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Volumn 30, Issue 5, 2011, Pages 678-687

Anti-inflammatory and anti-angiogenic effect of long chain n-3 polyunsaturated fatty acids in intestinal microvascular endothelium

Author keywords

Colitis; Endothelium; HIMEC; Inflammation; N 3 PUFA

Indexed keywords

CYCLOOXYGENASE 2; DOCOSAHEXAENOIC ACID; FISH OIL; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; I KAPPA B KINASE; ICOSAPENTAENOIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LEUKOTRIENE B4; OMEGA 3 FATTY ACID; PROSTAGLANDIN E2; TOLL LIKE RECEPTOR 4; TRINITROBENZENESULFONIC ACID; VASCULAR CELL ADHESION MOLECULE 1; VASCULOTROPIN RECEPTOR 2;

EID: 80053904495     PISSN: 02615614     EISSN: 15321983     Source Type: Journal    
DOI: 10.1016/j.clnu.2011.05.002     Document Type: Article
Times cited : (97)

References (48)
  • 1
    • 44849118823 scopus 로고    scopus 로고
    • Multiple pathogenic roles of microvasculature in inflammatory bowel disease: a Jack of all trades
    • Deban L., Correale C., Vetrano S., Malesci A., Danese S. Multiple pathogenic roles of microvasculature in inflammatory bowel disease: a Jack of all trades. Am J Pathol 2008, 172:1457-1466.
    • (2008) Am J Pathol , vol.172 , pp. 1457-1466
    • Deban, L.1    Correale, C.2    Vetrano, S.3    Malesci, A.4    Danese, S.5
  • 2
    • 0030001831 scopus 로고    scopus 로고
    • Cytokine-regulated expression of E-selectin, intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1 (VCAM-1) in human microvascular endothelial cells
    • Haraldsen G., Kvale D., Lien B., Farstad I.N., Brandtzaeg P. Cytokine-regulated expression of E-selectin, intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1 (VCAM-1) in human microvascular endothelial cells. J Immunol 1996, 156:2558-2565.
    • (1996) J Immunol , vol.156 , pp. 2558-2565
    • Haraldsen, G.1    Kvale, D.2    Lien, B.3    Farstad, I.N.4    Brandtzaeg, P.5
  • 3
    • 33644691914 scopus 로고    scopus 로고
    • Anti-inflammatory effect of docosahexaenoic acid on cytokine-induced adhesion molecule expression in human retinal vascular endothelial cells
    • Chen W., Esselman W.J., Jump D.B., Busik J.V. Anti-inflammatory effect of docosahexaenoic acid on cytokine-induced adhesion molecule expression in human retinal vascular endothelial cells. Invest Ophthalmol Vis Sci 2005, 46:4342-4347.
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 4342-4347
    • Chen, W.1    Esselman, W.J.2    Jump, D.B.3    Busik, J.V.4
  • 4
    • 42249104381 scopus 로고    scopus 로고
    • Comparison of cytokine modulation by natural peroxisome proliferator-activated receptor {gamma} ligands with synthetic ligands in intestinal-like Caco-2 cells and human dendritic cells-potential for dietary modulation of peroxisome proliferator-activated receptor {gamma} in intestinal inflammation
    • Marion-Letellier R., Butler M., Dechelotte P., Playford R.J., Ghosh S. Comparison of cytokine modulation by natural peroxisome proliferator-activated receptor {gamma} ligands with synthetic ligands in intestinal-like Caco-2 cells and human dendritic cells-potential for dietary modulation of peroxisome proliferator-activated receptor {gamma} in intestinal inflammation. Am J Clin Nutr 2008, 87:939-948.
    • (2008) Am J Clin Nutr , vol.87 , pp. 939-948
    • Marion-Letellier, R.1    Butler, M.2    Dechelotte, P.3    Playford, R.J.4    Ghosh, S.5
  • 5
    • 0028172777 scopus 로고
    • The omega-3 fatty acid docosahexaenoate reduces cytokine-induced expression of proatherogenic and proinflammatory proteins in human endothelial cells
    • De Caterina R., Cybulsky M.I., Clinton S.K., Gimbrone M.A., Libby P. The omega-3 fatty acid docosahexaenoate reduces cytokine-induced expression of proatherogenic and proinflammatory proteins in human endothelial cells. Arterioscler Thromb 1994, 14:1829-1836.
