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Volumn 90, Issue 1, 1996, Pages 61-71

Effects of intermittent pressure-induced strain on the electrophysiology of cultured human chondrocytes: Evidence for the presence of stretch-activated membrane ion channels

Author keywords

Articular; Cartilage; Cells; Ion channels; Mechanoreceptors; Membrane potential

Indexed keywords

AMILORIDE; APAMIN; CADMIUM CHLORIDE; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM ION; CHARYBDOTOXIN; CYCLIC AMP; GADOLINIUM; IBERIOTOXIN; ION CHANNEL; POTASSIUM CHANNEL; PROTEOGLYCAN; SOMATOSTATIN; THAPSIGARGIN;

EID: 0030032790     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/cs0900061     Document Type: Article
Times cited : (158)

References (67)
  • 1
    • 0026746381 scopus 로고
    • Articular cartilage thickness and glycosaminoglycan distribution in the canine knee joint after strenuous (20km/day) running exercise
    • Kiviranta I, Tammi M, Jurvelin J, Aroneski J, Saamanen A-M, Helminen HJ. Articular cartilage thickness and glycosaminoglycan distribution in the canine knee joint after strenuous (20km/day) running exercise. Clin Orthop 1992; 283: 302-8.
    • (1992) Clin Orthop , vol.283 , pp. 302-308
    • Kiviranta, I.1    Tammi, M.2    Jurvelin, J.3    Aroneski, J.4    Saamanen, A.-M.5    Helminen, H.J.6
  • 2
    • 0026057522 scopus 로고
    • The effects of hydrostatic pressure on matrix synthesis in articular cartilage
    • Hall AC, Urban JPG, Gehl KA. The effects of hydrostatic pressure on matrix synthesis in articular cartilage. J Orthop Res 1991; 9: 1-10.
    • (1991) J Orthop Res , vol.9 , pp. 1-10
    • Hall, A.C.1    Urban, J.P.G.2    Gehl, K.A.3
  • 3
    • 0015041419 scopus 로고
    • A study of the effect of experimental immobilisation on rabbit articular cartilage
    • Sood SC. A study of the effect of experimental immobilisation on rabbit articular cartilage. J Anat 1971; 108: 497-507.
    • (1971) J Anat , vol.108 , pp. 497-507
    • Sood, S.C.1
  • 4
    • 0025513751 scopus 로고
    • Proteoglycan alterations following immobilization and remobilization in the articular cartilage of young canine knee (stifle) joint
    • Saamaren A-M, Tammi M, Jurvelin J, Kiviranta I, Helminen HJ. Proteoglycan alterations following immobilization and remobilization in the articular cartilage of young canine knee (stifle) joint. J Orthop Res 1990; 8: 863-73.
    • (1990) J Orthop Res , vol.8 , pp. 863-873
    • Saamaren, A.-M.1    Tammi, M.2    Jurvelin, J.3    Kiviranta, I.4    Helminen, H.J.5
  • 5
    • 0023913279 scopus 로고
    • Moderate running exercise augments glycosaminoglycans and thickness of articular cartilage in the knee joint of young Beagle dogs
    • Kiviranta I, Tammi M, Jarvelinj J, Saamanen A-M, Helminen HJ. Moderate running exercise augments glycosaminoglycans and thickness of articular cartilage in the knee joint of young Beagle dogs. J Orthop Res 1968; 6: 188-95.
    • (1968) J Orthop Res , vol.6 , pp. 188-195
    • Kiviranta, I.1    Tammi, M.2    Jarvelinj, J.3    Saamanen, A.-M.4    Helminen, H.J.5
  • 6
    • 0023203154 scopus 로고
    • Weight bearing controls glycosaminoglycan concentrations and articular cartilage thickness in the knee joints of young Beagle dogs
    • Kiviranta I, Jurvelin J, Tamimi M, Saamanen A-M, Helminen HJ. Weight bearing controls glycosaminoglycan concentrations and articular cartilage thickness in the knee joints of young Beagle dogs. Arthritis Rheum 1987; 30: 801-9.
