

Volumn 51, Issue 5, 2003, Pages 605-607

  Cai, Xing Fu ^a   Shen, Guanghai ^a   Dat, Nguyen Tien ^a   Kang, Ok Hwa ^b   Kim, Jin A ^b   Lee, Young Mi ^b   Lee, Jung Joon ^c   Kim, Young Ho ^a  

^a Chungnam National University   (South Korea)

^b Wonkwang University   (South Korea)

^c Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

Acanthopanax koreanum; Diterpenoid; IL 8; Inhibitory effect; TNF

Indexed keywords

ACANTHOIC ACID; ACANTHOKOREOIC ACID A; ACANTHOL; ACANTHOPANAX KOREANUM EXTRACT; DITERPENE; DITERPENOID; INTERLEUKIN 8; PIMARANE; PLANT EXTRACT; SUMOGASIDE; TRYPSIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ABIETANE DERIVATIVE;

ACANTHOPANAX KOREANUM; ARTICLE; CELL LINE; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DRUG ISOLATION; HUMAN; HUMAN CELL; MEDICINAL PLANT; PROTEIN SECRETION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ACANTHOPANAX; CELL STRAIN HT29; CHEMISTRY; DRUG ANTAGONISM; ENZYME LINKED IMMUNOSORBENT ASSAY; FAST ATOM BOMBARDMENT MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INFRARED SPECTROPHOTOMETRY; ISOLATION AND PURIFICATION; KOREA; MAST CELL; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLANT ROOT;

ACANTHOPANAX; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DITERPENES; DITERPENES, ABIETANE; ENZYME-LINKED IMMUNOSORBENT ASSAY; HT29 CELLS; HUMANS; INTERLEUKIN-8; KOREA; MAGNETIC RESONANCE SPECTROSCOPY; MAST CELLS; PLANT ROOTS; SPECTROMETRY, MASS, FAST ATOM BOMBARDMENT; SPECTROPHOTOMETRY, INFRARED; TRYPSIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0642309816     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.51.605     Document Type: Article

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