    • (1994) Arterioscler Thromb , vol.14 , pp. 1829-1836
    • De Caterina, R.1    Cybulsky, M.I.2    Clinton, S.K.3    Gimbrone, M.A.4    Libby, P.5
  • 6
    • 31144440919 scopus 로고    scopus 로고
    • Effect of fish oil enriched enteral diet on inflammatory bowel disease tissues in organ culture: differential effects on ulcerative colitis and Crohn's disease
    • Meister D., Ghosh S. Effect of fish oil enriched enteral diet on inflammatory bowel disease tissues in organ culture: differential effects on ulcerative colitis and Crohn's disease. World J Gastroenterol 2005, 11:7466-7472.
    • (2005) World J Gastroenterol , vol.11 , pp. 7466-7472
    • Meister, D.1    Ghosh, S.2
  • 7
    • 0029890380 scopus 로고    scopus 로고
    • Inhibitory effect of fish oil N-3 polyunsaturated fatty acids on the expression of endothelial cell adhesion molecules
    • Collie-Duguid E.S., Wahle K.W. Inhibitory effect of fish oil N-3 polyunsaturated fatty acids on the expression of endothelial cell adhesion molecules. Biochem Biophys Res Commun 1996, 220:969-974.
    • (1996) Biochem Biophys Res Commun , vol.220 , pp. 969-974
    • Collie-Duguid, E.S.1    Wahle, K.W.2
  • 8
    • 0038143617 scopus 로고    scopus 로고
    • Differential modulation of Toll-like receptors by fatty acids: preferential inhibition by n-3 polyunsaturated fatty acids
    • Lee J.Y., Plakidas A., Lee W.H., Heikkinen A., Chanmugam P., Bray G., et al. Differential modulation of Toll-like receptors by fatty acids: preferential inhibition by n-3 polyunsaturated fatty acids. J Lipid Res 2003, 44:479-486.
    • (2003) J Lipid Res , vol.44 , pp. 479-486
    • Lee, J.Y.1    Plakidas, A.2    Lee, W.H.3    Heikkinen, A.4    Chanmugam, P.5    Bray, G.6
  • 9
    • 77958131022 scopus 로고    scopus 로고
    • An alpha-linolenic acid-rich formula reduces oxidative stress and inflammation by regulating NF-kappaB in rats with TNBS-induced colitis
    • Hassan A., Ibrahim A., Mbodji K., Coeffier M., Ziegler F., Bounoure F., et al. An alpha-linolenic acid-rich formula reduces oxidative stress and inflammation by regulating NF-kappaB in rats with TNBS-induced colitis. J Nutr 2010, 140:1714-1721.
    • (2010) J Nutr , vol.140 , pp. 1714-1721
    • Hassan, A.1    Ibrahim, A.2    Mbodji, K.3    Coeffier, M.4    Ziegler, F.5    Bounoure, F.6
  • 10
    • 0027279434 scopus 로고
    • Polyunsaturated fatty acid pattern and fish oil treatment in inflammatory bowel disease
    • Belluzzi A., Campieri M., Brignola C., Gionchetti P., Miglioli M., Barbara L. Polyunsaturated fatty acid pattern and fish oil treatment in inflammatory bowel disease. Gut 1993, 34:1289-1290.
    • (1993) Gut , vol.34 , pp. 1289-1290
    • Belluzzi, A.1    Campieri, M.2    Brignola, C.3    Gionchetti, P.4    Miglioli, M.5    Barbara, L.6
  • 12
    • 41949118078 scopus 로고    scopus 로고
    • Omega-3 free fatty acids for the maintenance of remission in Crohn disease: the EPIC Randomized Controlled Trials
    • Feagan B.G., Sandborn W.J., Mittmann U., Bar-Meir S., D'Haens G., Bradette M., et al. Omega-3 free fatty acids for the maintenance of remission in Crohn disease: the EPIC Randomized Controlled Trials. JAMA 2008, 299:1690-1697.
    • (2008) JAMA , vol.299 , pp. 1690-1697
    • Feagan, B.G.1    Sandborn, W.J.2    Mittmann, U.3    Bar-Meir, S.4    D'Haens, G.5    Bradette, M.6
  • 14
    • 64149109679 scopus 로고    scopus 로고
    • Dietary modulation of peroxisome proliferator-activated receptor gamma
    • Marion-Letellier R., Dechelotte P., Iacucci M., Ghosh S. Dietary modulation of peroxisome proliferator-activated receptor gamma. Gut 2009, 58:586-593.
