메뉴 건너뛰기




Volumn 60, Issue 1, 2012, Pages 197-204

Effect of resveratrol and modulation of cytokine production on human periodontal ligament cells

Author keywords

Cytokines; Human periodontal ligament cells; Resveratrol

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CYTOKINE; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; NITRIC OXIDE; NITRITE; RESVERATROL; TUMOR NECROSIS FACTOR ALPHA;

EID: 84865428973     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2012.06.004     Document Type: Article
Times cited : (45)

References (57)
  • 1
    • 0031152001 scopus 로고    scopus 로고
    • The host response to the microbial challenge in periodontitis: assembling the players
    • Kornman K.S., Page R.C., Tonetti M.S. The host response to the microbial challenge in periodontitis: assembling the players. Periodontology 1997, 2000(14):33-53.
    • (1997) Periodontology , vol.2000 , Issue.14 , pp. 33-53
    • Kornman, K.S.1    Page, R.C.2    Tonetti, M.S.3
  • 2
    • 0028457301 scopus 로고
    • The protective nature of host responses in periodontal diseases
    • Ebersole J.L., Taubman M.A. The protective nature of host responses in periodontal diseases. Periodontology 1994, 2000(5):112-141.
    • (1994) Periodontology , vol.2000 , Issue.5 , pp. 112-141
    • Ebersole, J.L.1    Taubman, M.A.2
  • 3
    • 0032468328 scopus 로고    scopus 로고
    • Cytokine expression in periodontal health and disease
    • Okada H., Murakami S. Cytokine expression in periodontal health and disease. Crit Rev Oral Biol Med 1998, 9:248-266.
    • (1998) Crit Rev Oral Biol Med , vol.9 , pp. 248-266
    • Okada, H.1    Murakami, S.2
  • 4
    • 0033069584 scopus 로고    scopus 로고
    • Biological mediators for periodontal regeneration
    • Cochran D.L., Wozney J.M. Biological mediators for periodontal regeneration. Periodontology 1999, 2000(19):40-58.
    • (1999) Periodontology , vol.2000 , Issue.19 , pp. 40-58
    • Cochran, D.L.1    Wozney, J.M.2
  • 5
    • 0347540289 scopus 로고    scopus 로고
    • Periodontal epithelium: a newly recognized role in health and disease
    • Dale B.A. Periodontal epithelium: a newly recognized role in health and disease. Periodontology 2002, 2000(30):70-78.
    • (2002) Periodontology , vol.2000 , Issue.30 , pp. 70-78
    • Dale, B.A.1
  • 6
    • 33744810061 scopus 로고    scopus 로고
    • Protective and destructive immunity in the periodontium: Part 1 - Innate and humoral immunity and the periodontium
    • Teng Y.T. Protective and destructive immunity in the periodontium: Part 1 - Innate and humoral immunity and the periodontium. J Dent Res 2006, 85:198-208.
    • (2006) J Dent Res , vol.85 , pp. 198-208
    • Teng, Y.T.1
  • 8
    • 0031766801 scopus 로고    scopus 로고
    • Life below the gum line: pathogenic mechanisms of Porphyromonas gingivalis
    • Lamont R.J., Jenkinson H.F. Life below the gum line: pathogenic mechanisms of Porphyromonas gingivalis. Microbiol Mol Biol Rev 1998, 62:1244-1263.
    • (1998) Microbiol Mol Biol Rev , vol.62 , pp. 1244-1263
    • Lamont, R.J.1    Jenkinson, H.F.2
  • 10
    • 0036668593 scopus 로고    scopus 로고
    • Factors that modulate the effects of bone morphogenetic protein-induced periodontal regeneration: a critical review
    • King G.N., Cochran D.L. Factors that modulate the effects of bone morphogenetic protein-induced periodontal regeneration: a critical review. J Periodontol 2002, 73:925-936.
    • (2002) J Periodontol , vol.73 , pp. 925-936
    • King, G.N.1    Cochran, D.L.2
  • 12
    • 33644867216 scopus 로고    scopus 로고
    • Host-mediated resolution of inflammation in periodontal diseases
    • Kantarci A., Hasturk H., Van Dyke T.E. Host-mediated resolution of inflammation in periodontal diseases. Periodontology 2006, 2000(40):144-163.
