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Volumn 90, Issue 9, 2012, Pages 1235-1245

Up-regulation of myocardial connexin-43 in spontaneously hypertensive rats fed red palm oil is most likely implicated in its anti-arrhythmic effects

Author keywords

Arrhythmias; Connexin 43; Heart; Pkc ; Red palm oil; Shr

Indexed keywords

CONNEXIN 43; MESSENGER RNA; PALM OIL; PROTEIN KINASE C EPSILON; RED PALM OIL; UNCLASSIFIED DRUG;

EID: 84865438875     PISSN: 00084212     EISSN: 12057541     Source Type: Journal    
DOI: 10.1139/Y2012-103     Document Type: Article
Times cited : (19)

References (46)
  • 1
    • 79251485992 scopus 로고    scopus 로고
    • Omega-3 fatty acids and atorvastatin suppress ventricular fibrillation inducibility in hypertrigly-ceri-demic rat hearts: Implication of intracellular coupling protein, connexin-43
    • PMID: 21224503
    • Bacova, B., Radošinská, J., Knezl, V., Kolenova, L., Weismann, P., Navarova, J., et al. 2010. Omega-3 fatty acids and atorvastatin suppress ventricular fibrillation inducibility in hypertrigly-ceri-demic rat hearts: implication of intracellular coupling protein, connexin-43. J. Physiol. Pharmacol. 61(6): 717-723.PMID: 21224503.
    • (2010) J. Physiol. Pharmacol , vol.61 , Issue.6 , pp. 717-723
    • Bacova, B.1    Radošinská, J.2    Knezl, V.3    Kolenova, L.4    Weismann, P.5    Navarova, J.6
  • 2
    • 20444399144 scopus 로고    scopus 로고
    • Cancer prevention by retinoids and carotenoids: Independent action on a common target
    • PMID:15949684
    • Bertram, J.S., and Vine, A.L. 2005. Cancer prevention by retinoids and carotenoids: Independent action on a common target. Biochim. Biophys. Acta, 1740(2): 170-178.PMID:15949684.
    • (2005) Biochim. Biophys. Acta , vol.1740 , Issue.2 , pp. 170-178
    • Bertram, J.S.1    Vine, A.L.2
  • 3
    • 77953630667 scopus 로고    scopus 로고
    • Dietary red palm oil supplementation reduces myocardial infarct size in an isolated perfused rat heart model
    • doi:10.1186/1476-511X-9-64.PMID:20565865
    • Bester, D.J., Kupai, K., Csont, T., Szucs, G., Csonka, C., Esterhuyse, A.J., et al. 2010. Dietary red palm oil supplementation reduces myocardial infarct size in an isolated perfused rat heart model. Lipids Health Dis. 9(64): 1-7. doi:10.1186/1476-511X-9-64.PMID:20565865.
    • (2010) Lipids Health Dis , vol.9 , Issue.64 , pp. 1-7
    • Bester, D.J.1    Kupai, K.2    Csont, T.3    Szucs, G.4    Csonka, C.5    Esterhuyse, A.J.6
  • 4
    • 20444377656 scopus 로고    scopus 로고
    • Connexins and their environment: Effects of lipids composition on ion channels
    • doi:10.1016/j.bbamem.2004.12.001.PMID:15955299
    • Cascio, M. 2005. Connexins and their environment: effects of lipids composition on ion channels. Biochim. Biophys. Acta, 1711(2): 142-153. doi:10.1016/j.bbamem.2004.12.001.PMID:15955299.
    • (2005) Biochim. Biophys. Acta , vol.1711 , Issue.2 , pp. 142-153
    • Cascio, M.1
  • 5
    • 39149121499 scopus 로고    scopus 로고
    • Cardioprotection with palm oil tocotrienols: Comparision of different isomers
    • doi:10.1152/ajpheart.01200.2007.PMID:18083895
    • Das, S., Lekli, I., Das, M., Szabo, G., Varadi, J., Juhasz, B., et al. 2008. Cardioprotection with palm oil tocotrienols: comparision of different isomers. Am. J. Physiol. Heart Circ. Physiol. 294(2): H970-H978. doi:10.1152/ajpheart.01200.2007.PMID:18083895.
