Incorporation of sciadonic acid into cellular phospholipids reduces pro-inflammatory mediators in murine macrophages through NF-κB and MAPK signaling pathways

Food and Chemical Toxicology

Volumn 50, Issue 10, 2012, Pages 3687-3695

  Chen, Szu Jung ^a   Huang, Wen Cheng ^b   Yang, Tzu Ting ^c   Lu, Jui Hua ^a   Chuang, Lu Te ^c  

^a TAO YUAN GENERAL HOSPITAL   (Taiwan)

^b NATIONAL TAIWAN NORMAL UNIVERSITY   (Taiwan)

^c YUANPEI UNIVERSITY   (Taiwan)

Author keywords

Arachidonic acid; Macrophage; MAPK; NF B; Prostaglandin E2; Sciadonic acid

Indexed keywords

ARACHIDONIC ACID; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOUNSATURATED FATTY ACID; NITRIC OXIDE; PHOSPHOLIPID; POLYUNSATURATED FATTY ACID; PROSTAGLANDIN E2; SATURATED FATTY ACID; SCIADONIC ACID; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; DRUG PURIFICATION; ENZYME PHOSPHORYLATION; MACROPHAGE; MEDICINAL PLANT; MOUSE; NONHUMAN; PLANT SEED; PODOCARPUS NAGI; PROSTAGLANDIN SYNTHESIS INHIBITION; PROTEIN EXPRESSION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARACHIDONIC ACIDS; CYCLOOXYGENASE 2; GENE EXPRESSION REGULATION; MACROPHAGES; MICE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHOLIPIDS; SIGNAL TRANSDUCTION;

MURINAE; NAGEIA NAGI;

EID: 84865510906     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.07.057     Document Type: Article

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