    • (2006) Periodontology , vol.2000 , Issue.40 , pp. 144-163
    • Kantarci, A.1    Hasturk, H.2    Van Dyke, T.E.3
  • 13
    • 0026701521 scopus 로고
    • Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence
    • Block G., Patterson B., Subar A. Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence. Nutr Cancer 1992, 18:1-29.
    • (1992) Nutr Cancer , vol.18 , pp. 1-29
    • Block, G.1    Patterson, B.2    Subar, A.3
  • 14
    • 0028305595 scopus 로고
    • Diet and health: what should we eat?
    • Willett W.C. Diet and health: what should we eat?. Science 1994, 264:532-537.
    • (1994) Science , vol.264 , pp. 532-537
    • Willett, W.C.1
  • 15
    • 33745962138 scopus 로고    scopus 로고
    • Therapeutic potential of resveratrol: the in vivo evidence
    • Baur J.A., Sinclair D.A. Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov 2006, 5:493-506.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 493-506
    • Baur, J.A.1    Sinclair, D.A.2
  • 16
    • 0036297527 scopus 로고    scopus 로고
    • Cancer chemopreventive activity of resveratrol
    • Bhat K.P., Pezzuto J.M. Cancer chemopreventive activity of resveratrol. Ann NY Acad Sci 2002, 957:210-229.
    • (2002) Ann NY Acad Sci , vol.957 , pp. 210-229
    • Bhat, K.P.1    Pezzuto, J.M.2
  • 17
    • 0031561513 scopus 로고    scopus 로고
    • Cancer chemopreventive activity of resveratrol, a natural product derived from grapes
    • Jang M., Cai L., Udeani G.O., Slowing K.V., Thomas C.F., Beecher C.W., et al. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science 1997, 275:218-220.
    • (1997) Science , vol.275 , pp. 218-220
    • Jang, M.1    Cai, L.2    Udeani, G.O.3    Slowing, K.V.4    Thomas, C.F.5    Beecher, C.W.6
  • 18
    • 10344228747 scopus 로고    scopus 로고
    • Resveratrol inhibits nitric oxide and TNF-alpha production by lipopolysaccharide-activated microglia
    • Bi X.L., Yang J.Y., Dong Y.X., Wang J.M., Cui Y.H., Ikeshima T., et al. Resveratrol inhibits nitric oxide and TNF-alpha production by lipopolysaccharide-activated microglia. Int Immunopharmacol 2005, 5:185-193.
    • (2005) Int Immunopharmacol , vol.5 , pp. 185-193
    • Bi, X.L.1    Yang, J.Y.2    Dong, Y.X.3    Wang, J.M.4    Cui, Y.H.5    Ikeshima, T.6
  • 19
    • 0001889001 scopus 로고    scopus 로고
    • Ferric antimicrobial properties of nitric oxide
    • Kluwer Academic Plenum, New York, NY, F.C. Fang (Ed.)
    • DeGroote M.A., Fang C.F. Ferric antimicrobial properties of nitric oxide. Nitric oxide and infection 2000, 231-261. Kluwer Academic Plenum, New York, NY. F.C. Fang (Ed.).
    • (2000) Nitric oxide and infection , pp. 231-261
    • DeGroote, M.A.1    Fang, C.F.2
  • 20
    • 0034255209 scopus 로고    scopus 로고
    • Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens
    • Nathan C., Shiloh M.U. Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens. Proc Natl Acad Sci USA 2000, 97:8841-8848.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 8841-8848
    • Nathan, C.1    Shiloh, M.U.2
  • 21
    • 0027319441 scopus 로고
    • Copper-dependent antioxidase defenses in inflammatory and autoimmune rheumatic diseases
    • Miesel R., Zuber M. Copper-dependent antioxidase defenses in inflammatory and autoimmune rheumatic diseases. Inflammation 1993, 17:283-294.
    • (1993) Inflammation , vol.17 , pp. 283-294
    • Miesel, R.1    Zuber, M.2
  • 22
    • 0024994816 scopus 로고
    • Role of eicosanoids as mediators of inflammation in inflammatory bowel disease
    • Stenson W.F. Role of eicosanoids as mediators of inflammation in inflammatory bowel disease. Scand J Gastroenterol Suppl 1990, 172:13-18.