    • (2009) Gut , vol.58 , pp. 586-593
    • Marion-Letellier, R.1    Dechelotte, P.2    Iacucci, M.3    Ghosh, S.4
  • 15
    • 38049050752 scopus 로고    scopus 로고
    • Regulation of adhesion molecule expression in human endothelial and smooth muscle cells by omega-3 fatty acids and conjugated linoleic acids: Involvement of the transcription factor NF-[kappa]B?
    • Goua M., Mulgrew S., Frank J., Rees D., Sneddon A.A., Wahle K.W.J. Regulation of adhesion molecule expression in human endothelial and smooth muscle cells by omega-3 fatty acids and conjugated linoleic acids: Involvement of the transcription factor NF-[kappa]B?. Prostaglandins, Leukot Essent Fatty Acids 2008, 78:33-43.
    • (2008) Prostaglandins, Leukot Essent Fatty Acids , vol.78 , pp. 33-43
    • Goua, M.1    Mulgrew, S.2    Frank, J.3    Rees, D.4    Sneddon, A.A.5    Wahle, K.W.J.6
  • 17
    • 45749114465 scopus 로고    scopus 로고
    • Effects of docosahexaenoic acid-rich n-3 fatty acid supplementation on cytokine release from blood mononuclear leukocytes: the OmegAD study
    • Vedin I., Cederholm T., Freund Levi Y., Basun H., Garlind A., Faxen Irving G., et al. Effects of docosahexaenoic acid-rich n-3 fatty acid supplementation on cytokine release from blood mononuclear leukocytes: the OmegAD study. Am J Clin Nutr 2008, 87:1616-1622.
    • (2008) Am J Clin Nutr , vol.87 , pp. 1616-1622
    • Vedin, I.1    Cederholm, T.2    Freund Levi, Y.3    Basun, H.4    Garlind, A.5    Faxen Irving, G.6
  • 18
    • 16244405611 scopus 로고    scopus 로고
    • Dietary olive oil supplemented with fish oil, rich in EPA and DHA (n-3) polyunsaturated fatty acids, attenuates colonic inflammation in rats with DSS-induced colitis
    • Camuesco D., Galvez J., Nieto A., Comalada M., Rodriguez-Cabezas M.E., Concha A., et al. Dietary olive oil supplemented with fish oil, rich in EPA and DHA (n-3) polyunsaturated fatty acids, attenuates colonic inflammation in rats with DSS-induced colitis. J Nutr 2005, 135:687-694.
    • (2005) J Nutr , vol.135 , pp. 687-694
    • Camuesco, D.1    Galvez, J.2    Nieto, A.3    Comalada, M.4    Rodriguez-Cabezas, M.E.5    Concha, A.6
  • 19
    • 33746885901 scopus 로고    scopus 로고
    • Intestinal anti-inflammatory activity of combined quercitrin and dietary olive oil supplemented with fish oil, rich in EPA and DHA (n-3) polyunsaturated fatty acids, in rats with DSS-induced colitis
    • Camuesco D., Comalada M., Concha A., Nieto A., Sierra S., Xaus J., et al. Intestinal anti-inflammatory activity of combined quercitrin and dietary olive oil supplemented with fish oil, rich in EPA and DHA (n-3) polyunsaturated fatty acids, in rats with DSS-induced colitis. Clin Nutr 2006, 25:466-476.
    • (2006) Clin Nutr , vol.25 , pp. 466-476
    • Camuesco, D.1    Comalada, M.2    Concha, A.3    Nieto, A.4    Sierra, S.5    Xaus, J.6
  • 20
    • 33746625086 scopus 로고    scopus 로고
    • Transgenic mice rich in endogenous omega-3 fatty acids are protected from colitis
    • Hudert C.A., Weylandt K.H., Lu Y., Wang J., Hong S., Dignass A., et al. Transgenic mice rich in endogenous omega-3 fatty acids are protected from colitis. Proc Natl Acad Sci U S A 2006, 103:11276-11281.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 11276-11281
    • Hudert, C.A.1    Weylandt, K.H.2    Lu, Y.3    Wang, J.4    Hong, S.5    Dignass, A.6
  • 21
    • 0028784582 scopus 로고
    • Therapeutic efficacy of N-3 polyunsaturated fatty acid in experimental Crohn's disease
    • Shoda R., Matsueda K., Yamato S., Umeda N. Therapeutic efficacy of N-3 polyunsaturated fatty acid in experimental Crohn's disease. J Gastroenterol 1995, 8(30 Suppl):98-101.