    • (2008) Am. J. Physiol. Heart Circ. Physiol , vol.294 , Issue.2
    • Das, S.1    Lekli, I.2    Das, M.3    Szabo, G.4    Varadi, J.5    Juhasz, B.6
  • 6
    • 0032103164 scopus 로고    scopus 로고
    • Gap junctional channels in cardiovascular system: Pharmacological and physiological modulation
    • doi:10.1016/S0165-6147(98)01192-4.PMID:9666714
    • Dhein, S. 1998. Gap junctional channels in cardiovascular system: pharmacological and physiological modulation. Trends Pharmacol. Sci. 19(6): 229-241. doi:10.1016/S0165-6147(98)01192-4.PMID:9666714.
    • (1998) Trends Pharmacol. Sci , vol.19 , Issue.6 , pp. 229-241
    • Dhein, S.1
  • 7
    • 0034975483 scopus 로고    scopus 로고
    • Altered connexin expression in human congestive heart failure
    • doi:10.1006/jmcc.2000.1308.PMID:11162139
    • Dupont, E., Matsushita, T., Kaba, R.A., Vozzi, C., Coppen, S.R., Khan, N., et al. 2001. Altered connexin expression in human congestive heart failure. J. Mol. Cell. Cardiol. 33(2): 359-371. doi:10.1006/jmcc.2000.1308.PMID:11162139.
    • (2001) J. Mol. Cell. Cardiol , vol.33 , Issue.2 , pp. 359-371
    • Dupont, E.1    Matsushita, T.2    Kaba, R.A.3    Vozzi, C.4    Coppen, S.R.5    Khan, N.6
  • 8
    • 0036770253 scopus 로고    scopus 로고
    • Palm oil: Biochemical, physiological, nutritional, hematological, and toxicological aspects: A review
    • doi:10.1023/A:1021828132707.PMID:12602939
    • Edem, D.O. 2002. Palm oil: biochemical, physiological, nutritional, hematological, and toxicological aspects: a review. Plant Foods Hum. Nutr. 57(3-4): 319-341. doi:10.1023/A:1021828132707.PMID:12602939.
    • (2002) Plant Foods Hum. Nutr , vol.57 , Issue.3-4 , pp. 319-341
    • Edem, D.O.1
  • 9
    • 33645087656 scopus 로고    scopus 로고
    • p38- MAPK and PKB/Akt, possible role players in red palm oil-induced protection of the isolated perfused rat heart
    • doi:10.1016/j.jnutbio. 2005.05.001.PMID:16229999
    • Engelbrecht, A.M., Esterhuyse, A.J., Du Toit, E.F., Lochner, A., and van Rooyen, J. 2006. p38- MAPK and PKB/Akt, possible role players in red palm oil-induced protection of the isolated perfused rat heart. J. Nutr. Biochem. 17(4): 265-271. doi:10.1016/j.jnutbio. 2005.05.001.PMID:16229999.
    • (2006) J. Nutr. Biochem , vol.17 , Issue.4 , pp. 265-271
    • Engelbrecht, A.M.1    Esterhuyse, A.J.2    du Toit, E.F.3    Lochner, A.4    van Rooyen, J.5
  • 10
    • 68149181874 scopus 로고    scopus 로고
    • The effect of dietary red palm oil on the functional recovery of the ischaemic/reperfused rat heart: The involvement of the PI3-kinase signalling pathway
    • PMID:19128464
    • Engelbrecht, A.-M., Odendaal, L., Du Toit, E.F., Kupai, K., Csont, T., Ferdinandy, P., et al. 2009. The effect of dietary red palm oil on the functional recovery of the ischaemic/reperfused rat heart: the involvement of the PI3-kinase signalling pathway. Lipids Health Dis. 8(18): 1-8.PMID:19128464.
    • (2009) Lipids Health Dis , vol.8 , Issue.18 , pp. 1-8
    • Engelbrecht, A.-M.1    Odendaal, L.2    du Toit, E.F.3    Kupai, K.4    Csont, T.5    Ferdinandy, P.6
  • 11
    • 12344279099 scopus 로고    scopus 로고
    • Dietary red palm oil improves reperfusion cardiac function in the isolated perfused rat heart of animals fed a high cholesterol diet
    • doi:10.1016/j.plefa.2004.10.014.PMID:15664299
    • Esterhuyse, A.J., Du Toit, E.F., Benade, A.J.S., and van Rooyen, J. 2005. Dietary red palm oil improves reperfusion cardiac function in the isolated perfused rat heart of animals fed a high cholesterol diet. Prostaglandins Leukot. Essent. Fatty Acids, 72(3): 153-161. doi:10.1016/j.plefa.2004.10.014.PMID:15664299.
