메뉴 건너뛰기




Volumn 12, Issue 4, 2012, Pages 321-331

Does early feeding promote development of oral tolerance?

Author keywords

Allergen avoidance; Allergenic foods; Allergy prevention; Birth cohort; Complementary feeding; Early feeding; Food sensitization; Infant nutrition; Oral tolerance

Indexed keywords

FOOD ALLERGEN;

EID: 84865575296     PISSN: 15297322     EISSN: 15346315     Source Type: Journal    
DOI: 10.1007/s11882-012-0271-6     Document Type: Article
Times cited : (18)

References (65)
  • 1
    • 34447278870 scopus 로고    scopus 로고
    • Paediatric food allergy trends in a community-based specialist allergy practice, 1995-2006
    • Mullins RJ. Paediatric food allergy trends in a community-based specialist allergy practice, 1995-2006.Med J Aust. 2007;186:618-21. (Pubitemid 47044681)
    • (2007) Medical Journal of Australia , vol.186 , Issue.12 , pp. 618-621
    • Mullins, R.J.1
  • 2
    • 79952286242 scopus 로고    scopus 로고
    • Prevalence of challenge-proven igemediated food allergy using population-based sampling and predetermined challenge criteria in infants
    • e2
    • Osborne NJ, Koplin JJ, Martin PE, Gurrin LC, Lowe AJ, Matheson MC, et al. Prevalence of challenge-proven IgEmediated food allergy using population-based sampling and predetermined challenge criteria in infants. J Allergy Clin Immunol. 2011;127:668-76 e2.
    • (2011) J Allergy Clin Immunol. , vol.127 , pp. 668-76
    • Osborne, N.J.1    Koplin, J.J.2    Martin, P.E.3    Gurrin, L.C.4    Lowe, A.J.5    Matheson, M.C.6
  • 4
    • 77958135598 scopus 로고    scopus 로고
    • Partial protein-hydrolyzed infant formula decreased food sensitization but not allergic diseases in a prospective birth cohort study
    • Kuo HC, Liu CA, Ou CY, Hsu TY, Wang CL, Huang HC, et al. Partial protein-hydrolyzed infant formula decreased food sensitization but not allergic diseases in a prospective birth cohort study. Int Arch Allergy Immunol. 2011;154:310-7.
    • (2011) Int Arch Allergy Immunol , vol.154 , pp. 310-317
    • Kuo, H.C.1    Liu, C.A.2    Ou, C.Y.3    Hsu, T.Y.4    Wang, C.L.5    Huang, H.C.6
  • 5
    • 79960999839 scopus 로고    scopus 로고
    • Effect of a partially hydrolyzed whey infant formula at weaning on risk of allergic disease in high-risk children: A randomized controlled trial
    • e4
    • Lowe AJ, Hosking CS, Bennett CM, Allen KJ, Axelrad C, Carlin JB, et al. Effect of a partially hydrolyzed whey infant formula at weaning on risk of allergic disease in high-risk children: a randomized controlled trial. J Allergy Clin Immunol. 2011; 128:360-5 e4.
    • (2011) J Allergy Clin Immunol. , vol.128 , pp. 360-365
    • Lowe, A.J.1    Hosking, C.S.2    Bennett, C.M.3    Allen, K.J.4    Axelrad, C.5    Carlin, J.B.6
  • 6
    • 39049174690 scopus 로고    scopus 로고
    • Soy formula for prevention of allergy and food intolerance in infants
    • Osborn DA, Sinn J. Soy formula for prevention of allergy and food intolerance in infants. Cochrane Database Syst Rev 2006: CD003741.
    • (2006) Cochrane Database Syst Rev
    • Osborn, D.A.1    Sinn, J.2
  • 7
    • 84865597186 scopus 로고    scopus 로고
    • Systematic review of formulas containing hydrolysed protein for prevention of allergy and food intolerance in infants
    • Osborn DA, Sinn J. Systematic review of formulas containing hydrolysed protein for prevention of allergy and food intolerance in infants. J Paediatr Child Health. 2012;48 Suppl 1:26.