    • (1990) Scand J Gastroenterol Suppl , vol.172 , pp. 13-18
    • Stenson, W.F.1
  • 23
    • 0028903154 scopus 로고
    • Cholera toxin and Salmonella typhimurium induce different cytokine profiles in the gastrointestinal tract
    • Klimpel G.R., Asuncion M., Haithcoat J., Niesel D.W. Cholera toxin and Salmonella typhimurium induce different cytokine profiles in the gastrointestinal tract. Infect Immun 1995, 63:1134-1147.
    • (1995) Infect Immun , vol.63 , pp. 1134-1147
    • Klimpel, G.R.1    Asuncion, M.2    Haithcoat, J.3    Niesel, D.W.4
  • 24
    • 0027227735 scopus 로고
    • Controlled-release local delivery antimicrobials in periodontics: prospects for the future
    • Kornman K.S. Controlled-release local delivery antimicrobials in periodontics: prospects for the future. J Periodontol 1993, 64:782-791.
    • (1993) J Periodontol , vol.64 , pp. 782-791
    • Kornman, K.S.1
  • 26
    • 0020590029 scopus 로고
    • Procedure for isolation of bacterial lipopolysaccharides from both smooth and rough Pseudomonas aeruginosa and Salmonella typhimurium strains
    • Darveau R.P., Hancock R.E. Procedure for isolation of bacterial lipopolysaccharides from both smooth and rough Pseudomonas aeruginosa and Salmonella typhimurium strains. J Bacteriol 1983, 155:831-838.
    • (1983) J Bacteriol , vol.155 , pp. 831-838
    • Darveau, R.P.1    Hancock, R.E.2
  • 27
    • 0033981499 scopus 로고    scopus 로고
    • Effects of opsonization and gamma interferon on growth of Brucella melitensis 16M in mouse peritoneal macrophages in vitro
    • Eze M.O., Yuan L., Crawford R.M., Paranavitana C.M., Hadfield T.L., Bhattacharjee A.K., et al. Effects of opsonization and gamma interferon on growth of Brucella melitensis 16M in mouse peritoneal macrophages in vitro. Infect Immun 2000, 68:257-263.
    • (2000) Infect Immun , vol.68 , pp. 257-263
    • Eze, M.O.1    Yuan, L.2    Crawford, R.M.3    Paranavitana, C.M.4    Hadfield, T.L.5    Bhattacharjee, A.K.6
  • 28
    • 20644434164 scopus 로고    scopus 로고
    • Etiology and pathogenesis of periodontal diseases
    • Tatakis D.N., Kumar P.S. Etiology and pathogenesis of periodontal diseases. Dent Clin North Am 2005, 49:491-516.
    • (2005) Dent Clin North Am , vol.49 , pp. 491-516
    • Tatakis, D.N.1    Kumar, P.S.2
  • 29
    • 0034201091 scopus 로고    scopus 로고
    • Occurrence of Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, and Prevotella intermedia in progressive adult periodontitis
    • López N.J. Occurrence of Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, and Prevotella intermedia in progressive adult periodontitis. J Periodontology 2000, 71:948-954.
    • (2000) J Periodontology , vol.71 , pp. 948-954
    • López, N.J.1
  • 30
    • 62149139368 scopus 로고    scopus 로고
    • Tetracyclines and chemically modified tetracycline-3 (CMT-3) modulate cytokine secretion by lipopolysaccharide-stimulated whole blood
    • Cazalis J., Tanabe S., Gagnon G., Sorsa T., Grenier D. Tetracyclines and chemically modified tetracycline-3 (CMT-3) modulate cytokine secretion by lipopolysaccharide-stimulated whole blood. Inflammation 2009, 32:130-137.
    • (2009) Inflammation , vol.32 , pp. 130-137
    • Cazalis, J.1    Tanabe, S.2    Gagnon, G.3    Sorsa, T.4    Grenier, D.5
  • 32
    • 4544375309 scopus 로고    scopus 로고
    • Green tea polyphenols prevent toxin-induced hepatotoxicity in mice by down-regulating inducible nitric oxide-derived prooxidants
    • Chen J.H., Tipoe G.L., Liong E.C., So H.S., Leung K.M., Tom W.M., et al. Green tea polyphenols prevent toxin-induced hepatotoxicity in mice by down-regulating inducible nitric oxide-derived prooxidants. Am J Clin Nutr 2004, 80:742-751.
