Ursolic acid inhibits cigarette smoke extract-induced human bronchial epithelial cell injury and prevents development of lung cancer

Molecules

Volumn 17, Issue 8, 2012, Pages 9104-9115

  Liu, Wenbo ^a,b   Tan, Xiaobin ^a   Shu, Luan ^a   Sun, Hanyan ^b   Song, Jie ^a   Jin, Ping ^a   Yu, Siming ^b   Sun, Min ^b   Jia, Xiaobin ^a  

^a KEY LABORATORY OF NEW DRUG DELIVERY SYSTEM OF CHINESE MATERIA MEDICA   (China)

^b ANHUI UNIVERSITY   (China)

Author keywords

Chemopreventive; CSE; Nrf2; Phase II detoxifying enzymes; Ursolic acid

Indexed keywords

ALKYLATING AGENT; ANTINEOPLASTIC AGENT; CYCLOPHOSPHAMIDE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; LACTATE DEHYDROGENASE; NFE2L2 PROTEIN, HUMAN; NQO1 PROTEIN, HUMAN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); TRANSCRIPTION FACTOR NRF2; TRITERPENE; URSOLIC ACID;

ANIMAL; ARTICLE; BRONCHIOLE; CELL CULTURE; CELL PROLIFERATION; CELL PROTECTION; CELL SHAPE; CELL SURVIVAL; CELL TRANSFORMATION; CHEMOPROPHYLAXIS; DNA DAMAGE; DRUG DETOXIFICATION; DRUG EFFECT; DRUG SCREENING; ENZYMOLOGY; EPITHELIUM CELL; HUMAN; LUNG TUMOR; METABOLISM; MOUSE; NUDE MOUSE; PATHOLOGY; SMOKE; TOBACCO; TUMOR VOLUME;

ANIMALS; ANTICARCINOGENIC AGENTS; ANTINEOPLASTIC AGENTS, ALKYLATING; BRONCHIOLES; CELL PROLIFERATION; CELL SHAPE; CELL SURVIVAL; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; CHEMOPREVENTION; CYCLOPHOSPHAMIDE; CYTOPROTECTION; DNA DAMAGE; EPITHELIAL CELLS; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HUMANS; L-LACTATE DEHYDROGENASE; LUNG NEOPLASMS; METABOLIC DETOXICATION, PHASE II; MICE; MICE, NUDE; NAD(P)H DEHYDROGENASE (QUINONE); NF-E2-RELATED FACTOR 2; SMOKE; TOBACCO; TRITERPENES; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84865510287     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules17089104     Document Type: Article

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