Chronic estradiol treatment reduces platelet responses and protects mice from thromboembolism through the hematopoietic estrogen receptor α

Blood

Volumn 120, Issue 8, 2012, Pages 1703-1712

  Valéra, Marie Cécile ^a,b   Gratacap, Marie Pierre ^a   Gourdy, Pierre ^a   Lenfant, Françoise ^a   Cabou, Cendrine ^a,b   Toutain, Celine E ^a   Marcellin, Marlene ^b   Laurent, Nathalie Saint ^c   Sié, Pierre ^a,d   Sixou, Michel ^b   Arnal, Jean François ^a   Payrastre, Bernard ^a,d  

^a University Hospital of Toulouse   (France)

^b UNIVERSITÉ PAUL SABATIER   (France)

^c CHU RANGUEIL   (France)

^d TOULOUSE UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION FUNCTION 1; BETA TUBULIN; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; RECEPTOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLEEDING TIME; BONE MARROW TRANSPLANTATION; CAROTID ARTERY THROMBOSIS; CHIMERA; CONTROLLED STUDY; DRUG PELLET; ELECTRON MICROSCOPY; EX VIVO STUDY; FEMALE; FIBRIN CLOT; HISTOCHEMISTRY; IN VIVO STUDY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOUSE; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEOMICS; REGULATORY MECHANISM; THROMBOCYTE ACTIVATION; THROMBOCYTE FUNCTION; THROMBOCYTOPOIESIS; THROMBOEMBOLISM;

EID: 84865428859     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-01-405498     Document Type: Article

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