    • (1987) Arthritis Rheum , vol.30 , pp. 801-809
    • Kiviranta, I.1    Jurvelin, J.2    Tamimi, M.3    Saamanen, A.-M.4    Helminen, H.J.5
  • 7
    • 0002125217 scopus 로고
    • The effects of static and dynamic compression on matrix metabolism in cartilage explants
    • Kuettner KE, Schleyerbach R, Peyron JG, Hascall VC, eds. New York; Raven Press
    • Sah RL, Grodzinski AJ, Plaas AKH, Sandy J. The effects of static and dynamic compression on matrix metabolism in cartilage explants. In: Kuettner KE, Schleyerbach R, Peyron JG, Hascall VC, eds. Articular cartilage and osteoarthritis. New York; Raven Press, 1992: 373-92.
    • (1992) Articular Cartilage and Osteoarthritis , pp. 373-392
    • Sah, R.L.1    Grodzinski, A.J.2    Plaas, A.K.H.3    Sandy, J.4
  • 8
    • 0018403958 scopus 로고
    • In vitro studies of the effect of intermittent compressive forces on cartilage cell proliferation
    • Veldhuijzen JP, Bourret LA, Rodan GA. In vitro studies of the effect of intermittent compressive forces on cartilage cell proliferation. J Cell Physiol 1979; 98: 299-306.
    • (1979) J Cell Physiol , vol.98 , pp. 299-306
    • Veldhuijzen, J.P.1    Bourret, L.A.2    Rodan, G.A.3
  • 9
    • 0003005633 scopus 로고
    • Cartilage and chondrocyte responses to mechanical loading in vitro
    • Helminen HJ, ed. Bristol: Wright
    • Van Kampen GPJ, Van der Stadt RJ. Cartilage and chondrocyte responses to mechanical loading in vitro. In: Helminen HJ, ed. Joint loading. Bristol: Wright, 1987: 112-25.
    • (1987) Joint Loading , pp. 112-125
    • Van Kampen, G.P.J.1    Van Der Stadt, R.J.2
  • 10
    • 0026484088 scopus 로고
    • Response of plasma membrane to applied hydrostatic pressure in chondrocytes and fibroblasts
    • Wright MO, Stockwell RA, Nuki G. Response of plasma membrane to applied hydrostatic pressure in chondrocytes and fibroblasts. Connect Tissue Res 1992; 28: 49-70.
    • (1992) Connect Tissue Res , vol.28 , pp. 49-70
    • Wright, M.O.1    Stockwell, R.A.2    Nuki, G.3
  • 11
    • 79957574728 scopus 로고
    • Calcium transport and the properties of a calcium-activated potassium channel in red cell membranes
    • Bronner F, Kleinzeller A, eds. New York; Academic Press
    • Lew VL, Ferreira HG. Calcium transport and the properties of a calcium-activated potassium channel in red cell membranes. In: Bronner F, Kleinzeller A, eds. Current topics in membranes and transport. vol 10. New York; Academic Press. 1978: 217-77.
    • (1978) Current Topics in Membranes and Transport , vol.10 , pp. 217-277
    • Lew, V.L.1    Ferreira, H.G.2
  • 12
    • 0015443477 scopus 로고
    • Differentiation of the transmembrane Na and Ca channels in mammalian cardiac fibres by the use of specific inhibitors
    • Komlhardt M, Bauer B, Krause M, Fleckenstein A. Differentiation of the transmembrane Na and Ca channels in mammalian cardiac fibres by the use of specific inhibitors. Pflugers Arch 1972; 335: 309-22
    • (1972) Pflugers Arch , vol.335 , pp. 309-322
    • Komlhardt, M.1    Bauer, B.2    Krause, M.3    Fleckenstein, A.4
  • 13
    • 0000784563 scopus 로고
    • Drug action and cellular calcium regulation
    • Janis RA, Silver PJ, Triggle DJ. Drug action and cellular calcium regulation. Adv Drug Res 1987; 16: 309-591.
    • (1987) Adv Drug Res , vol.16 , pp. 309-591
    • Janis, R.A.1    Silver, P.J.2    Triggle, D.J.3
  • 14
    • 0026523705 scopus 로고
    • Mechanotransduction
    • French AS, Mechanotransduction. Ann Rev Physiol 1992; 54: 135-52.