    • (2005) Prostaglandins Leukot. Essent. Fatty Acids , vol.72 , Issue.3 , pp. 153-161
    • Esterhuyse, A.J.1    du Toit, E.F.2    Benade, A.J.S.3    van Rooyen, J.4
  • 12
    • 33750479343 scopus 로고    scopus 로고
    • Proposed mechanisms for red palm oil induced cardioprotection in a model of hyperlipidaemia in the rat
    • doi:10.1016/j.plefa.2006.07.001.PMID:16920346
    • Esterhuyse, J.S., van Rooyen, J., Strijdom, H., Bester, D., and Du Toit, E.F. 2006. Proposed mechanisms for red palm oil induced cardioprotection in a model of hyperlipidaemia in the rat. Prostaglandins Leukot. Essent. Fatty Acids, 75(6): 375-384. doi:10.1016/j.plefa.2006.07.001.PMID:16920346.
    • (2006) Prostaglandins Leukot. Essent. Fatty Acids , vol.75 , Issue.6 , pp. 375-384
    • Esterhuyse, J.S.1    van Rooyen, J.2    Strijdom, H.3    Bester, D.4    du Toit, E.F.5
  • 13
    • 48749131471 scopus 로고    scopus 로고
    • Prehypertension-role of drug therapy
    • PMID:19212015
    • Fischer, L., Puri, A., and Saran, R.K. 2008. Prehypertension-role of drug therapy. Indian Heart J. 60(1): 5-8.PMID:19212015.
    • (2008) Indian Heart J , vol.60 , Issue.1 , pp. 5-8
    • Fischer, L.1    Puri, A.2    Saran, R.K.3
  • 14
    • 34548235903 scopus 로고    scopus 로고
    • Protein kinase C3 mediates salutary effects on electrical coupling induced by ischemic preconditioning
    • doi:10.1016/j.hrthm.2007.05.030.PMID:17765619
    • Hund, T.J., Lerner, D.L., Yamada, K.A., Schuessler, R.B., and Saffitz, J.E. 2007. Protein kinase C3 mediates salutary effects on electrical coupling induced by ischemic preconditioning. Heart Rhythm, 4(9): 1183-1193. doi:10.1016/j.hrthm.2007.05.030.PMID:17765619.
    • (2007) Heart Rhythm , vol.4 , Issue.9 , pp. 1183-1193
    • Hund, T.J.1    Lerner, D.L.2    Yamada, K.A.3    Schuessler, R.B.4    Saffitz, J.E.5
  • 15
    • 0003633755 scopus 로고    scopus 로고
    • ILAR (Institute of Laboratory Animal Resources), NIH Publication No. 85-23 (revised 1996). National Academy Press, Washington, D.C
    • ILAR (Institute of Laboratory Animal Resources). 1996. Guide for the Care and Use of Laboratory Animals. NIH Publication No. 85-23 (revised 1996). National Academy Press, Washington, D.C. Available from www.nap.edu/openbook.php?record_id=5140.
    • (1996) Guide For the Care and Use of Laboratory Animals
  • 16
    • 45849091842 scopus 로고    scopus 로고
    • Pharmacological inhibition of epsilon-protein kinase C attenuates cardiac fibrosis and dysfunction in hypertension-induced heart failure
    • doi:10. 1161/HYPERTENSIONAHA.107.109637.PMID:18413490
    • Inagaki, K., Koyanagi, T., Berry, N.C., Sun, L., and Mochly-Rosen, D. 2008. Pharmacological inhibition of epsilon-protein kinase C attenuates cardiac fibrosis and dysfunction in hypertension-induced heart failure. Hypertension, 51(6): 1565-1569. doi:10. 1161/HYPERTENSIONAHA.107.109637.PMID:18413490.
    • (2008) Hypertension , vol.51 , Issue.6 , pp. 1565-1569
    • Inagaki, K.1    Koyanagi, T.2    Berry, N.C.3    Sun, L.4    Mochly-Rosen, D.5
  • 17
    • 0024849696 scopus 로고
    • Oxidative injury to myocardial membrane: Direct modulation by endogenous alpha-tocopherol
    • doi:10.1016/0022-2828 (89)90689-5.PMID:2558223
    • Janero, D.R., and Burghardt, B. 1989. Oxidative injury to myocardial membrane: direct modulation by endogenous alpha-tocopherol. J. Mol. Cell. Cardiol. 21(11): 1111-1124. doi:10.1016/0022-2828 (89)90689-5.PMID:2558223.