    • (2012) J Paediatr Child Health , vol.48 , Issue.SUPPL. 1 , pp. 26
    • Osborn, D.A.1    Sinn, J.2
  • 8
    • 0030485055 scopus 로고    scopus 로고
    • Prevention of allergic disease. Exposure to food allergens and dietetic intervention
    • Halken S, Host A. Prevention of allergic disease. Exposure to food allergens and dietetic intervention. Pediatr Allergy Immunol. 1996;7:102-7. (Pubitemid 27081296)
    • (1996) Pediatric Allergy and Immunology, Supplement , vol.7 , Issue.9 , pp. 102-107
    • Halken, S.1    Host, A.2
  • 10
    • 0027192189 scopus 로고
    • Relation between early introduction of solid food to infants and their weight and illnesses during the first two years of life
    • Forsyth JS, Ogston SA, Clark A, Florey CD, Howie PW. Relation between early introduction of solid food to infants and their weight and illnesses during the first two years of life. BMJ. 1993; 306:1572-6. (Pubitemid 23164898)
    • (1993) British Medical Journal , vol.306 , Issue.6892 , pp. 1572-1576
    • Forsyth, J.S.1    Ogston, S.A.2    Clark, A.3    Du Florey, V.C.4    Howie, P.W.5
  • 11
    • 0020570122 scopus 로고
    • Prophylaxis of atopic disease by six months' total solid food elimination. Evaluation of 135 exclusively breast-fed infants of atopic families
    • Kajosaari M, Saarinen UM Prophylaxis of atopic disease by six months' total solid food elimination. Evaluation of 135 exclusively breast-fed infants of atopic families. Acta Paediatr Scand. 1983;72:411-4. (Pubitemid 13088021)
    • (1983) Acta Paediatrica Scandinavica , vol.72 , Issue.3 , pp. 411-414
    • Kajosaari, M.1    Saarinen, U.M.2
  • 14
    • 34247394269 scopus 로고    scopus 로고
    • The association between infant feeding practices and subsequent atopy among children with a family history of asthma
    • DOI 10.1111/j.1365-2222.2007.02696.x
    • Mihrshahi S, Ampon R, Webb K, Almqvist C, Kemp AS, Hector D, et al. The association between infant feeding practices and subsequent atopy among children with a family history of asthma. Clin Exp Allergy. 2007;37:671-9. (Pubitemid 46643055)
    • (2007) Clinical and Experimental Allergy , vol.37 , Issue.5 , pp. 671-679
    • Mihrshahi, S.1    Ampon, R.2    Webb, K.3    Almqvist, C.4    Kemp, A.S.5    Hector, D.6    Marks, G.B.7
  • 15
    • 0026718118 scopus 로고
    • Effect of allergen avoidance on development of allergic disorders in infancy
    • Arshad SH, Matthews S, Gant C, Hide DW. Effect of allergen avoidance on development of allergic disorders in infancy. Lancet. 1992;339:1493-7.
    • (1992) Lancet , vol.339 , pp. 1493-1497
    • Arshad, S.H.1    Matthews, S.2    Gant, C.3    Hide, D..W.4
  • 17
    • 0033798678 scopus 로고    scopus 로고
    • Improved general health status in an unselected infant population following an allergen-reduced dietary intervention programme: The zuff-study-programme. Part ii: Infant growth and health status to age 6 months
    • Exl BM, Deland U, Secretin MC, Preysch U, Wall M, Shmerling DH. Improved general health status in an unselected infant population following an allergen-reduced dietary intervention programme: the ZUFF-STUDY-PROGRAMME. Part II: infant growth and health status to age 6 months. Eur J Nutr. 2000; 39:145-56.
    • (2000) Eur J Nutr. , vol.39 , pp. 145-156
    • Exl, B.M.1    Deland, U.2    Secretin, M.C.3    Preysch, U.4    Wall, M.5    Shmerling, D.H.6
  • 20
    • 0030037420 scopus 로고    scopus 로고
    • Effects of a dietary and environmental prevention programme on the incidence of allergic symptoms in high atopic risk infants: Three years' follow-up
    • Marini A, Agosti M, Motta G, Mosca F. Effects of a dietary and environmental prevention programme on the incidence of allergic symptoms in high atopic risk infants: three years' follow-up. Acta Paediatr Supp. 1996;414:1-21.