    • (1995) J Gastroenterol , vol.8 , Issue.30 SUPPL. , pp. 98-101
    • Shoda, R.1    Matsueda, K.2    Yamato, S.3    Umeda, N.4
  • 22
    • 39749122734 scopus 로고    scopus 로고
    • The opposing effects of n-3 and n-6 fatty acids
    • Schmitz G., Ecker J. The opposing effects of n-3 and n-6 fatty acids. Prog Lipid Res 2008, 47:147-155.
    • (2008) Prog Lipid Res , vol.47 , pp. 147-155
    • Schmitz, G.1    Ecker, J.2
  • 23
    • 0031902251 scopus 로고    scopus 로고
    • Cyclooxygenase 2 is induced in colonic epithelial cells in inflammatory bowel disease
    • Singer, Kawka D.W., Schloemann S., Tessner T., Riehl T., Stenson W.F. Cyclooxygenase 2 is induced in colonic epithelial cells in inflammatory bowel disease. Gastroenterology 1998, 115:297-306.
    • (1998) Gastroenterology , vol.115 , pp. 297-306
    • Singer1    Kawka, D.W.2    Schloemann, S.3    Tessner, T.4    Riehl, T.5    Stenson, W.F.6
  • 24
    • 0037318901 scopus 로고    scopus 로고
    • The effects of fish oil, olive oil, oleic acid and linoleic acid on colorectal neoplastic processes
    • Llor X., Pons E., Roca A., Alvarez M., Mane J., Fernandez-Banares F., et al. The effects of fish oil, olive oil, oleic acid and linoleic acid on colorectal neoplastic processes. Clin Nutr 2003, 22:71-79.
    • (2003) Clin Nutr , vol.22 , pp. 71-79
    • Llor, X.1    Pons, E.2    Roca, A.3    Alvarez, M.4    Mane, J.5    Fernandez-Banares, F.6
  • 25
    • 33645850713 scopus 로고    scopus 로고
    • CXCL1 induced by prostaglandin E2 promotes angiogenesis in colorectal cancer
    • Wang D., Wang H., Brown J., Daikoku T., Ning W., Shi Q., et al. CXCL1 induced by prostaglandin E2 promotes angiogenesis in colorectal cancer. J Exp Med 2006, 203:941-951.
    • (2006) J Exp Med , vol.203 , pp. 941-951
    • Wang, D.1    Wang, H.2    Brown, J.3    Daikoku, T.4    Ning, W.5    Shi, Q.6
  • 26
    • 33750059762 scopus 로고    scopus 로고
    • The omega-3 fatty acid docosahexaenoate attenuates endothelial cyclooxygenase-2 induction through both NADP(H) oxidase and PKCÎμ inhibition
    • Massaro M., Habib A., Lubrano L., Turco S.D., Lazzerini G., Bourcier T., et al. The omega-3 fatty acid docosahexaenoate attenuates endothelial cyclooxygenase-2 induction through both NADP(H) oxidase and PKCÎμ inhibition. Proc Natl Acad Sci 2006, 103:15184-15189.
    • (2006) Proc Natl Acad Sci , vol.103 , pp. 15184-15189
    • Massaro, M.1    Habib, A.2    Lubrano, L.3    Turco, S.D.4    Lazzerini, G.5    Bourcier, T.6
  • 27
    • 54349091392 scopus 로고    scopus 로고
    • Curcumin inhibits VEGF-mediated angiogenesis in human intestinal microvascular endothelial cells through COX-2 and MAPK inhibition
    • Binion D.G., Otterson M.F., Rafiee P. Curcumin inhibits VEGF-mediated angiogenesis in human intestinal microvascular endothelial cells through COX-2 and MAPK inhibition. Gut 2008, 57:1509-1517.