    • (1992) Ann Rev Physiol , vol.54 , pp. 135-152
    • French, A.S.1
  • 15
    • 0024996648 scopus 로고
    • Multiple forms of mechanosensitive ion channels in osteoblast-like cells
    • Davidson RM, Tatakis DW, Auerbach AL. Multiple forms of mechanosensitive ion channels in osteoblast-like cells. Pflugers Arch 1990; 416: 646-51.
    • (1990) Pflugers Arch , vol.416 , pp. 646-651
    • Davidson, R.M.1    Tatakis, D.W.2    Auerbach, A.L.3
  • 16
    • 0024364960 scopus 로고
    • 2+ conducting channels in an osteoclast-like line (UMR 106)
    • 2+ conducting channels in an osteoclast-like line (UMR 106). FEBS Lett 1989; 251: 17-21.
    • (1989) FEBS Lett , vol.251 , pp. 17-21
    • Duncan, R.1    Misler, S.2
  • 17
    • 0023904261 scopus 로고
    • Stretch-activated cation channels in human fibroblasts
    • Stockbridge LL, French AS. Stretch-activated cation channels in human fibroblasts. Biophys J 1988; 54: 187-90.
    • (1988) Biophys J , vol.54 , pp. 187-190
    • Stockbridge, L.L.1    French, A.S.2
  • 18
    • 0020466543 scopus 로고
    • Aggregated chondrocytes as a model system to study cartilage metabolism
    • van Kampen GPJ, Veldhuijzen JP. Aggregated chondrocytes as a model system to study cartilage metabolism. Exp Cell Res 1982; 140: 440-3.
    • (1982) Exp Cell Res , vol.140 , pp. 440-443
    • Van Kampen, G.P.J.1    Veldhuijzen, J.P.2
  • 19
    • 0026453353 scopus 로고
    • Cellular responses to human chondrocytes: Absence of allogeneic responses in the presence of HLA-DR and ICAM-1
    • Jobanputra P, Corrigall V, Kingsley G, Panayi G. Cellular responses to human chondrocytes: absence of allogeneic responses in the presence of HLA-DR and ICAM-1. Clin Exp Immunol 1992; 90: 336-44
    • (1992) Clin Exp Immunol , vol.90 , pp. 336-344
    • Jobanputra, P.1    Corrigall, V.2    Kingsley, G.3    Panayi, G.4
  • 20
    • 0013079380 scopus 로고
    • Response of single motor neurones to direct stimulation in the toad's spinal cord
    • Araki T, Otani T. Response of single motor neurones to direct stimulation in the toad's spinal cord. J Neurophysiol 1955; 18: 472-85.
    • (1955) J Neurophysiol , vol.18 , pp. 472-485
    • Araki, T.1    Otani, T.2
  • 21
    • 0015734457 scopus 로고
    • Contact inhibition of division: Involvement of the electrical transmembrane potential
    • Cone CD, Tongier M. Contact inhibition of division: involvement of the electrical transmembrane potential. J Cell Physiol 1973; 82: 373-86.
    • (1973) J Cell Physiol , vol.82 , pp. 373-386
    • Cone, C.D.1    Tongier, M.2
  • 22
    • 0023683014 scopus 로고
    • Amiloride blocks the mechano-electrical transduction channel of hair cells in the chick
    • Jorgensen F, Ohmori H. Amiloride blocks the mechano-electrical transduction channel of hair cells in the chick. J Physiol 1988; 403: 577-88.
    • (1988) J Physiol , vol.403 , pp. 577-588
    • Jorgensen, F.1    Ohmori, H.2
  • 23
    • 0026702525 scopus 로고
    • Amiloride: A molecular probe for mechano-sensitive channels
    • Hamill OP, Lane JW, McBride DW. Amiloride: a molecular probe for mechano-sensitive channels. Trends Pharmacol Sci 1992; 13: 373-6.
    • (1992) Trends Pharmacol Sci , vol.13 , pp. 373-376
    • Hamill, O.P.1    Lane, J.W.2    McBride, D.W.3
  • 24
    • 0024539514 scopus 로고
    • Block of stretch-activated ion channels in Xenopus oocytes by gadolinium and calcium ions
    • Washington DC
    • Yang XC, Sachs F, Block of stretch-activated ion channels in Xenopus oocytes by gadolinium and calcium ions. Science (Washington DC) 1989; 243: 1068-71.
