Vitamin C induces apoptosis in AGS cells by down-regulation of 14-3-3σ via a mitochondrial dependent pathway

Food Chemistry

Volumn 135, Issue 3, 2012, Pages 1920-1928

  Nagappan, Arulkumar ^a   Park, Kwang Il ^a   Park, Hyeon Soo ^a   Kim, Jin A ^a   Hong, Gyeong Eun ^a   Kang, Sang Rim ^b   Lee, Do Hoon ^a   Kim, Eun Hee ^c   Lee, Won Sup ^a   Won, Chung Kil ^a   Kim, Gon Sup ^a  

^a Gyeongsang National University   (South Korea)

^b Kyonggi University   (South Korea)

^c International University of Korea   (South Korea)

Author keywords

14 3 3 ; AGS cells; Apoptosis; Gastric cancer; Vitamin C

Indexed keywords

ANTICANCER ACTIVITIES; ANTIOXIDANT ACTIVITIES; ASCORBIC ACIDS; CANCER CELL GROWTH; CELLULAR MECHANISMS; CYTOTOXIC EFFECTS; DOSE-DEPENDENT MANNER; DOWN-REGULATION; ESSENTIAL COMPONENT; FLOW CYTOMETRY ANALYSIS; GASTRIC CANCER CELL LINES; GASTRIC CANCERS; HUMAN CANCER CELLS; IN-VITRO; LIVING CELL; PROTEIN LEVEL; THERAPEUTIC AGENTS; VITAMIN C; WOUND HEALING;

CELL CULTURE; CELL PROLIFERATION; CYTOTOXICITY; DISEASES; KETONES; ORGANIC ACIDS; PHOSPHORYLATION; VITAMINS;

CELL DEATH;

ASCORBIC ACID; CASPASE 3; CASPASE 6; CASPASE 9; FLUORESCEIN ISOTHIOCYANATE; LIPOCORTIN 5; PROTEIN 14 3 3; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL XL;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL AGS; CANCER CELL CULTURE; CELL CYCLE PHASE; CELL LINE; CELL PROLIFERATION; CYTOTOXICITY; DOWN REGULATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MITOCHONDRION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STOMACH CANCER; WOUND HEALING;

14-3-3 PROTEINS; APOPTOSIS; ASCORBIC ACID; BCL-2-ASSOCIATED X PROTEIN; CELL LINE, TUMOR; CELL PROLIFERATION; DOWN-REGULATION; HUMANS; MITOCHONDRIA; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION;

EID: 84865758192     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2012.06.050     Document Type: Article

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