Bacillus-derived poly-γ-glutamic acid reciprocally regulates the differentiation of T helper 17 and regulatory T cells and attenuates experimental autoimmune encephalomyelitis

Clinical and Experimental Immunology

Volumn 170, Issue 1, 2012, Pages 66-76

  Lee, K ^a   Hwang, S ^a   Paik, D J ^a   Kim, W K ^a   Kim, J M ^a   Youn, J ^a  

^a Hanyang University   (South Korea)

Author keywords

Autoimmune disease; Experimental autoimmune encephalomyelitis; Poly glutamic acid; Regulatory T cells; Th17 cells

Indexed keywords

IMMUNOLOGIC AGENT; INTERFERON REGULATORY FACTOR 4; INTERLEUKIN 17; MYELOID DIFFERENTIATION FACTOR 88; POLY GAMMA GLUTAMIC ACID; RETINOID RELATED ORPHAN RECEPTOR GAMMA; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BACILLUS; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; FEMALE; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; TH17 CELL;

ANIMALS; AUTOIMMUNE DISEASES; AUTOIMMUNITY; BACILLUS; CELL DIFFERENTIATION; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; FLOW CYTOMETRY; FORKHEAD TRANSCRIPTION FACTORS; INTERLEUKIN-17; INTERLEUKIN-6; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, TRANSGENIC; MYELOID DIFFERENTIATION FACTOR 88; POLYGLUTAMIC ACID; RECEPTORS, RETINOIC ACID; STAT3 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; T-LYMPHOCYTES, REGULATORY; TH17 CELLS; TOLL-LIKE RECEPTOR 3; TOLL-LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA;

EID: 84865634958     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2012.04637.x     Document Type: Article

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