    • (2004) Am J Clin Nutr , vol.80 , pp. 742-751
    • Chen, J.H.1    Tipoe, G.L.2    Liong, E.C.3    So, H.S.4    Leung, K.M.5    Tom, W.M.6
  • 33
    • 29144534694 scopus 로고    scopus 로고
    • Resveratrol inhibits vascular smooth muscle cell proliferation and induces apoptosis
    • Poussier B., Cordova A.C., Becquemin J.P., Sumpio B.E. Resveratrol inhibits vascular smooth muscle cell proliferation and induces apoptosis. J Vasc Surg 2005, 42:1190-1197.
    • (2005) J Vasc Surg , vol.42 , pp. 1190-1197
    • Poussier, B.1    Cordova, A.C.2    Becquemin, J.P.3    Sumpio, B.E.4
  • 34
    • 34648830916 scopus 로고    scopus 로고
    • Anti-inflammatory responses of resveratrol
    • Das S., Das D.K. Anti-inflammatory responses of resveratrol. Inflamm Allergy Drug Targets 2007, 6:168-173.
    • (2007) Inflamm Allergy Drug Targets , vol.6 , pp. 168-173
    • Das, S.1    Das, D.K.2
  • 35
    • 33750532308 scopus 로고    scopus 로고
    • Regulation of inflammation and redox signaling by dietary polyphenols
    • Rahman I., Biswas S.K., Kirkham P.A. Regulation of inflammation and redox signaling by dietary polyphenols. Biochem Pharmacol 2006, 72:1439-1452.
    • (2006) Biochem Pharmacol , vol.72 , pp. 1439-1452
    • Rahman, I.1    Biswas, S.K.2    Kirkham, P.A.3
  • 36
    • 0036022479 scopus 로고    scopus 로고
    • Effects of antimicrobial agents on spontaneous and endotoxin-induced cytokine release of human peripheral blood mononuclear cells
    • Krehmeier U., Bardenheuer M., Voggenreiter G., Obertacke U., Schade F.U., Majetschak M. Effects of antimicrobial agents on spontaneous and endotoxin-induced cytokine release of human peripheral blood mononuclear cells. J Infect Chemother 2002, 8:194-197.
    • (2002) J Infect Chemother , vol.8 , pp. 194-197
    • Krehmeier, U.1    Bardenheuer, M.2    Voggenreiter, G.3    Obertacke, U.4    Schade, F.U.5    Majetschak, M.6
  • 37
    • 0032113998 scopus 로고    scopus 로고
    • Modulation of basal and post-ischemic leukocyte-endothelial adherence by NO
    • Gidday J.M., Park T.S., Shah A.R., Gonzales E.R. Modulation of basal and post-ischemic leukocyte-endothelial adherence by NO. Stroke 1998, 29:1423-1429.
    • (1998) Stroke , vol.29 , pp. 1423-1429
    • Gidday, J.M.1    Park, T.S.2    Shah, A.R.3    Gonzales, E.R.4
  • 40
    • 33750513819 scopus 로고    scopus 로고
    • Resveratrol exerts its antiproliferative effect on HepG2 hepatocellular carcinoma cells, by inducing cell cycle arrest, and NOS activation
    • Notas G., Nifli A.P., Kampa M., Vercauteren J., Kouroumalis E., Castanas E. Resveratrol exerts its antiproliferative effect on HepG2 hepatocellular carcinoma cells, by inducing cell cycle arrest, and NOS activation. Biochim Biophys Acta 2006, 1760:1657-1666.
    • (2006) Biochim Biophys Acta , vol.1760 , pp. 1657-1666
    • Notas, G.1    Nifli, A.P.2    Kampa, M.3    Vercauteren, J.4    Kouroumalis, E.5    Castanas, E.6
  • 41
    • 0033953297 scopus 로고    scopus 로고
    • Anti-oxidants as modulators of immune function
    • De la Fuente M., Victor V.M. Anti-oxidants as modulators of immune function. Immunol Cell Biol 2000, 78:49-54.
    • (2000) Immunol Cell Biol , vol.78 , pp. 49-54
    • De la Fuente, M.1    Victor, V.M.2
  • 42
    • 79151471604 scopus 로고    scopus 로고
    • Effect of resveratrol and quercetin in experimental infection by Salmonella enterica serovar Typhimurium
    • Paolillo R., Carratelli C.R., Rizzo A. Effect of resveratrol and quercetin in experimental infection by Salmonella enterica serovar Typhimurium. Int Immunopharmacol 2011, 11:149-156.