    • (1989) J. Mol. Cell. Cardiol , vol.21 , Issue.11 , pp. 1111-1124
    • Janero, D.R.1    Burghardt, B.2
  • 18
    • 84861582126 scopus 로고    scopus 로고
    • Connexin43 phosphorylation and cytoprotection in the heart
    • doi:10.1016/ j.bbamem.2011.06.023.PMID:21763271
    • Jeyaraman, M.M., Srisakuldee, W., Nickel, B.E., and Kardami, E. 2012. Connexin43 phosphorylation and cytoprotection in the heart. Biochim. Biophys. Acta, 1818(8): 2009-2013. doi:10.1016/ j.bbamem.2011.06.023.PMID:21763271.
    • (2012) Biochim. Biophys. Acta , vol.1818 , Issue.8 , pp. 2009-2013
    • Jeyaraman, M.M.1    Srisakuldee, W.2    Nickel, B.E.3    Kardami, E.4
  • 19
    • 0037286470 scopus 로고    scopus 로고
    • Gap junction remodeling and altered connexin43 expression in the failing human heart
    • doi:10.1023/A:1021154115673.PMID:12619876
    • Kostin, S., Rieger, M., Dammer, S., Hein, S., Richter, M., Klovekorn, W.P., et al. 2003. Gap junction remodeling and altered connexin43 expression in the failing human heart. Mol. Cell. Biochem. 242(1-2): 135-144. doi:10.1023/A:1021154115673.PMID:12619876.
    • (2003) Mol. Cell. Biochem , vol.242 , Issue.1-2 , pp. 135-144
    • Kostin, S.1    Rieger, M.2    Dammer, S.3    Hein, S.4    Richter, M.5    Klovekorn, W.P.6
  • 20
    • 1942534677 scopus 로고    scopus 로고
    • Connexin 43 expression and distribution in compensated and decompensated cardiac hypertrophy in patients with aortic stenosis
    • doi:10. 1016/j.cardiores.2003.12.010.PMID:15094362
    • Kostin, S., Dammer, S., Hein, S., Klovekorn, W.P., Bauer, E.P., and Schaper, J. 2004. Connexin 43 expression and distribution in compensated and decompensated cardiac hypertrophy in patients with aortic stenosis. Cardiovasc. Res. 62(2): 426-436. doi:10. 1016/j.cardiores.2003.12.010.PMID:15094362.
    • (2004) Cardiovasc. Res , vol.62 , Issue.2 , pp. 426-436
    • Kostin, S.1    Dammer, S.2    Hein, S.3    Klovekorn, W.P.4    Bauer, E.P.5    Schaper, J.6
  • 21
    • 33947496996 scopus 로고    scopus 로고
    • Dietary red palm oil reduces ischaemia- reperfusion injury in rats fed a hypercholesterolaemic diet
    • doi:10.1017/S0007114507658991.PMID: 17349
    • Kruger, M.J., Engelbrecht, A.M., Esterhuyse, J., Du Toit, E.F., and van Rooyen, J. 2007. Dietary red palm oil reduces ischaemia- reperfusion injury in rats fed a hypercholesterolaemic diet. Br. J. Nutr. 97(4): 653-660. doi:10.1017/S0007114507658991.PMID: 17349077.
    • (2007) Br. J. Nutr , vol.97 , Issue.4 , pp. 653-660
    • Kruger, M.J.1    Engelbrecht, A.M.2    Esterhuyse, J.3    du Toit, E.F.4    van Rooyen, J.5
  • 22
    • 46849102162 scopus 로고    scopus 로고
    • Thyroid hormones suppress epsilon-PKC signalling, down-regulate connexin-43 and increase lethal arrhythmia susceptibility in non-diabetic and diabetic rat hearts
    • PMID:18622045
    • Lin, H., Mitasíková, M., Dlugosova, K., Okruhlicova, L., Imanaga, I., Ogawa, K., et al. 2008. Thyroid hormones suppress epsilon-PKC signalling, down-regulate connexin-43 and increase lethal arrhythmia susceptibility in non-diabetic and diabetic rat hearts. J. Physiol. Pharmacol. 59(2): 271-285.PMID:18622045.
