Integrin-Mediated Mechanotransduction Pathway of Low-Intensity Continuous Ultrasound in Human Chondrocytes

Ultrasound in Medicine and Biology

Volumn 38, Issue 10, 2012, Pages 1734-1743

  Whitney, Nicholas P ^a   Lamb, Allyson C ^a   Louw, Tobias M ^a   Subramanian, Anuradha ^a  

^a UNIVERSITY OF NEBRASKA LINCOLN   (United States)

Author keywords

Chondrocyte; CrkII; Extracellular regulated kinase (Erk); Focal adhesion kinase (FAK); Integrin; Mechanotransduction; P130 Crk associated substrate (p130Cas); Src; Ultrasound

Indexed keywords

CHONDROCYTES; CRKII; EXTRACELLULAR-REGULATED KINASE; FOCAL ADHESION KINASE; INTEGRINS; MECHANOTRANSDUCTION; P130 CRK-ASSOCIATED SUBSTRATE (P130CAS); SRC;

ADHESION; ANTIBODIES; BODY FLUIDS; CELL CULTURE; ENZYME ACTIVITY; GENES; PHOSPHORYLATION; STRESSES; ULTRASONIC APPLICATIONS; ULTRASONICS;

SIGNAL TRANSDUCTION;

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 AMINO 7 TERT BUTYL 5 (4 METHYLPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; FOCAL ADHESION KINASE; INTEGRIN; INTEGRIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOPROTEIN; PROTEIN CRK2; PROTEIN P130; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG;

ARTICLE; CARTILAGE CELL; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR SIGNALING; LOW INTENSITY CONTINUOUS ULTRASOUND; MECHANOTRANSDUCTION; PRIORITY JOURNAL; ULTRASOUND THERAPY; WESTERN BLOTTING;

CELLS, CULTURED; CHONDROCYTES; DOSE-RESPONSE RELATIONSHIP, RADIATION; HUMANS; INTEGRINS; MAP KINASE SIGNALING SYSTEM; MECHANOTRANSDUCTION, CELLULAR; RADIATION DOSAGE; SONICATION;

EID: 84865778435     PISSN: 03015629     EISSN: 1879291X     Source Type: Journal    
DOI: 10.1016/j.ultrasmedbio.2012.06.002     Document Type: Article

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