BBS-induced ciliary defect enhances adipogenesis, causing paradoxical higher-insulin sensitivity, glucose usage, and decreased inflammatory response

Cell Metabolism

Volumn 16, Issue 3, 2012, Pages 363-377

  Marion, Vincent ^a   Mockel, Anaïs ^a   De Melo, Charlie ^a   Obringer, Cathy ^a   Claussmann, Aurélie ^a   Simon, Alban ^b   Messaddeq, Nadia ^a   Durand, Myriam ^c   Dupuis, Luc ^d   Loeffler, Jean Philippe ^d   King, Peter ^e   Mutter Schmidt, Catherine ^b   Petrovsky, Nikolai ^f   Stoetzel, Corinne ^a   Dollfus, Hélène ^a,c  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b Université de Strasbourg   (France)

^c UNIVERSITY HOSPITAL OF STRASBOURG   (France)

^d INSERM   (France)

^e QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^f FLINDERS UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ADIPONECTIN; ARGINASE 1; CD68 ANTIGEN; CIGLITAZONE; CYCLOOXYGENASE 1; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FAS ANTIGEN; GLUCOSE; GLUCOSE TRANSPORTER 4; INDUCIBLE NITRIC OXIDE SYNTHASE; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; INTERLEUKIN 10; INTERLEUKIN 13; LEPTIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN KINASE B; RESERPINE; RESISTIN; TRIACYLGLYCEROL; TROGLITAZONE; TUMOR NECROSIS FACTOR ALPHA;

ADIPOGENESIS; ADIPOSE TISSUE; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BARDET BIEDL SYNDROME; BBS 12 GENE; BODY MASS; BODY WEIGHT; CELL DIFFERENTIATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOLOGY; EUKARYOTIC FLAGELLUM; FEMALE; FOOD INTAKE; GENE; GENE CONTROL; GENE EXPRESSION; GENE INACTIVATION; GLUCOSE ABSORPTION; GLUCOSE TOLERANCE; GLUCOSE UTILIZATION; HUMAN; HUMAN TISSUE; IN VITRO STUDY; INFLAMMATION; INSULIN SENSITIVITY; LIPID METABOLISM; MALE; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; OBESITY; ORAL GLUCOSE TOLERANCE TEST; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRIACYLGLYCEROL BLOOD LEVEL;

ADIPOCYTES; ADIPOGENESIS; ANIMALS; BARDET-BIEDL SYNDROME; CHAPERONINS; HUMANS; INSULIN RESISTANCE; MICE; MICE, KNOCKOUT; OBESITY; SIGNAL TRANSDUCTION;

EID: 84865711698     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2012.08.005     Document Type: Article

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