Protein flexibility is key to cisplatin crosslinking in calmodulin

Protein Science

Volumn 21, Issue 9, 2012, Pages 1269-1279

  Li, Huilin ^a   Wells, Stephen A ^b   Jimenez Roldan, J Emilio ^b   Römer, Rudolf A ^b   Zhao, Yao ^a   Sadler, Peter J ^a   O'Connor, Peter B ^a  

^a UNIVERSITY OF WARWICK   (United Kingdom)

^b UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

Calmodulin; Cisplatin; Flexibility simulation; FTICR MS; Protein crosslinking

Indexed keywords

CALCIUM; CALMODULIN; CISPLATIN;

ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; DRUG PROTEIN BINDING; ELASTICITY; HYDROPHOBICITY; ION CYCLOTRON RESONANCE MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN CROSS LINKING; PROTEIN STRUCTURE; SIMULATION;

ANIMALS; BINDING SITES; CALMODULIN; CATTLE; CISPLATIN; CROSS-LINKING REAGENTS; FOURIER ANALYSIS; MASS SPECTROMETRY; MELITTEN; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 84865410736     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.2111     Document Type: Article

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