    • (1989) Science , vol.243 , pp. 1068-1071
    • Yang, X.C.1    Sachs, F.2
  • 25
    • 0023162172 scopus 로고
    • Characterization of two types of calcium channels in mouse neuroblastoma cells
    • London
    • Narahashi T, Tsunoo A, Yoshii M. Characterization of two types of calcium channels in mouse neuroblastoma cells. J Physiol (London) 1987; 383: 231-49.
    • (1987) J Physiol , vol.383 , pp. 231-249
    • Narahashi, T.1    Tsunoo, A.2    Yoshii, M.3
  • 26
    • 85035156319 scopus 로고
    • Block of calcium channels by enkephalin and somatostatin in neuroblastoma-glioma hybrid NG108-15 cells
    • Tsunoo A, Yoshii M, Narahashi T. Block of calcium channels by enkephalin and somatostatin in neuroblastoma-glioma hybrid NG108-15 cells. Proc Natl Acad Sci 1990; 265: 11083-90.
    • (1990) Proc Natl Acad Sci , vol.265 , pp. 11083-11090
    • Tsunoo, A.1    Yoshii, M.2    Narahashi, T.3
  • 27
    • 0022994018 scopus 로고
    • + channels of small conductance in cultured rat skeletal muscle
    • + channels of small conductance in cultured rat skeletal muscle. Nature (London) 1986; 323: 718-20.
    • (1986) Nature (London) , vol.323 , pp. 718-720
    • Blatz, A.L.1    Magleby, K.L.2
  • 28
    • 9044253257 scopus 로고
    • Purification and characterisation of a unique, potent, peptidyl probe for the high conductance calcium-activated potassium channel from the venom of the scorpion Buthus tamulus
    • Galvez A, Gimenez-Gallego G, Reuben JP, et al. Purification and characterisation of a unique, potent, peptidyl probe for the high conductance calcium-activated potassium channel from the venom of the scorpion Buthus tamulus. J Biol Chem 1986; 83: 9832-6.
    • (1986) J Biol Chem , vol.83 , pp. 9832-9836
    • Galvez, A.1    Gimenez-Gallego, G.2    Reuben, J.P.3
  • 30
    • 0023635053 scopus 로고
    • Charybdotoxin selectively blocks small Ca-activated K channels in aplysia neurons
    • Hermann A, Erxleben C. Charybdotoxin selectively blocks small Ca-activated K channels in aplysia neurons. J Gen Physiol 1987; 90: 27-47.
    • (1987) J Gen Physiol , vol.90 , pp. 27-47
    • Hermann, A.1    Erxleben, C.2
  • 31
    • 0020136308 scopus 로고
    • A simple method for the accurate determination of free [Ca] in Ca-EGTA solutions
    • Bers DM. A simple method for the accurate determination of free [Ca] in Ca-EGTA solutions. Am J Physiol 1982; 242: C404-8.
    • (1982) Am J Physiol , vol.242
    • Bers, D.M.1
  • 32
    • 0022542171 scopus 로고
    • Comparison of the effects of BRL 34915 and verapamil on electrical and mechanical activity in the rat portal vein
    • Hamilton TC, Weir SW, Weston AH. Comparison of the effects of BRL 34915 and verapamil on electrical and mechanical activity in the rat portal vein. Br J Pharmacol 1986; 88: 103-11.
    • (1986) Br J Pharmacol , vol.88 , pp. 103-111
    • Hamilton, T.C.1    Weir, S.W.2    Weston, A.H.3
  • 34
    • 0025193998 scopus 로고
    • 2+-ATPase inhibitor, thapsigargin
    • 2+-ATPase inhibitor, thapsigargin. Agents Actions 1990; 29: 8-15.
