Negative-pressure cavitation extraction of four main vinca alkaloids from Catharanthus roseus leaves

Molecules

Volumn 17, Issue 8, 2012, Pages 8742-8752

  Mu, Fansong ^a,b   Yang, Liuqing ^a,b   Wang, Wei ^a,b   Luo, Meng ^a,b,c   Fu, Yujie ^a,b   Guo, Xiaorui ^a,b   Zu, Yuangang ^a,b  

^a NORTHEAST FORESTRY UNIVERSITY   (China)

^b State Engineering Laboratory of Bio Resource Eco Utilization   (China)

^c Zhejiang Hisun Pharmaceutical Co Ltd   (China)

Author keywords

Catharanthus roseus; Negative pressure cavitation extraction; Vinca alkaloids

Indexed keywords

ALCOHOL; CATHARANTHINE; DRUG DERIVATIVE; PLANT EXTRACT; SOLVENT; TUBULIN MODULATOR; VINBLASTINE; VINCA ALKALOID; VINCRISTINE; VINDOLINE;

ARTICLE; CATHARANTHUS; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION AND PURIFICATION; PARTICLE SIZE; PLANT LEAF; REVERSED PHASE LIQUID CHROMATOGRAPHY; SOLID PHASE EXTRACTION; VACUUM;

CATHARANTHUS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, REVERSE-PHASE; ETHANOL; PARTICLE SIZE; PLANT EXTRACTS; PLANT LEAVES; SOLID PHASE EXTRACTION; SOLVENTS; TUBULIN MODULATORS; VACUUM; VINBLASTINE; VINCA ALKALOIDS; VINCRISTINE;

EID: 84865471809     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules17088742     Document Type: Article

References (25)