    • (1996) Acta Paediatr Supp , vol.414 , pp. 1-21
    • Marini, A.1    Agosti, M.2    Motta, G.3    Mosca, F.4
  • 21
    • 0034241552 scopus 로고    scopus 로고
    • Hypoallergenic infant formulas
    • American Academy of Pediatrics. Committee on nutrition
    • American Academy of Pediatrics. Committee on nutrition. Hypoallergenic infant formulas. Pediatrics. 2000;106:346-9.
    • (2000) Pediatrics. , vol.106 , pp. 346-349
  • 29
    • 38049043855 scopus 로고    scopus 로고
    • Effects of early nutritional interventions on the development of atopic disease in infants and children: The role of maternal dietary restriction, breastfeeding, timing of introduction of complementary foods and hydrolysed formulas
    • Greer FR, Sicherer SH, Burks AW. Effects of early nutritional interventions on the development of atopic disease in infants and children: the role of maternal dietary restriction, breastfeeding, timing of introduction of complementary foods and hydrolysed formulas. Pediatrics. 2008;121:183-91.
    • (2008) Pediatrics , vol.121 , pp. 183-191
    • Greer, F.R.1    Sicherer, S.H.2    Burks, A..W.3
  • 32
    • 78851470060 scopus 로고    scopus 로고
    • Infant feeding practices and physician diagnosed atopic dermatitis: A prospective cohort study in taiwan
    • This study of 18,773 Taiwan infants found no relationship the age of introduction of solids in relationship to the risk of eczema by 18 months of age: with no difference in the rate of disease if solid foods were introduced <4 months compared with 4-6 months or beyond 6 months In this cohort a history of allergic disease was found in 30.1% of parents and the majority (85.5%) of infants were introduced to solid food between 4 and 6 months of age. The prevalence of parent-reported, physician-diagnosed eczema ( 12.1%) was lower than in other recent population based studies
    • Chuang CH, Hsieh WS, Chen YC, Chang PJ, Hurng BS, Lin SJ, et al. Infant feeding practices and physician diagnosed atopic dermatitis: a prospective cohort study in Taiwan. Pediatr Allergy Immunol. 2011;22:43-9. This study of 18,773 Taiwan infants found no relationship the age of introduction of solids in relationship to the risk of eczema by 18 months of age: with no difference in the rate of disease if solid foods were introduced <4 months compared with 4-6 months or beyond 6 months. In this cohort a history of allergic disease was found in 30.1% of parents and the majority (85.5%) of infants were introduced to solid food between 4 and 6 months of age. The prevalence of parent-reported, physician-diagnosed eczema (12.1%) was lower than in other recent population based studies.
    • (2011) Pediatr Allergy Immunol , vol.22 , pp. 43-9
    • Chuang, C.H.1    Hsieh, W.S.2    Chen, Y.C.3    Chang, P.J.4    Hurng, B.S.5    Lin, S.J.6
  • 33
    • 79955641582 scopus 로고    scopus 로고
    • Early complementary feeding and risk of food sensitization in a birth cohort
    • e5 In this USA prospective, birth cohort ( n0594) early complementary food (<4 months) was not related to eczema by age 2 years in a setting where 397% of mothers reported infant exposure to complementary food by 4 months Early complementary food (<4 months) reduced the risk of peanut sensitization (peanut IgE ≥035 IU/mL adjusted OR 02 95% CI 01-n0594) early complementary food (<4 months) was not related to eczema by age 2 years in a setting where 397% of mothers reported infant exposure to complementary food by 4 months Early complementary food (<4 months) reduced t07 P 0 0007) and egg sensitisation (egg IgE ≥070 IU/mL adjusted OR 05 95% CI 03 0.022) among children with a parental history of allergy. There were high rates of sensitization to the major food allergens in this study, and a major limitation was that neither food challenges nor data on clinical food allergy were provided
    • Joseph CL, Ownby DR, Havstad SL, Woodcroft KJ, Wegienka G, MacKechnie H, et al. Early complementary feeding and risk of food sensitization in a birth cohort. J Allergy Clin Immunol. 2011;127:1203-10 e5. In this USA prospective, birth cohort (n0594) early complementary food (<4 months) was not related to eczema by age 2 years, in a setting where 39.7% of mothers reported infant exposure to complementary food by 4 months. Early complementary food (<4 months) reduced the risk of peanut sensitization (peanut IgE ≥0.35 IU/mL; adjusted OR 0.2, 95% CI, 0.1-0.7; P 0 0.007) and egg sensitisation (egg IgE ≥0.70 IU/mL; adjusted OR, 0.5, 95% CI, 0.3-0.9; P 0 0.022) among children with a parental history of allergy. There were high rates of sensitization to the major food allergens in this study, and a major limitation was that neither food challenges nor data on clinical food allergy were provided.