    • (1990) Agents Actions , vol.29 , pp. 8-15
    • Thastrup, O.1
  • 36
    • 0026050850 scopus 로고
    • Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps
    • Lytton J, Westlin M, Hanley MR. Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps. J Biol Chem 1991; 266: 17067-71
    • (1991) J Biol Chem , vol.266 , pp. 17067-17071
    • Lytton, J.1    Westlin, M.2    Hanley, M.R.3
  • 37
    • 0024513869 scopus 로고
    • Identification of a novel inflammatory stimulant of chondrocytes. Early events in cell activation by bradykinin receptors on pig articular chondrocytes
    • Benton HP, Jackson TR, Hawley MR. Identification of a novel inflammatory stimulant of chondrocytes. Early events in cell activation by bradykinin receptors on pig articular chondrocytes. Biochem J 1989; 258: 861-7.
    • (1989) Biochem J , vol.258 , pp. 861-867
    • Benton, H.P.1    Jackson, T.R.2    Hawley, M.R.3
  • 38
    • 0000193782 scopus 로고
    • Ionic currents underlying in the giant axon of the squid
    • Hodgkin AL, Huxley AF, Katz B. Ionic currents underlying in the giant axon of the squid. Arch Sci Physiol 1949; 3: 129-50.
    • (1949) Arch Sci Physiol , vol.3 , pp. 129-150
    • Hodgkin, A.L.1    Huxley, A.F.2    Katz, B.3
  • 39
    • 0016205319 scopus 로고
    • The membrane potential of fibroblasts in different environments
    • Bard J, Wright MO. The membrane potential of fibroblasts in different environments. J Cell Physiol 1974; 84 141-6.
    • (1974) J Cell Physiol , vol.84 , pp. 141-146
    • Bard, J.1    Wright, M.O.2
  • 40
    • 0015839473 scopus 로고
    • Chondrocytes grown under mass monolayer conditions become dedifferentiated or fibroblast like
    • Sokoloff L, Malamud CJ, Srivastawa VML, Morgan WD, Chondrocytes grown under mass monolayer conditions become dedifferentiated or fibroblast like. Fed Proc Fed Am Soc Exp Biol 1973; 32: 1499-502.
    • (1973) Fed Proc Fed Am Soc Exp Biol , vol.32 , pp. 1499-1502
    • Sokoloff, L.1    Malamud, C.J.2    Srivastawa, V.M.L.3    Morgan, W.D.4
  • 41
    • 0000578058 scopus 로고
    • The loss of phenotypic traits by differentiated cells in vitro. I. Dedifferentiation of cartilage cells
    • Holtzer H, Abbot J, Lash J, Holtzer S. The loss of phenotypic traits by differentiated cells in vitro. I. Dedifferentiation of cartilage cells. Proc Natl Acad Sci 1960; 46: 1533-42.
    • (1960) Proc Natl Acad Sci , vol.46 , pp. 1533-1542
    • Holtzer, H.1    Abbot, J.2    Lash, J.3    Holtzer, S.4
  • 42
    • 0018221370 scopus 로고
    • Independent regulation of collagen types by chondrocytes during the loss of differentiated function in culture
    • Benya PD, Padilla SR, Nimni ME. Independent regulation of collagen types by chondrocytes during the loss of differentiated function in culture. Cell 1978; 15: 1313-21.
    • (1978) Cell , vol.15 , pp. 1313-1321
    • Benya, P.D.1    Padilla, S.R.2    Nimni, M.E.3
  • 46
    • 0001400914 scopus 로고
    • Physical modifiers of cartilage metabolism
    • Kuettner KE, Schleyerbach R, Peyron JG, Hascall VC, eds. New York: Raven Press
    • Urban J, Hall A. Physical modifiers of cartilage metabolism. In: Kuettner KE, Schleyerbach R, Peyron JG, Hascall VC, eds. Articular cartilage and osteoarthritis. New York: Raven Press, 1992: 393-406.
    • (1992) Articular Cartilage and Osteoarthritis , pp. 393-406
    • Urban, J.1    Hall, A.2
  • 47
    • 0027321110 scopus 로고
    • Effects of cyclic hydrostatic pressure on proteoglycan synthesis in cultured chondrocytes and articular cartilage expiants
    • Parkkinen JJ, Ikonen J, Lammi MJ, Laakkonen J, Tammi M, Helminen HJ. Effects of cyclic hydrostatic pressure on proteoglycan synthesis in cultured chondrocytes and articular cartilage expiants. Arch Biochem Biophys 1993; 300: 458-65.