1. Noble, R.L. The discovery of the vinca alkaloids-chemotherapeutic agents against cancer. Biochem. Cell Biol. 1990, 68, 1344-1351.
2. Zu, Y.G.; Luo, M.; Mu, F.S.; Fu, Y.J.; Wang, L. Advances on alkaloids in Catharanthus roseus and their pharmacological activities. Nat. Prod. Res. Dev. 2006, 18, 325-329.
3. Van der Heijden, R.; Jacobs, D.I.; Snoeijer, W.; Hallard, D.; Verpoorte, R. The Catharanthus alkaloids: pharmacognosy and biotechnology. Curr. Med. Chem. 2004, 5, 607-628.
4. Sertel, S.; Zu, Y.G.; Fu, Y.J.; Rebacz, B.; Kon-kimalla, B.; Plinkert, P.K.; Krämer, A.; Gertsch, J.; Efferth, T. Molecular docking and pharmacogenomics of vinca alkaloids and their monomeric precursors, vindoline and catharanthine. Biochem. Pharm. 2011, 81, 723-735.
5. Armstrong, J.G.; Dyke, R.W.; Fouts, P.J. Vinblastine sulfate treatment of hodgkin's disease during a pregnancy. Science 1964, 143, 703.
6. Evans, A.E.; Farber, S.; Brunet, S.; Mariano, P.J. Vincristine in the treatment of acute leukemia in children. Cancer 1963, 16, 1302-1306.
7. Jordan, M.A.; Wilson, L. Microtubules as a target for anticancer drugs. Nat. Rev. Cancer 2004, 4, 253-265.
8. Zu, Y.G.; Fu, Y.J.; Luo, M.; Mu, F.S. Structure modification for reduced toxicity derivatives and anticancer activity of vinblastine (in Chinese). Chem. Online 2004, 67, w027.
9. Renault, J.H.; Nuzillard, J.M.; Le Crouérour, G.; Thépenier, P.; Zèches-Hanrot, M.; Le Men-Olivier, L. Isolation of indole alkaloids from Catharanthus roseus by centrifugal partition chromatography in the pH-zone refining mode. J. Chromatogr. A 1999, 849, 421-431.
10. Choi, Y.H.; Yoo, K.P.; Kim, J. Supercritical fluid extraction and liquid chromatography-electrospray mass analysis of vinblastine from Catharanthus roseus. Chem. Pharm. Bull. 2002, 50, 1294-1296.
11. Zu, Y.G.; Luo, M.; Mu, F.S.; Fu, Y.J. Research on ultrasound-assisted extraction process of vinblastine from Catharanthus roseus. Chin. Trad. Herbal Drugs 2007, 38, 1348-1349.
12. Verma, A.; Laakso, I.; Seppänen-Laakso, T.; Huhtikangas, A.; Riekkola, M.L. A simplified procedure for indole alkaloid extraction from Catharanthus roseus combined with a semi-synthetic production process for vinblastine. Molecules 2007, 12, 1307-1315.
13. Mu, F.S.; Luo, M.; Fu, Y.J.; Tian, H.; Zu, Y.G. Optimization of microwave assisted extraction process of vinblastine by orthogonalmethod. Chem. Eng. 2008, 36, 62-65.
14. Li, S.M.; Fu, Y.J.; Zu, Y.G.; Zu, B.S.; Wang, Y.; Efferth, T. Determination of paclitaxel and its analogues in the needles of Taxus species by using negative pressure cavitation extraction followed by HPLC-MS-MS. J. Sep. Sci. 2009, 32, 3958-3966.
15. Zhang, D.Y.; Zu, Y.G.; Fu, Y.J.; Luo, M.; Gu, C.B.; Wang, W.; Yao, X.H. Negative pressure cavitation extraction and antioxidant activity of biochanin A and genistein from the leaves of Dalbergia odorifera T. Chen. Sep. Purif. Technol. 2011, 83, 91-99.
16. Zhao, B.S.; Fu, Y.J.; Wang, W.; Zu, Y.G.; Gu, C.B.; Luo, M.; Efferth, T. Enhanced extraction of isoflavonoids from Radix Astragali by incubation pretreatment combined with negative pressure cavitation and its antioxidant activity. Innovat. Food Sci. Emerg. Tech. 2011, 12, 577-585.
17. Dong, L.L.; Fu, Y.J.; Zu, Y.G.; Li, J.; Li, X.J.; Efferth, T. Negative pressure cavitation accelerated processing for extraction of main bioactive flavonoids from Radix Scutellariae. Chem. Eng. Process. 2011, 50, 780-789.
18. Zhang, D.Y.; Zu, Y.G.; Fu, Y.J.; Luo, M.; Wang, W.; Gu, C.B.; Zhao, C.J.; Jiao, J.; Efferth, T. Enzyme pretreatment and negative pressure cavitation extraction of genistein and apigenin from the roots of pigeon pea [Cajanus cajan (L.) Millsp.] and the evaluation of antioxidant activity. Ind. Crop. Prod. 2012, 37, 311-320.
19. Wang, W.; Li, N.; Luo, M.; Zu, Y.; Efferth, T. Antibacterial activity and anticancer activity of Rosmarinus officinalis L. essential oil compared to that of its main components. Molecules 2012, 17, 2704-2713.
20. Liu, W.; Fu, Y.J.; Zu, Y.G.; Kong, Y.; Zhang, L.; Zu, B.S.; Efferth, T. Negative-pressure cavitation extraction for the determination of flavonoids in pigeon pea leaves by liquid chromatography-tandem mass spectrometry. J. Chromatogr. A 2009, 1216, 3841-3850.
21. Zhang, D.Y.; Zhang, S.; Zu, Y.G.; Fu, Y.J.; Kong, Y.; Gao, Y.; Zhao, J.T.; Efferth, T. Negative pressure cavitation extraction and antioxidant activity of genistein and genistin from the roots of pigeon pea [Cajanus cajan (L.) Millsp.]. Sep. Purif. Technol. 2010, 74, 261-270.
22. Kong, Y.; Wei, Z.F.; Fu, Y.J.; Gu, C.B.; Zhao, C.J.; Yao, X.H.; Efferth, T. Negative-pressure cavitation extraction of cajaninstilbene acid and pinostrobin from pigeon pea [Cajanus cajan (L.) Millsp.] leaves and evaluation of antioxidant activity. Food Chem. 2011, 128, 596-605.
23. Dong, L.L.; Fu, Y.J.; Zu, Y.G.; Luo, M.; Wang, W.; Li, X.J.; Li, J. Application of cavitation system to accelerate the endogenous enzymatic hydrolysis of baicalin and wogonoside in Radix Scutellariae. Food Chem. 2012, 131, 1422-1429.
24. Hisiger, S.; Jolicoeur, M. Analysis of Catharanthus roseus alkaloids by HPLC. Phytochem. Rev. 2007, 6, 207-234.
25. Luo, M.; Fu, Y.J.; Zu, Y.G.; Shi, Q.; Mu, F.S.; Li, Q.Y. Rapid determination of 4 vinca alkaloids by reversed phase high performance liquid chromatography. Chin. J. Anal. Chem. 2005, 33, 87-89.