    • (2011) J Allergy Clin Immunol , vol.127 , pp. 1203-1210
    • Joseph, C.L.1    Ownby, D.R.2    Havstad, S.L.3    Woodcroft, K.J.4    Wegienka, G.5    MacKechnie, H.6
  • 34
    • 38049095529 scopus 로고    scopus 로고
    • Timing of solid food introduction in relation to eczema, asthma, allergic rhinitis, and food and inhalant sensitization at the age of 6 years: Results from the prospective birth cohort study lisa
    • Zutavern A, Brockow I, Schaaf B, von Berg A, Diez U, Borte M, et al. Timing of solid food introduction in relation to eczema, asthma, allergic rhinitis, and food and inhalant sensitization at the age of 6 years: results from the prospective birth cohort study LISA. Pediatrics. 2008;121:e44-52.
    • (2008) Pediatrics. , vol.121
    • Zutavern, A.1    Brockow, I.2    Schaaf, B.3    Von Berg, A.4    Diez, U.5    Borte, M.6
  • 35
    • 58349093506 scopus 로고    scopus 로고
    • Early introduction of fish decreases the risk of eczema in infants
    • In this Swedish (n04953) study 20.9% infants developed eczema by 1 year of age, but there was a significantly reduced risk in infants who were introduced to fish before 9 months of age. In this study 78.6% consumed lean fish (cod, haddock) and 18.3% consumed fatty fish (mainly salmon
    • Alm B, Aberg N, Erdes L, Mollborg P, Pettersson R, Norvenius SG, et al. Early introduction of fish decreases the risk of eczema in infants. Arch Dis Child. 2009;94:11-5. In this Swedish (n04953) study 20.9% infants developed eczema by 1 year of age, but there was a significantly reduced risk in infants who were introduced to fish before 9 months of age. In this study 78.6% consumed lean fish (cod, haddock) and 18.3% consumed fatty fish (mainly salmon
    • (2009) Arch Dis Child. , vol.94 , pp. 11-5
    • Alm, B.1    Aberg, N.2    Erdes, L.3    Mollborg, P.4    Pettersson, R.5    Norvenius, S.G.6
  • 36
    • 78349266055 scopus 로고    scopus 로고
    • Early fish introduction is associated with less eczema, but not sensitization, in infants
    • A smaller Swedish study (n0184) observed an eczema prevalence of 25% by 18 months of age. The prevalence increased 16% for every 2 months that introduction of fish was delayed. The median age of fish introduction for children who had not developed eczema was 8 months (IQR 6.0-11.0 months) compared to 11 months (IQR 80-130 months for those children who had develoed eczema but sensitization was not associated with the timing of fish introduction
    • Hesselmar B, Saalman R, Rudin A, Adlerberth I, Wold A. Early fish introduction is associated with less eczema, but not sensitization, in infants. Acta Paediatr. 2010;99:1861-7. A smaller Swedish study (n0184) observed an eczema prevalence of 25% by 18 months of age. The prevalence increased 16% for every 2 months that introduction of fish was delayed. The median age of fish introduction for children who had not developed eczema was 8 months (IQR 6.0-11.0 months) compared to 11 months (IQR 8.0-13.0 months) for those children who had developed eczema but sensitization was not associated with the timing of fish introduction.