    • (2008) J. Physiol. Pharmacol , vol.59 , Issue.2 , pp. 271-285
    • Lin, H.1    Mitasíková, M.2    Dlugosova, K.3    Okruhlicova, L.4    Imanaga, I.5    Ogawa, K.6
  • 23
    • 0036850724 scopus 로고    scopus 로고
    • The cardiac gap junction: A potential therapeutic target in the treatment of heart disease
    • Liu, F., and Gutstein, D.E. 2002. The cardiac gap junction: a potential therapeutic target in the treatment of heart disease. Mt. Sinai J. Med. 69(6): 421-424.PMID:12429963.
    • (2002) Mt. Sinai J. Med , vol.69 , Issue.6 , pp. 421-424
    • Liu, F.1    Gutstein, D.E.2
  • 24
    • 79957610506 scopus 로고    scopus 로고
    • Telmisartan, a unique ARB, improves left ventricular remodeling of infarcted heart by activating PPAR gamma
    • doi:10.1038/labinvest.2011.45.PMID:21403641
    • Maejima, Y., Okada, H., Haraguchi, G., Onai, Y., Kosuge, H., Suzuki, J., and Isobe, M. 2011. Telmisartan, a unique ARB, improves left ventricular remodeling of infarcted heart by activating PPAR gamma. Lab. Invest. 91(6): 932-944. doi:10.1038/labinvest.2011.45.PMID:21403641.
    • (2011) Lab. Invest , vol.91 , Issue.6 , pp. 932-944
    • Maejima, Y.1    Okada, H.2    Haraguchi, G.3    Onai, Y.4    Kosuge, H.5    Suzuki, J.6    Isobe, M.7
  • 25
    • 0037324289 scopus 로고    scopus 로고
    • Antidiabetic PPAR gamma-activator rosiglitazone reduces MMP-9 serum levels in type 2 diabetic patients with coronary artery disease
    • doi:10.1161/01.ATV.0000054195.35121.5E.PMID: 12588772
    • Marx, N., Froehlich, J., Siam, L., Ittner, J., Wierse, G., Schmidt, A., et al. 2003. Antidiabetic PPAR gamma-activator rosiglitazone reduces MMP-9 serum levels in type 2 diabetic patients with coronary artery disease. Arterioscler. Thromb. Vasc. Biol. 23(2): 283-288. doi:10.1161/01.ATV.0000054195.35121.5E.PMID: 12588772.
    • (2003) Arterioscler. Thromb. Vasc. Biol , vol.23 , Issue.2 , pp. 283-288
    • Marx, N.1    Froehlich, J.2    Siam, L.3    Ittner, J.4    Wierse, G.5    Schmidt, A.6
  • 26
    • 66349103649 scopus 로고    scopus 로고
    • Diabetes and thyroid hormones affect connexin-43 and PKC-3 expression in rat heart atria
    • PMID:18380541
    • Mitasíková, M., Lin, H., Soukup, T., Imanaga, I., and Tribulová, N. 2009. Diabetes and thyroid hormones affect connexin-43 and PKC-3 expression in rat heart atria. Physiol. Res. 58(2): 211-217.PMID:18380541.
    • (2009) Physiol. Res , vol.58 , Issue.2 , pp. 211-217
    • Mitasíková, M.1    Lin, H.2    Soukup, T.3    Imanaga, I.4    Tribulová, N.5
  • 27
    • 0030309827 scopus 로고    scopus 로고
    • Arterial pressure and lipid profile in rats following chronic ingestion of palm oil diets
    • PMID:9532303
    • Osim, E.E., Owu, D.U., and Etta, K.M. 1996. Arterial pressure and lipid profile in rats following chronic ingestion of palm oil diets. Afr. J. Med. Med. Sci. 25(4): 335-340.PMID:9532303.
    • (1996) Afr. J. Med. Med. Sci , vol.25 , Issue.4 , pp. 335-340
    • Osim, E.E.1    Owu, D.U.2    Etta, K.M.3
  • 28
    • 77955012886 scopus 로고    scopus 로고
    • Novel therapeutic targets for hypertension
    • doi:10.1038/ nrcardio.2010.85.PMID:20567239
    • Paulis, L., and Unger, T. 2010. Novel therapeutic targets for hypertension. Nat. Rev. Cardiol. 7(8): 431-441. doi:10.1038/ nrcardio.2010.85.PMID:20567239.
    • (2010) Nat. Rev. Cardiol , vol.7 , Issue.8 , pp. 431-441
    • Paulis, L.1    Unger, T.2
  • 29
    • 0032485875 scopus 로고    scopus 로고
    • Myocardial architecture and ventricular arrhythmogenesis
    • doi:10.1161/01.CIR.97.17.1746.PMID:9591770
    • Peters, N.S., and Wit, A.L. 1998. Myocardial architecture and ventricular arrhythmogenesis. Circulation, 97(17): 1746-1754. doi:10.1161/01.CIR.97.17.1746.PMID:9591770.
