Identification of two polysaccharides from Prunella vulgaris L. and evaluation on their anti-lung adenocarcinoma activity

Molecules

Volumn 15, Issue 8, 2010, Pages 5093-5103

  Feng, Liang ^a,b   Jia, Xiao Bin ^a   Shi, Feng ^a   Chen, Yan ^a  

^a KEY LABORATORY OF NEW DRUG DELIVERY SYSTEM OF CHINESE MATERIA MEDICA   (China)

^b MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Macao)

Author keywords

Anti lung adenocarcinoma; GC; Immune function; Polysaccharide; Prunella vulgaris L.

Indexed keywords

EID: 77956127736     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules15085093     Document Type: Article

References (16)

1. Tutin, T.G.; Burges, N.A.; Chater, A.O.; Edmondson, J.R.; Heywood, V.H.; Moore, D.M.; Valentine, D.H.; Walters, S.M.; Webb, D.A. Flora Europaea; Cambridge UniversityPress,:Cambridge, UK, 1993; Volume 1-5.
2. Jitka, P.; Milan, K.; Jaromír, S.; Zdenek, S.; Jaroslav, V.; Jitka, U. Biological Activities of Prunella vulgaris Extract. Phytother. Res. 2003, 17, 1082-1087.
3. Feng, L.; Chen, Y.; Jia, X.B.; Tan, X.B.; Gao, C.L.; Liu, G.M.; Shao, Z.Z. Evaluation of hierarchical cluster on fingerprint characteristic of Prunella species. China J. Trad. Chin. Med. Pharm. 2009, 9, 1216-1219.
4. Han, E.H.; Choi, J.H.; Hwang, Y.P.; Park, H.J.; Choi, C.Y.; Chung, Y.C.; Seo, J.K.; Jeong, H.G. Immunostimulatory activity of aqueous extract isolated from Prunella vulgaris. Food Chem. Toxicol. 2009, 47, 62-69.
5. Harput, U.S.; Saracoglu, I.; Ogihara, Y. Effects of Two Prunella Species on Lymphocyte Pliferation and Nitric Oxide Production. Phytother. Res. 2006, 20, 157-159.
6. Fang, X.;Yu, M.M.;Yuen, W.H.; Zee, S.Y.; Chang, R.C. Immune modulatory effects of Prunella vulgaris L. on monocytes/macrophages. Int. J. Mol. Med. 2005, 16, 1109-1116.
7. Fang, X.; Chang, R.C.; Yuen, W.H.; Zee, S.Y. Immune modulatory effects of Prunella vulgaris L. Int. J. Mol. Med. 2005, 15, 491-496.
8. Tabba, H.D.; Chang, R.S.; Smith, K.M. Isolation, purification, and partial characterization of prunellin, an anti-HIV component from aqueous extracts of Prunella vulgaris. Antivir. Res. 1989, 11, 263-273.
9. Zhang, D.H. Isolation, Purification and Antioxidant Activity of the Polysaccharide of Prunella vugaris(Labiatae). Acta Botaniea Yunnaniea 2006, 28, 410-414.
10. Chen, Y.; Xie, M.Y.; Wang, Y.X.; Nie, S.P.; Li, C. Analysis of the monosaccharide composition ofpurified polysaccharides in Ganoderma atrum by capillary gas chromatography. Phytochem. Anal. 2009, 20, 503-510.
11. Zhang, Y.; Yu, Y.; Zhang, H. Analysis of monosaccharides in Radix Rehmanniae by GC. Zhongguo Zhong Yao Za Zhi 2009, 34, 419-422.
12. Xu, D.J.; Xia, Q.; Wang, J.J.; Wang, P.P. Molecular Weight and Monosaccharide Composition of Astragalus Polysaccharides. Molecules 2008, 13, 2408-2415.
13. Liu, F.; Zhu, X.H.; Liu, M.; Zhou, J.; Che, X.P.; Han, R.F. Study on deproteinization anddecoloration in extraction of polysaccharides from Rabdosia rubescens. Zhong Yao Cai 2008, 31,751-753.
14. Jiang, L.H.; Feng,Y.;Shen, L.; Xu, D.S. Research on method in avoiding the interference of poloxamer in determination of polysaccharides in thermosensitive gel. Zhong Yao Cai 2007, 30, 1443-1446.
15. Gao, Z.; Zhang, D.; Guo, C. Paclitaxel Efficacy is Increased by Parthenolide via Nuclear Factor-KappaB Pathways in In Vitro and In Vivo Human Non-Small Cell Lung Cancer Models. Curr. Cancer Drug Targets 2010, in press.
16. Choi, J.H.; Han, E.H.; Hwang, Y.P.; Choi, J.M.; Choi, C.Y.; Chung, Y.C.; Seo, J.K.; Jeong, H.G. Suppression of PMA-induced tumor cell invasion and metastasis by aqueous extract isolated from Prunella vulgaris via the inhibition of NF-κB-dependent MMP-9 expression. Food Chem. Toxicol. 2010, 48, 564-571.