    • (2010) Acta Paediatr. , vol.99 , pp. 1861-1867
    • Hesselmar, B.1    Saalman, R.2    Rudin, A.3    Adlerberth, I.4    Wold, A.5
  • 37
    • 48249100909 scopus 로고    scopus 로고
    • Age at first introduction of cow milk products and other food products in relation to infant atopic manifestations in the first 2 years of life: The koala birth cohort study
    • Snijders BE, Thijs C, van Ree R, van den Brandt PA. Age at first introduction of cow milk products and other food products in relation to infant atopic manifestations in the first 2 years of life: the KOALA Birth Cohort Study. Pediatrics. 2008;122:e115-22.
    • (2008) Pediatrics. , vol.122 , pp. 115-122
    • Snijders, B.E.1    Thijs, C.2    Van Ree, R.3    Van Den Brandt, P.A.4
  • 38
    • 75549090262 scopus 로고    scopus 로고
    • Early introduction of oats associated with decreased risk of persistent asthma and early introduction of fish with decreased risk of allergic rhinitis
    • These authors report that introduction of oats ≤5.5months of age was associated with a reduced risk of persistent asthma. Introduction of fish (≤8.5months of age) was associated with a decreased risk of allergic rhinitis at 5 years. Among the children participating in this cohort, 60% (77 /1293) developed persistent asthma and 144% (185 /1288) allergic rhinitis by the age of 5 years
    • Virtanen SM, Kaila M, Pekkanen J, Kenward MG, Uusitalo U, Pietinen P, et al. Early introduction of oats associated with decreased risk of persistent asthma and early introduction of fish with decreased risk of allergic rhinitis. Br J Nutr. 2010;103:266-73. These authors report that introduction of oats ≤5.5months of age was associated with a reduced risk of persistent asthma. Introduction of fish (≤8.5months of age) was associated with a decreased risk of allergic rhinitis at 5 years. Among the children participating in this cohort, 60% (77 /1293) developed persistent asthma and 144% (185 /1288) allergic rhinitis by the age of 5 years.
    • (2010) Br J Nutr , vol.103 , pp. 266-273
    • Virtanen, S.M.1    Kaila, M.2    Pekkanen, J.3    Kenward, M.G.4    Uusitalo, U.5    Pietinen, P.6
  • 39
    • 74049161266 scopus 로고    scopus 로고
    • Age at the introduction of solid foods during the first year and allergic sensitization at age 5 years
    • In this study, delayed introduction of specific foods, in particular potatoes (>4 months), oats (>5 months), rye (>7 months), wheat (>6 months), meat (>5.5 months), fish (>8.2 months), and eggs (>10.5 months), was associated with increased sensitization to food allergens at 5 years of age. For this study the median age at the introduction of the first solid food was 3.5 months (range: 0.7-10.0 months) and potatoes were the earliest food introduced to the children. Allergic sensitization to any food was present in 17% of the children with high rates (12%) of cow's milk sensitisation at 5 years of age, although no food allergy clinical symptom data was provided. There was also no data on peanut or tree nut sensitization, which are more common food allergens in many populations at 5 years of age
    • Nwaru BI, Erkkola M, Ahonen S, Kaila M, Haapala AM, Kronberg-Kippila C, et al. Age at the introduction of solid foods during the first year and allergic sensitization at age 5 years. Pediatrics. 2010;125:50-9. In this study, delayed introduction of specific foods, in particular potatoes (>4 months), oats (>5 months), rye (>7 months), wheat (>6 months), meat (>5.5 months), fish (>8.2 months), and eggs (>10.5 months), was associated with increased sensitization to food allergens at 5 years of age. For this study the median age at the introduction of the first solid food was 3.5 months (range: 0.7-10.0 months) and potatoes were the earliest food introduced to the children. Allergic sensitization to any food was present in 17% of the children with high rates (12%) of cow's milk sensitisation at 5 years of age, although no food allergy clinical symptom data was provided. There was also no data on peanut or tree nut sensitization, which are more common food allergens in many populations at 5 years of age.