    • (1993) Arch Biochem Biophys , vol.300 , pp. 458-465
    • Parkkinen, J.J.1    Ikonen, J.2    Lammi, M.J.3    Laakkonen, J.4    Tammi, M.5    Helminen, H.J.6
  • 48
    • 0019053362 scopus 로고
    • Changes in the deformational behaviour of human hip cartilage with age
    • Armstrong CG, Bahrani AS, Gardner DL. Changes in the deformational behaviour of human hip cartilage with age. J Biomech Eng 1980; 102: 214-20.
    • (1980) J Biomech Eng , vol.102 , pp. 214-220
    • Armstrong, C.G.1    Bahrani, A.S.2    Gardner, D.L.3
  • 49
    • 0018948011 scopus 로고
    • A study of the structural response of wet hyaline cartilage to various loading stresses
    • Broom ND, Myers DB. A study of the structural response of wet hyaline cartilage to various loading stresses. Connect Tissue Res 1980; 7: 227-37.
    • (1980) Connect Tissue Res , vol.7 , pp. 227-237
    • Broom, N.D.1    Myers, D.B.2
  • 50
    • 0017732532 scopus 로고
    • Survival of articular cartilage after controlled impact
    • Repo RU, Finlay JB. Survival of articular cartilage after controlled impact. J Bone Jt Surg 1977; 59: 1068-76.
    • (1977) J Bone Jt Surg , vol.59 , pp. 1068-1076
    • Repo, R.U.1    Finlay, J.B.2
  • 51
    • 0021352423 scopus 로고
    • In vitro response of chondrocytes to mechanical loading. The effect of short-term mechanical tension
    • De Witt M, Handley L, Oakes B, Lowther D. In vitro response of chondrocytes to mechanical loading. The effect of short-term mechanical tension. Connect Tissue Res 1984; 11: 97-109
    • (1984) Connect Tissue Res , vol.11 , pp. 97-109
    • De Witt, M.1    Handley, L.2    Oakes, B.3    Lowther, D.4
  • 52
    • 0026928502 scopus 로고
    • Local stimulation of proteoglycan synthesis in articular cartilage explants by dynamic compression in vitro
    • Parkkinen JJ, Lammi MJ, Helminen HJ, Tammi M. Local stimulation of proteoglycan synthesis in articular cartilage explants by dynamic compression in vitro. J Orthop Res 1992; 10: 610-20.
    • (1992) J Orthop Res , vol.10 , pp. 610-620
    • Parkkinen, J.J.1    Lammi, M.J.2    Helminen, H.J.3    Tammi, M.4
  • 53
    • 0024991276 scopus 로고
    • Gadolinium blocks low and high threshold calcium currents in pituitary cells
    • Biagi BA, Enyeart JJ. Gadolinium blocks low and high threshold calcium currents in pituitary cells. Am J Physiol 1990; 159: C515-20.
    • (1990) Am J Physiol , vol.159
    • Biagi, B.A.1    Enyeart, J.J.2
  • 54
    • 0026589784 scopus 로고
    • Stretch-activated single-channel and whole cell currents in vascular smooth muscle cells
    • Davis MJ, Danovitz JA, Hood JD, Stretch-activated single-channel and whole cell currents in vascular smooth muscle cells. Am J Physiol 1992; 262: C1083-8.
    • (1992) Am J Physiol , vol.262
    • Davis, M.J.1    Danovitz, J.A.2    Hood, J.D.3
  • 55
    • 0028211303 scopus 로고
    • The stretch-activated ion channel blocker gadolinium also blocks L-type calcium channels in isolated ventricular myocytes of the guinea pig
    • Lacampagne AL, Gannier F, Argibay J, Garnier D, Le Grennec J-Y. The stretch-activated ion channel blocker gadolinium also blocks L-type calcium channels in isolated ventricular myocytes of the guinea pig. Biochim Biophys Acta 1994; 1191: 205-8.