    • (2008) Gut , vol.57 , pp. 1509-1517
    • Binion, D.G.1    Otterson, M.F.2    Rafiee, P.3
  • 28
    • 34147144135 scopus 로고    scopus 로고
    • Polyunsaturated fatty acid supplementation alters proinflammatory gene expression and reduces the incidence of necrotizing enterocolitis in a neonatal rat model
    • Lu J., Jilling T., Li D., Caplan M.S. Polyunsaturated fatty acid supplementation alters proinflammatory gene expression and reduces the incidence of necrotizing enterocolitis in a neonatal rat model. Pediatr Res 2007, 61:427-432.
    • (2007) Pediatr Res , vol.61 , pp. 427-432
    • Lu, J.1    Jilling, T.2    Li, D.3    Caplan, M.S.4
  • 29
    • 77956304288 scopus 로고    scopus 로고
    • Immunoregulatory actions of epithelial cell PPAR gamma at the colonic mucosa of mice with experimental inflammatory bowel disease
    • Mohapatra S.K., Guri A.J., Climent M., Vives C., Carbo A., Horne W.T., et al. Immunoregulatory actions of epithelial cell PPAR gamma at the colonic mucosa of mice with experimental inflammatory bowel disease. PLoS One 2010, 5:e10215.
    • (2010) PLoS One , vol.5
    • Mohapatra, S.K.1    Guri, A.J.2    Climent, M.3    Vives, C.4    Carbo, A.5    Horne, W.T.6
  • 30
    • 33646772865 scopus 로고    scopus 로고
    • Eicosapentaenoic acid and docosahexaenoic acid modulate mitogen-activated protein kinase activity in endothelium
    • Xue H., Wan M., Song D., Li Y., Li J. Eicosapentaenoic acid and docosahexaenoic acid modulate mitogen-activated protein kinase activity in endothelium. Vasc Pharmacol 2006, 44:434-439.
    • (2006) Vasc Pharmacol , vol.44 , pp. 434-439
    • Xue, H.1    Wan, M.2    Song, D.3    Li, Y.4    Li, J.5
  • 31
    • 33746772121 scopus 로고    scopus 로고
    • Adipose tissue inflammation induced by high-fat diet in obese diabetic mice is prevented by n-3 polyunsaturated fatty acids
    • Todoric J., Löffler M., Huber J., Bilban M., Reimers M., Kadl A., et al. Adipose tissue inflammation induced by high-fat diet in obese diabetic mice is prevented by n-3 polyunsaturated fatty acids. Diabetologia 2006, 49:2109-2119.
    • (2006) Diabetologia , vol.49 , pp. 2109-2119
    • Todoric, J.1    Löffler, M.2    Huber, J.3    Bilban, M.4    Reimers, M.5    Kadl, A.6
  • 32
    • 78650653253 scopus 로고    scopus 로고
    • Interleukin-1 drives cerebrovascular inflammation via MAP kinase-independent pathways
    • Thornton P., McColl B.W., Cooper L., Rothwell N.J., Allan S.M. Interleukin-1 drives cerebrovascular inflammation via MAP kinase-independent pathways. Curr Neurovasc Res 2010, 7:330-340.
    • (2010) Curr Neurovasc Res , vol.7 , pp. 330-340
    • Thornton, P.1    McColl, B.W.2    Cooper, L.3    Rothwell, N.J.4    Allan, S.M.5
  • 33
    • 34447101284 scopus 로고    scopus 로고
    • Fenofibrate represses interleukin-17 and interferon-gamma expression and improves colitis in interleukin-10-deficient mice
    • Lee J.W., Bajwa P.J., Carson M.J., Jeske D.R., Cong Y., Elson C.O., et al. Fenofibrate represses interleukin-17 and interferon-gamma expression and improves colitis in interleukin-10-deficient mice. Gastroenterology 2007, 133:108-123.
    • (2007) Gastroenterology , vol.133 , pp. 108-123
    • Lee, J.W.1    Bajwa, P.J.2    Carson, M.J.3    Jeske, D.R.4    Cong, Y.5    Elson, C.O.6
  • 35
    • 0035808255 scopus 로고    scopus 로고
    • Eicosapentaenoic acid (EPA) induces Ca(2+)-independent activation and translocation of endothelial nitric oxide synthase and endothelium-dependent vasorelaxation
    • Omura M., Kobayashi S., Mizukami Y., Mogami K., Todoroki-Ikeda N., Miyake T., et al. Eicosapentaenoic acid (EPA) induces Ca(2+)-independent activation and translocation of endothelial nitric oxide synthase and endothelium-dependent vasorelaxation. FEBS Lett 2001, 487:361-366.