    • (2011) Int Immunopharmacol , vol.11 , pp. 149-156
    • Paolillo, R.1    Carratelli, C.R.2    Rizzo, A.3
  • 43
    • 0032765131 scopus 로고    scopus 로고
    • Interleukin-1 and tumor necrosis factor activities partially account for calvarial bone resorption induced by local injection of lipopolysaccharide
    • Chiang C.Y., Kyritsis G., Graves D.T., Amar S. Interleukin-1 and tumor necrosis factor activities partially account for calvarial bone resorption induced by local injection of lipopolysaccharide. Infect Immun 1999, 67:4231-4236.
    • (1999) Infect Immun , vol.67 , pp. 4231-4236
    • Chiang, C.Y.1    Kyritsis, G.2    Graves, D.T.3    Amar, S.4
  • 44
    • 0031152114 scopus 로고    scopus 로고
    • Cytokines and prostaglandins in immune homeostasis and tissue destruction in periodontal disease
    • Gemmell E., Marshall R.I., Seymour G.J. Cytokines and prostaglandins in immune homeostasis and tissue destruction in periodontal disease. Periodontology 1997, 2000(145):112-143.
    • (1997) Periodontology , vol.2000 , Issue.145 , pp. 112-143
    • Gemmell, E.1    Marshall, R.I.2    Seymour, G.J.3
  • 45
    • 0034305350 scopus 로고    scopus 로고
    • Levels of interleukin-1 beta, -8, and -10 and RANTES in gingival crevicular fluid and cell populations in adult periodontitis patients and the effect of periodontal treatment
    • Gamonal J., Acevedo A., Bascones A., Jorge O., Silva A. Levels of interleukin-1 beta, -8, and -10 and RANTES in gingival crevicular fluid and cell populations in adult periodontitis patients and the effect of periodontal treatment. J Periodontol 2000, 71:1535-1545.
    • (2000) J Periodontol , vol.71 , pp. 1535-1545
    • Gamonal, J.1    Acevedo, A.2    Bascones, A.3    Jorge, O.4    Silva, A.5
  • 46
    • 0031543387 scopus 로고    scopus 로고
    • Quantitative assessment of inflammatory cytokine gene expression in chronic adult periodontitis
    • Roberts F.A., Hockett R.D., Bucy R.P., Michalek S.M. Quantitative assessment of inflammatory cytokine gene expression in chronic adult periodontitis. Oral Microbiol Immunol 1997, 12:336-344.
    • (1997) Oral Microbiol Immunol , vol.12 , pp. 336-344
    • Roberts, F.A.1    Hockett, R.D.2    Bucy, R.P.3    Michalek, S.M.4
  • 47
    • 0035503936 scopus 로고    scopus 로고
    • Immunomodulatory activity of resveratrol: suppression of lymphocyte proliferation, development of cell-mediated cytotoxicity, and cytokine production
    • Gao X., Xu Y.X., Janakiraman N., Chapman R.A., Gautam S.C. Immunomodulatory activity of resveratrol: suppression of lymphocyte proliferation, development of cell-mediated cytotoxicity, and cytokine production. Biochem Pharmacol 2001, 62:1299-1308.
    • (2001) Biochem Pharmacol , vol.62 , pp. 1299-1308
    • Gao, X.1    Xu, Y.X.2    Janakiraman, N.3    Chapman, R.A.4    Gautam, S.C.5
  • 48
    • 19644364172 scopus 로고    scopus 로고
    • Production of ex vivo lipopolysaccharide-induced tumor necrosis factor-alpha, interleukin-1beta, and interleukin-6 is suppressed by trans-resveratrol in a concentration-dependent manner
    • Marier J.F., Chen K., Prince P., Scott G., del Castillo J.R., Vachon P. Production of ex vivo lipopolysaccharide-induced tumor necrosis factor-alpha, interleukin-1beta, and interleukin-6 is suppressed by trans-resveratrol in a concentration-dependent manner. Can J Vet Res 2005, 69:151-154.
