Suppression of nuclear factor-κB activation and inflammation in microglia by physically modified saline

Journal of Biological Chemistry

Volumn 287, Issue 35, 2012, Pages 29529-29542

  Khasnavis, Saurabh ^a   Jana, Arundhati ^a   Roy, Avik ^a   Mazumder, Monalisa ^b   Bhushan, Bharat ^b   Wood, Tony ^c   Ghosh, Supurna ^c   Watson, Richard ^c   Pahan, Kalipada ^a  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c Revalesio Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-INFLAMMATORIES; ANTI-INFLAMMATORY EFFECTS; CAMP-RESPONSE ELEMENT-BINDING PROTEINS; CHEMICAL INHIBITORS; CHRONIC INFLAMMATION; DOMINANT-NEGATIVE MUTANTS; ELEVATED OXYGEN PRESSURE; ENDOGENOUS INHIBITOR; EXCESS OXYGEN; GLIAL CELLS; HUMAN DISEASE; MICROGLIA; NEURODEGENERATIVE DISORDERS; NUCLEAR FACTORS; PHOSPHATIDYLINOSITOL; PROINFLAMMATORY MOLECULES; SALINE SOLUTIONS; SYNTHASES; TCP MODIFICATION; THERAPEUTIC BENEFITS; UP-REGULATION;

ENZYMES; NEURODEGENERATIVE DISEASES; NITRIC OXIDE; OXYGEN; TRANSCRIPTION FACTORS;

PATHOLOGY;

ANTIINFLAMMATORY AGENT; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RNS 60; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ACTIVATION; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; FLOW KINETICS; GLIA CELL; INTRACELLULAR SIGNALING; MICROGLIA; MOUSE; NERVOUS SYSTEM INFLAMMATION; NEUROPATHOLOGY; NONHUMAN; OXYGEN TENSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ANIMALS; CELL LINE; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; I-KAPPA B PROTEINS; INFLAMMATION; MICE; MICROGLIA; NERVE TISSUE PROTEINS; NEURODEGENERATIVE DISEASES; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OXYGEN; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SODIUM CHLORIDE;

EID: 84865489968     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.338012     Document Type: Article

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