    • (2001) FEBS Lett , vol.487 , pp. 361-366
    • Omura, M.1    Kobayashi, S.2    Mizukami, Y.3    Mogami, K.4    Todoroki-Ikeda, N.5    Miyake, T.6
  • 36
    • 58649111743 scopus 로고    scopus 로고
    • VEGF-A links angiogenesis and inflammation in inflammatory bowel disease pathogenesis
    • e5
    • Scaldaferri F., Vetrano S., Sans M., Arena V., Straface G., Stigliano E., et al. VEGF-A links angiogenesis and inflammation in inflammatory bowel disease pathogenesis. Gastroenterology 2009, 136:585-595. e5.
    • (2009) Gastroenterology , vol.136 , pp. 585-595
    • Scaldaferri, F.1    Vetrano, S.2    Sans, M.3    Arena, V.4    Straface, G.5    Stigliano, E.6
  • 37
    • 33744937585 scopus 로고    scopus 로고
    • CLA and n-3 PUFA differentially modulate clinical activity and colonic PPAR-responsive gene expression in a pig model of experimental IBD
    • Bassaganya-Riera J., Hontecillas R. CLA and n-3 PUFA differentially modulate clinical activity and colonic PPAR-responsive gene expression in a pig model of experimental IBD. Clin Nutr 2006, 25:454-465.
    • (2006) Clin Nutr , vol.25 , pp. 454-465
    • Bassaganya-Riera, J.1    Hontecillas, R.2
  • 38
    • 68149106145 scopus 로고    scopus 로고
    • Punicic acid a conjugated linolenic acid inhibits TNFalpha-induced neutrophil hyperactivation and protects from experimental colon inflammation in rats
    • Boussetta T., Raad H., Letteron P., Gougerot-Pocidalo M.A., Marie J.C., Driss F., et al. Punicic acid a conjugated linolenic acid inhibits TNFalpha-induced neutrophil hyperactivation and protects from experimental colon inflammation in rats. PLoS One 2009, 4:e6458.
    • (2009) PLoS One , vol.4
    • Boussetta, T.1    Raad, H.2    Letteron, P.3    Gougerot-Pocidalo, M.A.4    Marie, J.C.5    Driss, F.6
  • 39
    • 0345688219 scopus 로고    scopus 로고
    • Fowler Iii AA, Graham MF. Linoleic acid, but not oleic acid, upregulates the production of interleukin-8 by human intestinal smooth muscle cells isolated from patients with Crohn's disease
    • Alzoghaibi M.A., Walsh S.W., Willey A. Fowler Iii AA, Graham MF. Linoleic acid, but not oleic acid, upregulates the production of interleukin-8 by human intestinal smooth muscle cells isolated from patients with Crohn's disease. Clin Nutr 2003, 22:529-535.
    • (2003) Clin Nutr , vol.22 , pp. 529-535
    • Alzoghaibi, M.A.1    Walsh, S.W.2    Willey, A.3
  • 40
    • 78349294219 scopus 로고    scopus 로고
    • Dietary oleic acid as a control fatty acid for polyunsaturated fatty acid intervention studies: a transcriptomics and proteomics investigation using interleukin-10 gene-deficient mice
    • n/a-n/a
    • Knoch B., Barnett M.P.G., Cooney J., McNabb W.C., Barraclough D., Laing W., et al. Dietary oleic acid as a control fatty acid for polyunsaturated fatty acid intervention studies: a transcriptomics and proteomics investigation using interleukin-10 gene-deficient mice. Biotechnol J 2010, n/a-n/a.
    • (2010) Biotechnol J
    • Knoch, B.1    Barnett, M.P.G.2    Cooney, J.3    McNabb, W.C.4    Barraclough, D.5    Laing, W.6
  • 41
    • 78650966362 scopus 로고    scopus 로고
    • 100 dietary oleic acid protects against the development of ulcerative colitis - A UK prospective cohort study using data from food Diaries
    • de Silva P.S., Luben R., Shrestha S.S., Welch A., Khaw K.-T., Hart A. 100 dietary oleic acid protects against the development of ulcerative colitis - A UK prospective cohort study using data from food Diaries. Gastroenterology 2010, 138:S-18.
