3,6'-Dithiothalidomide, a new TNF-α synthesis inhibitor, attenuates the effect of Aβ1-42 intracerebroventricular injection on hippocampal neurogenesis and memory deficit

Journal of Neurochemistry

Volumn 122, Issue 6, 2012, Pages 1181-1192

  Russo, Isabella ^a,b   Caracciolo, Luca ^a   Tweedie, David ^a   Choi, Sang Ho ^a   Greig, Nigel H ^a   Barlati, Sergio ^b   Bosetti, Francesca ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b UNIVERSITY OF BRESCIA   (Italy)

Author keywords

3,6' dithiothalidomide; A 1 42 peptide; Alzheimer's disease; neurogenesis; neuroinflammation; TNF

Indexed keywords

3,6' DITHIOTHALIDOMIDE; BROXURIDINE; TUMOR NECROSIS FACTOR ALPHA INHIBITOR; UNCLASSIFIED DRUG;

AMNESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL COUNT; CELL PROLIFERATION; CELL STRUCTURE; CELL SURVIVAL; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG RESEARCH; DRUG STRUCTURE; HIPPOCAMPUS; MALE; MENTAL TASK; MICROGLIA; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NERVOUS SYSTEM INFLAMMATION; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; TASK PERFORMANCE;

AMYLOID BETA-PEPTIDES; ANIMALS; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; INJECTIONS, INTRAVENTRICULAR; MALE; MEMORY DISORDERS; MICE; MICE, INBRED C57BL; NEUROGENESIS; PEPTIDE FRAGMENTS; THALIDOMIDE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84865748485     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2012.07846.x     Document Type: Article

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