    • (2005) Can J Vet Res , vol.69 , pp. 151-154
    • Marier, J.F.1    Chen, K.2    Prince, P.3    Scott, G.4    del Castillo, J.R.5    Vachon, P.6
  • 49
    • 0033147239 scopus 로고    scopus 로고
    • Virulence factors of Porphyromonas gingivalis
    • Holt S.C., Kesavalu L., Walker S., Genco C.A. Virulence factors of Porphyromonas gingivalis. Periodontology 1999, 2000(20):168-238.
    • (1999) Periodontology , vol.2000 , Issue.20 , pp. 168-238
    • Holt, S.C.1    Kesavalu, L.2    Walker, S.3    Genco, C.A.4
  • 51
    • 0024404268 scopus 로고
    • Parathyroid hormone (PTH) and PTH-like protein (PLP) stimulate interleukin-6 production by osteogenic cells: a possible role of interleukin-6 in osteoclastogenesis
    • Löwik C.W., van der Pluijm G., Bloys H., Hoekman K., Bijvoet O.L., Aarden L.A., et al. Parathyroid hormone (PTH) and PTH-like protein (PLP) stimulate interleukin-6 production by osteogenic cells: a possible role of interleukin-6 in osteoclastogenesis. Biochem Biophys Res Commun 1989, 162:1546-1552.
    • (1989) Biochem Biophys Res Commun , vol.162 , pp. 1546-1552
    • Löwik, C.W.1    van der Pluijm, G.2    Bloys, H.3    Hoekman, K.4    Bijvoet, O.L.5    Aarden, L.A.6
  • 52
    • 0029916409 scopus 로고    scopus 로고
    • Gastric mucosal inflammatory responses to Helicobacter pylori
    • Crabtree J.E. Gastric mucosal inflammatory responses to Helicobacter pylori. Aliment Pharmacol Ther 1996, 10:29-37.
    • (1996) Aliment Pharmacol Ther , vol.10 , pp. 29-37
    • Crabtree, J.E.1
  • 53
    • 1642405330 scopus 로고    scopus 로고
    • Curcumin blocks NF-kappaB and the motogenic response in Helicobacter pylori-infected epithelial cells
    • Foryst-Ludwig A., Neumann M., Schneider-Brachert W., Naumann M. Curcumin blocks NF-kappaB and the motogenic response in Helicobacter pylori-infected epithelial cells. Biochem Biophys Res Commun 2004, 316:1065-1072.
    • (2004) Biochem Biophys Res Commun , vol.316 , pp. 1065-1072
    • Foryst-Ludwig, A.1    Neumann, M.2    Schneider-Brachert, W.3    Naumann, M.4
  • 54
    • 25844494431 scopus 로고    scopus 로고
    • Generation of inflammatory stimuli: how bacteria set up inflammatory responses in the gingiva
    • Madianos P.N., Bobetsis A., Kinane D.F. Generation of inflammatory stimuli: how bacteria set up inflammatory responses in the gingiva. J Clin Periodontol 2005, 32:57-71.
    • (2005) J Clin Periodontol , vol.32 , pp. 57-71
    • Madianos, P.N.1    Bobetsis, A.2    Kinane, D.F.3
  • 56
    • 0035871615 scopus 로고    scopus 로고
    • IL-12 alone and in synergy with IL-18 inhibits osteoclast formation in vitro
    • Horwood N.J., Elliott J., Martin T.J., Gillespie M.T. IL-12 alone and in synergy with IL-18 inhibits osteoclast formation in vitro. J Immunol 2001, 166:4915-4921.
    • (2001) J Immunol , vol.166 , pp. 4915-4921
    • Horwood, N.J.1    Elliott, J.2    Martin, T.J.3    Gillespie, M.T.4
  • 57
    • 0036270218 scopus 로고    scopus 로고
    • Interleukin-18 and interleukin-12 synergistically inhibit osteoclastic bone-resorbing activity
    • Yamada N., Niwa S., Tsujimura T., Iwasaki T., Sugihara A., Futani H., et al. Interleukin-18 and interleukin-12 synergistically inhibit osteoclastic bone-resorbing activity. Bone 2002, 30:901-908.
    • (2002) Bone , vol.30 , pp. 901-908
    • Yamada, N.1    Niwa, S.2    Tsujimura, T.3    Iwasaki, T.4    Sugihara, A.5    Futani, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.