    • (1998) Circulation , vol.97 , Issue.17 , pp. 1746-1754
    • Peters, N.S.1    Wit, A.L.2
  • 30
    • 0037019966 scopus 로고    scopus 로고
    • c-Jun N-terminal kinase activation mediates downregulation of connexin43 in cardiomyocytes
    • doi:10.1161/01.RES.0000035854.11082.01.PMID: 12364393
    • Petrich, B.G., Gong, X., Lerner, D., Wang, X., Brown, J.H., Saffitz, J. E., et al. 2002. c-Jun N-terminal kinase activation mediates downregulation of connexin43 in cardiomyocytes. Circ. Res. 91 (7): 640-647. doi:10.1161/01.RES.0000035854.11082.01.PMID: 12364393.
    • (2002) Circ. Res , vol.91 , Issue.7 , pp. 640-647
    • Petrich, B.G.1    Gong, X.2    Lerner, D.3    Wang, X.4    Brown, J.H.5    Saffitz, J.E.6
  • 31
    • 84865404413 scopus 로고    scopus 로고
    • Spontaneously diabetic rats in pre-hyperten-sive stage benefit from omega-3 fatty acids supplementation
    • doi:10.1097/01.hjh.0000379067.15513.1c
    • Radošinská, J., Bacova, B., Dosenko, V., Lin, H., Imanaga, I., and Tribulová, N. 2010. Spontaneously diabetic rats in pre-hyperten-sive stage benefit from omega-3 fatty acids supplementation. J. Hypertens. 28: 292-293. doi:10.1097/01.hjh.0000379067.15513.1c.
    • (2010) J. Hypertens , vol.28 , pp. 292-293
    • Radošinská, J.1    Bacova, B.2    Dosenko, V.3    Lin, H.4    Imanaga, I.5    Tribulová, N.6
  • 32
    • 78651311624 scopus 로고    scopus 로고
    • Myocardial NOS activity and connexin-43 expression in untreated and omega-3 fatty acids-treated spontaneously hypertensive and hereditary hypertriglyceridemic rats
    • doi:10.1007/s11010-010-0625-0.PMID:20963625
    • Radošinská, J., Bacova, B., Bernatova, I., Navarova, J., Zhukovska, A., Shysh, A., et al. 2011. Myocardial NOS activity and connexin-43 expression in untreated and omega-3 fatty acids-treated spontaneously hypertensive and hereditary hypertriglyceridemic rats. Mol. Cell. Biochem. 347(1-2): 163-173. doi:10.1007/s11010-010-0625-0.PMID:20963625.
    • (2011) Mol. Cell. Biochem , vol.347 , Issue.1-2 , pp. 163-173
    • Radošinská, J.1    Bacova, B.2    Bernatova, I.3    Navarova, J.4    Zhukovska, A.5    Shysh, A.6
  • 33
    • 80055113760 scopus 로고    scopus 로고
    • Alterations of intercellular coupling protein, connexin-43, during ventricular fibrillation and sinus rhythm restoration demonstrated in male and female rat hearts
    • PMID:22131853
    • Radošinská, J., Knezl, V., Benova, T., Urban, L., Tribulová, N., and Slezak, J. 2011. Alterations of intercellular coupling protein, connexin-43, during ventricular fibrillation and sinus rhythm restoration demonstrated in male and female rat hearts. Exp. Clin. Cardiol. 16(4): 116-120.PMID:22131853.
    • (2011) Exp. Clin. Cardiol , vol.16 , Issue.4 , pp. 116-120
    • Radošinská, J.1    Knezl, V.2    Benova, T.3    Urban, L.4    Tribulová, N.5    Slezak, J.6
  • 34
    • 33745256773 scopus 로고    scopus 로고
    • Connexins, conduction, and atrial fibrillation
    • doi:10.1056/NEJMe068088.PMID:16790707
    • Saffitz, J.E. 2006. Connexins, conduction, and atrial fibrillation. N. Engl. J. Med. 354(25): 2712-2714. doi:10.1056/NEJMe068088.PMID:16790707.
    • (2006) N. Engl. J. Med , vol.354 , Issue.25 , pp. 2712-2714
    • Saffitz, J.E.1
  • 35
    • 28944437893 scopus 로고    scopus 로고
    • Pharmacology of Gap junctions. New pharmacological targets for treatment of arrhythmia, seizure and cancer?