    • (2010) Pediatrics , vol.125 , pp. 50-9
    • Nwaru, B.I.1    Erkkola, M.2    Ahonen, S.3    Kaila, M.4    Haapala, A.M.5    Kronberg-Kippila, C.6
  • 40
    • 77957765841 scopus 로고    scopus 로고
    • Can early introduction of egg prevent egg allergy in infants? A population-based study
    • This crossectional study investigated the relationship between introduction of solid foods on the outcome of egg allergy at 1 year of age. The children were skin prick tested to egg and inpatient oral food challenges to raw egg white were performed. Delayed introduction of egg at 10-12 months adjusted OR 16 95% CI 10-26 or after 12 months adjusted OR 34 95% CI 18-65 was associated with significantly higher risk of egg comared with introduction at 4 to 6 months There were rigorous attemts to adjust for reverse causation and the findings ersisted after adjusting for family history of allergy and infant allergy symtoms
    • Koplin JJ, Osborne NJ, Wake M, Martin PE, Gurrin LC, Robinson MN, et al. Can early introduction of egg prevent egg allergy in infants? A population-based study. J Allergy Clin Immunol. 2010;126:807-13. This crossectional study investigated the relationship between introduction of solid foods on the outcome of egg allergy at 1 year of age. The children were skin prick tested to egg and inpatient oral food challenges to raw egg white were performed. Delayed introduction of egg at 10-12 months (adjusted OR, 1.6, 95% CI, 1.0-2.6) or after 12 months (adjusted OR 3.4, 95% CI, 1.8-6.5) was associated with significantly higher risk of egg compared with introduction at 4 to 6 months. There were rigorous attempts to adjust for reverse causation and the findings persisted after adjusting for family history of allergy and infant allergy symptoms.
    • (2010) J Allergy Clin Immunol. , vol.126 , pp. 807-13
    • Koplin, J.J.1    Osborne, N.J.2    Wake, M.3    Martin, P.E.4    Gurrin, L.C.5    Robinson, M.N.6
  • 43
    • 11344286028 scopus 로고    scopus 로고
    • Oral tolerance and its relation to food hypersensitivities
    • Chehade M, Mayer L. Oral tolerance and its relation to food hypersensitivities. J Allergy Clin Immunol. 2005;115:3-12.
    • (2005) J Allergy Clin Immunol. , vol.115 , pp. 3-12
    • Chehade, M.1    Mayer, L.2
  • 44
    • 14844340205 scopus 로고    scopus 로고
    • Effect of cooked and raw egg consumption on ovalbumin content of human milk: A randomized, double-blind, cross-over trial
    • DOI 10.1111/j.1365-2222.2005.02170.x
    • Palmer DJ, Gold MS, Makrides M Effect of cooked and raw egg consumption on ovalbumin content of human milk: a randomized, double-blind, cross-over trial. Clin Exp Allergy. 2005;35:173-8. (Pubitemid 40353779)
    • (2005) Clinical and Experimental Allergy , vol.35 , Issue.2 , pp. 173-178
    • Palmer, D.J.1    Gold, M.S.2    Makrides, M.3
  • 45
    • 33644837165 scopus 로고    scopus 로고
    • Exposure of the fetus and infant to hens' egg ovalbumin via the placenta and breast milk in relation to maternal intake of dietary egg
    • Vance GH, Lewis SA, Grimshaw KE, Wood PJ, Briggs RA, Thornton CA, et al. Exposure of the fetus and infant to hens' egg ovalbumin via the placenta and breast milk in relation to maternal intake of dietary egg. Clin Exp Allergy. 2005;35:1318-26.
    • (2005) Clin Exp Allergy , vol.35 , pp. 1318-1326
    • Vance, G.H.1    Lewis, S.A.2    Grimshaw, K.E.3    Wood, P.J.4    Briggs, R.A.5    Thornton, C.A.6
  • 46
    • 54449093083 scopus 로고    scopus 로고
    • Effect of maternal egg consumption on breast milk ovalbumin concentration
    • Palmer DJ, Gold MS, Makrides M Effect of maternal egg consumption on breast milk ovalbumin concentration. Clin Exp Allergy. 2008;38:1186-91.