    • (2010) Gastroenterology , vol.138
    • de Silva, P.S.1    Luben, R.2    Shrestha, S.S.3    Welch, A.4    Khaw, K.-T.5    Hart, A.6
  • 43
    • 42949150111 scopus 로고    scopus 로고
    • Dietary fatty acids differentially regulate production of TNF-[alpha] and IL-10 by Murine 3T3-L1 adipocytes
    • Bradley R.L., Fisher F.M., Maratos-Flier E. Dietary fatty acids differentially regulate production of TNF-[alpha] and IL-10 by Murine 3T3-L1 adipocytes. Obesity 2008, 16:938-944.
    • (2008) Obesity , vol.16 , pp. 938-944
    • Bradley, R.L.1    Fisher, F.M.2    Maratos-Flier, E.3
  • 44
    • 58149310977 scopus 로고    scopus 로고
    • Fatty acid-induced induction of Toll-like receptor-4/nuclear factor-kappaB pathway in adipocytes links nutritional signalling with innate immunity
    • Schaeffler A., Gross P., Buettner R., Bollheimer C., Buechler C., Neumeier M., et al. Fatty acid-induced induction of Toll-like receptor-4/nuclear factor-kappaB pathway in adipocytes links nutritional signalling with innate immunity. Immunology 2009, 126:233-245.
    • (2009) Immunology , vol.126 , pp. 233-245
    • Schaeffler, A.1    Gross, P.2    Buettner, R.3    Bollheimer, C.4    Buechler, C.5    Neumeier, M.6
  • 45
    • 33845306274 scopus 로고    scopus 로고
    • Proteasome-mediated degradation of IkappaBalpha and processing of p105 in Crohn disease and ulcerative colitis
    • Visekruna A., Joeris T., Seidel D., Kroesen A., Loddenkemper C., Zeitz M., et al. Proteasome-mediated degradation of IkappaBalpha and processing of p105 in Crohn disease and ulcerative colitis. J Clin Invest 2006, 116:3195-3203.
    • (2006) J Clin Invest , vol.116 , pp. 3195-3203
    • Visekruna, A.1    Joeris, T.2    Seidel, D.3    Kroesen, A.4    Loddenkemper, C.5    Zeitz, M.6
  • 46
    • 19344376504 scopus 로고    scopus 로고
    • Downregulation of ubiquitin-dependent protein degradation in murine myotubes during hyperthermia by eicosapentaenoic acid
    • Smith H.J., Khal J., Tisdale M.J. Downregulation of ubiquitin-dependent protein degradation in murine myotubes during hyperthermia by eicosapentaenoic acid. Biochem Biophysical Res Commun 2005, 332:83-88.
    • (2005) Biochem Biophysical Res Commun , vol.332 , pp. 83-88
    • Smith, H.J.1    Khal, J.2    Tisdale, M.J.3
  • 47
    • 0034817082 scopus 로고    scopus 로고
    • Downregulation of ubiquitin-dependent proteolysis by eicosapentaenoic acid in acute starvation
    • Whitehouse A.S., Tisdale M.J. Downregulation of ubiquitin-dependent proteolysis by eicosapentaenoic acid in acute starvation. Biochem Biophys Res Commun 2001, 285:598-602.
    • (2001) Biochem Biophys Res Commun , vol.285 , pp. 598-602
    • Whitehouse, A.S.1    Tisdale, M.J.2
  • 48
    • 77951274654 scopus 로고    scopus 로고
    • Dietary n-3 polyunsaturated fatty acids and the aetiology of ulcerative colitis: a UK prospective cohort study
    • John S., Luben R., Shrestha S.S., Welch A., Khaw K.T., Hart A.R. Dietary n-3 polyunsaturated fatty acids and the aetiology of ulcerative colitis: a UK prospective cohort study. Eur J Gastroenterol Hepatol 2010, 22:602-606.
    • (2010) Eur J Gastroenterol Hepatol , vol.22 , pp. 602-606
    • John, S.1    Luben, R.2    Shrestha, S.S.3    Welch, A.4    Khaw, K.T.5    Hart, A.R.6


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