    • PMID: 16216217
    • Salameh, A., and Dhein, S. 2005. Pharmacology of Gap junctions. New pharmacological targets for treatment of arrhythmia, seizure and cancer? Biochim. Biophys. Acta, 1719(1-2): 36-58.PMID: 16216217.
    • (2005) Biochim. Biophys. Acta , vol.1719 , Issue.1-2 , pp. 36-58
    • Salameh, A.1    Dhein, S.2
  • 36
    • 51749110724 scopus 로고    scopus 로고
    • Remodelling of gap junctions and connexin expression in diseased myocardium
    • doi:10.1093/cvr/ cvn133.PMID:18519446
    • Severs, N.J., Bruce, A.F., Dupont, E., and Rothery, S. 2008. Remodelling of gap junctions and connexin expression in diseased myocardium. Cardiovasc. Res. 80(1): 9-19. doi:10.1093/cvr/ cvn133.PMID:18519446.
    • (2008) Cardiovasc. Res , vol.80 , Issue.1 , pp. 9-19
    • Severs, N.J.1    Bruce, A.F.2    Dupont, E.3    Rothery, S.4
  • 37
    • 78049243976 scopus 로고    scopus 로고
    • Simvastatin attenuates cardiopulmonary bypass-induced myocardial inflammatory injury in rats by activating peroxisome proliferator-activated receptor g
    • doi:10.1016/j.ejphar.2010.08.058.PMID:20858481
    • Shen, Y., Wu, H., Wang, C., Shao, H., Huang, H., Jing, H., and Li, D. 2010. Simvastatin attenuates cardiopulmonary bypass-induced myocardial inflammatory injury in rats by activating peroxisome proliferator-activated receptor g. Eur. J. Pharmacol. 649(1-3): 255-262. doi:10.1016/j.ejphar.2010.08.058.PMID:20858481.
    • (2010) Eur. J. Pharmacol , vol.649 , Issue.1-3 , pp. 255-262
    • Shen, Y.1    Wu, H.2    Wang, C.3    Shao, H.4    Huang, H.5    Jing, H.6    Li, D.7
  • 38
    • 77957286607 scopus 로고    scopus 로고
    • Remodelling of the heart and vessels in experimental hypertension: Advances in protection
    • doi:10.1097/01.hjh.0000388487. 43460.db.PMID:20823710
    • Simko, F., and Pechanova, O. 2010. Remodelling of the heart and vessels in experimental hypertension: advances in protection. J. Hypertens. 28(1 SUPPL. 1): 1-6. doi:10.1097/01.hjh.0000388487. 43460.db.PMID:20823710.
    • (2010) J. Hypertens , vol.28 , Issue.1 SUPPL. 1 , pp. 1-6
    • Simko, F.1    Pechanova, O.2
  • 39
    • 74949132242 scopus 로고    scopus 로고
    • Limited forward trafficking of connexin 43 reduces cell-cell coupling in stressed human and mouse myocardium
    • doi:10.1172/JCI39740.PMID:20038810
    • Smyth, J.W., Hong, T.T., Gao, D., Vogan, J.M., Jensen, B.C., Fong, T.S., et al. 2010. Limited forward trafficking of connexin 43 reduces cell-cell coupling in stressed human and mouse myocardium. J. Clin. Invest. 120(1): 266-279. doi:10.1172/JCI39740.PMID:20038810.
    • (2010) J. Clin. Invest , vol.120 , Issue.1 , pp. 266-279
    • Smyth, J.W.1    Hong, T.T.2    Gao, D.3    Vogan, J.M.4    Jensen, B.C.5    Fong, T.S.6
  • 40
    • 79959252313 scopus 로고    scopus 로고
    • Dietary red palm oil supplementation decreases infarct size in cholesterol fed rats
    • PMID:21689423
    • Szucs, G., Bester, D.J., Kupai, K., Csont, T., Csonka, C., Esterhuyse, A.J., et al. 2011. Dietary red palm oil supplementation decreases infarct size in cholesterol fed rats. Lipids Health Dis. 10(103): 1-7.PMID:21689423.