    • (2008) Clin Exp Allergy , vol.38 , pp. 1186-1191
    • Palmer, D.J.1    Gold, M.S.2    Makrides, M.3
  • 47
    • 77953753712 scopus 로고    scopus 로고
    • Breast milk immune complexes are potent inducers of oral tolerance in neonates and prevent asthma development
    • Mosconi E, Rekima A, Seitz-Polski B, Kanda A, Fleury S, Tissandie E, et al. Breast milk immune complexes are potent inducers of oral tolerance in neonates and prevent asthma development. Mucosal Immunol. 2010;3:461-74.
    • (2010) Mucosal Immunol , vol.3 , pp. 461-474
    • Mosconi, E.1    Rekima, A.2    Seitz-Polski, B.3    Kanda, A.4    Fleury, S.5    Tissandie, E.6
  • 50
    • 44649200479 scopus 로고    scopus 로고
    • Epidemiologic risks for food allergy
    • DOI 10.1016/j.jaci.2008.04.032, PII S0091674908007781
    • Lack G. Epidemiologic risks for food allergy. J Allergy Clin Immunol. 2008;121:1331-6. (Pubitemid 351787358)
    • (2008) Journal of Allergy and Clinical Immunology , vol.121 , Issue.6 , pp. 1331-1336
    • Lack, G.1
  • 51
    • 59649122938 scopus 로고    scopus 로고
    • Household peanut consumption as a risk factor for the development of peanut allergy
    • Fox AT, Sasieni P, du Toit G, Syed H, Lack G. Household peanut consumption as a risk factor for the development of peanut allergy. J Allergy Clin Immunol. 2009;123:417-23.
    • (2009) J Allergy Clin Immunol , vol.123 , pp. 417-423
    • Fox, A.T.1    Sasieni, P.2    Du Toit, G.3    Syed, H.4    Lack, G.5
  • 56
    • 57349108583 scopus 로고    scopus 로고
    • Maternal alloantigens promote the development of tolerogenic fetal regulatory t cells in utero
    • Mold JE, Michaelsson J, Burt TD, Muench MO, Beckerman KP, Busch MP, et al. Maternal alloantigens promote the development of tolerogenic fetal regulatory T cells in utero. Science. 2008;322:1562-5.
    • (2008) Science , vol.322 , pp. 1562-1565
    • Mold, J.E.1    Michaelsson, J.2    Burt, T.D.3    Muench, M.O.4    Beckerman, K.P.5    Busch, M.P.6
  • 57
    • 79952763423 scopus 로고    scopus 로고
    • Human cord blood cd4+cd25hi regulatory t cells suppress prenatally acquired t cell responses to plasmodium falciparum antigens
    • This study illustrates how in utero exposure to antigens (Plasmodium falciparum) can induce malaria-specific regulatory T cells in utero, with evidence that this prenatal exposure primarily suppresses Th1-type recall responses. It is proposed that persistence of these memory Tregs postnatally could modify a child's susceptibility to malaria infection and disease. This is in keeping with long-lived fetal regulatory memory responses to alloantigens in other studies, and raises questions about the role of fetal regulatory responses to allergens encountered in the same period
    • Mackroth MS, Malhotra I, Mungai P, Koech D, Muchiri E, King CL. Human cord blood CD4+CD25hi regulatory T cells suppress prenatally acquired T cell responses to Plasmodium falciparum antigens. J Immunol. 2011; 86:2780-91. This study illustrates how in utero exposure to antigens (Plasmodium falciparum) can induce malaria-specific regulatory T cells in utero, with evidence that this prenatal exposure primarily suppresses Th1-type recall responses. It is proposed that persistence of these memory Tregs postnatally could modify a child's susceptibility to malaria infection and disease. This is in keeping with long-lived fetal regulatory memory responses to alloantigens in other studies, and raises questions about the role of fetal regulatory responses to allergens encountered in the same period.