    • (1994) Biochim Biophys Acta , vol.1191 , pp. 205-208
    • Lacampagne, A.L.1    Gannier, F.2    Argibay, J.3    Garnier, D.4    Le Grennec, J.-Y.5
  • 57
    • 0023807201 scopus 로고
    • Amiloride and its analogs as tools in the study of ion transport
    • Kleyman TR, Cragoe EJ. Amiloride and its analogs as tools in the study of ion transport. J Membr Biol 1988; 105: 1-21.
    • (1988) J Membr Biol , vol.105 , pp. 1-21
    • Kleyman, T.R.1    Cragoe, E.J.2
  • 58
    • 0027521065 scopus 로고
    • Mechanical stretch rapidly activates multiple signal transduction pathways in cardiac myocytes: Potential involvement of an autocrine-paracrine mechanism
    • Sadoshima JI, Izumo S. Mechanical stretch rapidly activates multiple signal transduction pathways in cardiac myocytes: potential involvement of an autocrine-paracrine mechanism. EMBO J 1993; 12: 1681-92.
    • (1993) EMBO J , vol.12 , pp. 1681-1692
    • Sadoshima, J.I.1    Izumo, S.2
  • 61
    • 0028062112 scopus 로고
    • The chondrocyte: A cell under pressure
    • Urban JPG. The chondrocyte: a cell under pressure. Br J Rheumatol 1994; 33: 901-8
    • (1994) Br J Rheumatol , vol.33 , pp. 901-908
    • Urban, J.P.G.1
  • 62
    • 0001958494 scopus 로고
    • Structure and function of the chondrocyte under mechanical stress
    • Helminen HJ, ed. Bristol: Wright
    • Stockwell RA. Structure and function of the chondrocyte under mechanical stress. In: Helminen HJ, ed. Joint loading, Bristol: Wright, 1987: 126-48.
    • (1987) Joint Loading , pp. 126-148
    • Stockwell, R.A.1
  • 63
    • 0022897313 scopus 로고
    • Effects of mechanical and osmotic pressure on the rate of glycosaminoglycan synthesis in the human adult femoral head
    • Schneiderman R, Keret D, Maroudas A. Effects of mechanical and osmotic pressure on the rate of glycosaminoglycan synthesis in the human adult femoral head. J Orthop Res 1986; 4: 393-408.
    • (1986) J Orthop Res , vol.4 , pp. 393-408
    • Schneiderman, R.1    Keret, D.2    Maroudas, A.3
  • 64
    • 0009513348 scopus 로고
    • The correlation between changes in intracellular pH and changes in matrix synthesis rates in chondrocytes
    • Wilkins R, Hall AC, Urban JPG. The correlation between changes in intracellular pH and changes in matrix synthesis rates in chondrocytes. Trans Am Orthop Res Soc 1992; 17: 182.
    • (1992) Trans Am Orthop Res Soc , vol.17 , pp. 182
    • Wilkins, R.1    Hall, A.C.2    Urban, J.P.G.3
  • 65
    • 0026245524 scopus 로고
    • Integrins as mechanochemical transducers
    • Ingber D. Integrins as mechanochemical transducers. Curr Opin Cell Biol 1991; 3: 841-8.
    • (1991) Curr Opin Cell Biol , vol.3 , pp. 841-848
    • Ingber, D.1
  • 66
    • 0028987936 scopus 로고
    • Integrins and signal transduction pathways: The road taken
    • Washington DC
    • Clark EA, Brugge JS. Integrins and signal transduction pathways: the road taken. Science (Washington DC) 1995; 268: 233-9.
    • (1995) Science , vol.268 , pp. 233-239
    • Clark, E.A.1    Brugge, J.S.2
  • 67
    • 0026668794 scopus 로고
    • Roles of mechano-sensitive ion channels, cytoskeleton, and contractile activity in stretch-induced immediate-early gene expression and hypertrophy of cardiac myocytes
    • Sadoshima JI, Takahashi T, Jahn L, Izumo S. Roles of mechano-sensitive ion channels, cytoskeleton, and contractile activity in stretch-induced immediate-early gene expression and hypertrophy of cardiac myocytes. Proc Natl Acad Sci USA 1992; 89: 9905-9.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 9905-9909
    • Sadoshima, J.I.1    Takahashi, T.2    Jahn, L.3    Izumo, S.4


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