    • (2011) Lipids Health Dis , vol.10 , Issue.103 , pp. 1-7
    • Szucs, G.1    Bester, D.J.2    Kupai, K.3    Csont, T.4    Csonka, C.5    Esterhuyse, A.J.6
  • 41
    • 0347934372 scopus 로고    scopus 로고
    • Structural substrates involved in the development of severe arrhythmias in hypertensive rat and aged guinea pig hearts
    • Edited by P.K. Singal, I. Dixon, L. Kirschenbaum, and N.S. Dhalla, Kluwer Academic Publishers, Boston, Mass, doi:10.1007/978-1-4419-9262-8_27
    • Tribulová, N., Okruhlicova, L., Varond, D., Manoach, M., Pecha-nova, O., Bernatova, I., et al. 2002. Structural substrates involved in the development of severe arrhythmias in hypertensive rat and aged guinea pig hearts. In Progress in Experimental Cardiology, 1: Vol. 5, Cardiac Remodelling and Failure III. Edited by P.K. Singal, I. Dixon, L. Kirschenbaum, and N.S. Dhalla. pp 377-398. Kluwer Academic Publishers, Boston, Mass. doi:10.1007/978-1-4419-9262-8_27.
    • (2002) Progress In Experimental Cardiology, 1: Vol. 5, Cardiac Remodelling and Failure III , pp. 377-398
    • Tribulová, N.1    Okruhlicova, L.2    Varond, D.3    Manoach, M.4    Pecha-Nova, O.5    Bernatova, I.6
  • 42
    • 18344396577 scopus 로고    scopus 로고
    • Hypertension-related intermyocyte junction remodelling is associated with a higher incidence of low-K(+)-induced lethal arrhythmias in isolated rat heart
    • doi:10.1113/eph8702336.PMID:11856964
    • Tribulová, N., Okruhlicova, L., Novakova, S., Pancza, D., Bernatova, I., Pechanova, O., et al. 2002a. Hypertension-related intermyocyte junction remodelling is associated with a higher incidence of low-K(+)-induced lethal arrhythmias in isolated rat heart. Exp. Physiol. 87(2): 195-205. doi:10.1113/eph8702336.PMID:11856964.
    • (2002) Exp. Physiol , vol.87 , Issue.2 , pp. 195-205
    • Tribulová, N.1    Okruhlicova, L.2    Novakova, S.3    Pancza, D.4    Bernatova, I.5    Pechanova, O.6
  • 43
    • 0346266097 scopus 로고    scopus 로고
    • Factors involved in the susceptibility of spontaneously hypertensive rats to low K+-induced arrhythmias
    • PMID:14986887
    • Tribulová, N., Okruhlicova, L., Imanaga, I., Hirosawa, N., Ogawa, K., and Weismann, P. 2003. Factors involved in the susceptibility of spontaneously hypertensive rats to low K+-induced arrhythmias. Gen. Physiol. Biophys. 22(3): 369-382.PMID:14986887.
    • (2003) Gen. Physiol. Biophys , vol.22 , Issue.3 , pp. 369-382
    • Tribulová, N.1    Okruhlicova, L.2    Imanaga, I.3    Hirosawa, N.4    Ogawa, K.5    Weismann, P.6
  • 44
    • 45949095953 scopus 로고    scopus 로고
    • Myocardial gap junctions: Targets for novel approaches in the prevention of life-threatening cardiac arrhythmias
    • PMID:18373398
    • Tribulová, N., Knezl, V., Okruhlicová, L., and Slezák, J. 2008. Myocardial gap junctions: targets for novel approaches in the prevention of life-threatening cardiac arrhythmias. Physiol. Res. 57(2): 1-13.PMID:18373398.
    • (2008) Physiol. Res , vol.57 , Issue.2 , pp. 1-13
    • Tribulová, N.1    Knezl, V.2    Okruhlicová, L.3    Slezák, J.4
  • 46
    • 46049087588 scopus 로고    scopus 로고
    • Health benefits of a natural carotenoid rich oil: A proposed mechanism of protection against ischaemia/reperfusion injury
    • PMID: 18296367
    • van Rooyen, J., Esterhuyse, A.J., Engelbrecht, A.-M., and Du Toit, E.F. 2008. Health benefits of a natural carotenoid rich oil: a proposed mechanism of protection against ischaemia/reperfusion injury. Asia Pac. J. Clin. Nutr. 17(1 SUPPL. 1): 316-319.PMID: 18296367.
    • (2008) Asia Pac. J. Clin. Nutr , vol.17 , Issue.1 SUPPL. 1 , pp. 316-319
    • van Rooyen, J.1    Esterhuyse, A.J.2    Engelbrecht, A.-M.3    du Toit, E.F.4


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