    • (2011) J Immunol. , vol.86 , pp. 2780-91
    • Mackroth, M.S.1    Malhotra, I.2    Mungai, P.3    Koech, D.4    Muchiri, E.5    King, C.L.6
  • 59
    • 0032524991 scopus 로고    scopus 로고
    • Transplacental priming of the human immune system to environmental allergens: Universal skewing of initial T cell responses toward the Th2 cytokine profile
    • Prescott S, Macaubas C, Holt B, Smallacombe T, Loh R, Sly P. Transplacental priming of the human immune system to environmental allergens: universal skewing of initial T-cell responses towards Th-2 cytokine profile. J Immunol. 1998;160:4730-7. (Pubitemid 28215305)
    • (1998) Journal of Immunology , vol.160 , Issue.10 , pp. 4730-4737
    • Prescott, S.L.1    Macaubas, C.2    Holt, B.J.3    Smallacombe, T.B.4    Loh, R.5    Sly, P.D.6    Holt, P.G.7
  • 60
    • 0030467722 scopus 로고    scopus 로고
    • Fetal peripheral blood mononuclear cell proliferative responses to mitogenic and allergenic stimuli during gestation
    • Jones AC, Miles EA, Warner JO, Colwell BM, Bryant TN, Warner JA. Fetal peripheral blood mononuclear cell proliferative responses to mitogenic and allergenic stimuli during gestation. Pediatr Allergy Immunol. 1996;7:109-16. (Pubitemid 27042613)
    • (1996) Pediatric Allergy and Immunology , vol.7 , Issue.3 , pp. 109-116
    • Jones, A.C.1    Miles, E.A.2    Warner, J.O.3    Colwell, B.M.4    Bryant, T.N.5    Warner, J.A.6
  • 61
    • 79952126441 scopus 로고    scopus 로고
    • Tissue-based class control: The other side of tolerance
    • This excellent review paper offers a new perspective on how immune responses are regulated. It focuses on the importance of local tissue factors in the determination of effector class
    • Matzinger P, Kamala T. Tissue-based class control: the other side of tolerance. Nat Rev Immunol. 2011;11:221-30. This excellent review paper offers a new perspective on how immune responses are regulated. It focuses on the importance of local tissue factors in the determination of effector class.
    • (2011) Nat Rev Immunol. , vol.11 , pp. 221-30
    • Matzinger, P.1    Kamala, T.2
  • 62
  • 63
    • 70349510224 scopus 로고    scopus 로고
    • Comparison of the immunomodulatory properties of three probiotic strains of lactobacilli using complex culture systems: Prediction for in vivo efficacy
    • Mileti E, Matteoli G, Iliev ID, Rescigno M Comparison of the immunomodulatory properties of three probiotic strains of Lactobacilli using complex culture systems: prediction for in vivo efficacy. PLoS One. 2009;4:e7056.
    • (2009) PLoS One. , vol.4
    • Mileti, E.1    Matteoli, G.2    Iliev, I.D.3    Rescigno, M.4
  • 64
    • 57149145441 scopus 로고    scopus 로고
    • Cigarette smoke extract induces thymic stromal lymphopoietin expression, leading to t(h)2-type immune responses and airway inflammation
    • Nakamura Y, Miyata M, Ohba T, Ando T, Hatsushika K, Suenaga F, et al. Cigarette smoke extract induces thymic stromal lymphopoietin expression, leading to T(H)2-type immune responses and airway inflammation. J Allergy Clin Immunol. 2008;122:1208-14.
    • (2008) J Allergy Clin Immunol , vol.122 , pp. 1208-1214
    • Nakamura, Y.1    Miyata, M.2    Ohba, T.3    Ando, T.4    Hatsushika, K.5    Suenaga, F.6
  • 65
    • 79960562675 scopus 로고    scopus 로고
    • Dietary docosahexaenoic acid in combination with arachidonic acid ameliorates allergen-induced dermatitis in mice
    • Weise C, Heunemann C, Loddenkemper C, Herz U, van Tol EA, Worm M Dietary docosahexaenoic acid in combination with arachidonic acid ameliorates allergen-induced dermatitis in mice. Pediatr Allergy Immunol. 2011;22:497-504.
    • (2011) Pediatr Allergy Immunol , vol.22 , pp. 497-504
    • Weise, C.1    Heunemann, C.2    Loddenkemper, C.3    Herz, U.4    Van Tol, E.A.5    Worm, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.